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What is the chemical structure of Ethyl 2- (4-chloro-5-iodo-2-methoxyphenyl) amino) acetate
Ethyl 2- (4-chloro-5-iodo-2-methoxyphenyl) amino) acetate is an organic compound, and its chemical structure can be analyzed according to the following method.
First view of "Ethyl", this is the ethyl group, that is, the group of -C ² H, which is attached to a specific part of the molecule.
In "2- (4-chloro-5-iodo-2-methoxyphenyl) amino) acetate", "acetate" epiacetate group, that is, CH 🥰 COO -, and "2 -" represents the relative position of the carbon atom connected to the carbonyl group in this acetate group to the subsequent group.
" (4-chloro-5-iodo-2-methoxyphenyl) amino" part, "phenyl" is a phenyl group, that is, C H. "4-chloro-5-iodo-2-methoxy" Epiphenyl has a chlorine atom (-Cl) substitution at the 4th position, an iodine atom (-I) at the 5th position, and a methoxy group (-OCH 🥰) at the 2nd position. "Amino" is an amino group (-NH ²), which is connected to the above-mentioned substituted phenyl group, and this amino-containing substituted phenyl group is connected to the carbon atom at the 2nd position of the acetate group.
In summary, the chemical structure of the compound is: ethyl is connected to the oxygen atom of the acetate group, and the 2-position carbon atom of the acetate group is connected to the (4-chloro-5-iodine-2-methoxyphenyl) amino group. Its structure contains elements such as carbon, hydrogen, oxygen, nitrogen, chlorine, iodine, etc. Each atom is connected according to the above substitution relationship to form a unique organic molecular structure, showing specific chemical properties and reactivity.
What are the main uses of Ethyl 2- (4-chloro-5-iodo-2-methoxyphenyl) amino) acetate
Ethyl 2- (4-chloro-5-iodo-2-methoxyphenyl) amino) acetate is an organic compound with a wide range of uses and applications in many fields.
In the field of medicinal chemistry, this compound may be used as an important intermediate for the synthesis of drug molecules with specific biological activities. Because its structure contains halogen atoms such as chlorine and iodine, as well as groups such as methoxy and aminoacetate, these structural characteristics may endow drugs with unique physicochemical properties and biological activities, such as enhancing the ability of drugs to bind to targets, affecting the metabolic process of drugs, and then contributing to the treatment of specific diseases, such as antibacterial, anti-inflammatory, anti-tumor drug development.
In the field of materials science, Ethyl 2- (4-chloro-5-iodo-2-methoxyphenyl) amino) acetate may participate in the preparation of some functional materials. Due to its special structure, it may be able to regulate the optical and electrical properties of materials. For example, in organic optoelectronic materials, its halogen atoms and aromatic groups may affect the electron transport properties and luminous efficiency of materials, and then be used in the development of organic Light Emitting Diodes (OLEDs), solar cells and other materials.
In the field of organic synthetic chemistry, this compound, as an intermediate, can carry out various organic reactions, such as nucleophilic substitution reactions, coupling reactions, etc. by means of its different activity checking points, to construct more complex organic molecular structures, providing an important structural basis and reaction substrate for the research and development of organic synthetic chemistry, and helping scientists create more new organic compounds with special properties.
What are the synthesis methods of Ethyl 2- (4-chloro-5-iodo-2-methoxyphenyl) amino) acetate
To prepare Ethyl 2- ((4 - chloro - 5 - iodo - 2 - methoxyphenyl) amino acid) acetate, the method of organic synthesis is often followed. The first step is to prepare starting materials, such as 4 - chloro - 5 - iodo - 2 - methoxyaniline and ethyl chloroacetate, which are the basis for synthesis.
One method is to first react 4 - chloro - 5 - iodo - 2 - methoxyaniline with ethyl chloroacetate in the presence of bases. Bases, such as potassium carbonate and sodium carbonate, can promote nucleophilic substitution reactions. The solvent for the reaction can be selected from N, N-dimethylformamide (DMF), dimethylsulfoxide (DMSO) and other aprotonic polar solvents, because it is soluble in the substrate and alkali, and the reaction is favorable. Under this condition, the amine nucleophilic attacks the carbonyl carbon of ethyl chloroacetate, and the chlorine leaves, and then becomes the precursor of the target product. After the reaction is completed, the reaction is quenched with water. The product is often extracted with an organic solvent, such as ethyl acetate, dichloromethane, etc., and then purified by column chromatography or recrystallization to obtain pure Ethyl 2- ((4-chloro-5-iodo-2-methoxyphenyl) amino acid) acetate.
Another method can be used to prepare 4-chloro-5-iodo-2-methoxyaniline into its corresponding sodium salt or potassium salt to enhance its nucleophilicity, and then react with ethyl chloroacetate. The method of salt production can be made by reacting sodium or potassium hydride with amine. This salt reacts with ethyl chloroacetate in a suitable solvent, and the target product can also be obtained. Subsequent treatment is as before, after quenching, extraction, and purification to obtain a pure product.
In addition, phase transfer catalysis can also be used. A phase transfer catalyst, such as tetrabutylammonium bromide, is added to the reaction system. This agent can help the base of the aqueous phase to contact the substrate of the organic phase, so that the reaction can be carried out under milder conditions. The reaction raw material is in the water-organic mixed solvent, and the nucleophilic substitution reaction occurs under the action of the phase transfer catalyst and the base. After the reaction is completed, Ethyl 2- ((4-chloro-5-iodo-2-methoxyphenyl) amino) acetate is obtained according to the conventional separation and purification method.
What are the physical properties of Ethyl 2- (4-chloro-5-iodo-2-methoxyphenyl) amino) acetate
Ethyl 2- (4-chloro-5-iodo-2-methoxyphenyl) amino) acetate is an organic compound, and its physical properties are of great research value.
Looking at its properties, under normal circumstances, this compound may be in a solid state. Due to the interaction of benzene ring, halogen atom and ester group in the molecular structure, the intermolecular force is enhanced, and it is easy to form a regular arrangement, so it presents a solid state.
In terms of melting point, due to the presence of halogen atoms such as chlorine and iodine in the molecule, the atomic weight is large, and the benzene ring structure also enhances the intermolecular force, so that its melting point may be in a relatively high range. However, the exact value needs to be accurately determined by experiments.
In terms of solubility, due to the fact that the molecule contains lipophilic groups such as ethoxy ester group and methoxy group, it may have certain solubility in common organic solvents such as ethanol, ether, and dichloromethane. However, because the molecule as a whole is not highly polar, the solubility in water may be poor.
In terms of density, the presence of halogen atoms increases the molecular weight, and it is speculated that its density is larger than that of water. Due to the large relative atomic mass of chlorine and iodine atoms, the mass of the compound is higher in unit volume.
Volatility, due to the strong intermolecular force, containing benzene rings and polyatomic functional groups, its volatility should be low, and it is not easy to evaporate from liquid to gaseous state. The physical properties of Ethyl 2- (4-chloro-5-iodo-2-methoxyphenyl) amino) acetate are synergistically affected by various groups in its molecular structure, and exhibit specific characteristics such as melting point, solubility, density and volatility.
What is the market outlook for Ethyl 2- (4-chloro-5-iodo-2-methoxyphenyl) amino) acetate?
Ethyl 2- (4-chloro-5-iodo-2-methoxyphenyl) amino) acetate, an organic compound, is often found in the fields of medicinal chemistry and organic synthesis. Its market prospects are worth exploring. From the perspective of "Tiangong Kaiwu", it can be analyzed from various aspects.
The availability of raw materials is the primary consideration. The availability of raw materials such as 4-chloro-5-iodine-2-methoxy aniline and ethyl chloroacetate required for the preparation of this product is related to cost and production scale. If the raw materials are easily available and the supply is stable, as "Tiangong Kaiwu" said, "Where bamboo paper is made, it occurs in the south, while Fujian Province is unique in its prosperity, and the production of rattan bamboo is inexhaustible." The availability of raw materials lays the foundation for large-scale production, and the market prospect is also broader.
The simplicity and efficiency of the synthesis process also affect its market prospects. If the synthesis steps are complicated and the yield is low, it is like the ancient papermaking process. If the process is cumbersome and time-consuming, the cost will be high, and it will be unfavorable to market competition. On the contrary, if the process is simple and efficient, such as the refining method recorded in "Tiangong Kaiwu", "Where iron is separated and cooked, it is raw when it is not fried, and it is cooked when it is fried. When it is raw and cooked, it is steel when it is refined", which can effectively improve the output and quality, and can attract more manufacturers to invest in production and expand the market.
The number of application fields also affects its market prospects. In the field of medicine, if it can be used as a key intermediate to synthesize drugs with significant curative effect and great market demand, just as in "Tiangong Kaiwu", good materials can be used well and can cure diseases and save people, then the market demand will be extremely considerable. In addition, if it can be used as a unique building block in organic synthesis to create novel functional materials, it can also open up new markets.
The competitive situation should not be underestimated. If there are many similar or alternative compounds in the market and the competition is fierce, it is necessary to highlight its own advantages, such as excellent performance and affordable prices, in order to gain a firm foothold in the market. Just like the competition between different craftsmen in "Tiangong Kaiwu", the best will win.
Policies and regulations also have an impact. If environmental protection, safety and other regulations set restrictions on its production and use, it must be strictly followed to ensure compliance with production and sales, so as to maintain the stable development of the market.
In summary, the market prospect of Ethyl 2- (4-chloro-5-iodo-2-methoxyphenyl) amino) acetate is affected by many factors such as raw materials, processes, applications, competition and regulations. Only by properly responding to all aspects can it be unimpeded in the market.