As a leading 5-Iodo-3H-Pyrrolo[2,3-D]Pyrimidin-4(7H)-One supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 5-iodo-3h-pyrrolo [2,3-d] pyrimidin-4 (7h) -one?
5-Iodo-3H-pyrrolo [2,3-d] pyrimidin-4 (7H) -one, one of the organic compounds. Its chemical structure can be resolved as follows:
This compound contains a unique fused ring structure, which is formed by fusing the pyrrole ring with the pyrimidine ring. Among them, the pyrrole ring and the pyrimidine ring are fused in a specific [2,3-d] way, which refers to the specific number and position relationship of the two rings connecting the check point.
In this fused ring structure, at the 3H position, the hydrogen atom at the 3rd position of the pyrrole ring exists in a specific chemical environment. At 4 (7H) -one, it is shown that there is a carbonyl group (C = O) at the 4th position of the pyrimidine ring, and the existence form of this carbonyl group is related to 7H, which means that the hydrogen atom at the 7th position interacts with the electron cloud distribution and chemical properties of the carbonyl group.
Furthermore, 5-iodo is shown at the 5th position of the entire fused ring structure, with an iodine atom attached. The iodine atom has a significant impact on the physical and chemical properties of the compound, such as polarity, melting point, and chemical reactivity, due to its large atomic radius and special electron cloud structure.
The overall layout of this chemical structure determines the unique chemical properties and potential application directions of 5-iodo-3H-pyrrolo [2,3-d] pyrimidin-4 (7H) -one, which may be of great significance in organic synthesis, medicinal chemistry and other fields.
What are the main physical properties of 5-iodo-3h-pyrrolo [2,3-d] pyrimidin-4 (7h) -one
5-Iodo-3H-pyrrolo [2,3-d] pyrimidin-4 (7H) -one is an organic compound. Its main physical properties are as follows:
This substance is a solid at room temperature and pressure. Due to the connection and interaction of atoms in the molecule, it has a specific crystal structure. This structure has a significant impact on many of its physical properties.
From the perspective of melting point, its melting point is within a specific range due to the force between molecules. The presence of iodine atoms in the molecule increases the intermolecular force, which requires higher energy to break the lattice and cause the solid to convert into a liquid, so the melting point is relatively high.
In terms of solubility, the compound has different solubility in common organic solvents. Its molecules have a certain polarity. Because they contain electronegative atoms such as nitrogen and oxygen, they can form intermolecular forces with some polar organic solvents. For example, in alcohol solvents, they can form hydrogen bonds with alcohol molecules, so they have a certain solubility in alcohols. However, due to the large proportion of hydrocarbons in the molecule, its solubility in water is not good. Water is a strong polar solvent, and the intermolecular forces with the compound are weak, making it difficult to overcome the intermolecular forces of the compound to disperse it in water.
In appearance, the pure 5-iodo-3H-pyrrolo [2,3-d] pyrimidin-4 (7H) -one is usually white or off-white powder, which is determined by the absorption and scattering properties of the molecule. The electron transition energy level in the molecular structure determines its absorption of light of different wavelengths. In the visible range, the combination of absorbed and reflected light makes the compound exhibit this appearance.
Density is also one of its important physical properties, which is determined by the combination of molecular mass and the degree of molecular packing compactness. The relative atomic mass of iodine atoms in the molecule increases the molecular mass, and the way of molecular packing affects the number of molecules per unit volume, which in turn affects the density. Its density is within a specific numerical range, which is of reference significance for its separation, mixing, and other operations in practical applications.
What are the common synthesis methods of 5-iodo-3h-pyrrolo [2,3-d] pyrimidin-4 (7h) -one?
5-Iodo-3H-pyrrolo [2,3-d] pyrimidin-4 (7H) -one is an important organic compound, and its synthesis methods are diverse. The common synthesis method is to use nitrogen-containing heterocyclic compounds as starting materials and obtain them through multiple steps.
First, it can be started from a specific pyrimidine derivative. First, a specific position on the pyrimidine ring is introduced into the halogen atom through a halogenation reaction. For example, by selecting an appropriate halogenation reagent and reaction conditions, an iodine atom is introduced at a suitable check point in the pyrimidine ring. This step requires precise control of the reaction to avoid the introduction of too many halogen atoms or side reactions. Subsequently, a pyrrole ring is constructed through a cyclization reaction. In this process, the reaction reagents and catalysts, such as specific bases or metal catalysts, need to be carefully selected to promote the smooth closure of the pyrrole ring. This route requires strict control of the reaction conditions, and the temperature, reaction time and reagent dosage all have a great impact on the yield and purity of the product.
Second, pyrrole derivatives can also be used as starters. First modify the pyrrole ring, such as introducing suitable substituents to facilitate the subsequent construction of pyrimidine rings. Through a series of nucleophilic substitution, cyclization and other reactions, the target molecular structure is gradually constructed. In this process, the optimization of the reaction sequence and reaction conditions is extremely critical, such as the activity and selectivity of nucleophilic reagents during nucleophilic substitution reactions, as well as the solvent and temperature during cyclization reactions, all need to be carefully considered to obtain high-purity target products.
Furthermore, there is a synthesis strategy based on multi-component reactions. A variety of simple raw materials are used in a pot reaction through complex reaction mechanisms to construct the target compound in one step. The advantage of this method is that it is easy to operate and has high atomic economy, but the requirements for reaction conditions and raw material ratios are more stringent. In-depth understanding of the mechanism of multi-component reactions is required to effectively regulate the reaction and improve the yield and purity of the product.
The above synthesis methods have their own advantages and disadvantages. In practical applications, the appropriate synthesis path should be carefully selected according to the availability of starting materials, the purity requirements of the target product, and the cost. To efficiently synthesize 5-iodo-3H-pyrrolo [2,3-d] pyrimidin-4 (7H) -one.
In which fields is 5-iodo-3h-pyrrolo [2,3-d] pyrimidin-4 (7h) -one used?
5-Iodine-3H-pyrrolido [2,3-d] pyrimidine-4 (7H) -one is useful in the fields of medicine, pesticides and materials science.
In the field of medicine, this compound can be used as a key intermediate to synthesize anti-cancer drugs. The structure of Gain pyrrolido pyrimidine can tightly bind to specific targets in cancer cells, or can block the signaling pathways related to cancer cell proliferation, thereby inhibiting the growth and spread of cancer cells. For example, by modifying this compound, it can enhance its targeting of cancer cells, reduce damage to normal cells, and improve anti-cancer efficacy.
In the field of pesticides, it may have insecticidal and bactericidal effects. Such nitrogen-containing heterocyclic structures often have effects on the physiological and metabolic processes of the insect nervous system or pathogenic bacteria. Taking some pests as an example, the compound can interfere with their nerve conduction, causing their movement disorders, inhibition of feeding, and eventually death; for pathogens, it may hinder their cell wall synthesis, inhibit respiratory metabolism, and achieve the purpose of sterilization.
In the field of materials science, 5-iodine-3H-pyrrolido [2,3-d] pyrimidine-4 (7H) -ketone can be used to prepare organic optoelectronic materials due to its unique electronic structure and chemical properties. It may exhibit good photoelectric conversion properties in optoelectronic devices, and is expected to be applied to organic solar cells, Light Emitting Diode, etc., providing a possible path for the development of new high-efficiency optoelectronic materials.
What is the market outlook for 5-iodo-3h-pyrrolo [2,3-d] pyrimidin-4 (7h) -one?
5-Iodo-3H-pyrrolo [2,3-d] pyrimidin-4 (7H) -one is a special organic compound. Its market prospects need to be carefully examined from multiple dimensions.
Looking at the field of medicine, this compound may have potential medicinal value. The structure of pyrrolidone ketones shows unique biological activities in the development of many drugs, or can act on specific biological targets, and has potential efficacy in the treatment of certain diseases. However, the road to new drug development is long and full of thorns. It needs to go through rigorous pharmacological experiments, toxicological tests and other barriers to determine whether it can be made into a drug. Only the initial research stage shows that it is active, and it is difficult to say that it will be successfully converted into marketed drugs. Therefore, it will take time and massive research investment to fully spread out in the pharmaceutical market.
In the field of pesticides, compounds containing iodine and such heterocyclic structures may have good insecticidal and bactericidal properties. If this compound can meet such requirements, it is expected to open up a market. However, the pesticide market is highly competitive, and new compounds must outperform existing products in terms of effect, cost and environmental impact if they want to stand out.
In scientific research applications, due to its unique structure, it may be an important intermediate in organic synthetic chemistry. Chemists can create more new compounds by structurally modifying them, providing raw materials for basic research and the development of new drugs and new materials in the chemical field. The scientific research market has a stable demand for novel and unique compounds. If the supply and quality can be ensured, it may be able to occupy a place in the scientific research reagent market.
However, it should be noted that its market prospects are also restricted by many factors. In terms of production, if the synthesis process is complicated and costly, it will greatly limit its large-scale production and marketing activities. At the regulatory level, whether it is medicine, pesticides, or scientific research applications, it is facing strict supervision, and the compliance cost cannot be ignored. And the market dynamics are changing rapidly, and competitors may introduce more advantageous alternatives at any time.
In summary, 5-iodo-3H-pyrrolo [2,3-d] pyrimidin-4 (7H) -one has potential opportunities in the fields of medicine, pesticides and scientific research, but to achieve a good market prospect, it is necessary to overcome multiple challenges such as synthesis, regulations and competition. After careful research and strategic layout, it is possible to achieve success in the market.
![5-Iodo-3H-Pyrrolo[2,3-D]Pyrimidin-4(7H)-One](https://alchemist-1317689233.cos.ap-nanjing.myqcloud.com/a5b4c857-d896-4a64-9dbc-f3b40103b7d4/images/product_inner2.jpg)
