What is the chemical structure of 5-iodopyridazin-3 (2h) -one?

The chemical structure of 5-iodopyridazin-3 (2H) -one is as follows. This compound contains the parent nucleus of pyridine pyridazine, which is formed by fusing a six-membered pyridine ring with a pyridazine ring. In this structure, the 3-position of the pyridine pyridazine ring has a carbonyl group (C = O), and the carbonyl is connected to hydrogen in the 2H state, that is, this position is connected to hydrogen to satisfy the tetravalent carbon carbonyl. At the same time, there is an iodine atom (I) attached to the 5-position.

From the perspective of atomic connection, the nitrogen atom of the pyridazine ring is connected to the adjacent carbon atom by covalent bonds to form a stable ring structure. The oxygen atom of the carbonyl group is connected with the carbon atom of the 3 position by a double bond, showing typical carbonyl characteristics. The iodine atom of the 5 position is also firmly connected to the carbon atom of the ring by a covalent bond. This chemical structure endows 5-iodopyridazin-3 (2H) -one with unique physical and chemical properties, and may have important applications in organic synthesis and medicinal chemistry. Because the carbonyl group, iodine atom and nitrogen-containing heterocyclic ring in the structure are all active check points, they can participate in various chemical reactions, such as nucleophilic substitution, oxidation and reduction, etc., laying the foundation for the construction of more complex organic molecules.

What are the main uses of 5-iodopyridazin-3 (2h) -one?

5-Iodopyridazine-3 (2H) -one, which has a wide range of uses in the field of medicine, is a key intermediate for the synthesis of many specific drugs. The structure of geindazine has unique biological activity in pharmaceutical chemistry. After 5-iodine substitution, it can precisely regulate the interaction between drugs and biological targets. For example, in the development of anti-cancer drugs, based on this, new drugs can be designed that can specifically inhibit the proliferation of tumor cells.

It also plays an important role in the field of materials science. It can be used as a building block for organic synthesis to construct materials with special photoelectric properties. By means of ingenious molecular design and chemical synthesis, it can be integrated into the conjugated system, and then new materials with excellent performance in the fields of Light Emitting Diode and solar cells can be prepared. Due to the characteristics of iodine atoms, it can affect the electron cloud distribution and energy level structure of the material, and optimize the photoelectric properties of the material.

In agricultural chemistry, 5-iodopyridazine-3 (2H) -one can be used as a raw material for the synthesis of high-efficiency pesticides. A new type of pesticide with dual functions of insecticide and bactericidal can be developed to provide comprehensive protection for crop growth. Due to its unique chemical structure, it has high selectivity and strong activity against specific pests and diseases, which can ensure crop yield and quality while reducing the adverse impact on the environment, meeting the current needs of green agriculture development.

What are the synthesis methods of 5-iodopyridazin-3 (2h) -one?

The synthesis method of 5-iodopyridazine-3 (2H) -ketone has been known for a long time, and each way has its own wonders.

First, the method of halogenation can be used to obtain 5-iodopyridazine-3 (2H) -ketone from pyridazine-3 (2H) -ketone. First, place pyridazine-3 (2H) -ketone in a suitable reaction vessel, and add an appropriate amount of halogenating reagents, such as iodine and corresponding catalysts. The choice of this catalyst is related to the success or failure of the reaction, and often depends on metal salts or organic bases with specific activities. Under a specific temperature and reaction time, the iodine atom of the halogenated reagent can cleverly replace the hydrogen atom at 5 positions in the pyridazine-3 (2H) -ketone molecule to generate 5-iodopyridazine-3 (2H) -ketone. This process requires precise temperature control. If the temperature is too high, side reactions will occur, and if it is too low, the reaction will be slow and time-consuming.

Second, you can start from a suitable pyridine derivative. After multi-step transformation, the specific position of the pyridine derivative is functionalized first, and groups that can be further transformed are introduced. Through a series of reaction steps such as substitution and cyclization, the pyridazine ring system is carefully constructed. On this basis, the halogenation reaction is carried out, and the iodine atom is introduced into the target position to obtain 5-iodopyridazine-3 (2H) -ketone. Although this approach is complicated, if the reaction conditions of each step are properly controlled, a higher purity product can be obtained.

Third, the use of organometallic reagents is also a method. React with a reagent containing a specific metal with the corresponding halopyridazine derivative. The metal reagent and the halogen undergo metallization to form an active intermediate. This intermediate reacts with the iodine source to introduce the iodine atom into the target position and achieve the synthesis of 5-iodopyridazine-3 (2H) -ketone. However, organometallic reagents are active in nature and require severe conditions for the reaction environment. Anhydrous and oxygen-free conditions are indispensable, otherwise it is easy to cause side reactions and affect product formation.

What are the physical properties of 5-iodopyridazin-3 (2h) -one?

5-Iodopyridazine-3 (2H) -ketone is a kind of organic compound. Its physical properties are quite characteristic, let me tell you in detail.

First of all, its appearance is often in a solid state. Due to the intermolecular force, it maintains a solid state at room temperature and pressure. As for the color, it is mostly white or white-like powder, which is determined by the characteristics of molecular structure on visible light absorption and reflection.

Second, its melting point is about a certain temperature range. This temperature value is determined by the intermolecular force and crystal structure. When the temperature rises to the melting point, the molecule is energized enough to break free from the lattice, and then changes from solid to liquid.

In terms of solubility, in common organic solvents, their solubility varies. In polar organic solvents, such as dimethyl sulfoxide (DMSO), there is a certain solubility. Because the molecule has a certain polarity, it can form intermolecular forces with polar solvents, such as hydrogen bonds, dipole-dipole interactions, etc., to promote its dissolution. In non-polar organic solvents, such as n-hexane, the solubility is very small, because the molecular polarity does not match the non-polar solvent, and the intermolecular force is weak.

Furthermore, its density is also one of the important physical properties. Although the specific value needs to be accurately measured, it can be roughly inferred from its molecular structure and the relative atomic mass of the constituent atoms. In general, its density may be different from that of water, which is related to its distribution in the mixed system.

In addition, the stability of the compound is also a consideration of physical properties. Under normal temperature and pressure and without the action of special chemical reagents, the structure is relatively stable. In case of special conditions such as high temperature, strong oxidizing agent or reducing agent, a chemical reaction may occur, resulting in structural changes. This stability is derived from the strength of the chemical bonds within the molecule and the rationality of the spatial structure. In conclusion, the physical properties of 5-iodopyridazine-3 (2H) -one are restricted by many factors such as molecular structure, constituent atoms and intermolecular forces. It is clear that these properties are of great significance in their synthesis, separation, purification and application.

What is the price of 5-iodopyridazin-3 (2h) -one in the market?

5-Iodopyridazin-3 (2H) -one is also an organic compound. To know its price in the market, it is difficult to say for sure at present. The price of organic compounds often varies due to various factors, such as the state of supply and demand, the difficulty of preparation, the difference in quality, and the movement of market conditions.

Looking at the market in the past, the price of organic compounds, supply and demand are the main factors. If there are many applicants for this product, and there are few suppliers, the price will rise; on the contrary, if the supply exceeds the demand, the price will decline. The difficulty of preparation also affects the price. If the preparation method and high cost are required, the price will also be higher. The quality is also about the price. Those with high purity often exceed those with low purity.

However, I have searched all over the ancient books, but I have not found the exact current market price of 5-iodopyridazin-3 (2H) -one. For details, you can visit the market where chemicals are traded, consult merchants, or refer to the platform for professional chemical price information. In this way, you may get near real-time and accurate price information, which helps you understand the market value of this product.