6-Iodo-4-Quinazolone

Fengxi Chemical

Specifications

HS Code	964809
Chemical Formula	C8H5IN2O
Molecular Weight	286.04 g/mol
Appearance	Solid (usually powder)
Physical State At Room Temp	Solid
Odor	Typically odorless
Solubility In Water	Low solubility
Solubility In Organic Solvents	Soluble in some organic solvents like DMSO
Melting Point	Varies, but in a certain range
Stability	Stable under normal conditions, but may decompose on heating
Chemical Formula	C8H5IN2O
Molecular Weight	286.04
Appearance	Solid (usually powder)
Physical State At Room Temperature	Solid
Odor	Typically odorless
Solubility In Water	Poorly soluble
Solubility In Organic Solvents	Soluble in some organic solvents like DMSO
Melting Point	Data varies, around [X] °C (specify if known)
Pka Value	Data may be available depending on functional groups
Stability	Stable under normal conditions, but sensitive to light and air over time
Density	Data may vary, [X] g/cm³ (specify if known)

As an accredited 6-Iodo-4-Quinazolone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 6 - iodo - 4 - quinazolone packaged in a sealed, labeled chemical - grade bottle.
Storage	6 - iodo - 4 - quinazolone should be stored in a cool, dry place. Keep it in a tightly sealed container to prevent moisture and air exposure, which could potentially lead to chemical degradation. Store away from sources of heat and ignition. Avoid storing near incompatible substances to prevent unwanted reactions. This ensures its stability and integrity over time.
Shipping	6 - iodo - 4 - quinazolone, a chemical, is shipped with utmost care. Packed in air - tight, corrosion - resistant containers. Shipment follows strict chemical transport regulations to ensure safety during transit.

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General Information

Historical Development

6-Iodine-4-quinazolinone, its substance is also in the field of chemistry, gradually showing its traces. At the beginning, people did not know its nature, and the research was rare. However, the years passed, and the sages were unremitting, and began to explore its secrets.
In the past, researchers thought hard, trying to understand its quality. Or in the room, using various instruments, observing its changes; or seeking clues from ancient books. After several years, I finally knew that it can be used as a raw material for medicine, and it has a useable place in medicine.
Years have passed, and the research has deepened, knowing that it can help synthesize new drugs, cure diseases and save people. Its production method is also gradually refined, from simple at the beginning to exquisite later. This substance has also gradually appeared in the world since it was unknown, adding to the progress of medicine and leaving its mark on the way of historical evolution.

Product Overview

6-Iodo-4-Quinazolone is the special thing I got when I studied all kinds of chemical products. Its color is yellowish, it is crystalline, and it shimmers under the light, as if it contains endless mysteries.
The generation of this product has gone through many complex reactions. This unique thing is obtained by combining and transforming various chemical reagents in a precise ratio and at a suitable temperature in a delicate instrument.
Looking at its characteristics, it has moderate solubility in organic solvents. Its structure is unique, and the 6-position iodine atom is related to the 4-Quinazolone skeleton, giving it a different chemical activity. Or in the field of pharmaceutical research and development, it can be used as a potential lead compound to find new ways to overcome difficult diseases. Or in material science, with its characteristics, prepare new materials with specific properties. I will continue to explore, hoping to uncover more hidden wonders and add to the field of chemistry.

Physical & Chemical Properties

6-Iodo-4-Quinazolone, organic compounds are also. Its physical and chemical properties are worth exploring. Viewing its shape, at room temperature, or in a solid state, the color is white or nearly white, like crystals, with a certain crystal structure, which is caused by the orderly arrangement of molecules. Its melting and boiling point depends on the intermolecular force, and the melting point or in a specific temperature range. At this temperature, the lattice can be destroyed, causing it to change from solid to liquid. The boiling point is also related to it, reflecting the energy required for the molecule to leave the liquid phase.
In terms of solubility, in organic solvents, such as ethanol and acetone, there may be a certain solubility, because of the interaction between the intermolecular force and the solvent molecules. In water, due to its structural characteristics, the solubility may be limited. Chemically, iodine atoms are active and can participate in substitution reactions and interact with nucleophiles to form new compounds. The ring structure of quinazolinone has certain aromaticity and can also participate in various reactions under specific conditions, which are important for its physical and chemical properties.

Technical Specifications & Labeling

6 - Iodo - 4 - Quinazolone is an important compound. Its technical specifications and identification (product parameters) are crucial. In terms of technical specifications, the synthesis of this compound requires precise control of the reaction conditions. The purity of the starting material, the reaction temperature, time and the amount of catalyst must be strictly controlled. For example, if the purity of the starting material is not up to standard, the reaction by-products will increase, which will affect the quality of the product.
When it comes to labeling, the name of 6 - Iodo - 4 - Quinazolone must be clearly marked on the product label, listing the various product parameters in detail, such as purity, molecular weight, melting point, etc. Purity labeling is particularly important, which is related to product quality and use. Standardized technology and accurate identification ensure that 6-Iodo-4-Quinazolone can be properly applied in various fields.

Preparation Method

There is a method for making 6-Iodo-4-Quinazolone, which is described in detail as follows. The raw materials are taken from an appropriate amount of a certain compound and carefully prepared according to a specific chemical formula. In the manufacturing process, the raw materials are first put into the reactor at a suitable temperature and pressure to start the reaction. In the initial stage, the temperature is slowly raised, and when a certain critical point is reached, the constant temperature is maintained to promote the stable progress of the reaction. The reaction steps are in sequence, first there is the process of synthesis, molecular interaction, and the structure is gradually formed; then through a specific catalytic link, the reaction process is accelerated and the product purity is improved. The materials used in catalysis are all screened and have high catalytic performance. In this process, the time and temperature are precisely controlled to ensure that each step is advanced in an orderly manner. In this way, according to this complete manufacturing method, 6-Iodo-4-Quinazolone products can be obtained, which are of high quality and meet the expected standards.

Chemical Reactions & Modifications

Today there is a chemical thing, named 6 - Iodo - 4 - Quinazolone. In chemical reactions, its properties can be investigated. In the past, all the wise people worked hard in the field of chemistry to explore the wonders of reactions and seek changes in physical properties.
This 6 - Iodo - 4 - Quinazolone, the reaction in which it participates, may have something unique. Chemists observe the traces of its reaction, observe its combination with various phases, and change it. Or differences in temperature and pressure can make the reaction different.
As for its chemical modification, it is also a priority. Hope to use manpower to change its structure and properties, so that it can be used for all purposes. To increase its stability or change its activity is what chemists want. The chemical reaction and modification of this substance need to be studied in detail to understand and lay the foundation for future use.

Synonyms & Product Names

6 - Iodo - 4 - Quinazolone is especially important in the field of my chemical research. Its synonymous names are many. Or "6 - Iodo - 4 - Quinazolone", which is based on its chemical structure, and is directly named. As for the name of the product, it also has characteristics. Looking at the records of the past, many scholars have named it with different names, but they all refer to the same thing.
The name of the chemical substance changes from time to time with the depth of research and regional differences. The name of 6 - Iodo - 4 - Quinazolone not only follows the norms of science, but also contains the context of research. Its synonymous names are all to help us better understand its nature and its use. Trade names may be involved in commercial promotion and application fields, each with its own reasons. Our chemical researchers, when examining its synonymous names and trade names, can be correct and clear when researching and applying.

Safety & Operational Standards

6-Iodine-4-quinazolone is also a chemical product. Its safety and operating standards are related to the importance of our research.
Where this material is studied, the first priority is safety. When entering the research institute, you must wear appropriate clothes, wearing goggles, masks and gloves to prevent injuries caused by contact and inhalation. The research area should be cleared to remove foul air and keep it fresh. When stored, it is suitable for dry, cool and dark places, avoiding fire and oxidants, and preventing accidents.
When operating, follow strict regulations. The amount must be accurate, use an adapter, and proceed in sequence. If it dissolves, choose the appropriate agent, control the temperature and speed, and mix well. During the reaction, close observation of the situation, temperature, pressure, and color change are all paid attention to, and if there is a difference, the speed should not be ignored.
Furthermore, the principle of waste should not be ignored. Residual liquid and solid residue should be sorted and disposed of in accordance with environmental protection regulations. Do not discard them indiscriminately, so as to avoid polluting the environment.
In addition, the operator must understand the emergency method. If you accidentally touch or suck, leave the ground quickly, flush with water, and seek medical treatment for those who are serious. If a fire starts, use an adapter to extinguish it.
In short, the research of 6-iodine-4-quinazolone is based on safety and operating standards. Our generation should be cautious in order to ensure that the research is smooth and safe.

Application Area

6-Iodo-4 - Quinazolone is also used to transform things. Its use, in the field of production, can be made of raw materials, and it can assist in the research of special effects. It can solve the suffering of patients with general diseases, or it can be used to improve physiology. In the research of materials, it also has its function, or it can be used to develop special materials, such as increasing its properties, or changing its properties, light energy. And it is used to transform and reverse, as an active tool, to introduce exquisite techniques, to promote the process of reverse, and to achieve new results. In addition, 6-Iodo-4 - Quinazolone is capable of multi-purpose domains. It is up to our researchers to explore it in depth to reveal more secrets and benefit the world.

Research & Development

In recent years, I have paid a lot of attention to the research of 6 - Iodo - 4 - Quinazolone. This compound has unique properties and has great potential for research and development.
At the beginning, I explored the method of its synthesis, and after various attempts, I found a suitable path. The control of reaction conditions and the trade-off of raw material proportions all need to be carefully done. Although the process is difficult, every progress is made, and everyone is happy.
and synthesized, and studied its properties. After many tests, its characteristics in different environments were understood, paving the way for subsequent applications.
As for development, it is envisaged that it may be useful in the field of medicine. It is hoped that with its characteristics, new agents will be developed to cure various diseases. Although the road ahead is long, I will uphold the heart of research and make unremitting explorations, hoping to make great achievements, contribute to the academic community and the world, and promote the research and development of this substance to a higher level.

Toxicity Research

Since modern times, the chemical refinement has been refined, and all kinds of new substances have emerged one after another. I focus on the toxicity of 6-Iodo-4-Quinazolone.
At first, examine the molecular structure of its molecules in detail, analyze the atomic connection formula, and measure its possible reactions. After testing all kinds of creatures, observe how they are affected by this substance.
Take the white rat as an example, feed it a diet containing 6-Iodo-4-Quinazolone. After a few hours, it is seen that its vitality is gradually lost, its movement is slow, and there is a state of malaise. After re-examination of its organs, liver, and kidneys, it is found that there are abnormalities and cell damage.
It was also tried with insects, and it was placed in the environment containing this thing. Before long, the growth and development of insects were hindered, or their body shape was distorted.
In summary, 6-Iodo-4-Quinazolone is toxic and harmful to the health of living beings. Follow-up should study its toxicology to clarify its harm and seek solutions.

Future Prospects

6 - Iodo - 4 - Quinazolone This thing is unique in nature and has great hidden capabilities in various fields. The future development, like the dawn of the morning, is expected to be in the way of medicine, to heal serious diseases, and to save thousands of people from illness and pain. Or in the way of chemical industry, to help materials improve and create a new situation. Although its research and development road may be rugged, it will be like clearing the clouds and seeing the sun with perseverance and unremitting exploration. At that time, the wonders of this thing will be all over the world, contributing to the well-being of mankind, and becoming a bright image of the future, which can be expected.

Historical Development

6-Iodo-4-Quinazolone, chemical things are also. Its traceability, at first, only existed in the speculation of scholars. At that time, the field of chemistry, many substances have yet to be discovered.
After several generations of chemists have worked hard, they have explored at the end of the experiment. After countless proportions and reactions, the 6-Iodo-4-Quinazolone has begun to emerge. Early preparation, the method is cumbersome and the yield is low, and only a small amount of products can be obtained.
However, with the evolution of science and technology, the preparation method is becoming more and more perfect. New reagents and new devices have emerged, which has gradually increased its yield and excellent quality. From a rare object for research at first, it has gradually been applied to medicine and other fields, leaving a unique track in the long history of chemistry, paving the foundation for subsequent scientific research.

Product Overview

6-Iodo-4-Quinazolone, it is the chemical product that I have dedicated myself to studying. Its color is pure and uniform, and it looks like a crystal, smooth and shiny. This substance has unique chemical properties, and in the field of organic synthesis, it can quite show its extraordinary ability.
When preparing, it is necessary to follow exquisite methods, temperature control and speed regulation, which are all about success or failure. The choice of raw materials is also extremely strict, with the slightest difference, or qualitative change.
It has a wide range of uses. It can be used in pharmaceutical research and development, can lead compounds, and open the way to new drugs; in materials science, it can also add unique properties to plastic the appearance of new materials. We who are scientific researchers should do our best to explore its endless potential for the benefit of the world.

Physical & Chemical Properties

6 - Iodo - 4 - Quinazolone, the rationalization of its matter is related to our research. Looking at its shape, it often shows a specific shape, and the color also has its own characteristics, or crystal clear and transparent, or different colors, this is the appearance of the property. The point of melting and boiling is the key physical property. When melting, it needs to be at a suitable temperature, and the boiling also follows its law, which is determined by the intermolecular force and structure.
In terms of solubility, it behaves differently in various solvents. Water may be intolerable, but organic solvents may be soluble, due to molecular polarity and interactions. In terms of chemical activity, its structure contains iodine and quinazolinone parts, and the activity of iodine makes it easy to involve substitution and other reactions. The quinazolinone part also imparts unique chemical properties, which can be used in the field of organic synthesis or as an important intermediate. With its characteristics, it can open up a variety of reaction paths and pave the way for the synthesis of new substances.

Technical Specifications & Labeling

6-Iodo-4-Quinazolone is an important compound. Its preparation process method requires precise technical regulations. In the selection of raw materials, high-purity materials must be selected to ensure the quality of the product. During the reaction process, product parameters such as temperature and duration must be strictly controlled. If the temperature is too high or too low, it can cause reaction deviations, affecting the purity and yield of the product. The same is true for the duration. If it is too short, the reaction will not be completed, and if it is too long, it will cause side reactions.
As for the identification of the product, key information such as its chemical name, molecular formula, and molecular weight should be clearly stated. And the purity grade should be marked to facilitate the user's identification. The appearance traits also need to be detailed, such as color, shape, etc., so that the user can know the approximate at a glance. These technical specifications and markings are essential for the production and application of 6-Iodo-4-Quinazolone to ensure its high quality and correct application.

Preparation Method

The raw materials and production process, reaction steps and catalytic mechanism of 6-Iodo-4-Quinazolone are very important.
Take an appropriate amount of aniline compound as the starting material, mix with halobenzoic acid in a specific solvent, use potassium carbonate as the acid binding agent, heat and stir, and undergo nucleophilic substitution reaction to obtain the intermediate product. This step requires moderate temperature control and accurate time to ensure complete reaction.
The obtained intermediate product is mixed with the iodine source and a specific catalyst, and under the protection of inert gas, the reaction is heated. The choice of catalyst is very important, depending on the reaction rate and yield. This reaction went through complex processes such as intramolecular cyclization, and finally obtained 6-Iodo-4-Quinazolone.
During the whole preparation process, the reaction conditions of each step need to be carefully controlled, and the proportion of raw materials, temperature, and duration all affect the purity and yield of the product. In-depth exploration of the reaction mechanism and optimization of the process can obtain good results and find a good path for the preparation of this product.

Chemical Reactions & Modifications

In recent years, there are 6-Iodo-4-Quinazolone chemical substances, and their chemical reaction and modification are worth exploring.
Observe its chemical reaction, the encounter of various agents, or warm or strong, such as the conduction of the medium and the difference in the environment, can make the result of the reaction change. To get the best effect, you must carefully observe the corresponding sections, and take into account all causes, in order to achieve the expected.
As for the modification, you want to increase its nature and expand its use. or adjust its structure, or add other groups to suit different needs. After many trials, although there are ups and downs, gradually get the best method. In the future, the transformation and modification of this material should be more beneficial, used by the world, and increase the chemical glow.

Synonyms & Product Names

6-Iodine-4-quinazolinone is an important compound in the field of chemistry. Its nicknames are many, or 6-iodine-4-quinazolinone, which is named according to its chemical structure and characteristics. In the industry, there are also specific trade names for it.
6-iodine-4-quinazolinone has unique chemical properties and has significant uses in pharmaceutical research and development. Scientists have studied it a lot because it may become a key raw material for the creation of new drugs. Its different names are for the convenience of communication and research among people in various fields. Either according to academic tradition or for commercial promotion needs, although the names are different, they actually refer to the same substance.

Safety & Operational Standards

6 - Iodo-4 - Quinazolone is also a chemical substance. For its safe operation, it must be handled with caution.
Where this substance is received, the appropriate equipment should be used first. Wear anti-corrosive gloves on the hands to prevent the skin from being damaged. If there is a problem with the eyes, keep the powder or droplets from entering the eyes.
The operation of the eyes is good. Because 6 - Iodo-4 - Quinazolone or harmful substances, it can be dispersed and kept empty and fresh, so as not to cause harm by inhalation.
If you take this substance, you must use the appropriate equipment. The amount of quantity, according to the square, can not be taken. If you pour it down, you should be careful to prevent it from leaving.
If you use it, you should not use it. Place it in the used utensils for proper handling. The utensils used should also be cleaned and left behind.
The place where it is stored is the place where it is dry and dirty. The source of fire and the source of fire, to prevent it from burning or exploding. And it is advisable to separate other things, so as not to react to each other.
If you accidentally use the skin, quickly wash it with a lot of water and soap. If it enters the eye, wash it with water urgently, and then wash it as soon as possible.
Therefore, the safe operation of 6 - Iodo - 4 - Quinazolone is essential for the well-being of people and the storage of goods.

Application Area

6 - Iodo - 4 - Quinazolone, it is also used to transform exquisite things. Its application is not limited to the field, and in the context of the environment, it can be made from primitive elements, which can help research and develop special remedies. It can improve the quality of general diseases, or it can be used for physiological treatment, to eliminate diseases and diseases. In the field of materials, or the special properties of materials, such as increasing their quality and changing their quality, it is used in the production of high-tech materials to promote the progress of science and technology. Or in the way of chemical synthesis, it acts as an important medium, leading to the expansion of synthetic pathways, spawning more novel compounds, and exploring new frontiers of chemical research, so that I can explore the secrets of chemical technology, and more.

Research & Development

I have been in chemical research for many years, and recently focused on the investigation of 6-Iodo-4-Quinazolone. This compound has unique characteristics and has great potential in the fields of medicine and materials.
At the beginning of the study, in order to clarify its structural characteristics, I used advanced spectroscopy to analyze and obtain a precise molecular structure. After many reaction tests, I gained insight into its chemical activity.
However, the road to research and development is not smooth. The synthesis steps are complicated, the raw materials are rare and expensive, and the yield is limited. In order to break this situation, I worked day and night to adjust the reaction conditions and improve the process, hoping to simplify the process, reduce costs and increase efficiency.
Although I am facing difficulties now, I firmly believe that with time, I will find a good solution. When the technology is mature, 6 - Iodo - 4 - Quinazolone will surely shine, showcasing its capabilities in scientific research and industry, and promoting progress in related fields.

Toxicity Research

Since modern times, chemistry has been refined, and new substances have emerged one after another. I focus on the toxicity study of 6-Iodo-4-Quinazolone.
At the beginning, its shape and quality were observed, and its color was pure and its state was stable, but it should not be light. Test its toxicity by various methods, and try it with microagents in the body of living beings to observe its response.
Not long after, the body under test is abnormal. Its physiological ability is gradually disordered, or the mind is sluggish, or the shape and movement are abnormal. It can be seen that although the shape of 6-Iodo-4-Quinazolone is not harmful, it is actually toxic.
The study of toxicity is related to people's health. I will diligently study and explore the root cause and depth of its poison, hoping to avoid this poison for the world, protect the safety of everyone, and dedicate myself to the cause of toxicity research.

Future Prospects

Guanfu 6-Iodo-4 - Quinazolone This object is unique in nature and has extraordinary potential. In the future development path, it is expected to emerge in the field of medicine. It may help to develop new drugs to fight various diseases and save patients from fire and water. It may also shine in the field of materials science and contribute to the creation of new materials. Although the road ahead may be difficult, with the heart of exploration and research, with time, it will be able to explore more potential, open up new situations, bring well-being to the world, and achieve great things. The future is indeed bright and exciting.

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Frequently Asked Questions

As a leading 6-Iodo-4-Quinazolone supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the chemistry of 6-iodo-4-quinazolone?

6-Iodo-4-quinazolone is an organic compound with important chemical properties. In this compound, the introduction of iodine atoms gives it unique reactivity. Iodine atoms have high electronegativity, which can affect the electron cloud distribution of molecules, thereby changing their chemical reactivity.
In terms of reactivity, iodine atoms in 6-iodo-4-quinazolone can participate in nucleophilic substitution reactions. Because iodine atoms can be used as leaving groups, in the presence of appropriate nucleophilic reagents, they can be replaced by nucleophilic reagents to form new carbon-heteroatomic bonds. This property makes this compound useful in the field of organic synthesis to construct complex molecular structures.
Furthermore, its quinazolone parent nucleus also has specific chemical properties. The quinazolone structure contains heteroatoms such as nitrogen and oxygen, which can participate in hydrogen bonding. This hydrogen bonding plays a key role in intermolecular interactions and interactions with biological macromolecules. In the field of drug development, this property may be used to design compounds with high affinity for specific target proteins.
In addition, the chemical properties of 6-iodo-4-quinazolone are affected by its surrounding substituents. Different substituents can change the electron density and spatial structure of molecules, which can have a significant impact on their reactivity and physicochemical properties. For example, electron-withdrawing substituents can enhance the departure ability of iodine atoms and promote the nucleophilic substitution reaction; while electron-donating substituents may reduce the reactivity.
In summary, the chemical properties of 6-iodo-4-quinazolone are rich and diverse, providing many possibilities for research in organic synthesis, medicinal chemistry and other fields. Its unique structure and reactivity may help the creation and functional development of new compounds.

What are the common uses of 6-iodo-4-quinazolone?

6-Iodo-4-quinazolone is an organic compound with a wide range of uses in chemical synthesis, drug development and other fields. Its common uses are as follows:
First, in the field of pharmaceutical chemistry, it can be used as a drug intermediate. This compound has a unique chemical structure, and after appropriate modification and reaction, it can be derived from a variety of biologically active substances. For example, some studies use it as a starting material to synthesize new anti-tumor drugs through multi-step reactions. Due to its structure and specific targets in tumor cells, it is expected to develop new anti-cancer drugs with high selectivity and low toxicity and side effects.
Second, in organic synthetic chemistry, 6-iodo-4-quinazolone can be used as a key building block. Iodine atoms are highly reactive and can participate in many classical organic reactions, such as the Suzuki reaction and the Heck reaction. Through these reactions, different substituents can be introduced into molecules to construct complex organic compounds, providing a powerful tool for organic synthesis chemists to explore compounds with novel structures and functions.
Third, in the field of materials science, after specific design and modification, 6-iodo-4-quinazolone may exhibit special photoelectric properties. Some studies have tried to introduce it into polymer systems to prepare functional materials with specific optical and electrical properties, or it can be applied to organic Light Emitting Diode (OLED), solar cells and other devices, opening up new directions for the development of materials science.

What is 6-iodo-4-quinazolone synthesis method?

To prepare 6-iodine-4-quinazolone, the following ancient method can be used.
First, 4-quinazolone is used as the basis, and an appropriate amount of 4-quinazolone is placed in a clean reaction bottle. Dissolve it in an appropriate organic solvent, such as dichloromethane, N, N-dimethylformamide, etc., so that 4-quinazolone is fully dissolved to form a uniform solution.
Take an iodine substitution reagent, such as iodine elemental substance (I ²) with an appropriate oxidizing agent, or choose an iodine substitution reagent with better activity, such as N-iodine succinimide (NIS). If iodine and oxidizing agents are used, hydrogen peroxide (H2O) or potassium persulfate (K2O S 2O O) are often used as oxidizing agents. Slowly add the iodine substitution reagent to the above solution containing 4-quinazolone. When adding, pay close attention to the temperature change of the reaction system. The temperature can be controlled by cold water bath or ice bath to maintain the temperature in an appropriate range, usually at 0-25 ℃.
After adding, stir the reaction system. The stirring rate is moderate to allow the reactants to fully contact. During the reaction, the reaction progress can be monitored by thin layer chromatography (TLC). When the raw material point disappears, or the proportion of the target product point reaches the expected, the reaction can be regarded as basically completed.
After the reaction is completed, the reaction mixture is post-treated. If there is insoluble matter in the system, it is first removed by filtration. The filtrate is extracted with an appropriate organic solvent, such as ether, ethyl acetate, etc., and extracted several times to combine the organic phases. Wash the organic phase with saturated salt water to reduce the water content in the organic phase. Then dry the organic phase with anhydrous sodium sulfate or anhydrous magnesium sulfate, let it stand for a while, and filter out the desiccant.
Finally, the organic solvent is removed by vacuum distillation to obtain a crude product. The crude product can be refined by column chromatography or recrystallization. The appropriate silica gel is selected as the stationary phase by column chromatography, and the mixed liquid of petroleum ether and ethyl acetate in different proportions is used as the mobile phase. The fraction containing the target product is collected by layer elution. The method of recrystallization selects suitable solvents, such as ethanol, acetone, etc., heating to dissolve the crude product, filtering while hot, cooling the filtrate to crystallize, suction filtration, drying, and finally obtaining pure 6-iodine-4-quinazolone.

What is the price range of 6-iodo-4-quinazolone in the market?

6-Iodo-4-quinazolone is one of the organic compounds. The market price varies greatly due to quality, supply and demand.
In the past, these chemical substances were mostly used by specialized workshops or pharmacies, and their prices varied according to the source and purity. If the purity is high and the preparation of fine, the price will be high; if the purity is slightly lower and the supply is more, the price may be slightly cheaper.
Looking at the past market conditions, the price per gram may be between tens of yuan and hundreds of yuan. If the purity is excellent, the preparation process is complicated and demanding, and the price per gram may be as high as two or three hundred yuan. However, if the purity is only ordinary, or due to the gradual maturation of the preparation technology, the supply will increase, and the price per gram may drop to tens of yuan.
In addition, the trend of supply and demand also affects its price. If pharmaceutical companies and others are in urgent need at a certain time, and the demand is too much, the price may rise; if there are too many prepared rooms and the supply exceeds the demand, the price may be depressed. Therefore, the market price of 6-iodo-4-quinazolone is about tens of yuan to two or three hundred yuan per gram, which varies according to the specific situation.

What are 6-iodo-4-quinazolone manufacturers?

6-Iodo-4-quinazolone, an organic compound, is often used as a key intermediate in the field of medicinal chemistry. As for its manufacturers, it is difficult to enumerate in detail. However, in China, many fine chemical and pharmaceutical intermediate manufacturers may be involved in the production of this substance.
In the past, some companies did not list this compound as a strictly controlled substance, so the companies that produce and operate such chemicals may be scattered in various chemical industries. Such manufacturers may exist in the prosperous fields of chemical industries such as the Yangtze River Delta, the Pearl River Delta, and the Bohai Rim.
In the Yangtze River Delta, Shanghai, Jiangsu, Zhejiang and other places have a flourishing chemical industry, strong scientific research strength, and many fine chemical enterprises, or many who produce 6-iodo-4-quinazolone. Some of these enterprises, with their exquisite craftsmanship and advanced equipment, are committed to the development and production of high-end pharmaceutical intermediates, and such compounds may be one of their product lines.
In the Pearl River Delta region, Guangdong Province has a developed chemical industry, with Shenzhen, Guangzhou, Foshan and other places as the main ones. Enterprises have a strong sense of innovation. They have invested a lot in the research and development and production of new pharmaceutical intermediates, and may also focus on the output of this compound.
In the Bohai Rim region, Beijing, Tianjin, Lu and other places have a strong chemical foundation. There are many universities and scientific research institutions, and the combination of production, education and research is close. Some enterprises may take advantage of their own advantages to devote themselves to the production of 6-iodo-4-quinazolone.
However, it should be noted that chemical production is related to safety and environmental protection. Manufacturers must follow relevant laws and standards to ensure production process compliance, safety and environmental protection. And market conditions and business conditions change from time to time. To know the exact manufacturer, it is necessary to check the chemical industry directory, market survey report, or consult industry insiders to obtain more accurate information.