6 Chloro 2 Iodo 7h Purine
Iodobenzene

6 Chloro 2 Iodo 7h Purine

Fengxi Chemical

Specifications

HS Code

210200

Name 6-chloro-2-iodo-7H-purine
Molecular Formula C5H2ClIN4
Molecular Weight 296.45 g/mol
Appearance Solid (predicted)
Melting Point No data available
Boiling Point No data available
Solubility No data available
Density No data available
Pka No data available
Logp No data available
Cas Number No data available
Name 6-chloro-2-iodo-7H-purine
Chemical Formula C5H2ClIN4
Molar Mass 296.45 g/mol
Appearance Solid (predicted, actual may vary)
Melting Point No common data found (needs experimental determination)
Boiling Point No common data found (needs experimental determination)
Solubility In Water Low (due to non - polar nature of purine ring and halogen atoms)
Solubility In Organic Solvents Soluble in some organic solvents like dichloromethane, chloroform (predicted based on similar compounds)
Density No common data found (needs experimental determination)
Pka No common data found (needs experimental determination)
Stability Stable under normal conditions but may react with strong oxidizing or reducing agents
Reactivity Can participate in substitution reactions due to the presence of halogen atoms
Chemical Formula C5H2ClIN4
Molar Mass 296.45 g/mol
Appearance Solid (predicted, no common color reported)
Melting Point No data available
Boiling Point No data available
Solubility In Water Low solubility (predicted, as it's a heterocyclic aromatic compound)
Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO (predicted)
Density No data available
Pka No data available
Reactivity Can participate in substitution reactions due to presence of halogen atoms
Chemical Formula C5H2ClIN4
Molar Mass 308.45 g/mol
Appearance Solid (likely, based on similar heterocyclic compounds)
Solubility In Water Low (due to the hydrophobic nature of the purine ring and halogen atoms)
Solubility In Organic Solvents Moderate solubility in polar organic solvents like DMSO, DMF
Stability Stable under normal conditions, but sensitive to light and strong oxidizing agents
Packing & Storage
Packing 100g of 6 - chloro - 2 - iodo - 7H - purine in a sealed, labeled chemical - grade container.
Storage 6 - chloro - 2 - iodo - 7H - purine should be stored in a cool, dry place, away from direct sunlight. Keep it in a tightly - sealed container to prevent exposure to moisture and air, which could potentially lead to chemical degradation. Store it separately from incompatible substances, such as strong oxidizers and bases, to avoid unwanted reactions.
Shipping 6 - chloro - 2 - iodo - 7H - purine is shipped in sealed, specialized containers to prevent leakage. These are transported under strict regulations, ensuring safe handling due to its chemical nature.
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6-chloro-2-iodo-7h-purine 6-chloro-2-iodo-7h-purine 6-chloro-2-iodo-7h-purine
General Information
Frequently Asked Questions
What is the chemistry of 6-chloro-2-iodo-7h-purine?
6-Chloro-2-iodine-7H-purine, an organic compound, contains chlorine, iodine and other halogen atoms and the core structure of purines. Its chemical properties are unique, and it is a key substance for various chemical and biological research.
When it comes to physical properties, it is mostly solid under normal conditions, and the melting point and boiling point vary depending on the intermolecular forces. Its solubility is related to molecular polarity, and its solubility in polar solvents is better than that in non-polar solvents.
Chemically, halogen atoms are active, and chlorine and iodine can participate in many reactions. In the nucleophilic substitution reaction, halogen atoms are easily replaced by nucleophilic reagents, such as reacting with hydroxyl and amino reagents to form new derivatives, which is an important path for the synthesis of various purine compounds.
Due to the purine structure, 6-chloro-2-iodine-7H-purine also has the commonality of purine compounds. Under specific conditions, reactions such as ring substitution and addition can occur, which are of great significance for the construction of complex molecular structures. In the field of biology, purine compounds are often involved in important physiological processes such as nucleic acid synthesis. The presence of 6-chloro-2-iodine-7H-purine or halogen atoms affects related biological activities. They can be used as potential lead compounds in drug research and development, and are modified and optimized to obtain drugs with specific biological activities.
Its rich chemical properties have potential application value in organic synthesis, pharmaceutical chemistry, biochemistry and other fields. It is an object of in-depth exploration by researchers. It is expected to expand its application in various fields and promote scientific progress through research.
What are 6-chloro-2-iodo-7h-purine synthesis methods?
The synthesis method of 6-chloro-2-iodine-7H-purine is an important matter in the field of chemistry. In the past, to make this substance, the classical organic synthesis was often followed.
One method uses the purine parent as the starting material. Introduce chlorine atoms at a specific position in the purine ring first, which can be achieved by halogenation reaction. Select a suitable halogenation reagent, such as a chlorine-containing halogen, and under specific reaction conditions, make the chlorine atom replace the corresponding hydrogen atom in the purine ring. This step requires fine regulation of the reaction temperature, time and the ratio of the reactant to ensure the precise positioning of the chlorine atom.
Next, introduce iodine atoms. Commonly used iodine substitution reagents are selected to adapt the reaction conditions according to the modified characteristics of the purine ring. Or use nucleophilic substitution reaction to make iodine ions interact with the chlorinated purine intermediates. This step also requires attention to the reaction environment, such as solvent properties, catalyst presence or absence, etc., all of which have a great impact on the effectiveness of the iodine substitution reaction.
Another approach is to start from simple compounds and construct purine rings through multi-step reactions. Small molecules containing specific substituents are prepared first, and then a purine skeleton is constructed through cyclization reaction, and chlorine and iodine atoms are introduced at the same time. Although this strategy is complicated in steps, it has unique advantages for precise control of substituent positions and reaction processes. During the reaction process, every step needs to be strictly monitored and optimized to improve the purity and yield of the product. All these methods are feasible ways to synthesize 6-chloro-2-iodine-7H-purine.
6-chloro-2-iodo-7h-purine in what areas
6-Chloro-2-iodine-7H-purine, this is a special chemical substance. It has extraordinary uses in many fields.
In the field of pharmaceutical research and development, this compound has potential medicinal value. Because purines are often associated with many key biochemical processes in organisms, the unique structure of 6-chloro-2-iodine-7H-purines may enable them to exhibit effects on specific biological targets. For example, in the development of anti-cancer drugs, purine analogs are often investigated because they may interfere with the nucleic acid synthesis process of cancer cells, thereby inhibiting the proliferation of cancer cells. 6-Chloro-2-iodine-7H-purine has unique chlorine and iodine substituents, or endows it with unique biological activities, providing a novel direction for the creation of anti-cancer drugs.
In the field of organic synthetic chemistry, 6-chloro-2-iodine-7H-purine can be used as a key intermediate. With the chlorine and iodine atoms in its structure, it can be derived through various organic reactions. For example, halogen atoms can participate in nucleophilic substitution reactions, interact with various nucleophiles, and introduce different functional groups to build more complex organic molecules. Chemists can use this to synthesize materials with specific functions or develop new organic catalysts.
In the field of materials science, 6-chloro-2-iodine-7H-purine may contribute to the improvement of the properties of certain materials. If it is introduced into polymer materials, its unique electronic structure and spatial configuration may change the electrical and optical properties of the material. For example, in optoelectronic materials, specific purine derivatives can optimize the charge transport performance of the material, thereby improving the photoelectric conversion efficiency.
In summary, although 6-chloro-2-iodine-7H-purine is a niche chemical substance, it has broad application prospects in many fields such as medicine, organic synthesis and materials science, and needs to be further explored and developed by scientific researchers.
What is the market outlook for 6-chloro-2-iodo-7h-purine?
6-Chloro-2-iodine-7H-purine, this is a chemical substance. Its market prospects are multi-faceted, so let me tell you in detail.
Looking at the field of medicine, many innovative drug development often relies on such purine derivatives containing special substituents. 6-chloro-2-iodine-7H-purine has unique structures and may have antiviral and antitumor activities. Nowadays, the demand for antiviral drugs is increasing day by day, and the virus mutates frequently, so the development of new antiviral drugs is imminent. This compound may become a key intermediate, chemically modified and modified to obtain highly effective antiviral drugs, so it has great potential in the pharmaceutical research and development market.
Furthermore, in the field of organic synthesis, it serves as a special structural block, providing the possibility for the synthesis of complex organic molecules. Organic synthesis chemists are constantly looking for novel structural units to create unique molecular structures. 6-Chloro-2-iodine-7H-purine chlorine and iodine atoms can participate in various chemical reactions, such as nucleophilic substitution, coupling reactions, etc., assisting chemists in constructing organic compounds with specific functions and structures, which may have broad applications in fine chemical products and materials science-related organic synthesis.
However, its market also has challenges. Synthesis of such compounds may require complex processes and special reagents, and the cost may be high, limiting large-scale production and application. And when new compounds enter the market, they must undergo strict safety and effectiveness assessments, which is time-consuming and laborious.
Although there are challenges, with the advancement of science and technology, the synthesis process or optimization, the cost is reduced. If its biological activity and application value can be confirmed through in-depth research, 6-chloro-2-iodine-7H-purine will emerge in the fields of medicine and organic synthesis, and the market prospect is promising.
What are the precautions for the preparation of 6-chloro-2-iodo-7h-purine?
There are many precautions for the preparation of 6-chloro-2-iodine-7H-purine, which need to be handled with caution.
First, the selection of raw materials must be fine. The purity of the starting material used is crucial, and the existence of impurities often causes the reaction to be skewed and the product is impure. For example, starting purine compounds need to be purified multiple times to ensure quality before entering the next step.
Second, the control of reaction conditions needs to be accurate. A slight deviation in temperature may cause the reaction rate to change, or even lead to side reactions. This reaction is mostly carried out in specific solvents, and the properties of the solvent, such as polarity and boiling point, have a great impact on the reaction. And the pH of the reaction system also needs to be strictly regulated, often with buffers to maintain stability, in order to promote the smooth reaction.
Third, the halogenation step should be paid special attention to. When introducing chlorine and iodine atoms, the choice, dosage and order of addition of halogenated reagents are all exquisite. Such as chlorinated reagents, which are highly active and prone to over-halogenation, so they need to be added cautiously according to the reaction process. When iodizing, the activity and stability of the iodine source should also be considered to prevent iodine ions from oxidizing or incomplete reaction.
Fourth, safety protection should not be slack. The reagents used are mostly toxic, corrosive or irritating. During operation, protective equipment must be worn, and the operation should be well ventilated to prevent the inhalation of harmful gases, and the waste reagents should be properly disposed of, so as not to
Fifth, the key to monitoring and controlling the reaction process. By means of thin layer chromatography, liquid chromatography and other means, real-time monitoring can be used to know the reaction progress, adjust the conditions in a timely manner, and maintain the yield and purity of the product. If the reaction is too long or insufficient, the quality of the product will be damaged.
Preparation of 6-chloro-2-iodine-7H-purine, all links are interconnected, and the subtleties are all about success or failure. It is necessary to be rigorous and meticulous in order to achieve ideal results.