Boc Iodo Ala Ome

Alas, this Boc - β - iodo-ala-ome, is the abbreviation of a compound in organic chemistry. Among them, Boc, tert-butoxycarbonyl, is often used as the protective group of the amino group, because it can stabilize the amino group under many reaction conditions, and can be gently removed when needed. Beta-iodo, shows that the iodine atom is attached to the carbon at the beta position. Ala, abbreviation for alanine, is a member of the amino acid family. And ome, represents methoxy, the carboxyl group of alanine in the structure of this compound forms an ester with the methoxy group.
Looking at this compound, its overall structure contains an amino group protected by Boc, the beta position is connected to the alanine main chain of the iodine atom, and the carboxyl group is an ester structure formed by the methoxy group. This structure has unique significance in organic synthesis. Iodine atoms can be used as active check points for nucleophilic substitution, coupling reactions, etc., to help construct complex organic molecules; Boc-protected amino groups can ensure that the amino groups are not damaged in multi-step reactions, and the reaction check point and sequence can be precisely regulated. The ester group structure can also be transformed by hydrolysis in subsequent reactions to obtain compounds with different functions. Its chemical structure is exquisite, and it can be deeply explored and applied in the field of organic chemistry.

Boc-β-iodo-ala-ome is an important compound in organic synthesis. Its main uses are about three.
First, it is often used as a key building block in the synthesis of peptide compounds. In the synthesis of peptides, it is necessary to precisely control the connection order and reaction conditions of each amino acid. Boc-β-iodo-ala-ome has a unique structure, in which the Boc group can protect the amino group from unnecessary participation in side reactions during the reaction process and ensure that the reaction proceeds in the desired direction. The presence of iodine atoms can be used as an activity check point. By means of coupling reactions, it can be connected with other molecules containing specific functional groups to build a complex peptide chain structure.
Second, it also has important functions in the field of drug research and development. The core structure of many drug molecules contains similar amino acid derivative fragments. With this compound as the starting material, through various chemical modifications and structural optimization, new drug molecules can be created. Its iodine atom can be introduced into other functional groups through chemical transformation, changing the physical and chemical properties of drug molecules, such as solubility and fat solubility, etc., thereby optimizing the pharmacokinetics and pharmacodynamics of drugs.
Third, it also has potential applications in materials science. Through ingenious design of reactions, Boc-β-iodo-ala-ome is involved in the construction of polymer materials. Through its polymerization reaction with other monomers, specific functions can be imparted to the material. For example, the functional groups contained in it can be used to make the surface of the material biocompatible, or to endow the material with responsiveness to meet the needs of different fields for the special properties of the material.

To prepare Boc-β-iodo-ala-ome, the method is as follows:
Take beta-alanine first, use tert-butoxycarbonyl (Boc) as the protective group, and react with di-tert-butyl dicarbonate in a suitable temperature and alkaline environment to obtain Boc-β-alanine. This step is intended to protect the amino group and prevent it from generating miscellaneous side reactions in subsequent reactions.
The Boc-β-alanine is co-placed in an organic solvent with iodine reagents, such as N-iodosuccinimide (NIS) and an appropriate amount of catalyst, and the temperature control reaction makes the beta site successfully introduce iodine atoms to obtain Boc-β-iodo-alanine. This step requires precise temperature control and reaction time. Due to the high iodine reactivity, it is easy to overreact. After
, the obtained Boc-β-iodo-alanine is co-heated with methanol and catalytic concentrated sulfuric acid or p-toluenesulfonic acid, and the esterification reaction is carried out to produce Boc-β-iodo-ala-ome. This step completes the conversion of carboxyl groups into methyl ester groups, and the reaction needs to neutralize the acid. After extraction, drying, column chromatography and other purification methods, pure Boc-β-iodo-ala-ome can be obtained.
The oil bath temperature, material ratio and reaction time must be strictly controlled in each step of the reaction, and the intermediates and products need to be characterized in detail by infrared spectroscopy and nuclear magnetic resonance to ensure that the structure is correct and the purity is up to standard.

Boc-β-iodo-ala-ome is an important compound in organic synthesis. When storing it, many matters need to be paid attention to.
bear the brunt, and temperature control is crucial. This compound may be unstable with temperature, so it should be stored in a low temperature environment, often refrigerated in the refrigerator, about 2-8 ° C, so that it can slow down its possible decomposition or deterioration.
Second, the humidity should not be underestimated. Too high humidity, or adverse reactions such as hydrolysis, cause damage to its structure and quality. Therefore, when placed in a dry place, it can be accompanied by a desiccant to keep the environment dry.
Furthermore, it is also a priority to avoid light. Light may stimulate its chemical reaction, causing it to deactivate or deteriorate. It should be hidden in an opaque container, such as a brown bottle, and placed in a dark place.
In addition, avoid contact with incompatible substances. Because of its specific chemical properties, it may react violently when encountering certain compounds, damaging itself and causing danger. Therefore, it is necessary to know its chemical properties in detail and store it in isolation from other substances.
In addition, the storage place should be well ventilated. If stored in a closed and airtight place, in case it evaporates or decomposes to produce gas, it can cause dangerous accumulation.
In summary, in order to properly store Boc-β-iodo-ala-ome, it is necessary to carefully manage temperature, humidity, light, contact objects, and ventilation in order to ensure its quality and stability, and achieve the desired effect in subsequent use.

Boc-β-iodo-ala-ome is a key compound in the field of organic synthesis. However, its market price is difficult to determine, because many factors can cause it to fluctuate.
The first to bear the brunt is the cost of raw materials. It is common sense that if the starting materials required to synthesize this compound are scarce or difficult to prepare, the price must be high. For example, if the key raw materials require complicated purification processes or are only available in specific regions, the raw material price will be high, and the cost of Boc-β-iodo-ala-ome will also rise.
Furthermore, the difficulty of the synthesis process has a significant impact. If the synthesis steps are lengthy, multiple reactions are required, and the reaction conditions of each step are harsh, the equipment and technical requirements are extremely high, during which manpower and material resources are consumed, and the product price is naturally high. On the contrary, if the process is simple and efficient, the cost can be reduced.
The state of market supply and demand also affects its price. If this compound is in strong demand in pharmaceutical research and development, material science and other fields, but the supply is limited, according to the principle of supply and demand, the price is bound to rise. If supply exceeds demand, the price may decline.
In addition, the purity and quality of the products supplied by different suppliers are different, and the price will also be different. High-purity products, due to high purification costs, sell at high prices.
In the past, the price of such compounds may vary from time to time, ranging from a few hundred yuan per gram to a few thousand yuan. However, to know the exact price at the moment, you need to consult the chemical raw material supplier in detail, or check it carefully on the professional chemical trading platform.