6 Bromo 3 Iodo 2 Methylpyridine

6-Bromo-3-iodine-2-methylpyridine is one of the organic compounds. Its main uses are quite extensive, and it is often used as a key intermediate in the field of organic synthesis.
Geinpyridine ring has a unique electronic structure and reactivity, and the substituents such as bromine, iodine and methyl give it specific reactivity. In the field of pharmaceutical chemistry, it can be converted into molecules with specific biological activities or potential drug lead compounds through a series of reactions. For example, by coupling reactions with other reagents containing specific functional groups, complex drug molecular frameworks can be constructed to explore new drugs with antibacterial and anti-tumor effects.
In the field of materials science, there is also a place for it. After chemical modification, materials with specific photoelectric properties can be prepared. For example, by linking with conjugated systems, it is expected to develop new functional materials for organic Light Emitting Diodes (OLEDs) or solar cells to improve the properties of charge transport and luminous efficiency of materials.
In addition, in the field of pesticide chemistry, it may be derived from new pesticide ingredients. With the mechanism of action against specific biological targets and rational molecular design, high-efficiency, low-toxicity and environmentally friendly pesticides can be created to help control agricultural pests and diseases.
In conclusion, 6-bromo-3-iodine-2-methylpyridine has important potential value in many chemically related fields, providing a key material basis and research direction for organic synthesis, drug research and development, material preparation, and pesticide creation.

The synthesis method of 6-bromo-3-iodine-2-methylpyridine covers a variety of pathways, each of which has its own reasons, and is described in detail as follows.
First, 2-methylpyridine is used as the starting material. First, it reacts with bromine, which is a process of electrophilic substitution. Due to the electronic effect of the nitrogen atom on the pyridine ring, the 3 and 5 positions of 2-methylpyridine are relatively more electrophilic. Under this reaction condition, the bromine atom is selectively substituted in the 3 position to generate 3-bromo-2-methylpyridine. Subsequently, the resulting product is reacted with an iodine source under specific conditions, so that the iodine atom replaces the hydrogen atom at the 6 position to obtain 6-bromo-3-iodine-2-methylpyridine. This route step is relatively simple, and the raw materials are relatively common and easy to obtain. However, the precise control of the reaction conditions is crucial, otherwise it is prone to side reactions, which will affect the purity and yield of the product.
Second, you can start from pyridine. Methyl is introduced first, and usually a suitable methylating agent, such as iodomethane, is reacted with pyridine under basic conditions to generate 2-methylpyridine. After that, as described earlier, bromination and iodization are carried out in sequence to achieve the target product. Although the starting material of this path is more basic and common, there are more steps, and each step of the reaction needs to be properly handled to ensure the smooth progress of the overall synthesis, and the optimization of the conditions of each step of the reaction also needs to be carefully considered.
Third, the coupling reaction strategy using transition metal catalysis. Appropriate halogenated pyridine derivatives can be selected with suitable leaving groups, such as bromine, iodine, etc. Under the action of transition metal catalysts, such as palladium catalysts, the coupling reaction occurs with the corresponding organometallic reagents. Although this method can construct the target molecular structure more accurately, the catalyst cost is higher, the reaction conditions are also more demanding, and the reaction equipment and operation technology are quite strict, and the separation and recovery of the catalyst after the reaction are also issues to be considered.
In short, there are many methods for synthesizing 6-bromo-3-iodine-2-methyl pyridine. In practical applications, it is necessary to carefully select the appropriate synthesis route according to the specific experimental conditions, raw material availability, cost considerations, and product purity and yield requirements.

6-Bromo-3-iodine-2-methylpyridine is one of the organic compounds. Its physical properties are very important, which is related to its application in many fields.
First of all, its appearance, at room temperature, the compound is mostly solid or crystalline, the appearance color is usually white to light yellow, and the texture is fine. This appearance feature can help chemists to initially identify in experiments.
and melting point, after precise determination, its melting point is within a specific temperature range, which is of great significance for the purification, identification and subsequent processing of the compound. Knowing the melting point, chemists can precisely control the reaction conditions to achieve the desired experimental effect.
Furthermore, the boiling point of this compound also has a specific value, and the boiling point reflects the temperature at which it changes from liquid to gaseous under a specific pressure. This property is crucial in separation and purification operations such as distillation, and it can be effectively separated from the mixture according to the difference in boiling point.
Solubility is also a key physical property. 6-Bromo-3-iodine-2-methyl pyridine exhibits some solubility in organic solvents, such as common ethanol, ether, etc., while its solubility in water is relatively limited. This difference in solubility allows chemists to choose suitable solvents for reactions, extractions, and other operations.
In addition, the density of the compound is also a specific value, and the density data is indispensable in solution preparation, material balance, etc., which can help experimenters accurately measure and operate.
The physical properties of 6-bromo-3-iodine-2-methylpyridine, such as appearance, melting point, boiling point, solubility and density, play an important role in many fields such as organic synthesis, drug development, materials science, etc., laying a solid foundation for chemists to further study and rationally apply this compound.

6-Bromo-3-iodine-2-methylpyridine is one of the organic compounds. Its chemical properties are unique, including bromine, iodine, methyl and pyridine rings in its molecular structure.
The first word is nucleophilic substitution reaction. Because bromine and iodine are halogen atoms, they have certain activity. Under appropriate conditions, they can be attacked by nucleophiles, and halogen atoms can leave to form new compounds. For example, using alkoxides as nucleophiles, nucleophilic substitution can occur, and halogens are replaced by alkoxy groups. This reaction is often used in organic synthesis to construct ether structures.
On redox reactions. Pyridine rings can participate in redox processes. Under the action of appropriate oxidants, the pyridine ring can be oxidized, changing its electron cloud distribution and chemical activity. Conversely, when encountering a reducing agent, the pyridine ring may also obtain electrons and be reduced to form hydrogenated pyridine derivatives. This change has a great impact on the physical and chemical properties of the compound.
In addition, the presence of methyl groups also affects. Methyl groups are the power supply group, which can increase the electron cloud density of the pyridine ring and affect the activity and selectivity of the substitution reaction on the ring. If the electrophilic substitution reaction occurs, the density of the adjacent and para-potential electron clouds of methyl groups is relatively high, and the electrophilic reagents are more likely to attack this position. Compared with the pyridine without methyl, the reaction activity and check point selection are different.
At the same time, the different electronegativity of bromine and iodine makes them behave differently in chemical reactions. Generally speaking, iodine atoms are relatively large and slightly less electronegative than bromine, so iodine is more likely to leave. In some nucleophilic substitution or elimination reactions, iodine atoms may have higher reactivity.
In conclusion, 6-bromo-3-iodine-2-methyl pyridine is rich in chemical properties. In the field of organic synthesis, with its diverse reactivity, it can be used as a key intermediate for the preparation of various complex organic compounds.

I have been searching for the books of all kinds of things in the market, but I have not been able to find the exact price of 6-bromo-3-iodo-2-methylpyridine. This compound may have little circulation in the market due to its special use and lack of demand, so the price is difficult to find.
If you want to measure its price, you can refer to the price of similar substances to deduce. The price of chemical substances often depends on the difficulty of preparation, the rarity of raw materials, and the amount of demand. If the preparation is complex and the raw materials are rare, the price will be high; if the preparation is easy, the raw materials are wide, and the demand is large, the price will be flat.
6-bromo-3-iodo-2-methylpyridine contains halogen atoms such as bromine and iodine. The synthesis may require special methods and precious materials, and the preparation is not easy. And pyridine derivatives are often key intermediaries in the pharmaceutical, pesticide, material and other industries. If so, its preparation is difficult, its use is important, or the price is high.
However, due to the lack of circulation in the market, there is no public price. To know the price, you can consult chemical reagent manufacturers, raw material suppliers, or companies involved in the production of this chemical. Because they are in this business, they know the price, and they should be more sure.