5 Methoxy 2 Iodobenzoic Acid
Iodobenzene

5-methoxy-2-iodobenzoic Acid

Fengxi Chemical

Specifications

HS Code

381834

Chemical Formula C8H7IO3
Molar Mass 280.04 g/mol
Appearance Solid
Melting Point 158 - 160 °C
Solubility In Water Low
Solubility In Organic Solvents Soluble in common organic solvents like DMSO, DMF
Pka Value Around 3 - 4 (estimated for carboxylic acid group)
Boiling Point Decomposes before boiling
Chemical Formula C8H7IO3
Molar Mass 280.04 g/mol
Appearance Solid (likely white or off - white)
Solubility In Water Low solubility
Solubility In Organic Solvents Soluble in some organic solvents like ethanol, dichloromethane
Melting Point Typically in a certain range (needs experimental determination, around 140 - 150°C approximately)
Pka Value Around 3 - 4 (estimate for the carboxylic acid group)
Density Needs experimental determination, density is related to its solid - state packing
Reactivity Reactive towards nucleophiles due to the presence of carboxylic acid and iodine groups
Chemical Formula C8H7IO3
Molar Mass 280.044 g/mol
Appearance Solid (likely white or off - white)
Solubility In Water Low solubility (aromatic carboxylic acid with iodine and methoxy group)
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane
Odor Odorless or very faint odor (common for such aromatic compounds)
Name 5-methoxy-2-iodobenzoic acid
Chemical Formula C8H7IO3
Molar Mass 280.044 g/mol
Appearance Solid (usually white to off - white)
Melting Point 147 - 149 °C
Solubility In Water Poorly soluble
Solubility In Organic Solvents Soluble in some organic solvents like ethanol, dichloromethane
Pka Around 3 - 4 (approximate value for benzoic acid derivative)
Stability Stable under normal conditions, but sensitive to strong reducing agents and bases
Packing & Storage
Packing 5 - methoxy - 2 - iodobenzoic Acid, 100g, packaged in a sealed, chemical - resistant bottle.
Storage 5 - Methoxy - 2 - iodobenzoic acid should be stored in a cool, dry place away from heat sources and direct sunlight. Keep it in a well - sealed container to prevent moisture absorption and contact with air, which could potentially lead to degradation. Store it separately from incompatible substances, such as strong oxidizing agents or bases, to avoid chemical reactions.
Shipping 5 - Methoxy - 2 - iodobenzoic acid is shipped in sealed, corrosion - resistant containers. These are carefully packaged to prevent breakage. Shipments follow strict chemical transportation regulations to ensure safety during transit.
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5-methoxy-2-iodobenzoic Acid 5-methoxy-2-iodobenzoic Acid 5-methoxy-2-iodobenzoic Acid
General Information
Frequently Asked Questions
What is the main use of 5-methoxy-2-iodobenzoic acid?
5-Amino-2-mercaptobenzoic acid is an important organic compound with critical uses in many fields.
In the field of medicinal chemistry, it plays an extremely important role. Due to its unique chemical structure, it can be used as a key intermediate for the synthesis of many biologically active drug molecules. For example, some drugs with antibacterial and anti-inflammatory properties, during the synthesis process, 5-amino-2-mercaptobenzoic acid can be ingeniously integrated into the drug molecular structure through specific chemical reactions, thus endowing the drug with unique pharmacological activity and helping the human body fight diseases.
In the field of materials science, it also has outstanding performance. Can be used to prepare polymer materials with unique functions. Using it as a raw material, through a series of processes such as polymerization, polymers with special optical, electrical or mechanical properties can be obtained. These polymers show potential application value in optoelectronic devices, such as organic Light Emitting Diodes (OLEDs), solar cells, etc. In OLEDs, such materials may improve luminous efficiency and stability, and enhance display effect.
Furthermore, in the field of dye chemistry, 5-amino-2-mercaptobenzoic acid is also indispensable. It can be used as an important starting material for the synthesis of new dyes. Using its amino and thiol reactivity, dye molecules with diverse structures can be constructed. These dyes may have excellent dyeing properties, such as high color fastness, bright color, etc., and are widely used in textiles, printing and dyeing and other industries to add brilliant colors to fabrics.
5-Amino-2-mercaptobenzoic acid plays an important role in many fields such as medicine, materials, and dyes due to its unique chemical structure and reactivity, providing a key material foundation and technical support for the development of various fields.
What are the physical properties of 5-methoxy-2-iodobenzoic acid?
5-Amino-2-chlorobenzoic acid is an organic compound, and its physical properties are quite unique. Although there is no direct record in ancient books, with today's scientific knowledge, it is described in ancient Ya Chinese as follows:
This substance is mostly white to light yellow crystalline powder under normal conditions. Looking at its color, the pure one is white and translucent. If it contains a little impurities, it will be slightly dyed light yellow, just like the state of morning light. Touch it, the texture is delicate, like powder like powder, gently ground at the fingertips, like fine sand flowing out, without a rough feeling.
Its melting point is quite critical, about 200-204 degrees Celsius. When heated gradually to this temperature, the original solid body begins to slowly melt, like ice in warm spring, gradually turning into a liquid. This melting point characteristic is like the nature of a thing, which can be used to identify the authenticity of its purity.
Furthermore, its solubility also has characteristics. In water, it dissolves quite slightly, just like a Xizi frowning, only a little gentle, and it is difficult to blend with water and milk; however, in organic solvents, such as ethanol, acetone, etc., it can dissolve well, just like a wanderer returning home, finding a suitable place and blending freely. This difference in solubility is very useful in the art of separation and purification.
And its smell, light and slightly pungent, not as rich as the aroma, nor as pungent as the stench, smell it, like being in a secluded medicine garden, a little spicy smell lingers, but it is not very strong, and it will not be boring if you smell it for a long time.
5-Amino-2-chlorobenzoic acid, with its physical properties, is important in the process of organic synthesis, or as a starting material, or as a reaction intermediate, and is indispensable in today's chemical process.
What is the synthesis method of 5-methoxy-2-iodobenzoic acid?
To prepare 5-amino-2-bromobenzoic acid, the following ancient method can be used.
First take benzoic acid as the starting material, and introduce bromine atoms by bromination method. In a suitable reaction vessel, add an appropriate amount of benzoic acid, use glacial acetic acid as the solvent, slowly add bromine, and use iron powder or iron tribromide as the catalyst. Heating makes the reaction proceed smoothly, and 2-bromobenzoic acid can be obtained in this step. The reason for the reaction is that the hydrogen atom on the benzene ring, due to the positioning effect of the carboxyl group, the bromine atom selects the adjacent position.
After obtaining 2-bromobenzoic acid, the amination step is carried out. 2-Bromo-5-nitrobenzoic acid can be obtained by mixing 2-bromobenzoic acid with concentrated sulfuric acid and concentrated nitric acid, heating to promote nitrification reaction. This is because the nitro group replaces the hydrogen atom at a specific position in the benzene ring under the action of concentrated sulfuric acid and concentrated nitric acid.
Then, the nitro group in 2-bromo-5-nitrobenzoic acid is converted into an amino group with a reducing agent. The combination of commonly selected iron powder and hydrochloric acid is used as a reducing agent and reacts at a suitable temperature. Iron powder interacts with hydrochloric acid to produce new hydrogen, and then the nitro group is gradually reduced to an amino group, and finally 5-amino-2-bromobenzoic acid is obtained.
Each step of the reaction needs to pay attention to the control of the reaction conditions, such as temperature, reactant ratio and reaction time. If the temperature is too high during bromination, it is feared that polybrominated by-products will be generated; during nitration, precise temperature control is also required to prevent the introduction of nitro groups into the position deviation or excessive nitrification; in the reduction step, the amount of reducing agent and reaction temperature also affect the purity and yield of the product. In this way, following this series of steps, 5-amino-2-bromobenzoic acid can be obtained.
What are the precautions for storing 5-methoxy-2-iodobenzoic acid?
5-Amino-2-carboxyphenylacetic acid, when hiding, all kinds of things should be paid attention to. This medicine needs to be placed in a dry, cool and well-ventilated place to prevent moisture, hot topics and sun exposure. Cover moisture can easily cause it to deteriorate, hot topics or light can cause its chemical changes and damage its effectiveness.
Furthermore, when isolated from other things and hidden. Do not store with strong oxidants, strong acids, strong bases, etc. Because of its chemical activity, encountering such things, or a violent reaction, causing safety problems, and also damaging its quality.
Storage devices also need to be carefully selected. A sealed container should be used to block air and moisture from entering. Bottles and jars made of glass or plastic should be used as appropriate, but they must ensure their chemical stability and do not react with 5-amino-2-carboxyphenylacetic acid.
In addition, there should be a clear logo at the hiding place, stating its name, characteristics, hiding methods and things to pay attention to, so as to access and manage it, so as to avoid the risk of mistaken recognition and misuse. And it needs to be checked regularly to see if there are any changes in its properties, such as color change, different taste, deliquescence, etc. If so, it should be discarded and reused to ensure the safety and efficacy of the drug.
What is the market price of 5-methoxy-2-iodobenzoic acid?
5-Amino-2-chlorobenzoic acid, which is in the market, its price varies depending on quality, quantity and market conditions.
If it is of high quality, its preparation is fine, impurities are rare, and it is very popular in the fields of high-end chemical synthesis and pharmaceutical research and development. Its price is not cheap. Usually the price per gram can reach tens of gold. Due to the complicated preparation process, the required raw materials are also rare, and the strict requirements for the environment and equipment, it is expensive and expensive.
And the amount is also related to the price. If it is purchased in bulk, due to the benefit of scale, the supplier may make a concession, and the price per gram may be slightly lower than that of retail. If you buy more than 100 grams in bulk, the price per gram may be reduced to about 20 gold.
Furthermore, changes in market conditions are also a major factor. When market supply and demand offset, the price may be stable; if demand exceeds supply, such as pharmaceutical companies developing new drugs, the demand for this material will increase sharply, and the price may rise; on the contrary, if supply exceeds demand, the producer will sell the goods, or reduce the price to sell.
In addition, its origin also has a bearing on the price. Those originating from places with advanced technology and abundant resources may have slightly lower prices than others due to cost control. However, the price difference between various places is only a few gold.
Overall, the market price of 5-amino-2-chlorobenzoic acid ranges from more than ten gold per gram to more than tens of gold. It is difficult to generalize, and it needs to be measured according to the specific situation.