Competitive 6-Chloro-4-Iodonicotinonitrile prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615371019725 or mail to
sales7@bouling-chem.com.
We will respond to you as soon as possible.
Tel: +8615371019725
Email: sales7@bouling-chem.com
As a leading 6-Chloro-4-Iodonicotinonitrile supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemistry of 6-chloro-4-iodonicotinonitrile?
6-Chloro-4-iodoniconitrile is also an organic compound. It is active and shows a unique state in many chemical reactions.
This substance has the characteristics of halogen atoms. Chlorine and iodine are both halogen elements and have extraordinary activity. When chlorine atoms are nucleophilic substituted, other groups can be introduced into molecules. For example, when nucleophilic reagents meet 6-chloro-4-iodoniconitrile, chlorine can easily become nucleophilic groups and form new organic structures.
Iodine atoms in specific reactions, either as leaving groups, or by virtue of their large atomic radius and polarization, affect the distribution of molecular electron clouds and cause reaction activity changes. And iodine atoms can be used to construct carbon-iodine bonds, paving the way for subsequent coupling reactions, such as palladium-catalyzed cross-coupling, which can connect different carbon groups and expand the molecular structure complexity.
The nitrile group (-CN) of the nicotinitrile part has high reactivity. It can be hydrolyzed into carboxyl groups. Under appropriate conditions, under the catalysis of acids or bases, the nitrile group can be transferred to carboxyl groups to obtain carboxyl-containing derivatives, which is very important for organic synthesis of acid compounds. The nitrile group can also be reduced to an amine group. By means of hydrogenation, the three bonds in the nitrile group obtain hydrogen and become an amine group, which is a method for synthesizing nitrogen-containing organic compounds.
The spatial structure of 6-chloro-4-iodonicotinitrile affects the reaction selectivity due to the difference in atomic size and arrangement. The large atoms of chlorine and iodine occupy space, which makes the reagent close to the specific part of the molecule and is blocked by space, which determines the reaction check point and rate.
In summary, 6-chloro-4-iodonicotinitrile is an important raw material in the field of organic synthesis due to the characteristics of chlorine, iodine and nitrile groups. Organic compounds with different structures and functions can be prepared through various reactions.
What are the physical properties of 6-chloro-4-iodonicotinonitrile?
6-Chloro-4-iodonicotinitrile is one of the organic compounds. Its physical properties are as follows:
In terms of color state, it often takes the form of a solid powder similar to white to light yellow. The characteristics of this color state are easy to distinguish by the naked eye, which is one of the key points for identifying this substance.
Melting point is also an important physical property. Its melting point is within a specific range, and this value is crucial for determining its purity and thermal change. When heated to the melting point, the state of matter gradually changes from solid to liquid. Accurate determination of the temperature point of this process can provide an important basis for the study of its characteristics. In terms of solubility, it exhibits some solubility in common organic solvents such as dichloromethane and N, N-dimethylformamide (DMF). In dichloromethane, it can be partially dissolved to form a homogeneous dispersion system. This property makes dichloromethane a suitable solvent for dissolving 6-chloro-4-iodonicotinitrile in related chemical operations for subsequent reactions or analysis. In DMF, the solubility is better and it can be more fully dispersed and dissolved, which provides convenience for the use of 6-chloro-4-iodonicotinitrile in the reaction system using DMF as the solvent. However, in water, its solubility is very small, and it is difficult to form a homogeneous system with water, which is due to the large difference between the molecular structure of the compound and the polarity of water.
In addition, its density is also a specific value, although it is often not the focus of attention, but in some precise physical and chemical calculations and operations involving quantitative transfer of substances, density data are also of great significance, which is related to the accurate grasp of the relationship between its mass and volume.
What is 6-chloro-4-iodonicotinonitrile synthesis method?
6-Chloro-4-iodine nicotinitrile is also an organic compound. The method of its synthesis is described in ancient books, and it is now described by you.
First, based on nicotinitrile, halogenation is performed. The structure of nicotinitrile has a reactive check point and can interact with halogenating reagents.
In the step of chlorination, a suitable chlorinating agent, such as a compound containing chlorine, is often used, and accompanied by suitable reaction conditions. If the temperature is controlled and an appropriate solvent is selected, the chlorinating agent is contacted with nicotinitrile, and a chlorine atom is introduced at a specific position of nicotinitrile to obtain a chlorine-containing nicotinitrile intermediate.
Next, the method of iodization is carried out. The obtained intermediate containing chloronicotinitrile is added with an iodizing reagent. The choice of iodizing reagent depends on the success or failure of the reaction and the yield. In this step, it is also necessary to adjust the reaction conditions, such as temperature, pH, etc. Because the iodization reaction may require a specific environment, the iodine atom can be accurately connected to the predetermined position, that is, it is in a proper relative position with the chlorine atom, and finally 6-chloro-4-iodonicotinitrile is obtained.
In addition, during the reaction, a catalyst may be required to help to speed up the reaction process and increase its yield. The nature of the catalyst can guide the reaction, so that the reaction can proceed in the desired direction. And after the reaction is completed, there may be steps of separation and purification to remove impurities and obtain pure 6-chloro-4-iodoniconitrile. The separation method, or distillation, extraction, recrystallization, etc., depends on the nature of the product and impurities.
6-chloro-4-iodonicotinonitrile in what areas
6-Chloro-4-iodoniconitrile is an important intermediate commonly used in the field of organic synthesis. In the field of medicinal chemistry, it has a wide range of uses. Due to its special chemical structure, it can undergo various chemical reactions to construct complex compounds with biological activity to develop new drugs. For example, in the creation of anti-cancer drugs, by modifying the structure of 6-chloro-4-iodoniconitrile, molecules that have specific targeting effects on cancer cells may be obtained, which can precisely target cancer cells and reduce damage to normal cells.
In the field of materials science, it also has potential applications. It can be used as a basic unit for building functional materials. After specific polymerization reactions or modifications, materials with special optical and electrical properties can be obtained. For example, it is expected to be used in the preparation of organic Light Emitting Diode (OLED) materials, giving them unique luminescence properties and improving display effects.
Furthermore, in terms of pesticide chemistry, 6-chloro-4-iodoniconitrile can be used as a key raw material to synthesize highly efficient and low-toxicity pesticides. By ingeniously designing its chemical structure, pesticides can be highly selective to specific pests or pathogens, effectively killing pests, and reducing the harm to the environment and non-target organisms, contributing to the green and sustainable development of agriculture.
What is the market outlook for 6-chloro-4-iodonicotinonitrile?
6-Chloro-4-iodoniconitrile, this substance has a promising future in today's chemical market. It has a wide range of uses in the field of pharmaceutical and chemical industry. As far as pharmaceuticals are concerned, it is often a key intermediate that can help synthesize other types of pharmaceutical ingredients. Today's pharmaceutical development is rapid, and the demand for novel and efficient drugs is on the rise. 6-chloro-4-iodoniconitrile is not only a pharmaceutical raw material, but will attract more attention due to the rise of the pharmaceutical industry.
It also has a place in the field of pesticide chemicals. It may be used to create new pesticides to cope with the changes in pests today. In today's agriculture, there is a strong demand for high-efficiency, low-toxicity and environmentally friendly pesticides. If 6-chloro-4-iodoniconitrile can be used in this direction to produce suitable pesticide products, the market space will be broad.
However, looking at its market prospects, there are also challenges. The process of synthesizing this substance may need to be refined. If the cost is too high, it will affect its large-scale application. And the regulations of the chemical industry are becoming stricter, and the production and use of 6-chloro-4-iodoniconitrile must be in compliance. But overall, in view of the development trend of the pharmaceutical and pesticide industries, if the relevant problems can be overcome, 6-chloro-4-iodoniconitrile is expected to gain a good development opportunity in the market, occupy an important position in the chemical industry chain, and contribute to the progress of related industries.