(5r)-3-(3-fluoro-4-iodophenyl)-5-hydroxymethyl-2-oxazolidinone

(5R) -3- (3-fluoro-4-iodophenyl) -5-hydroxymethyl-2-oxazolidinone has a wide range of uses. In the field of medicine, it is often used as a key intermediate to create various drugs. Gein oxazolidinone compounds have unique structures and show good biological activities in antibacterial, antitumor and many other aspects. ( 5R) - 3- (3-fluoro-4-iodophenyl) - 5-hydroxymethyl-2-oxazolidinone can be modified by specific chemical reactions to obtain antibacterial drugs with stronger antibacterial ability, which is of great significance for the treatment of various drug-resistant bacterial infections.
In the field of organic synthesis, it is also an important raw material. Because its structure contains multiple reactive functional groups, such as hydroxymethyl, oxazolidinone rings, etc., it can participate in many organic reactions, such as nucleophilic substitution, redox, etc., to construct more complex organic molecular structures, laying the foundation for the research and development of new organic materials. In addition, in chemical research, as a special structural compound, it provides an effective model for studying intermolecular interactions and reaction mechanisms, and helps researchers to explore chemical laws in depth, expand the boundaries of chemical cognition, and contribute significantly to the development of organic chemistry, medicinal chemistry, and other disciplines.

To prepare (5r) -3- (3-fluoro-4-iodophenyl) -5-hydroxymethyl-2-oxazolidinone, there are several common methods.
First, the oxazolidinone ring can be constructed from a suitable starting material through a multi-step reaction. If an amino acid derivative containing a suitable substituent is selected, the ring is formed by condensation reaction. First, the key functional groups are protected with protective groups to prevent unnecessary side reactions in the reaction. Then the fluorine-containing aryl halide with iodine is coupled to a specific position through a metal-catalyzed coupling reaction, such as a palladium-catalyzed coupling. The subsequent steps carefully remove the protective group to obtain the target product. This process requires fine regulation of reaction conditions, such as temperature, solvent, catalyst dosage, etc., to ensure that the reaction proceeds smoothly and has high selectivity.
Second, it can also be based on cyclization. First prepare chain-like precursors with suitable functional groups, such as compounds containing hydroxyl groups, amino groups and carbonyl groups. Under suitable reagents and conditions, cyclization occurs in the molecule to form oxazolidinone structures. Subsequently, fluorine and iodine atoms are introduced into specific positions in the aromatic ring by means of halogenation reactions. This path requires careful control of the sequence and conditions of each step of the reaction to obtain products with higher yield and purity.
When preparing this compound, it is crucial for the separation and identification of reaction intermediates. It is often used by techniques such as column chromatography, nuclear magnetic resonance, mass spectrometry, etc., to ensure the correctness of each step of the product, and finally (5r) -3- (3-fluoro-4-iodophenyl) -5-hydroxymethyl-2-oxazolidinone is successfully prepared.

(5R) - 3- (3-fluoro-4-iodophenyl) - 5-hydroxymethyl-2-oxazolidinone is an organic compound. Its physical and chemical properties are quite important, as follows:
First appearance, this compound is often white to white solid, fine texture, like the first snow in winter, clean and pleasing to the eye.
As for the melting point, it is within a specific temperature range, which is the critical temperature for it to change from solid to liquid. When heated to this temperature range, the intermolecular forces gradually weaken, the lattice structure begins to change, and it turns into a flowing liquid state.
In terms of solubility, it exhibits unique solubility properties in common organic solvents. In some organic solvents such as dichloromethane, N, N-dimethylformamide, it has good solubility and can be uniformly dispersed, just like fish entering water, and the phase is fused infinitely. However, in water, the solubility is very small, just like oil floating in water, and it is distinct. This property is closely related to the polarity of the molecule, and its molecular structure makes it have different affinities to different polar solvents.
Furthermore, its chemical stability is also an important property. Under normal temperature and pressure and general environmental conditions, the compound is relatively stable and the molecular structure is not easy to change. However, in case of extreme conditions such as strong acid, strong base or high temperature, strong oxidant, the chemical bonds in the molecule will be easily affected, chemical reactions will occur, resulting in molecular structure changes, and new compounds will be formed.
In addition, the spectral properties of this compound also have characteristics. In the infrared spectrum, specific functional groups will generate absorption peaks at the corresponding wave numbers, which can be used to identify the functional groups contained in the molecule, such as hydroxyl, carbonyl, etc. have their own unique absorption peaks, which are like human fingerprints and unique, providing a strong basis for identifying the compound.

Today I have a question, what is the market price of (5r) -3- (3-fluoro-4-iodophenyl) -5-hydroxymethyl-2-oxazolidinone. However, I have checked the books all over, but I have not obtained the exact price of this substance in the market. This substance may be a special organic compound, or used in specific scientific research and pharmaceutical fields. Its price is often affected by a variety of reasons.
First, the cost of raw materials. If the raw materials required to synthesize this compound are scarce or difficult to prepare, the price will be high, and the final product price will not be low.
Second, the difficulty of synthesis. If the synthesis steps are complicated, many reaction processes are required, and the reaction conditions are strict, such as precise temperature, pressure, catalyst, etc., the synthesis cost will increase and the price will be high.
Third, market demand. If the compound is in high demand in scientific research or industry, but the supply is limited, the price will rise according to the reason of supply and demand; conversely, the demand is weak, and the price may stabilize or decrease.
Fourth, the scale of production. In large-scale production, due to the scale effect, the unit cost may be reduced, and the price may also be favorable; in small-scale production, the cost is higher and the price is also higher.
Therefore, in order to determine the price of (5r) -3- (3-fluoro-4-iodophenyl) -5-hydroxymethyl-2-oxazolidinone in the market, it is necessary to consider the raw materials, synthesis, supply and demand, scale and other factors in detail, and it is advisable to consult professional chemical product suppliers and scientific research reagent sales institutions to obtain more accurate price information.

(5R) - 3 - (3 - fluoro - 4 - iodophenyl) - 5 - hydroxymethyl - 2 - oxazolidinone needs to be carefully examined for its safety.
The properties of the chemical products are complex and changeable, or they are hidden from people and are not easy to observe. (5R) - 3 - (3 - fluoro - 4 - iodophenyl) - 5 - hydroxymethyl - 2 - oxazolidinone, in its molecular structure, the atoms of fluorine and iodine are among them. Fluorine is common in many chemical products, but its activity is quite strong, or it reacts with surrounding substances, causing unpredictable changes. The same is true of iodine, its chemical properties are active, and under specific conditions, it may lead to the modification of molecular structure, which may be related to its safety.
Furthermore, the structure of oxazolidinone is common in the field of organic synthesis, but its ring structure may have a certain reactivity. The existence of 5-hydroxymethyl makes the molecule more hydrophilic, or makes its metabolic pathway in the organism unique. When this substance enters the organism, it may interact with macromolecules such as proteins and nucleic acids, or change its conformation, or disturb its function, thus endangering the health of the organism.
From an environmental perspective, if (5r) -3- (3-fluoro-4-iodophenyl) -5-hydroxymethyl-2-oxazolidinone accidentally flows into nature, its fluorine and iodine-containing characteristics may be difficult to degrade in the environment, which will accumulate for a long time, or cause environmental pollution and cause ecological harm. Therefore, its safety, whether in the organism or in the external environment, needs to be scientifically studied, and its advantages and disadvantages can be clarified.