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What is the chemical structure of 7-iodopyrrolo [2,1-f] [1,2,4] triazin-4-amine
7 - iodopyrrolo [2,1 - f] [1,2,4] triazin - 4 - amine is the English name of an organic compound. Its chemical structure is explained in the classical Chinese style of "Tiangong Kaiwu", as follows.
This compound has a delicate structure, with pyrrolo [2,1 - f] [1,2,4] triazin as the base nucleus. The pyrrolo ring is in the shape of five elements and has a unique conjugate system, which is like a delicate ring, embedded in the entire structure. The [1,2,4] triazin part is a six-membered heterocyclic ring containing nitrogen, which is arranged by three nitrogen atoms, just like a stable triangular pavilion, giving this compound unique electronic properties.
As for "7-iodine", it indicates that there is an iodine atom at a specific position, that is, the 7th position, where the pyrrolo ring fuses with the [1,2,4] triazin ring. The iodine atom is a unique guest, because its atomic radius is large and the electron cloud is rich, which significantly affects the physical and chemical properties of the compound.
"4-amine" is clearly shown in the 4th position of the base nucleus, connected with an amine group (-NH ²). The amine group acts like a bridge, which can interact with other molecules such as hydrogen bonds, greatly expanding the possibility of chemical reactions and biological activities of this compound.
In summary, the chemical structure of 7-iodopyrrolo [2,1-f] [1,2,4] triazin-4-amine is based on a specific fused heterocyclic ring, with iodine atoms and amine groups. Each part works together to create its unique chemical properties and potential application value.
What are the main uses of 7-iodopyrrolo [2,1-f] [1,2,4] triazin-4-amine
7-Iodopyrrole [2,1-f] [1,2,4] triazine-4-amine is an organic compound. It has a wide range of uses and is often a key intermediate in the creation of new drugs in the field of medicinal chemistry. Due to its unique chemical structure, it has the potential to interact with specific targets in organisms. Therefore, in the process of drug development, many bioactive compounds can be derived by chemical modification, which is expected to become a good medicine for treating various diseases, such as tumors, inflammation and neurological diseases.
In the field of materials science, this compound may also have unique photoelectric properties. The synergistic effect of iodine atom and pyrrolotriazine skeleton in its structure may cause it to exhibit special optical and electrical properties, such as fluorescence emission and charge transport. Therefore, it can be used as a functional material in the development of photovoltaic materials such as organic Light Emitting Diode (OLED) and organic solar cells, providing an opportunity for the development of new photovoltaic devices with high performance and low cost.
Furthermore, in the field of organic synthetic chemistry, 7-iodopyrrole [2,1-f] [1,2,4] triazine-4-amines can be used as an ideal reaction check point due to the activity of iodine atoms. Participate in many organic reactions, such as coupling reactions, etc., and then provide an effective way to construct more complex organic molecular structures, help the development of organic synthetic chemistry, and lay the foundation for the creation of various functional organic materials and fine chemicals.
What are the physical properties of 7-iodopyrrolo [2,1-f] [1,2,4] triazin-4-amine
7-Iodopyrrolio [2,1-f] [1,2,4] triazine-4-amine is an organic compound. Its physical properties are described one by one.
Looking at its appearance, under room temperature and pressure, it may be in a solid state, but the exact color may vary depending on the purity and crystal form. It is common to be white to light yellow powder. This is due to the arrangement and interaction of atoms in the molecular structure, and the characteristics of light scattering and absorption.
As for the melting point, due to the internal force of the compound, its melting point is specific. Intramolecular chemical bonds and intermolecular forces, such as hydrogen bonds, van der Waals forces, etc., jointly maintain the stable arrangement of molecules. When heated, specific energy is required to break this ordered structure. Therefore, the value of the melting point is its inherent property. However, the exact value needs to be determined experimentally and carefully, and it is about a certain temperature range. The range of this range is also affected by the purity of the sample and the test method.
In terms of solubility, the compounds vary in solubility in common organic solvents. In polar organic solvents such as dimethyl sulfoxide (DMSO) and N, N-dimethylformamide (DMF), it may have good solubility, because the polar part of its molecular structure interacts with the polar group of the solvent to form a stable dispersion system. In non-polar organic solvents such as n-hexane and benzene, the solubility may be poor, because the force between the molecule and the non-polar solvent molecule is weak, it is difficult to effectively disperse.
Furthermore, its density is also one of the important physical properties. The density depends on the mass of the molecule and the degree of packing density between the molecules. However, the exact density value needs to be determined by precise experiments. This value is of great significance for the study of its sedimentation and diffusion behavior in different media.
In addition, the vapor pressure of the compound cannot be ignored. The vapor pressure reflects its tendency to change from solid or liquid to gaseous state at a certain temperature. Although the vapor pressure at room temperature is very low, with the increase of temperature, the thermal motion of the molecules intensifies, and the vapor pressure will also increase. This property needs to be carefully considered during its storage and application, with regard to its volatility and stability.
What are the synthesis methods of 7-iodopyrrolo [2,1-f] [1,2,4] triazin-4-amine
The synthesis method of 7-iodopyrrolido [2,1-f] [1,2,4] triazine-4-amine is described in detail today.
First, follow the classic path of chemical synthesis. Select suitable starting materials, such as compounds with pyrrole and triazine structures, and introduce iodine atoms at specific positions through halogenation. The halogenation method is often carried out under suitable reaction conditions with halogenating reagents, such as iodide and appropriate catalysts. The control of reaction conditions is related to success or failure, such as temperature, reaction time, and choice of solvent. If the temperature is too high or side reactions are clustered, if it is too low, the reaction will be slow.
times, you can try the way of organometallic catalysis. Using the unique activity of metal catalysts to guide the reaction to the target product. For example, the coupling reaction catalyzed by palladium can precisely construct a carbon-iodine bond and realize the positioning of iodine atoms on the structure of pyrrole triazine. This path requires fine regulation of factors such as the amount of metal catalysts and the selection of ligands to achieve the ideal yield and selectivity.
In addition, biosynthesis can also be explored. With the help of enzymatic reactions in organisms, simulate the natural synthesis mechanism. Find enzymes with specific catalytic activities, use specific substrates as raw materials, and complete the synthesis in a mild biological environment. Although this method is green and environmentally friendly, the acquisition of enzymes and the construction of reaction systems may pose challenges, requiring in-depth understanding and control of biological systems.
Every step of the synthesis requires careful operation, strict monitoring of the reaction process, and flexible adjustment of strategies according to the characteristics and needs of the reaction to obtain the target product 7-iodopyrrolido [2,1-f] [1,2,4] triazine-4-amine.
7-Iodopyrrolo [2,1-f] [1,2,4] triazin-4-amine is widely used in which fields
7-Iodopyrrole [2,1-f] [1,2,4] triazine-4-amine, this compound has been widely used in medicine, materials science, agricultural chemistry and other fields.
In the field of medicine, it shows unique advantages. Many drug development focuses on the nitrogen-containing heterocyclic structure, 7-iodopyrrole [2,1-f] [1,2,4] triazine-4-amine precisely has this structure, and the introduction of iodine atoms can change the electron cloud distribution and spatial resistance of molecules, affecting their interaction with biological targets. Studies have shown that the compound has the effect of inhibiting proliferation of specific tumor cell lines, and is expected to be developed as a new anti-cancer drug. It interferes with the growth, division and survival of cancer cells by precisely acting on key signaling pathways or protein targets in cancer cells, opening up new opportunities for cancer treatment.
In the field of materials science, due to its special structure, it can be used as a key building block for the construction of functional materials. With its combination with other organic or inorganic materials, materials with unique optical, electrical or mechanical properties can be prepared. For example, in combination with conjugated polymers, the photoelectric properties of materials can be regulated, and they can be used in the field of organic Light Emitting Diodes (OLEDs) or solar cells to improve the luminous efficiency and energy conversion efficiency of devices.
In the field of agricultural chemistry, it can be used as a lead compound for the development of new pesticides. It exhibits inhibitory activity against some crop pests or pathogens. By reasonably modifying its structure, it is expected to develop high-efficiency, low-toxicity and environmentally friendly pesticide products. It can precisely act on the specific physiological processes of pests or pathogens, such as interfering with the transmission of the pest nervous system or inhibiting the synthesis of the cell wall of pathogens, so as to achieve effective prevention and control of crop pests and diseases and ensure the harvest and quality of agricultural production.