6a 4 Chlorophenyl 8 4 Fluorophenyl Amino 6 4 Hydroxy 3 Iodo 5 Methoxyphenyl 2 2 4 Hydroxyphenyl Ethyl 3a 4 6 6a 9a 10 10a 10b Octahydroisoindolo 5 6 E Isoindole 1 3 7 9 2h 8h Tetrone
Iodobenzene
6a-(4-chlorophenyl)-8-[(4-fluorophenyl)amino]-6-(4-hydroxy-3-iodo-5-methoxyphenyl)-2-[2-(4-hydroxyphenyl)ethyl]-3a,4,6,6a,9a,10,10a,10b-octahydroisoindolo[5,6-e]isoindole-1,3,7,9(2h,8h)-tetrone
FAQ

This product 6a- (4-chlorophenyl) -8- [ (4-fluorophenyl) amino] -6- (4-hydroxy-3-iodine-5-methoxyphenyl) 2- [2- (4-hydroxyphenyl) ethyl] -3a, 4,6,6a, 9a, 10,10a, 10b-octahydroisoindolo [5,6-e] isoindole-1,3,7,9 (2H, 8H) -tetraketone What are the characteristics of the chemical structure?

This compound is named 6a- (4-cyanobenzyl) -8- [ (4-hydroxybenzyl) amino] -6- (4-fluoro-3-chloro-5-methoxybenzyl) -2- [2- (4-fluorobenzyl) ethyl] -3a, 4,6,6a, 9a, 10,10a, 10b-octahydroisoindolo [5,6-e] isoindole-1,3,7,9 (2H, 8H) -tetraone. Its chemical structure characteristics are as follows:
1. ** Fused ring system **: A fused ring structure with isoindolo [5,6-e] isoindoles, which imparts a unique rigidity and spatial structure to compounds, affecting the physicochemical properties and biological activities of molecules, such as determining the way and affinity of their binding to specific targets in vivo.
2. ** Multiple substituents **: Numerous substituents are connected at different positions in the fused ring. 4-Cyanobenzyl, 4-hydroxybenzyl, 4-fluoro-3-chloro-5-methoxybenzyl and 2- (4-fluorobenzyl) ethyl and other substituents, their electronic effects and steric resistance have a significant impact on the properties of compounds. For example, the electron-absorbing properties of cyano groups can change the electron cloud distribution of molecules and affect their chemical reactivity; halogen, hydroxyl, methoxy and other substituents on different benzyl groups affect the lipophilicity, water solubility and interaction with biological macromolecules due to differences in electronic effects.
3. ** Carbonyl and Amino **: The structure contains multiple carbonyl and amino groups. Carbonyl groups have strong polarity and can participate in the formation of hydrogen bonds and other molecular interactions, affecting the solubility and melting point of compounds. Amino groups not only can form hydrogen bonds, but also may play a key role in chemical reactions or metabolic processes in vivo, such as participating in reactions as nucleophilic check points.
4. ** Chiral centers **: Although not explicitly mentioned, there may be chiral centers in complex structures. Chiral centers enable the presence of enantiomers in compounds. Different enantiomers may exhibit different activities, metabolic pathways and toxicity in organisms.

6A- (4-chlorophenyl) -8- [ (4-fluorophenyl) amino] -6- (4-hydroxy-3-iodine-5-methoxyphenyl) 2- [2- (4-hydroxyphenyl) ethyl] -3a, 4,6,6a, 9a, 10,10a, 10b-octahydro-isoindolo [5,6-e] isoindole-1,3,7,9 (2H, 8H) -tetraketone in which applications?

What Guan Jun asked is the doubt about the physical use of chemistry. The "6a- (4-benzyl) -8- [ (4-methylbenzyl) benzyl] -6- (4-naphthyl-3-bromo-5-methoxybenzyl) -2- [2- (4-naphthylbenzyl) ethyl] -3a, 4,6,6a, 9a, 10,10a, 10b -octahydroisoindolo [5,6-e] isoindole-1,3,7,9 (2H, 8H) -tetraketone". This substance may have applications in the fields of pharmaceutical chemistry and organic synthesis.

In pharmaceutical chemistry, such complex organic compounds may have unique biological activities and can be used as potential drug precursors. The diverse groups in its structure may interact with specific targets in organisms, such as proteins, enzymes, etc., to regulate biological processes, so it is used for disease treatment.

In the category of organic synthesis, it may be an important intermediate. With its special structure, it can use a variety of organic reactions to construct more complex molecular structures, which will help the development of new materials, natural product total synthesis and other fields.

In summary, this compound may play a key role in the fields of medicine and synthetic chemistry, paving the way for the development of innovative drugs and the creation of novel materials.

6A- (4-chlorophenyl) -8- [ (4-fluorophenyl) amino] -6- (4-hydroxy-3-iodine-5-methoxyphenyl) 2- [2- (4-hydroxyphenyl) ethyl] -3a, 4,6,6a, 9a, 10,10a, 10b-octahydroisoindolo [5,6-e] isoindole-1,3,7,9 (2H, 8H) -tetraketone What is the synthesis method?

To prepare 4,6,6a, 9a, 10,10a, 10b-octahydroisoindolo [5,6-e] isoindolo-1,3,7,9 (2H, 8H) -tetraketone, the synthesis method is as follows:

First, the raw material containing a specific group is processed. In the compound of 6a- (4-hydroxybenzyl) -8- [ (4-methylbenzyl) amino] -6- (4-fluorobenzyl-3-chloro-5-methoxybenzyl) -2- [2- (4-fluorobenzyl) ethyl] -3a.

Appropriate reaction conditions and reagents can be selected. For example, first dissolve the compound in a suitable solvent to create a stable reaction environment. Choosing a specific catalyst can speed up the reaction rate and make the reaction proceed in the desired direction.

During the reaction process, pay attention to the interaction between various groups. Hydroxybenzyl, methylbenzyl, fluorobenzyl and other groups may undergo substitution and condensation reactions due to different reagents and conditions. For example, under specific basic conditions, some benzyl groups may participate in nucleophilic substitution and combine with other reagents to change the molecular structure.

Furthermore, control the reaction temperature and time. If the temperature is too high or too low, it may affect the selectivity and rate of the reaction. Appropriate temperature, or between tens of degrees Celsius, allows each reaction to occur in an orderly manner. The control of time is also crucial. According to the progress of the reaction, monitoring by thin-layer chromatography and other means is required to stop the reaction in time to obtain the expected product.

Through a series of fine operations and reaction regulation, 4,6,6a, 9a, 10,10a, 10b-octahydroisoindolo [5,6-e] isoindole-1,3,7,9 (2H, 8H) -tetraketone can be synthesized. This process requires a thorough understanding of chemical principles and precise control of experimental operations to achieve ideal results.

What are the performance advantages of 6a- (4-chlorophenyl) -8- [ (4-fluorophenyl) amino] -6- (4-hydroxy-3-iodine-5-methoxyphenyl) 2- [2- (4-hydroxyphenyl) ethyl] -3a, 4,6,6a, 9a, 10,10a, 10b-octahydroisoindolo [5,6-e] isoindole-1,3,7,9 (2H, 8H) -tetraketone?

Fu 6a - (4 - methoxy) -8- [ (4 - methoxy) ethyl ester] -6- (4 - fluoro - 3 - chloro - 5 - methoxy phenoxy) - 2 - [2 - (4 - fluoro phenoxy) ethyl] - 3a, 4,6,6a, 9a, 10,10a, 10b - octahydroisoquinolo [5,6 - e] isoquinoline - 1,3,7,9 (2H, 8H) - tetraketone This product has three advantages in performance.

First, high chemical stability. Due to the interaction of multiple substituents in its structure, such as methoxy, fluoro, etc., it enhances the stability of intra-molecular electron cloud distribution, making the compound difficult to react with other substances in general chemical environment. It can be stored stably for a long time and is beneficial for storage and transportation.

Second, it has unique biological activities. The structure of octahydroisoquinoline and isoquinoline gives it a specific spatial configuration, which can precisely bind to specific targets in organisms, or affect enzyme activity, or interfere with cell signal transduction pathways. It may have potential application value in the field of medicine, or can be developed into new therapeutic drugs.

Third, good physical properties. The molecular structure endows it with suitable physical properties such as solubility and melting point, and has a certain solubility in organic solvents, which is convenient for solution preparation and reaction operations in experimental operations and practical applications. The appropriate melting point is also conducive to its processing under specific conditions.

6a- (4-chlorophenyl) -8- [ (4-fluorophenyl) amino] -6- (4-hydroxy-3-iodine-5-methoxyphenyl) 2- [2- (4-hydroxyphenyl) ethyl] -3a, 4,6,6a, 9a, 10,10a, 10b-octahydroisoindolo [5,6-e] isoindole-1,3,7,9 (2H, 8H) -tetraketone What is the market prospect?

The question asked by Guan Fu is about 6a- (4-methoxy) -8- [ (4-methoxy) ethoxy] -6- (4-fluoro-3-chloro-5-methoxyphenoxy) -2- [2- (4-fluorophenoxy) propyl] -3a, 4,6,6a, 9a, 10,10a, 10b -octahydroisoindolo [5,6-e] isoindole-1,3,7,9 (2H, 8H) -tetraketone market prospects.

The exploration of the market prospects of this compound requires multiple considerations. First, looking at the field it belongs to, if it is related to medicine, its pharmacological activity and clinical effect need to be considered. If it has significant efficacy against a stubborn disease, can fill the gap in the market, or is better than existing drugs, the prospect is promising. The pharmaceutical market focuses on efficacy and safety. If this compound is rigorously tested and proved to be safe and effective, it will definitely attract the attention of pharmaceutical companies, and then be put into R & D and production to occupy a place in the market.

Second, consider the difficulty and cost of synthesis. If the synthesis process is complicated and expensive, even if the efficacy is excellent, it may be limited. If the cost is too high, the price of the product will rise, consumers will be unable to bear it, and market acceptance will be reduced. It is necessary to weigh the difficulty and cost control of the synthesis process and seek an economically feasible method.

Third, look at the market competition situation. If there are many congeneric products and the competition is fierce, you need to highlight your own advantages. Or for better curative effect, or for less side effects, or for the price to be close to the people. Only in this way can you win market share.

Fourth, policies and regulations are also the key. The pharmaceutical field is strictly regulated, and compounds need to meet many regulatory requirements. If they can comply with the policy orientation and pass various approvals, they can enter the market smoothly.

Overall, the market prospect of this compound has both opportunities and challenges. It is necessary to comprehensively evaluate factors such as pharmacology, cost, competition, and regulations in order to make a more accurate judgment on its market prospects.