What is the chemical structure of 7h-pyrrolo [2,3-d] pyrimidine, 7- [3,5-bis-o- [ (2,4-dichlorophenyl) methyl] -2-c-methyl-b-d-ribofuranosyl] -4-chloro-5-iodo-

7 - [3,5 - bis - O - [ (2,4 - dichlorophenyl) methyl] - 2 - C - methyl - β - D - ribofuryl] - 4 - chloro - 5 - iodine - 7H - pyrrolido [2,3 - d] pyrimidine is a complex organic compound. According to its name, its core structure is 7H - pyrrolido [2,3 - d] pyrimidine.

Its 7th position is connected to a substituent containing a furan ribosyl group, which has been modified to be connected to an O - [ (2,4 -dichlorophenyl) methyl] group at the 3rd and 5th positions, and has a methyl substitution on the 2nd carbon atom. At the same time, at the 4th and 5th positions of the pyrimidine ring, chlorine atoms and iodine atoms are connected, respectively. The structure of this compound is exquisitely designed, and the combination of different groups endows it with unique chemical properties, which may be of important value in the study of specific chemical reactions and biological activities.

What are the physical properties of 7h-pyrrolo [2,3-d] pyrimidine, 7- [3,5-bis-o- [ (2,4-dichlorophenyl) methyl] -2-c-methyl-b-d-ribofuranosyl] -4-chloro-5-iodo-

7 - [3,5 - bis - O - [ (2,4 - dichlorophenyl) methyl] - 2 - C - methyl - β - D - furanyl] - 4 - chloro - 5 - iodine - 7H - pyrrolido [2,3 - d] pyrimidine, this is a complex organic compound. Its physical properties are unique and related to many fields of chemistry.

First, the appearance is mentioned, or it is white to light yellow crystalline powder. The melting point of this compound is one of its important physical properties. Due to the interaction between atoms and chemical bonds in the molecular structure, its melting point is in a specific range, but the specific value needs to be accurately determined by experiments.

In terms of solubility, it may exhibit a certain solubility in organic solvents such as dichloromethane and chloroform. This is due to the interaction forces between some groups and organic solvent molecules in the molecular structure of the compound, such as van der Waals force, hydrogen bond, etc., which help it dissolve. However, its solubility in water may be poor. Due to the large proportion of hydrophobic groups in the structure, it is difficult to form effective interactions with water molecules.

Its density is also a key physical property. Due to the fixed type, number and spatial arrangement of atoms in the molecule, its density is fixed. The density affects the settling and floating behavior of the compound in different media, which is of great significance in chemical separation, purification and other operations.

Furthermore, the stability of the compound is also an important physical property. Some chemical bonds in the structure, such as carbon-chlorine bonds and carbon-iodine bonds, may break under specific conditions, which affects its stability. Factors such as high temperature, light, and specific pH environment may trigger such changes.

The physical properties of this compound are of great significance in the fields of medicinal chemistry and organic synthesis chemistry. In medicinal chemistry, properties such as solubility and stability affect the absorption, distribution, metabolism and excretion of drugs; in organic synthesis chemistry, properties such as melting point and density assist the separation, purification and identification of compounds.

What is the synthesis method of 7h-pyrrolo [2,3-d] pyrimidine, 7- [3,5-bis-o- [ (2,4-dichlorophenyl) methyl] -2-c-methyl-b-d-ribofuranosyl] -4-chloro-5-iodo-

To prepare 7 - [3,5 - bis - O - [ (2,4 - dichlorophenyl) methyl] - 2 - C - methyl - β - D - furanosyl] - 4 - chloro - 5 - iodine - 7H - pyrrolido [2,3 - d] pyrimidine, the method is as follows:
First, a suitable starting material needs to be taken, which should contain the necessary fragments for constructing the core structure of the target molecule. For example, select a specific substituent of the furanosyl derivative and a precursor containing pyrrolido pyrimidine parent nucleus.
At the beginning of the reaction, perform protective group operation on the furanribose part. Select appropriate protective reagents to react with (2,4-dichlorophenyl) methylation reagents at 3,5 positions to form corresponding protective structures. This step aims to precisely locate the modification and protect specific hydroxyl groups to avoid unnecessary side reactions in subsequent reactions.
Then, the protected furanribose derivative is linked to the 4-chloro-5-iodine-7H-pyrrolido [2,3-d] pyrimidine parent nucleus. This linking reaction needs to be carried out under specific reaction conditions, such as selecting suitable solvents, bases and catalysts, to promote the bonding between the two. The solvent is often an anhydrous organic solvent to ensure the purity of the reaction system; the alkali can help activate the reaction check point; the catalyst accelerates the reaction process, so that the reaction can be carried out efficiently, and the connection between the sugar group and the pyrimidine parent nucleus is achieved.
During the reaction process, suitable analytical methods need to be used to monitor, such as thin layer chromatography (TLC), to grasp the reaction progress in real time, so as to adjust the reaction conditions in time. When the reaction reaches the desired level, the reaction is terminated and post-treatment is carried out. The post-treatment steps include extraction and washing of the reaction solution to remove impurities; and then purification methods such as column chromatography to separate the pure target product. During column chromatography, the appropriate fixed phase and mobile phase are selected to achieve high-efficiency separation according to the polarity difference between the product and the Thus, after careful operation in multiple steps, 7 - [3,5 - bis - O - [ (2,4 - dichlorophenyl) methyl] - 2 - C - methyl - β - D - furanyl] - 4 - chloro - 5 - iodine - 7H - pyrrolido [2,3 - d] pyrimidine can be obtained.

What are the application fields of 7h-pyrrolo [2,3-d] pyrimidine, 7- [3,5-bis-o- [ (2,4-dichlorophenyl) methyl] -2-c-methyl-b-d-ribofuranosyl] -4-chloro-5-iodo-

7 - [3,5 - bis - O - [ (2,4 - dichlorophenyl) methyl] - 2 - C - methyl - β - D - furan ribosyl] - 4 - chloro - 5 - iodine - 7H - pyrrolido [2,3 - d] pyrimidine This compound is used in medicine or in the field of antivirus. Looking at its structure, it is complex and delicate. Its ribosyl, halogen and pyrimidine structures may give it the ability to interact with key viral proteins to prevent virus replication and reproduction, such as anti-RNA viruses, or by binding to viral polymerase, interfering with its normal function.

In the context of anti-tumor, or play a role. Abnormal proliferation of tumor cells, this compound may target tumor cell-specific proteins, break their proliferation signaling pathways, and inhibit tumor growth. If it acts on some kinases, inhibit their phosphorylation process, cause tumor cell cycle stagnation and induce apoptosis.

Furthermore, in the realm of immune regulation, it may affect immune cell activity. Its unique structure may interact with immune cell surface receptors, regulate immune cytokine secretion, and help the body balance the immune response. It has potential value in the treatment of autoimmune diseases or immunocompromised diseases. However, its specific effectiveness still needs to be verified by multiple experiments, from the cellular level, animal models to clinical trials, in order to clarify its exact efficacy and application prospects in various fields.

7H-pyrrolo [2,3-d] pyrimidine, 7- [3,5-bis-o- [ (2,4-dichlorophenyl) methyl] -2-c-methyl-b-d-ribofuranosyl] -4-chloro-5-iodo-

The writing style of "Tiangong Kaiwu" is simple and concise, and it is good to tell the truth from the situation of things and the outline of things. Jin Yan said "7h - pyrrolo [2,3 - d] pyrimidine, 7- [3,5 - bis - o - [ (2,4 - dichlorophenyl) methyl] - 2 - c - methyl - b - d - ribofuranosyl] - 4 - chloro - 5 - iodo -" This product, its market prospect, is difficult to hide.

Looking at the current world, the pharmaceutical and chemical industries are booming, and the demand for fine chemicals is booming. However, this substance is uncommon, it is a special organic compound, which is not a genus of ordinary daily use. The method of synthesis involves complicated steps, precise control, and the raw materials may be rare, the process may be harsh, which all hinder its mass production.

If it is used, or if there is a first-line opportunity in the field of cutting-edge drug research and development, it is expected to become a sharp blade to overcome difficult diseases in order to explore the leading structure of new drugs. However, the road to creating new drugs is long and dangerous. From the initial appearance of compounds to the use of finished drugs, it needs to go through many barriers. Pharmacological research, toxicological testing, and clinical trials are all like mountains and mountains, which are difficult to overcome.

Furthermore, the unknown market demand is also a major problem. Although there may be sporadic explorations in the field of scientific research, the scale is limited and it is difficult to become a big market. If there is no major breakthrough, it will trigger industry changes, or it will be difficult to see widespread application and large demand. Therefore, its market prospect is like a boat in the fog, the direction is unknown, and the road ahead is difficult. It still takes time and opportunity to break this situation and open a new chapter.