As a leading (5R)-3-(3-Fluoro-4-Iodophenyl)-5-(Hydroxymethyl)-1,3-Oxazolidin-2-One supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of (5r) -3- (3-fluoro-4-iodophenyl) -5- (hydroxymethyl) -1,3-oxazolidin-2-one?
The chemical structure of (5r) -3- (3-fluoro-4-iodophenyl) -5- (hydroxymethyl) -1,3-oxazolidine-2-one is an important content in the field of organic chemistry. This compound is constructed from specific atoms according to a specific connection method.
Looking at its structure, the core is a five-membered heterocycle of 1,3-oxazolidine-2-one. In this heterocycle, nitrogen, oxygen and carbon atoms together form a ring system. In the third position of the five-membered ring, there are (3-fluoro-4-iodophenyl) groups connected. On the phenyl group, fluorine atoms and iodine atoms occupy the 3rd and 4th positions respectively. And in the 5th position of the five-membered ring, hydroxymethyl groups are connected. Among them, carbon atoms are connected with hydroxyl and methyl groups, showing a unique spatial structure.
Furthermore, the (5r) label indicates that this compound has a specific stereochemical configuration, implying that its molecules have a specific orientation and arrangement in space. This structure endows the compound with specific physical and chemical properties, which may have potential uses and values in organic synthesis, drug development and other fields. Its unique atomic arrangement and connection mode provide an important basis for exploring the reactivity and biological activity of compounds.
What are the main uses of (5r) -3- (3-fluoro-4-iodophenyl) -5- (hydroxymethyl) -1,3-oxazolidin-2-one?
(5R) -3- (3-fluoro-4-iodophenyl) -5- (hydroxymethyl) -1,3-oxazolidine-2-one, which is very important in the field of medicinal chemistry.
First, in the process of drug development, it can be a key intermediate. Because of its unique structure, it contains atoms such as fluorine and iodine, and fluorine atoms can change the lipid solubility and metabolic stability of compounds; iodine atoms have great potential in the field of radiopharmaceutical labeling. With this intermediate, drug molecules with specific biological activities can be prepared through a series of reactions, such as anti-cancer drugs. It may be able to precisely act on specific targets of cancer cells, blocking the proliferation signaling pathway of cancer cells and inhibiting their growth by means of its unique chemical structure.
Second, it is also a useful building block in the field of organic synthesis. Chemists can perform various reactions according to the organic reaction mechanism, such as nucleophilic substitution, coupling reaction, etc. With nucleophilic substitution, different substituents can be introduced into the hydroxymethyl group, expanding the structural diversity of compounds, creating new organic compounds, and providing a new material basis for materials science, total synthesis of natural products and other fields.
Third, it is also valuable in biological activity research. Because its structure is similar to some biologically active molecules, or it can interact with specific receptors, enzymes, etc., researchers can use experimental means to explore its binding mode and activity with biological macromolecules, providing ideas and data support for new drug discovery and lead compound optimization.
What are the synthesis methods of (5r) -3- (3-fluoro-4-iodophenyl) -5- (hydroxymethyl) -1,3-oxazolidin-2-one?
To prepare (5r) -3- (3-fluoro-4-iodophenyl) -5- (hydroxymethyl) -1,3-oxazolidine-2-one, the synthesis method can have the following numbers.
First, the target molecular structure can be gradually constructed through a series of organic reactions with suitable starting materials. First, an aromatic compound containing fluorine and iodine is taken and reacted with a compound with a specific functional group to introduce key substituents. For example, 3-fluoro-4-iodoaniline is selected and reacted with an appropriate carbonyl compound to construct the parent nuclear structure of oxazolidinone through condensation and other steps. This process requires fine regulation of reaction conditions, such as temperature, pH, reaction time, etc., in order to proceed in the desired direction.
Second, chiral auxiliaries can be considered to participate in the reaction to obtain products of a specific configuration. Chiral auxiliaries can guide the reaction to selectively form (5r) configurations. In the initial stage of the reaction, chiral auxiliaries are combined with starting materials, and their chiral environment is used to induce the formation of newly formed chemical bonds in a specific stereochemical direction in subsequent reactions. When the reaction reaches a certain stage, the chiral additives are removed in a timely manner to obtain the target product. This method requires strict requirements for the selection of chiral additives and the control of reaction conditions, and requires careful study to be successful.
Third, the method of catalytic reaction can also be used. The selection of specific catalysts can accelerate the reaction process and play an important role in the selectivity and stereochemical control of the reaction. Such as metal catalysts or enzyme catalysts, metal catalysts can affect the reaction path and stereochemical results by forming a specific coordination structure with the substrate; enzyme catalysts, with their unique active centers and stereospecific specificity, efficiently and selectively catalyze to generate the target product. However, the selection of suitable catalysts and the optimization of catalytic conditions are the key to this method.
What are the physicochemical properties of (5r) -3- (3-fluoro-4-iodophenyl) -5- (hydroxymethyl) -1,3-oxazolidin-2-one?
(5R) -3- (3-fluoro-4-iodophenyl) -5- (hydroxymethyl) -1,3-oxazolidine-2-one, this is an organic compound. Its physical and chemical properties are unique, let me tell you in detail.
Looking at its physical properties, under normal circumstances, this compound may be in a solid state. Because the molecular structure contains many groups, the intermolecular forces are quite complex, so it tends to form a solid state. Its melting point and boiling point are also affected by the molecular structure. Aromatic rings, fluorine atoms, iodine atoms and hydroxymethyl groups all contribute to its physical properties. The aromatic ring and the halogen atom can enhance the intermolecular force, making the melting point and boiling point relatively high; while the hydroxymethyl group can form hydrogen bonds, which further affects the melting boiling point.
As for the chemical properties, the oxazolidinone ring in this compound has certain reactivity. The carbonyl group on the ring can participate in nucleophilic addition reactions, such as reacting with nucleophilic reagents containing active hydrogen, and then form new compounds. The nitrogen atom on the ring also has lone pair electrons, which can be used as nucleophilic centers and participate in nucleophilic substitution and other reactions.
Furthermore, the substituent of 3-fluoro-4-iodophenyl gives this compound unique chemical properties. Fluorine atoms have high electronegativity, which can affect the distribution of molecular electron clouds by induction effect, reduce the density of benzene ring electron clouds, and change the activity of benzene ring electrophilic substitution reaction. Although iodine atoms have a large atomic radius, they can be used as leaving groups to participate in the substitution reaction under specific reaction conditions, and a variety of new compounds can be derived. The presence of
5 - (hydroxymethyl) also adds luster to the chemical properties of this compound. Hydroxymethyl can be oxidized and converted into aldehyde or carboxyl groups; it can also participate in esterification reactions and react with organic acids or inorganic acids to form corresponding ester compounds.
What is the market price of (5r) -3- (3-fluoro-4-iodophenyl) -5- (hydroxymethyl) -1,3-oxazolidin-2-one?
Wuwei Wen (5r) -3- (3-fluoro-4-iodophenyl) -5- (hydroxymethyl) -1,3-oxazolidine-2-one is priced on the market. This compound is not commonly available, and its synthesis may require delicate techniques and specific raw materials.
In the field of chemical trading, its price often depends on multiple factors. The first one is the difficulty of synthesis. If the synthesis requires complicated steps, harsh conditions, or rare reagents, the price will be high. If you use rare catalysts or go through multiple steps, each step affects the cost and causes the price to rise.
Furthermore, market supply and demand also determine its price. If there is a sudden increase in demand for a certain field in many industries and the supply is limited, the price will rise. On the contrary, if there is little demand and the supply exceeds the demand, the price may drop.
However, I have searched all over the books and market records, but I have not obtained the exact price of this particular compound. Or because there are few people involved in the trading of this compound, or because there are many transactions, it is done privately and has not been made public.
To know the exact price, you can consult a chemical raw material supplier, or seek it on a professional chemical trading platform, or consult a merchant specializing in organic compound trading, and you can get a more accurate price.
