7h Pyrrolo 2 3 D Pyrimidin 4 Amine 5 Iodo 7 2 C Methyl B D Ribofuranosyl
Iodobenzene

7h Pyrrolo 2 3 D Pyrimidin 4 Amine 5 Iodo 7 2 C Methyl B D Ribofuranosyl

Fengxi Chemical

Specifications

HS Code

448866

Chemical Formula C12H15IN4O5
Molecular Weight 436.177 g/mol
Iupac Name 5-iodo-7-(2-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Appearance Solid (predicted)
Melting Point No data available
Boiling Point No data available
Solubility Soluble in organic solvents (predicted)
Density No data available
Pka No data available
Logp No data available
Chemical Formula C12H14IN5O4
Molecular Weight 435.18
Chemical Formula C12H14IN5O4
Molecular Weight 421.17
Iupac Name 5-iodo-7-(2-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Chemical Formula C12H14IN5O4
Molecular Weight 433.17
Physical State Solid (predicted)
Appearance Off - white to yellowish solid
Solubility In Water Low solubility (due to its relatively non - polar nature)
Solubility In Organic Solvents Soluble in polar organic solvents like DMSO, DMF
Logp Value Estimated to be around 0 - 1 (lipophilicity indication)
Packing & Storage
Packing 10 grams of 5 - iodo - 7 - (2 - C - methyl - β - D - ribofuranosyl)-7H - pyrrolo[2,3 - d]pyrimidin - 4 - amine in sealed vial.
Storage Store "7h - pyrrolo[2,3 - d]pyrimidin - 4 - amine, 5 - iodo - 7 - (2 - c - methyl - b - d - ribofuranosyl)" in a cool, dry place away from heat and ignition sources. Keep it in a tightly sealed container to prevent exposure to air and moisture, which could potentially degrade the chemical. Avoid storing near incompatible substances.
Shipping The chemical "7H - pyrrolo[2,3 - d]pyrimidin - 4 - amine,5 - iodo - 7 - (2 - C - methyl - β - D - ribofuranosyl)-" will be shipped in specialized, sealed containers. Packaging ensures protection from external factors during transit to maintain chemical integrity.
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7h-pyrrolo[2,3-d]pyrimidin-4-amine,5-iodo-7-(2-c-methyl-b-d-ribofuranosyl)- 7h-pyrrolo[2,3-d]pyrimidin-4-amine,5-iodo-7-(2-c-methyl-b-d-ribofuranosyl)- 7h-pyrrolo[2,3-d]pyrimidin-4-amine,5-iodo-7-(2-c-methyl-b-d-ribofuranosyl)-
General Information
Frequently Asked Questions
What is the chemical structure of 7h-pyrrolo [2,3-d] pyrimidin-4-amine, 5-iodo-7- (2-c-methyl-b-d-ribofuranosyl) -
This is the chemical structure analysis of 7H-pyrrolido [2,3-d] pyrimidine-4-amine, 5-iodine-7- (2-C-methyl - β - D-furan ribosyl). According to its name, it can be disassembled gradually to explain its structure.
"7H-pyrrolido [2,3-d] pyrimidine-4-amine", the core structure is based on pyrimidine, which is a six-membered nitrogen-containing heterocycle with dinitrogen atoms in the meso position. The meaning of pyrrole [2,3-d] is that the pyrrole ring is fused to the pyrimidine ring, and the specific position of the pyrrole ring is connected to the pyrimidine ring, with a hydrogen atom at the 7th position and an amine group at the 4th position.
"5-iodine" indicates the introduction of iodine atoms at the 5th position of the core structure.
"7- (2-C-methyl - β - D-furanosyl) ", which refers to the connection of a glycosyl group at the 7th position, which is a furanosyl, and has a methyl substitution at the 2-C position, and the configuration is β-D. Type β-D indicates that the terminal carbon configuration of the sugar group is β, that is, the hydroxyl group connected to the terminal carbon is on the same side as the hydroxyl methyl group on C5.
In summary, the chemical structure of this compound is composed of a pyrrolidine core containing a specific substituent, which is connected to a specific configuration and a substituted ribofuran group. The position of each substituent is clear and the configuration is specific, which is the whole picture of its chemical structure.
7H-pyrrolo [2,3-d] pyrimidin-4-amine, 5-iodo-7- (2-c-methyl-b-d-ribofuranosyl) - What are the physical properties
5-Iodo-7- (2-C-methyl-β-D-furanribosyl) -7H-pyrrolio [2,3-d] pyrimidine-4-amine, this substance has some physical characteristics. Its shape or crystalline powder, the color is white to yellowish, due to the atomic arrangement and electron cloud distribution in the molecular structure. At room temperature, it exists stably, but when it encounters a hot topic, or due to the intensification of molecular vibration, the chemical bond is weakened and the decomposition reaction is triggered.
When it comes to solubility, in water, its solubility is quite low. Due to the weak molecular polarity of this compound, it is difficult to form sufficient hydrogen bonds with water molecules, like "oil and water are difficult to blend". However, in some organic solvents, such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), the solubility is considerable, because these organic solvents and the compound can form intermolecular forces to disperse them.
Its melting point is relatively high, about a certain temperature range, which is determined by the intermolecular forces and lattice energy. Intermolecular forces and lattice energy are strong, and more energy is required to destroy the lattice and cause the melting point to rise. The density of the substance may be in a certain numerical range, which is related to the molecular weight and the degree of packing. The molecular mass is large and the packing is close, and the density is high. These physical properties are of great significance in the fields of drug development, chemical synthesis, etc., and can provide guidance for the separation, purification, and preparation of preparations.
7H-pyrrolo [2,3-d] pyrimidin-4-amine, 5-iodo-7- (2-c-methyl-b-d-ribofuranosyl) - in which areas is it used
5-Iodine-7- (2-C-methyl - β - D-furan-ribosyl) -7H-pyrrolio [2,3-d] pyrimidine-4-amine, this compound has a wide range of uses and has applications in medicine, biochemistry and other fields.
It can be used in the field of medicine, or can be used to create new antiviral drugs. Due to its unique structure, it has high compatibility with the check point of many key enzymes for virus replication, or can effectively inhibit the synthesis of viral nucleic acid, and has potential inhibitory effects on viruses such as influenza virus and herpes virus. Many examples of drug development in the past have shown that such compounds containing specific heterocycles and glycosyl structures can often become highly effective antiviral drugs after rational modification and modification.
In the field of biochemical research, it can be used as a tool compound to help researchers explore the mysteries of nucleic acid metabolism and enzyme action mechanism in organisms. In past experience, substances with similar structures are often used to label biological macromolecules, track their metabolic pathways, and clarify complex biochemical processes in organisms. For example, in the study of enzyme activity related to DNA and RNA synthesis, the effect of this compound on enzyme activity and nucleic acid synthesis can be observed by introducing it, thereby revealing the fine regulation mechanism of nucleic acid synthesis.
In addition, in the field of agriculture, new plant antiviral agents may be developed to protect crops from viruses and ensure food security and sustainable agricultural development. Throughout history, agricultural production has often been damaged by virus ravages, and the development of new antiviral agents is the key to ensuring agricultural harvests. The unique structure of this compound may give it unique inhibitory activity against plant viruses, bringing new opportunities to the field of agricultural antiviral.
What is the preparation method of 7h-pyrrolo [2,3-d] pyrimidin-4-amine, 5-iodo-7- (2-c-methyl-b-d-ribofuranosyl) -
To prepare 5 - iodine - 7 - (2 - C - methyl - β - D - ribosyl) - 7H - pyrrolio [2,3 - d] pyrimidine - 4 - amine, the method is as follows:
Take the furan ribose derivative first, which is the key starting material. After specific modification, methyl is introduced into its 2 - C position. This step requires fine means to control the reaction conditions, so that methyl is accurately integrated to obtain 2 - C - methyl - β - D - ribose intermediate.
Complex with pyrrolido [2,3-d] pyrimidine-4-amine as the base, through halogenation, the iodine atom is introduced at the 5th position. This halogenation method requires the selection of suitable halogenation reagents, and the influence of temperature, solvent and other factors to make the iodine atom smoothly added to the target position to obtain 5-iodine-7H-pyrrolido [2,3-d] pyrimidine-4-amine intermediate.
Then the above two intermediates meet and undergo a condensation reaction to combine 5-iodine-7- (2-C-methyl - β - D-furan-ribosyl) -7H-pyrrolio [2,3-d] pyrimidine-4-amine. This condensation process involves finding a high-efficiency condensation reagent and controlling the reaction environment to increase the yield and purity of the product. After the reaction is completed, it is separated and purified by methods such as column chromatography and recrystallization to remove impurities and obtain a pure product.
Throughout the preparation process, each step requires careful observation of the reaction details and precise control of the conditions before the target compound can be obtained.
What is the market outlook for 7h-pyrrolo [2,3-d] pyrimidin-4-amine, 5-iodo-7- (2-c-methyl-b-d-ribofuranosyl) -?
There are now 7h - pyrrolo [2,3 - d] pyrimidin - 4 - amine, 5 - iodo - 7 - (2 - c - methyl - b - d - ribofuranosyl), and its market prospects are related to many aspects.
Looking at its pharmaceutical field, this compound may have unique biological activities. The combination of iodine atoms and specific sugar groups in the Gain structure may give it the ability to target specific biomolecules. Nowadays, pharmaceutical research and development is keen to find such compounds with precise targets in order to develop new drugs with good efficacy and few side effects. If this substance exhibits significant affinity and regulatory activity for certain disease-related proteins or receptors in pharmacological experiments, it is expected to open the door to the development of new drugs, and the market potential is limitless.
In the scientific research reagent market, due to its unique chemical structure, it can provide novel research tools for researchers in the fields of organic synthetic chemistry, medicinal chemistry, etc. Researchers often need compounds with different structures to explore reaction mechanisms and optimize synthesis routes. If this compound can help scientific research and promote the birth of new reactions and methods, it will surely occupy a place in the scientific research reagent market and be demanded by many laboratories.
However, its market prospects also face challenges. The process of synthesizing this compound may be complex and costly, which is a major obstacle. If the synthesis route cannot be optimized and the production cost can be reduced, even if its biological activity is excellent, it will be difficult to be widely used in the market. And the road to drug development is long, and it needs to go through multiple rounds of rigorous clinical trials before it can be approved for marketing. This process is not only time-consuming, but also expensive. If the clinical trial results are not as expected, the early efforts may be in vain.
Overall, 7h - pyrrolo [2,3 - d] pyrimidin - 4 - amine, 5 - iodo - 7 - (2 - c - methyl - b - d - ribofuranosyl) has potential opportunities in the field of medicine and scientific research due to its unique structure, but it also needs to overcome problems such as synthesis costs and R & D risks in order to emerge in the market and gain development space.