6 Iodobenzofuran 3 One
Iodobenzene

6 Iodobenzofuran 3 One

Fengxi Chemical

Specifications

HS Code

924072

Chemical Formula C8H5IO2
Molecular Weight 260.03
Appearance Solid (usually)
Physical State At Room Temperature Solid
Melting Point Specific value would require experimental data
Boiling Point Specific value would require experimental data
Solubility In Water Low (expected, due to non - polar nature of benzene ring)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Density Specific value would require experimental data
Odor Odorless or faint odor (expected for this type of heterocyclic compound)
Chemical Formula C8H5IO2
Molecular Weight 262.03
Appearance Solid (usually)
Melting Point Data needed
Boiling Point Data needed
Density Data needed
Solubility In Water Low (expected, due to non - polar nature of the aromatic part)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform (expected)
Pka Data needed
Stability Stable under normal conditions but may react with strong oxidizing or reducing agents
Chemical Formula C8H5IO2
Molar Mass 262.03 g/mol
Appearance Solid (predicted, no common color data)
Solubility In Water Low, due to non - polar benzene and furan rings
Solubility In Organic Solvents Moderate to high in common organic solvents like dichloromethane
Pka No widely - available data, likely acidic due to carbonyl group
Reactivity Reactive at the iodine - substituted position and carbonyl group, can participate in nucleophilic substitution and carbonyl - addition reactions
Chemical Formula C8H5IO2
Molecular Weight 262.03
Appearance Solid (predicted)
Melting Point No data available
Boiling Point No data available
Density No data available
Solubility In Water No data available
Solubility In Organic Solvents No data available
Flash Point No data available
Pka No data available
Packing & Storage
Packing 100g of 6 - iodobenzofuran - 3 - one packaged in a sealed, chemical - resistant container.
Storage 6 - iodobenzofuran - 3 - one should be stored in a cool, dry, well - ventilated area away from heat sources and ignition sources. Keep it in a tightly closed container to prevent exposure to air and moisture. Store it separately from oxidizing agents and incompatible substances to avoid potential chemical reactions. This storage method helps maintain its stability and safety.
Shipping 6 - iodobenzofuran - 3 - one is shipped in well - sealed, corrosion - resistant containers. Packaging adheres to chemical transport regulations. Shipment is via approved carriers, ensuring proper handling and storage to prevent damage and leakage.
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6-iodobenzofuran-3-one 6-iodobenzofuran-3-one 6-iodobenzofuran-3-one
General Information
Frequently Asked Questions
What is the chemical structure of 6-iodobenzofuran-3-one?
6-Iodobenzofuran-3-one is one of the organic compounds. Looking at its name, the approximate chemical structure can be deduced. "Benzofuran" contains the structure of a benzene ring and a furan ring. The two are connected by a common two-carbon atom, thus forming a unique heterocyclic system. And "3-one" shows that there is a carbonyl group (C = O) at the third position of the benzofuran ring. The characteristics of carbonyl are active. It is often a key check point in chemical reactions and can participate in many reactions, such as nucleophilic addition. Furthermore, "6-iodine" is expressed in the sixth position of the benzofuran ring, connected with an iodine atom. The iodine atom has a large atomic radius and electronegativity, which affects the electron cloud distribution and spatial structure of the molecule, and can change the polarity and reactivity of the molecule. The structure of this compound gives it unique physical and chemical properties, and it may have potential uses in organic synthesis, pharmaceutical chemistry and other fields. Due to the synergistic action of various parts of its structure, it can trigger a variety of chemical reactions to prepare more complex compounds with specific functions.
What are the physical properties of 6-iodobenzofuran-3-one?
6-Iodobenzofuran-3-one is a kind of organic compound. Its physical properties are quite unique. Under normal temperature and pressure, it is mostly in the shape of a solid state. Looking at its color, or white to light yellow crystalline powder, this color characteristic is like the purity of the first snow in winter, and the elegance of the early blooming of autumn chrysanthemum.
When it comes to the melting point, it is about a specific range. This value is like an accurate scale, measuring the critical temperature of its transition from solid to liquid. And it has a certain solubility, in organic solvents such as dichloromethane, N, N-dimethylformamide, can show good solubility characteristics, just like fish entering water, natural fusion, this solubility, from the law of molecular interactions.
The stability of 6-iodobenzofuran-3-one is also a key physical property. Under normal environmental conditions, it is relatively stable, but when it encounters hot topics, open flames or strong oxidants, it is like an enemy, easy to cause dangerous reactions, just like a calm lake surface suddenly attacked by strong winds, ripples appear, which may lead to more violent changes. In addition, its density is also a specific value. This density characteristic, like the inherent sign of an object, affects its existence and behavior in different media. The physical properties of this compound are of great significance in many fields such as organic synthesis and medicinal chemistry. It is like a cornerstone in a tall building, laying a solid foundation for related research and application.
What are the common synthetic methods of 6-iodobenzofuran-3-one?
6-Iodobenzofuran-3-one is also an important compound in organic synthesis. There are several common synthesis methods.
First, benzofuran-3-one is used as the starting material, and iodine atoms are introduced by halogenation reaction. In an appropriate reaction solvent, such as dichloromethane, N, N-dimethylformamide, etc., a halogenating agent, such as N-iodosuccinimide (NIS), is added, and a suitable catalyst is supplemented, such as Lewis acid (such as aluminum trichloride) or a free radical initiator (such as azobisisobutyronitrile, AIBN). If Lewis acid is used as a catalyst, its function is to activate the aromatic ring of benzofuran-3-one, so that the iodine atom can more easily replace the hydrogen atom at a specific position on the aromatic ring; if a free radical initiator is used, the free radical reaction process is initiated, which prompts the iodine atom to react with benzofuran-3-one to obtain 6-iodobenzofuran-3-one.
Second, the benzene derivative containing a suitable substituent can be started. The benzofuran ring system is first constructed through a series of reactions, and then the iodine atom is introduced. For example, using o-hydroxybenzoic acid derivatives as starting materials, through esterification and reaction with halogenated hydrocarbons to form ether bonds, etc., the precursor of benzofuran ring is constructed. Then, as in the above halogenation reaction, iodine atoms are introduced under suitable conditions, and the target product is obtained through multi-step reaction. Although this approach is slightly complicated, it requires stricter control of raw material selection and reaction conditions, but it can effectively improve the selectivity and yield of the product.
Third, the coupling reaction catalyzed by metal is also a good method for synthesis. The coupling reaction of borate ester or halogen containing benzofuran-3-ketone structure with iodide reagent under the action of metal catalyst (such as palladium catalyst, such as tetra (triphenylphosphine) palladium, etc.) occurs. In the reaction, the metal catalyst first forms an active intermediate with the substrate and iodide reagent, and then forms a carbon-iodine bond through the steps of oxidation addition, transmetallization and reduction elimination, thereby synthesizing 6-iodobenzofuran-3-one. This method has mild conditions and good tolerance to functional groups, and is widely used in the field of organic synthesis.
In what areas is 6-iodobenzofuran-3-one applied?
6-Iodobenzofuran-3-ketone is used in various fields. In the field of medicine, it may be a key raw material for the creation of new drugs. Due to its unique structure and specific chemical activity, it can interact with many targets in organisms, or it can develop drugs that are effective for specific diseases, such as targeting certain tumor cells, with its special structure to precisely inhibit tumor cell growth, or developing drugs for the treatment of neurological diseases, acting on the regulation of neurotransmitters.
In the field of materials science, this compound is also promising. Or it can be used to prepare polymer materials with special properties. With its unique chemical structure, the materials are endowed with excellent optical properties, such as excellent optical properties, so that the materials can be used in optoelectronic devices, such as Light Emitting Diodes, light sensors, etc.; or the materials are endowed with special electrical properties and applied to the research and development of new conductive materials.
Furthermore, in the field of organic synthesis chemistry, 6-iodobenzofuran-3-one is an important synthesis intermediate. Chemists can use various chemical reactions as starting materials to build more complex and diverse organic molecular structures, contributing to the development of organic synthetic chemistry, and helping to create more organic compounds with unique properties and functions, thus promoting the progress of the entire field of organic synthesis.
What is the market outlook for 6-iodobenzofuran-3-one?
6-Iodobenzofuran-3-one, an organic compound, has attracted much attention in the field of chemical and pharmaceutical research and development. Its market prospects are actually both opportunities and challenges.
Looking at its opportunities, in terms of pharmaceutical creation, this compound has a unique chemical structure, or has potential applications in new drug development. Due to the birth of many new drugs, it is often derived from organic compounds with special structures. Studies have found that such benzofuranone derivatives may have biological activities, such as anti-tumor and anti-inflammatory effects. Therefore, if its pharmacological mechanism can be deeply explored and developed into a drug, the market potential is limitless.
Furthermore, the field of materials science also has potential. With the advance of science and technology, the demand for special performance materials is increasing. 6-Iodobenzofuran-3-one may be chemically modified and applied to optical materials, electronic materials, etc. If some iodine-containing organic compounds have unique optical and electrical properties in optoelectronic devices, this compound may follow this path to develop new applications.
However, its challenges cannot be ignored. The complexity of the synthesis process is a major obstacle. Preparation of 6-Iodobenzofuran-3-one requires precise control of reaction conditions, many steps and high cost. If the process cannot be optimized and costs reduced, large-scale production and marketing activities will be difficult.
In addition, the market competition is quite fierce. The field of chemical synthesis is developing rapidly, and compounds with similar structures may have come out and occupy part of the market share. To stand out, not only technological innovation is required, but also efficient marketing activities and marketing strategies.
In summary, although 6-iodobenzofuran-3-one has market potential, if you want to open up the market, you need to break through the synthesis process problems and deal with fierce competition in order to gain a place in the market.