5-iodo-alpha-85380, 5-trimethylstannyl N-boc Derivative

5 - iodo - α - 8 5 380% 2C + 5 - trimethylstannyl N - boc Derivative This compound is an important intermediate in organic synthesis. It has a wide range of uses in the field of organic synthesis.
First, it can act as a key building block in the construction of complex organic molecular structures due to its unique structure. The presence of iodine and trimethyltin in this compound gives it special reactivity. The iodine atom is active and easily participates in nucleophilic substitution reactions. It can interact with many nucleophilic reagents to introduce various functional groups, thereby expanding the complexity of the molecule.
Second, it also plays a key role in metal-catalyzed coupling reactions. For example, in the palladium-catalyzed cross-coupling reaction, 5-iodo - α - 85380% 2C + 5-trimethylstannyl N-boc Derivative can react with different alkenes, aryl halides and other substrates to achieve efficient construction of carbon-carbon bonds, which is of great significance for the synthesis of organic materials and drug molecules with specific structures and functions.
Third, in the field of drug development, as an intermediate, after a series of chemical reactions, it may be converted into bioactive molecules. Its N-boc protecting group can be removed under appropriate conditions, and then the molecule can be further modified and optimized to meet the needs of drug-target interaction, laying the foundation for the creation of new drugs.
Fourth, in the field of materials science, the organic compounds that participate in the synthesis may exhibit special photoelectric properties. After rational design and synthesis, functional materials for organic Light Emitting Diodes, solar cells and other fields may be prepared.

The preparation of 5-iodine-alpha, 5-trimethyltin-based N-Boc derivatives follows the following ancient method:
First, the raw materials need to be prepared, and the high-purity 5-iodine compound and trimethyltin-based reagent should be selected, and the reagent of N-Boc protective base should also be properly prepared. This is the reaction base.
In a clean reactor, carefully create an inert atmosphere with nitrogen to avoid the disturbance of oxygen and water vapor. According to the precise ratio, put 5-iodine compound and trimethyltin-based reagent into the kettle, and add an appropriate amount of acid binding agent to help the reaction balance advance. Acid binding agent, or an organic base such as triethylamine, neutralizes the acid generated by the reaction.
Choose suitable organic solvents, such as anhydrous tetrahydrofuran, dichloromethane, etc., so that the raw materials are fully dissolved, and a homogeneous reaction system is constructed to facilitate molecular collision and reaction. When the raw materials and solvents are mixed well, the temperature is controlled in a low-temperature bath, and it is slowly reduced to a specific low temperature, usually minus tens of degrees Celsius. When the temperature is controlled, slowly add N-Boc protective base reagents, and the dripping speed is careful to prevent the reaction from overheating.
After the drip is added, it gradually warms up to room temperature, so that the reaction evolves naturally. In the meantime, by thin-layer chromatography or liquid chromatography, the reaction process can be measured frequently to determine the consumption of raw materials and the formation of products. When the raw materials are exhausted, the product formation stabilizes and the reaction The method at the back of
is very important. The reaction liquid is poured into the separation funnel, and an appropriate amount of organic solvent is extracted to transfer the product to the organic phase. Then the organic phase is sequentially polyester with dilute acid, dilute alkali and water to remove unreacted raw materials, by-products and impurities.
After the polyester is completed, the organic phase moisture is removed with a desiccant such as anhydrous sodium sulfate or magnesium sulfate. After filtering and removing the desiccant, the organic solvent is removed by vacuum distillation to obtain the crude product.
The crude product is impure and needs to be refined. The recoverable column chromatography method selects the appropriate silica gel and the eluent, and separates them according to the polarity of the product and the impurities. Under proper operation, pure 5-iodine-α, 5-trimethyltin-N-Boc derivatives are obtained. The whole process requires strict compliance with the operating procedures and fine control of each step to obtain good results.

5 - iodo - α - 8 5 380% 2C + 5 - trimethylstannyl N - boc Derivative is an organic compound, and its physicochemical properties are quite important.
When it comes to physical properties, at room temperature, this substance may be in a solid state, due to the fact that organotin and iodine substitutes often have high melting points. Looking at its appearance, it may be a white to light yellow crystalline powder. This color and morphology are derived from molecular structure and intermolecular interactions. Its melting point may be in a specific range, but the exact value varies depending on impurities and measurement conditions. The solubility of this substance is also critical. It may have good solubility in organic solvents such as dichloromethane and chloroform. Due to the fact that organic groups in the molecular structure are similar to organic solvents in dissolution; in water, the solubility may be poor, because the molecular polarity is not enough to form a strong interaction with water.
As for the chemical properties, iodine atoms are highly active and easily participate in nucleophilic substitution reactions. In this compound, iodine atoms can be replaced by various nucleophilic reagents to form new organic compounds, enriching the organic synthesis path. The organotin part is also active and can participate in many reactions in metal-organic chemistry, such as Stille coupling reactions, which are coupled with halogenated aromatics or olefins under the action of catalysts to form carbon-carbon bonds, providing a powerful means for the synthesis of complex organic molecules. The N-boc group has the function of protecting amino groups, which can be removed under appropriate conditions, allowing amino groups to participate in subsequent reactions and improving the flexibility of compound synthesis.
The physicochemical properties of this compound lay the foundation for research and application in organic synthesis and related fields, helping researchers to deeply understand and use its properties to achieve specific synthetic goals.

I don't know what is the status of "5-iodo-alpha-85380% 2C + 5-trimethylstannyl N-boc Derivative". This compound is unusual, and its performance is affected by many factors.
First, it is easy to be important. If the synthesis requires complex steps, special or harsh components, the cost must be high, and the price will rise. For example, rare gold catalysis or ultra-low-temperature environments are required, which is not cheap to use.
Second, the degree of resistance also depends. High-quality products are mostly needed in scientific research or refining chemicals, and their degree of improvement is large, so it is high. 99% 95%, the difference can be huge.
Furthermore, the supply and demand of the market also have an impact. If there are multiple enterprises working or researching each other, but the supply is limited, they will be sold; if the demand is weak, the producers will sell it, or reduce it.
In addition, the suppliers are different, and there are also costs. Large suppliers have low costs due to their efficiency; small suppliers or due to cost, etc., the price is slightly higher.
If you want to know the market, you need chemical raw material suppliers, chemical sales platforms, or recent transactions with the same product to get the best.

5 - iodo - alpha - 85380% 2C + 5 - trimethylstannyl N - boc derivatives, this is a very special chemical substance, and its storage conditions are crucial.
Such substances need to be stored in a very dry place. Due to the water vapor in the air, it is very easy to react with it, causing its chemical properties to change, which in turn affects its quality and effectiveness. Therefore, the storage place should have excellent moisture-proof facilities, such as the use of desiccants, to ensure a dry environment.
and need to be stored at low temperature. High temperature can easily cause the derivative to decompose and deteriorate. Generally speaking, the storage temperature should be maintained at about -20 ° C, and in some cases, even lower temperatures are required. This low temperature environment can effectively inhibit the activity of its molecules and delay possible chemical reactions.
Furthermore, avoid light. Light, especially strong light, can cause luminescent chemical reactions and cause damage to the structure of the derivative. Therefore, when storing, choose an opaque container, such as a brown glass bottle, or place it in a dark storage space.
In addition, if the derivative comes into contact with other chemical substances, adverse reactions may also occur. Therefore, it needs to be stored separately, and the storage area should be kept away from various oxidants, reducing agents, acids, bases and other substances to prevent dangerous interactions. Only in this way can the 5-iodo-alpha-85380% 2C + 5-trimethylstannyl N-boc derivative be properly preserved to maintain its inherent chemical properties and quality.