What is the chemical structure of (E) -6-iodine-3- (2- (pyridin-2-yl) vinyl) -1- (tetrahydro-2h-pyran-2-yl) -1h-indazole
(E) -6-Iodine-3- (2- (pyridine-2-yl) vinyl) -1- (tetrahydro-2H-pyran-2-yl) -1H-indazole, the chemical structure of this compound, let me tell you in detail.
Looking at its name, it can be seen that this is an organic compound containing the core structure of indazole. "1H-indazole", this is the main skeleton of the compound, just like the beam of a building. In the 1st position, there is a " (tetrahydro-2H-pyran-2-yl) " group, which is composed of a six-membered cyclic structure containing one oxygen atom. The part of the tetrahydropyran has four saturated carbon atoms, just like a delicate ring fastened to the indazole skeleton.
And in the 3rd position, there is " (2- (pyridine-2-yl) vinyl) ", pyridine is a nitrogen-containing hexamembered aromatic ring with aromatic properties. Pyridine-2-yl is connected to the indazole through vinyl, and the double bond of the vinyl gives this part certain rigidity and conjugation properties.
Furthermore, the 6-position "iodine" atom is connected, and the iodine atom is relatively large. Its introduction will significantly affect the physical and chemical properties of the compound, such as increasing the polarity of the molecule and affecting the steric resistance.
The structure of this compound, the parts are connected to each other, and the synergistic effect jointly determines its unique chemical and physical properties. It may have specific applications and research value in organic synthesis, medicinal chemistry and other fields.
What are the physical properties of (E) -6-iodine-3- (2- (pyridin-2-yl) vinyl) -1- (tetrahydro-2h-pyran-2-yl) -1h-indazole
(E) -6-Iodine-3- (2- (pyridine-2-yl) vinyl) -1- (tetrahydro-2H-pyran-2-yl) -1H-indazole This substance has critical physical properties and is related to many uses and characteristics.
Looking at its morphology, it usually takes the shape of a solid state under normal conditions, which is determined by the intermolecular force, resulting in the close arrangement of molecules to form a stable solid structure. As for the color, it is mostly white or off-white powder. This pure color also reflects the relative simplicity and purity of its chemical structure.
When it comes to melting point, the melting point of this substance is measured at a specific temperature range. This temperature is the critical value for its conversion from solid to liquid. This property can not only be used to identify the substance, but also is of great significance for its processing and application under specific conditions. If the temperature approaches the melting point, its physical state will change, or it will affect subsequent chemical reactions and material properties.
Solubility is also one of the important physical properties. In common organic solvents, such as ethanol and dichloromethane, it exhibits certain solubility. In ethanol, under moderate temperature and stirring conditions, it can be partially dissolved to form a uniform solution. In water, its solubility is relatively poor, because the molecular structure of the substance is mainly non-polar parts, and the interaction with water molecules is weak. This difference in solubility needs to be carefully considered when extracting, separating and preparing related preparations.
In addition, the density of the substance is also an important physical parameter. Although the exact value needs to be determined by professional instruments, its approximate range can be inferred based on its chemical structure and similar compounds. Density is related to its distribution and precipitation characteristics in different media. In application scenarios involving mixed systems, such as drug suspensions and composites, the influence of density cannot be ignored.
The physical properties of (E) -6-iodine-3- (2- (pyridine-2-yl) vinyl) -1- (tetrahydro-2H-pyran-2-yl) -1H-indazole are indispensable basic information in many fields such as chemical synthesis, materials science and drug development, and play a key guiding role in in-depth exploration of its chemical behavior and practical applications.
What is the synthesis method of (E) -6-iodine-3- (2- (pyridin-2-yl) vinyl) -1- (tetrahydro-2h-pyran-2-yl) -1h-indazole
To prepare (E) -6-iodine-3- (2- (pyridine-2-yl) vinyl) -1- (tetrahydro-2H-pyran-2-yl) -1H-indazole, the method is as follows:
First, various raw materials need to be prepared, such as iodine-containing compounds, reagents with pyridine-2-yl vinyl structures, tetrahydro-2H-pyran-2-yl related reactants and 1H-indazole basic raw materials.
In a clean and dry reactor, place the 1H-indazole base material into it according to the appropriate ratio, and then slowly add the iodine-containing compound. During this process, attention should be paid to the regulation of the reaction temperature to maintain it in an appropriate range, or under moderate heating and supplemented with stirring, the two can be fully reacted, so that the iodine atom is precisely connected to the indazole position No. 6.
After the iodine substitution reaction is completed, the pre-prepared pyridine-2-yl vinyl structure reagent is added dropwise to the reaction system. This step of the reaction may require the introduction of a specific catalyst to accelerate the reaction rate, and at the same time, close attention should be paid to the pH of the reaction environment and timely adjustment with a buffer to ensure that the reaction can proceed smoothly towards the direction of generating the target product. Then, the tetrahydro-2H-pyran-2-yl related reactant was added, and through a series of reaction steps, it was combined with the reacted intermediate product to construct a complete (E) -6-iodine-3- (2- (pyridine-2-yl) vinyl) -1- (tetrahydro-2H-pyran-2-yl) -1H-indazole molecular structure.
At the end of the reaction, suitable separation and purification methods, such as column chromatography, recrystallization method, etc., are used to separate the target product from the reaction mixture system, remove impurities, and obtain a pure (E) -6-iodine-3- (2- (pyridine-2-yl) vinyl) -1- (tetrahydro-2H-pyran-2-yl) -1H-indazole product.
What are the application fields of (E) -6-iodo-3- (2- (pyridin-2-yl) vinyl) -1- (tetrahydro-2h-pyran-2-yl) -1h-indazole
(E) -6-iodine-3- (2- (pyridine-2-yl) vinyl) -1- (tetrahydro-2H-pyran-2-yl) -1H-indazole is useful in the fields of medicine and chemical industry.
In the field of medicine, it may be a key intermediate for the development of new anti-cancer drugs. The structure of Gainindazole and pyridine is commonly found in many bioactive molecules. The research and development of many anti-cancer drugs often use specific structures to interact with cancer cell targets to inhibit cancer cell proliferation and induce cancer cell apoptosis. The unique structure of (E) -6-iodine-3- (2- (pyridine-2-yl) vinyl) -1- (tetrahydro-2H-pyran-2-yl) -1H-indazole may accurately act on specific proteins or signaling pathways of cancer cells, providing the possibility for the creation of new anti-cancer drugs.
In the chemical industry, it can be used as an important building block for organic synthesis. Organic synthesis aims to build complex organic molecules, the multi-functional structure of this compound, so that it can participate in a variety of chemical reactions. With the reactivity of iodine atoms, vinyl, pyranyl and other functional groups, the modification and expansion of molecules can be realized, and polymer materials and functional dyes with special properties can be synthesized. Such as polymerization with specific monomers, or polymer with special optical and electrical properties can be prepared, which can be used in the field of optoelectronic materials.
What is the market outlook for (E) -6-iodo-3- (2- (pyridin-2-yl) vinyl) -1- (tetrahydro-2h-pyran-2-yl) -1h-indazole?
(E) -6-iodine-3- (2- (pyridine-2-yl) vinyl) -1- (tetrahydro-2H-pyran-2-yl) -1H-indazole, this compound in today's market prospects, just like the changing sky, it is difficult to see the whole picture, but there are traces to follow.
View this compound, its use in the field of pharmaceutical research and development, or the opportunity to emerge. Geinindazole, pyridine and other structural units are often the key building blocks for the creation of new drugs. In today's pharmaceutical market, there is a hunger for innovative drugs with excellent efficacy and mild side effects. The unique molecular structure of this compound may be able to fit specific targets, providing new possibilities for conquering difficult diseases such as cancer and neurological diseases. It is like the key to unlocking unknown treasures.
However, its market journey is not smooth. The road of new drug research and development is like a jungle full of thorns. It needs to go through many tests of pre-clinical research, such as pharmacodynamics, pharmacokinetics and safety evaluation. And in the clinical research stage, it also requires a lot of manpower, material resources and time. Only by successfully crossing these hurdles can we enter the market.
Furthermore, in the field of chemical materials, this compound may also play its unique role. Its special chemical properties can be used to synthesize polymer materials with excellent performance, or as a key component of catalysts, contributing to the efficiency improvement and process optimization of chemical production.
However, the fierce competition in the market is also like a storm, surging. The same or alternative compounds emerge one after another, like a thousand sails racing. If you want to gain a firm foothold in the market, you not only need to have unique performance advantages, cost control, production scale expansion and other factors, but also like the two ends of the balance. A slight imbalance may affect the ups and downs of the market.
To sum up, (E) -6-iodine-3- (2- (pyridine-2-yl) vinyl) -1- (tetrahydro-2H-pyran-2-yl) -1H-indazole has unlimited potential in the field of medicine and chemical industry, but if it wants to bloom, it needs to overcome many difficulties and break through many difficulties in order to gain a place in the vast world of the market.