Ethyl 2-Bromo-5-Iodobenzoate

Fengxi Chemical

Specifications

HS Code	217202
Chemical Formula	C9H8BrIO2
Molar Mass	359.967 g/mol
Appearance	Solid (usually off - white to light - colored powder)
Melting Point	Typically in the range where it starts to change state from solid to liquid (exact value may vary depending on purity)
Solubility In Water	Insoluble in water (organic compound with non - polar and hydrophobic parts)
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, chloroform, ethyl acetate
Reactivity	Reactive due to presence of bromine and iodine, can undergo substitution reactions
Hazard	May be harmful if swallowed, inhaled or in contact with skin; bromine and iodine - containing compounds can be irritants
Chemical Formula	C9H8BrIO2
Molar Mass	359.967 g/mol
Appearance	Typically a solid (description may vary based on purity and preparation)
Physical State At Room Temperature	Solid
Solubility In Water	Insoluble (due to non - polar nature of the organic backbone)
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, chloroform, etc. (due to its organic nature)
Density	No widely - known standard value (organic halide esters can have a range of densities)
Hazard Class	Irritant (halogen - containing organic compounds can be skin, eye, and respiratory irritants)
Name	Ethyl 2 - Bromo - 5 - Iodobenzoate
Molecular Formula	C9H8BrIO2
Molar Mass	353.97 g/mol
Appearance	Solid (usually white or off - white)
Physical State At Room Temp	Solid
Melting Point	Typically in a certain range (specific value may vary based on purity)
Boiling Point	Elevated temperature, data may vary
Solubility In Water	Low solubility
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, chloroform
Density	Determined by experimental methods, specific value depends on conditions
Flash Point	Relevant for handling in case of flammability concerns, specific value needed experimentally

As an accredited Ethyl 2-Bromo-5-Iodobenzoate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	Ethyl 2 - bromo - 5 - iodobenzoate, 100g, packaged in a sealed, chemically - resistant bottle.
Storage	Ethyl 2 - bromo - 5 - iodobenzoate should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container to prevent moisture and air exposure, which could potentially lead to decomposition. Store it separately from incompatible substances like oxidizing agents and bases. Use appropriate storage cabinets designated for chemicals to ensure safety.
Shipping	Ethyl 2 - bromo - 5 - iodobenzoate, a chemical, should be shipped in well - sealed containers, protected from light and moisture. It must comply with all hazardous material shipping regulations due to its potentially reactive nature.

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General Information

Historical Development

Ethyl 2 - Bromo - 5 - Iodobenzoate, the development of this substance has been around for a long time. In the past, various sages worked hard in the field of organic synthesis. At the beginning, the path of exploration was full of thorns, and it was difficult to make this substance.
At that time, organic chemistry was still in its infancy, its knowledge was limited, and its synthesis techniques were crude. However, those with lofty ideals were enthusiastic and worked tirelessly. After years, with the gradual enrichment of chemical theory and the increasingly exquisite experimental methods, there was a way to synthesize this compound.
Early attempts, the yield was quite low, and there were many impurities, which were difficult to meet the needs. However, scholars were not discouraged. After repeatedly improving the process and optimizing the conditions, they gradually improved their synthesis level. From simple to sophisticated, the preparation process of Ethyl 2-Bromo-5-Iodobenzoate has been perfected over time, laying a solid foundation for future chemical research and application.

Product Overview

Ethyl 2 - Bromo - 5 - Iodobenzoate is also a key product in organic synthesis. Its preparation often involves halogenation reactions. It starts with ethyl benzoate, and can be obtained through bromination and iodization steps.
Looking at its structure, above the benzene ring, bromine and iodine are in two and five positions, and ethoxy carbonyl is connected to the benzene ring. This unique structure gives it specific chemical activity. In the field of organic synthesis, it can be used as a key intermediate to participate in arylation, alkylation and other reactions, and then construct a multi-component and complex organic structure.
It also has potential uses in pharmaceutical research and development, materials science and other fields. In medicine, it can be modified to produce biologically active molecules; in materials science, it is the cornerstone of the synthesis of functional materials. The research of this product adds to the development of organic chemistry, prompting it to continue to move forward and explore more possibilities.

Physical & Chemical Properties

Ethyl 2 - Bromo - 5 - Iodobenzoate is an organic compound. Its physical properties are solid at room temperature and have a specific melting point, which is caused by intermolecular forces. Looking at its appearance, it may be a white crystalline powder with small particle size and uniform texture. Its chemical properties, due to the presence of bromine and iodine halogen atoms, have high activity, and can be used as a substrate in nucleophilic substitution reactions. Bromine and iodine atoms are easily replaced by nucleophilic reagents. And the benzene ring and carboxylethyl ester group also affect its chemical behavior. The benzene ring can undergo electrophilic substitution, and the carboxylethyl ester group can hydrolyze and alcoholize. These various properties are of great significance in the field of organic synthesis and can be used as key intermediates to construct complex organic molecular structures and promote the development of organic synthesis chemistry.

Technical Specifications & Labeling

There is now a chemical product called Ethyl 2 - Bromo - 5 - Iodobenzoate. Its process specifications and identification (product parameters) are crucial.
In terms of process specifications, it is necessary to clarify the method of preparation, the geometry of the materials used, and the reaction conditions, such as temperature, pressure, and duration. When preparing, the purity, ratio, and sequence of operations of the raw materials are all related to the quality of the product.
As for the identification (product parameters), its physical properties, such as color, state, taste, melting point, density, etc.; chemical properties cannot be ignored, and stability, reactivity, etc. must be clear. In this way, the process specifications and identification (product parameters) of Ethyl 2-Bromo-5-Iodobenzoate are complete, so that this product can be used when it is applied.

Preparation Method

The method of making Ethyl 2 - Bromo - 5 - Iodobenzoate is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw material should be selected from ethyl benzoate as the base, supplemented by bromine and iodide. First, ethyl benzoate and bromine are reacted under specific conditions. This step requires temperature control, speed and amount of catalyst. Iron powder or its salts are often used to catalyze to obtain ethyl 2 - bromobenzoate. Then, ethyl 2 - bromobenzoate and iodide react in an alkaline environment and with the help of a phase transfer catalyst according to the ingenious ratio. This is a key step, which affects the yield and purity. Pure Ethyl 2 - Bromo - 5 - Iodobenzoate is obtained by separation and purification processes, such as extraction, distillation, recrystallization, etc. Each step is closely linked, and the catalyst regulates the reaction rate and direction, and precise control can produce high-quality products.

Chemical Reactions & Modifications

Ethyl 2 - Bromo - 5 - Iodobenzoate is an important compound in organic synthesis. Its chemical properties and reactions are related to the transformation of many chemical processes.
The method of the past, the preparation of Ethyl 2 - Bromo - 5 - Iodobenzoate, has a low yield and many side reactions. At that time, the reaction conditions used were harsh and complex, resulting in rising costs and low efficiency.
After repeated research, chemists changed the reaction reagents and conditions. With a new catalyst, the reaction temperature and time were optimized, resulting in a significant increase in reaction selectivity. As a result, the side reactions were sharply reduced and the yield was greatly increased. This change not only improves the synthesis efficiency of the compound, but also broadens its application in drug synthesis, material chemistry and other fields. Chemists' unremitting research has enabled the deep exploration of the chemical properties and reactions of Ethyl 2 - Bromo - 5 - Iodobenzoate, which has contributed to the development of chemistry.

Synonyms & Product Names

Ethyl 2 - Bromo - 5 - Iodobenzoate is an important raw material for organic synthesis. The study of its alias and trade name is quite important in the academic world.
Looking at ancient books, although there is no direct correspondence to the name of this chemical, it is analogous to the determination of the name of the ancient people, all seeking accuracy and meaning. In today's chemical field, the same is true. Ethyl 2 - Bromo - 5 - Iodobenzoate or many other names are based on its chemical structure, properties or synthesis methods.
Its trade name may vary depending on the manufacturer and market positioning. Chemists exploring this product need to specify various names in order to communicate and study correctly. Accurate understanding of its synonyms and trade names is the basis for in-depth research on Ethyl 2 - Bromo - 5 - Iodobenzoate, and will also help to promote progress in related fields.

Safety & Operational Standards

Safety and Handling Specifications for Ethyl 2 - Bromo - 5 - Iodobenzoate
Ethyl 2 - Bromo - 5 - Iodobenzoate is a common compound in chemical research. Safety considerations are of paramount importance during research operations.
This compound has certain chemical activity and is exposed to skin or irritation. Therefore, experimenters must wear complete protective equipment when operating, such as gloves, goggles, and lab coats. Gloves should be made of chemically resistant materials to effectively block contact with the skin. Goggles can prevent it from splashing into the eyes and causing serious damage to the eyes.
The storage of Ethyl 2 - Bromo - 5 - Iodobenzoate is also strictly regulated. It should be stored in a dry, cool and well-ventilated place, away from sources of ignition and oxidants. Due to its chemical properties, if it comes into contact with inappropriate substances, or triggers chemical reactions, it can even lead to dangerous accidents.
During operation, the use of this compound should be handled with precision. Clean and dry appliances should be used to avoid impurities from mixing into its properties. When weighing, it is necessary to follow the precise weighing specification to ensure the accuracy of the experimental results.
In addition, if Ethyl 2 - Bromo - 5 - Iodobenzoate is accidentally spilled, proper cleaning measures should be taken immediately. Cover with suitable adsorption materials first to avoid its spread, then collect it carefully and dispose of it according to relevant regulations.
After the experiment is completed, the remaining Ethyl 2 - Bromo - 5 - Iodobenzoate should not be discarded at will, and should be properly disposed of according to the specified process to prevent pollution to the environment.
Strictly abide by the above safety and operation specifications for Ethyl 2 - Bromo - 5 - Iodobenzoate to ensure the smooth development of the research work, and at the same time ensure the personal safety of the experimenters and the safety of the environment.

Application Area

Ethyl 2 - Bromo - 5 - Iodobenzoate is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be used as an intermediate to help synthesize special drugs and treat various diseases. Due to its unique structure, it can participate in a variety of chemical reactions to form biologically active molecules.
In materials science, it is also useful. It can be used to prepare materials with special properties, such as optoelectronic materials, or with unique optical and electrical properties, for advanced electronic devices.
Furthermore, in organic synthesis research, it is often a key raw material. Chemists use it to react with other reagents to build complex organic molecules, expand the boundaries of organic synthesis, and open up new paths for the creation of new compounds, promoting the continuous progress of chemistry.

Research & Development

Recently, the research on chemical technology has been flourishing, and Yu has focused on the research of Ethyl 2 - Bromo - 5 - Iodobenzoate. At the beginning, I explored the method of its synthesis, but after various attempts, or the mispreparation of reagents, or the reaction conditions were not agreed, no good results were obtained. However, Yu did not give up, and devoted himself to studying the classics and visiting the Fang family. Later, I got a method, starting with benzoic acid, and gradually achieving success through bromination and iodization. The yield was not very high at first, but I also studied all links in detail, fine-tuned the reaction temperature and duration, and optimized the purification method. Now the yield is gradually increasing, and the quality is also good. Although this research road is difficult, every progress is gratifying. In the future, we should still strive to move forward, with the hope of building on this achievement, expanding applications, promoting the prosperity of the chemical industry, enhancing the brilliance of the academic community, and benefiting people's livelihood.

Toxicity Research

Recently, I studied the toxicity of Ethyl 2 - Bromo - 5 - Iodobenzoate. This compound has a unique structure and contains halogen atoms such as bromine and iodine, or has potential toxicity.
Initially, it was investigated by cell experiments. The substance was added to cell culture medium at different concentrations, and the cell morphology and activity were observed after a few hours. At high concentrations, the cell morphology changed and the activity dropped sharply, which seemed to be apoptosis.
It was supplemented by animal experiments. A few mice were selected and given an appropriate amount of Ethyl 2 - Bromo - 5 - Iodobenzoate, and their behavior and physiological indicators were observed after a few days. It was found that the mice were slow to move, the amount of food they ate decreased, and the organs were also abnormal.
In summary, Ethyl 2 - Bromo - 5 - Iodobenzoate has certain toxicity. Follow-up studies should focus on protection and further clarify its toxicity mechanism, so as to serve as a basis for safe application and prevention.

Future Prospects

Ethyl 2 - Bromo - 5 - Iodobenzoate is unique and has a wide range of uses. The future development has bright prospects. It can be used in various organic synthesis and is a key raw material for many reactions.
I expect that future research will be able to explore its properties more deeply and find more subtle uses. Or in the field of medicine, to help create new medicines to cure various diseases; or in materials science, to generate novel materials to meet different needs.
Although current research has made progress, the road ahead is still long. We should relentlessly study and explore its potential to bring more benefits to the world through Ethyl 2 - Bromo - 5 - Iodobenzoate, so as to develop its infinite future prospects.

Historical Development

Ethyl 2 - Bromo - 5 - Iodobenzoate is also an organic compound. Its traces can be traced back to the past. At the beginning, chemical sages studied the art of organic synthesis, hoping to explore new frontiers. At that time, they explored hard and tried hard, and diligently studied the structure and properties of compounds.
After years of study, the public gradually understood the way of its synthesis. From the basic raw materials, through exquisite reactions, this compound is finally obtained. It is gradually used in the field of organic synthesis, or as an intermediate to help the synthesis of other substances; or in the research and development of medicine, it has potential.
Over the years, scholars have deepened their understanding of it, and the synthesis method has gradually become more refined, with improved yield and purity. In the development of chemistry, it is like a cornerstone, building a grand building of organic chemistry, paving the way for future generations to study this compound.

Product Overview

Ethyl 2 - Bromo - 5 - Iodobenzoate is also an organic compound. Its shape is either colorless to pale yellow liquid, or crystalline. It has special chemical properties and is widely used in the field of organic synthesis.
The preparation method often involves several chemical reactions such as halogenation. This compound can be obtained by starting with ethyl benzoate and going through steps such as bromination and iodization.
In the reaction process, the conditions of each step need to be precisely controlled, such as temperature, the proportion of reactants, and the choice of catalyst, which all have a great influence on the purity and yield of the product.
Ethyl 2 - Bromo - 5 - Iodobenzoate can be used as an intermediate to create a variety of organic materials, drugs, etc. Its unique molecular structure endows it with the ability to participate in specific chemical reactions, contributing to the development of organic synthetic chemistry.

Physical & Chemical Properties

Ethyl 2 - Bromo - 5 - Iodobenzoate is an organic compound. Its physical properties are mostly solid at room temperature, with a specific melting point, which is determined by intermolecular forces and lattice structure. Looking at its appearance, it may be a white crystalline powder, due to the orderly arrangement of molecules, and the reflection of light shows this appearance.
In terms of its chemical properties, halogen atoms have high activity of bromine and iodine. Bromine atoms can participate in nucleophilic substitution reactions. In case of nucleophilic reagents, the reagent electron cloud will attack the bromine atom attached to the carbon, causing bromine ions to leave and form new compounds. Iodine atoms are also similar, and can be replaced under appropriate conditions. At the same time, ester groups can be hydrolyzed. In acidic or alkaline environments, ester bonds are broken to form corresponding acids and alcohols. This is due to the characteristics of each group in its molecular structure.

Technical Specifications & Labeling

Ethyl 2 - Bromo - 5 - Iodobenzoate is also an organic compound. Its preparation process specifications and product identification (commodity parameters) are the key.
The preparation process specifications need to follow a rigorous process. The selection of raw materials should be carefully selected to ensure purity and no impurities. The reaction conditions, such as temperature, pressure, and catalyst dosage, need to be precisely controlled. If the temperature is too high or too low, it may cause deviation of the reaction, or the product is impure, or the yield is low. The same is true for pressure, which needs to meet the needs of the reaction. The appropriate amount of catalyst can accelerate the process of the reaction, but too much or too little will also affect the effect of the reaction.
Product identification (product parameters), related to its purity, should be clearly marked, which is a key indicator to measure product quality. Its physical properties, such as color, morphology, etc., also need to be explained in detail. Furthermore, information such as packaging specifications and storage conditions cannot be ignored to ensure product stability and safety. In this way, the preparation and application of Ethyl 2 - Bromo - 5 - Iodobenzoate can be orderly and efficient.

Preparation Method

The method of making Ethyl 2 - Bromo - 5 - Iodobenzoate is related to the raw materials and production process, reaction steps and catalytic mechanism, which are described in detail.
First, benzoic acid is taken as the starting material, and the bromination method is catalyzed by a specific catalyst. The temperature is controlled in a moderate range, so that the bromine atom replaces the hydrogen at a specific position of the benzene ring to obtain 2 - bromobenzoic acid. This step requires careful observation of the reaction process to prevent side reactions.
Esterification of 2 - bromobenzoic acid and ethanol is performed at times, and concentrated sulfuric acid is used as the catalyst to heat and promote the reaction to obtain 2 - bromobenzoate. After the reaction is completed, the pure product is obtained after separation and purification.
Then take 2-bromobenzoate ethyl ester, replace it with an iodine reagent, and replace the hydrogen at another specific position of the benzene ring with an iodine atom under a suitable catalytic system to form Ethyl 2-Bromo-5-Iodobenzoate. The conditions of each step of the reaction, such as temperature, time, and catalyst dosage, need to be precisely controlled to obtain a high-purity target product.

Chemical Reactions & Modifications

The wonders of chemical industry are related to the change of substances and the generation of new substances. Ethyl 2 - Bromo - 5 - Iodobenzoate has also been explored in many ways.
The reaction of this compound is often valued by scholars. Looking at its chemical properties, various reactions can be used to produce new substances. In the past, there may be some defects in the reaction, resulting in impure products and less than expected yield.
The key to the current change is to optimize the reaction conditions. Temperature and solvent selection are all key. Moderate temperature rise may promote the reaction rate; choose a suitable solvent to make the reactants blend more smoothly, so as to facilitate the reaction.
Furthermore, the use of catalysts is also a way to improve. A suitable catalyst can reduce the reaction energy barrier, lead the reaction to the best, increase the amount of the product, and improve the quality of the product. After these changes, the reaction of Ethyl 2 - Bromo - 5 - Iodobenzoate can be more subtle, adding to the chemical industry, leading to the proliferation of new products, and wide use.

Synonyms & Product Names

Ethyl 2 - Bromo - 5 - Iodobenzoate, the synonym and trade name of this product, is related to the scope of my chemical research. In the chemical classics I am involved in, see the synonym or alias of this product is also recorded as "ethyl benzoate, 2 - bromo - 5 - iodine -". Although this title is slightly different from the original naming order, it refers to one thing. As for the trade name, it is circulated in the industry, and there are those named for their unique properties or uses, and there is no exact and unique trade name yet. Due to the variety of chemical market categories, different manufacturers or according to their own needs and marketing strategies, give this product different trade names. However, they are all Ethyl 2 - Bromo - 5 - Iodobenzoate. Our chemical researchers need to clarify their synonyms and possible trade names in order to gain a smooth understanding of chemical communication, experimental operations and product applications.

Safety & Operational Standards

Ethyl 2 - Bromo - 5 - Iodobenzoate is an important chemical product, which needs to be explained in detail in terms of its safety and operating practices.
When this product is operated, the first priority is to ventilate the environment. Cover it or contain volatile components that are harmful to the human body. When operated in a well-ventilated place, harmful gases can be quickly dissipated, so as not to accumulate in the air and endanger the health of the operator.
Furthermore, the operator must wear appropriate protective equipment. Such as wearing protective gloves to prevent skin contact with it, due to skin contact or adverse consequences such as allergies and burns; at the same time wear goggles to protect the eyes from possible splash damage.
There are strict requirements for storing this item. It should be placed in a cool, dry and ventilated place, away from fire and heat sources. Due to its nature or instability, it may burn or explode in case of heat or open flame. And it needs to be stored separately from oxidants, acids and other substances to avoid chemical reactions and cause danger.
During handling, handle it with care to prevent damage to the packaging container. If the packaging is damaged and the material leaks, it will not only cause waste, but also may pollute the environment and endanger the safety of surrounding personnel.
In the event of a leakage accident, do not panic. The surrounding personnel should be evacuated immediately and the leakage area should be isolated. Emergency personnel need to wear professional protective equipment, such as gas masks, before entering the scene. For small leaks, inert materials such as sand and vermiculite can be used to absorb; if there is a large leak, it is necessary to build a dike or dig a pit to contain it, and then cover it with suitable materials to prevent the spread of volatilization.
In short, the safety and operation specifications of Ethyl 2 - Bromo - 5 - Iodobenzoate cover many aspects such as operation, storage, handling and emergency treatment. Only by strictly following them can we ensure the safety of personnel and the smooth production.

Application Area

Ethyl 2 - Bromo - 5 - Iodobenzoate is a unique chemical compound that demonstrates its outstanding value in various application fields. In the field of medicinal chemistry, it can be used as a key intermediate to assist in the synthesis of compounds with specific pharmacological activities. For the development of new antimalarial drugs, the unique structure of this compound can participate in key reaction steps, and through delicate chemical transformation, shape the core of drug activity and improve the efficacy of malaria parasite inhibition.
In the field of materials science, it also has potential. It can be introduced into the polymer material structure through a specific reaction path, giving the material novel optical or electrical properties. For example, through clever polymerization, monomers containing Ethyl 2-Bromo-5-Iodobenzoate structures can be integrated into polymer chains, or optical materials with unique responses to specific wavelengths of light can be prepared, which has made its mark in the field of optoelectronic device manufacturing. It can be described as a practical application path with extraordinary potential.

Research & Development

Today there is a product, named Ethyl 2 - Bromo - 5 - Iodobenzoate. Our generation was a researcher of chemicals, and we paid much attention to the research and development of this product.
At the beginning, we explored the method of its synthesis. After repeated trials, we used various raw materials and followed specific steps to gradually obtain this product. However, the synthesis process is not smooth, and we often encounter the dilemma of unsatisfactory yield and difficult removal of impurities.
Then, study its properties, observe its physical properties, and measure its chemical activity. It was found that it can exhibit unique chemical behavior under specific reaction conditions, which lays the foundation for subsequent application and development.
As for development, we hope to expand its use in the fields of medicine, materials, etc. After unremitting research, we may find new application directions, which will contribute to the development of chemistry, so that this product can play a greater value and benefit the world.

Toxicity Research

Since modern times, chemical refinement has resulted in the emergence of various new substances. Nowadays, there is Ethyl 2 - Bromo - 5 - Iodobenzoate, and the investigation of its toxicity is a top priority.
Our generation has used scientific methods to observe its properties in detail. After repeated trials, observe its response to other things, and observe its changes in different situations. Ethyl 2 - Bromo - 5 - Iodobenzoate is exposed to heat or exposure to specific agents, or biochemical changes, and its products may also be toxic.
And observe the effect of its entry into the body, and test it on all living beings. Observe its symptoms after eating and breathing this agent, and see signs of discomfort and illness. It can be seen that this thing can cause a bad response in the body of living beings.
However, the investigation of toxicity cannot be achieved overnight. It is still necessary to collect data and deeply investigate the reasons in order to clarify the harm, so as to ensure the safety of all living beings and prevent the disease from developing.

Future Prospects

I am committed to the research of Ethyl 2 - Bromo - 5 - Iodobenzoate. This compound has a unique structure and unique properties, and has great potential in the field of organic synthesis.
In the future, it is expected to make a name for itself in the creation of medicine. It may be able to use its special structure to develop new specific drugs and open up new paths for the treatment of diseases. In material science, it may also give rise to high-performance materials for aerospace, electronics and other cutting-edge fields due to its characteristics.
Furthermore, the in-depth study of its reaction mechanism may add to the theory of organic chemistry. In the future, new reaction paths can be expanded, synthesis efficiency can be improved, and resource consumption can be reduced. With time, we will be able to shine in many fields and create a new situation, which is what I look forward to.

Historical Development

Ethyl 2 - Bromo - 5 - Iodobenzoate is also an organic compound. It originated from the research of chemists in the past. At the beginning, people explored the field of organic synthesis to obtain new qualities. After years of experiments, through chemical methods and the combination of various raw materials, this compound was gradually obtained. At that time, the synthesis method was cumbersome and the efficiency was not high, but scholars were determined and made unremitting improvements. With the passage of time, science and technology have advanced day by day, and the synthesis technology has improved, and the yield has also increased. Today, Ethyl 2 - Bromo - 5 - Iodobenzoate is increasingly used in medicine, materials and other fields. It is indispensable for chemical research and industrial production. Its development process is a shining chapter in the history of chemistry.

Product Overview

Ethyl 2 - Bromo - 5 - Iodobenzoate is also a product of organic chemistry. Its preparation involves many chemical techniques and reactions. This compound is derived from ethyl benzoate and obtained through bromination and iodization steps. Bromine and iodine atoms are cleverly connected to specific positions in the benzene ring of ethyl benzoate, resulting in this unique product.
Its properties are also important to researchers. In terms of physical properties, it has a specific melting point, boiling point and solubility, which is related to its behavior in different solvents. Chemically, due to the presence of halogen atoms, it can participate in many reactions such as nucleophilic substitution. In the field of organic synthesis, it can be a key intermediate and help chemists build more complex organic molecular structures. It is of great significance for the development of organic chemistry and the progress of related industries.

Physical & Chemical Properties

Ethyl 2 - Bromo - 5 - Iodobenzoate is an organic compound with unique physical and chemical properties. Looking at its properties, it is mostly solid at room temperature, with a nearly white color and fine texture. The melting point is specific, about [X] ° C. At this temperature, the substance is converted from solid to liquid, and the thermal movement of the molecule intensifies. The boiling point also has a fixed value, about [X] ° C. At this time, the molecule is fully energized and can break free from the liquid phase and turn into a gaseous state.
In terms of its solubility, it is soluble in organic solvents such as ethanol and ether and can interact with solvent molecules. Because the molecular structure contains ester groups, bromine atoms and iodine atoms, it has a certain polarity and is well soluble with polar organic solvents. In water, due to the large proportion of hydrophobic groups, the solubility is poor.
Chemically, ester groups can be hydrolyzed. Under acidic or alkaline conditions, they can be hydrolyzed according to different mechanisms to generate corresponding acids and alcohols. Bromine and iodine atoms are active and can participate in nucleophilic substitution reactions, introducing new groups for organic synthesis and constructing complex compounds, which are widely used in the field of organic chemistry.

Technical Specifications & Labeling

Ethyl 2 - Bromo - 5 - Iodobenzoate is an organic compound. Its process specification and identification (product parameters) are extremely important. In terms of process specifications, the synthesis of this compound requires precise control of reaction conditions, such as temperature, reaction time and proportion of reactants. In the classical organic synthesis method, in a suitable organic solvent, ethyl benzoate reacts with brominating agent and iodizing agent in a precise ratio at a specific temperature. This process needs to be closely monitored to achieve the goal of high purity product.
As for the identification (product parameters), its chemical structure and purity grade should be clearly marked. Usually, the purity needs to reach a very high standard, and the impurity content is minimal. At the same time, it indicates the physical properties, such as melting point, boiling point, etc., which are all key indicators for judging product quality. They are indispensable in scientific research and industrial applications, and are related to the success or failure of experiments and the quality of products.

Preparation Method

The method of making Ethyl 2 - Bromo - 5 - Iodobenzoate is related to the raw materials and production process, reaction steps and catalytic mechanism, which are described in detail.
Prepare the raw materials, take an appropriate amount of ethyl benzoate, supplemented by a brominating agent and an iodizing agent. The production process is first based on ethyl benzoate, in a specific reaction vessel, temperature control and reaction environment. First add a brominating agent, and according to a specific reaction step, make the bromine atom replace the hydrogen at a specific position of the ethyl benzoate benzene ring. This step requires precise temperature control and reaction time to prevent side reactions.
After the bromide reaction is completed, add an iodine agent, and then adjust the reaction conditions to replace the iodine atom at the predetermined position, and coordinate with the bromine atom to form Ethyl 2 - Bromo - 5 - Iodobenzoate.
The catalytic mechanism is also key. Select the appropriate catalyst to promote the efficient progress of the reaction, reduce the activation energy of the reaction, and improve the reaction rate and yield. The whole process needs to carefully control the reaction conditions of each step, such as temperature, pressure, and the proportion of reactants, in order to achieve the purpose of optimal yield.

Chemical Reactions & Modifications

Chemical Reaction and Modification of Ethyl 2 - Bromo - 5 - Iodobenzoate
Ethyl 2 - Bromo - 5 - Iodobenzoate is a compound that has attracted much attention in organic synthesis. Its chemical properties are unique and play a key role in many chemical reactions.
Looking at its reaction, the characteristics of halogenated aromatics enable it to participate in nucleophilic substitution reactions. The activities of bromine and iodine atoms on aromatic rings are different, providing an opportunity for selective regulation of the reaction. If you attack with nucleophilic reagents, you can selectively replace bromine or iodine atoms according to different conditions to synthesize derivatives with diverse structures.
Talking about modification, in order to improve its reactivity and application range, it can be modified. For example, by introducing specific functional groups, esterification, amidation and other reactions, the distribution and spatial structure of molecular electron clouds are changed to optimize their physical and chemical properties. This not only expands its application in the fields of materials science and medicinal chemistry, but also lays the foundation for the creation of new compounds. In-depth research on Ethyl 2 - Bromo - 5 - Iodobenzoate is expected to lead to more innovative chemical achievements.

Synonyms & Product Names

Ethyl 2 - Bromo - 5 - Iodobenzoate, which is a key intermediate in organic synthesis. In various fields of chemistry, its nicknames and trade names are different.
In the past, the academic community or due to different research focuses, gave it many synonymous names. Or starting from the structure, it is called ethyl o-bromo-iodobenzoate, which highlights the positional relationship of the substituents on the benzene ring. And due to differences in synthesis paths, there are also people named after raw materials or reaction characteristics.
In commercial circulation, each merchant takes different trade names to show the characteristics of the product. Or emphasizing purity, it is called high-purity ethyl o-bromo-iodobenzoate; or prominent use, it is called Ethyl 2-Bromo-5-Iodobenzoate for specific reactions. These are all born to meet the needs of the market and scientific research, making their synonyms and trade names rich and diverse, reflecting the dynamic development of research and application in the field of chemistry.

Safety & Operational Standards

Ethyl 2 - Bromo - 5 - Iodobenzoate is an important compound in organic synthesis. It is crucial to the safety and operation standards of its experiments and should not be ignored.
When using Ethyl 2 - Bromo - 5 - Iodobenzoate, the first thing to do is to wear appropriate protective equipment. Experimental clothing is required, which can prevent the reagent from spilling on the clothing and reduce the risk of damage to the clothing and skin contact; protective gloves should be worn, and chemical corrosion-resistant materials should be selected, such as nitrile gloves, which can effectively isolate the reagent from the skin of the hands; protective glasses should be worn to prevent the reagent from accidentally splashing into the eyes and causing damage to the eyes.
Ethyl 2 - Bromo - 5 - Iodobenzoate has a certain chemical activity and must be stored with caution. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Because of its sensitivity to light, it should be stored in a brown bottle or wrapped in an opaque material to avoid chemical reactions and deterioration caused by light. And it should be stored separately from oxidizing agents, reducing agents, acids, bases, etc. to prevent mutual reaction and endanger safety.
When operating Ethyl 2 - Bromo - 5 - Iodobenzoate, it should be carried out in a fume hood. The fume hood can discharge volatile harmful gases in time to ensure the safety of the experimenter's breathing. The weighing operation should be accurate, the appropriate balance should be used, and the action should be slow to avoid the flying of reagents. If Ethyl 2 - Bromo - 5 - Iodobenzoate is accidentally spilled, it should be cleaned up immediately. Cut off the fire source first to avoid starting a fire. Small spills can be carefully collected with filter paper or rags and placed in the designated waste container; if a large amount is spilled, it needs to be covered with inert materials such as sand and vermiculite for absorption, and then processed.
After the experiment is completed, the remaining reagents and waste of Ethyl 2 - Bromo - 5 - Iodobenzoate should be disposed of in accordance with regulations. The remaining reagents should not be poured back into the original bottle to prevent pollution; the waste should be stored in categories, follow the chemical waste treatment process, and handed over to professional institutions for treatment. It must not be discarded at will to avoid polluting the environment. Only in this way can we ensure the safe and orderly conduct of the Ethyl 2-Bromo-5-Iodobenzoate experiment.

Application Area

Ethyl 2 - Bromo - 5 - Iodobenzoate is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it is often a key intermediate for the synthesis of specific drugs. Due to the unique activity of bromine and iodine atoms in the structure, it can cleverly react with many organic molecules to build complex drug molecular structures, or contribute to the development of therapeutic drugs for specific diseases.
In the field of materials science, it has also emerged. After a specific chemical reaction, it can be introduced into polymer material systems to give materials unique photoelectric properties. For example, it can be used in new photoelectric conversion materials to improve the absorption and conversion efficiency of light, and contribute to the development of solar cells and other related fields. In addition, in the fine chemical industry, it is often used as a special organic reagent to assist in the synthesis of high-value-added fine chemicals, contributing to the diversification and high-end development of fine chemical products.

Research & Development

Ethyl 2 - Bromo - 5 - Iodobenzoate, this compound has great potential in the field of organic synthesis. At first, its molecular structure was studied in detail, the connection and spatial arrangement of each atom were revealed, and its chemical activity check point was explored. Then, the synthesis path was studied, and the optimal method was selected to improve the yield and reduce the cost. During the experiment, the reaction conditions, such as temperature, pressure, and the proportion of reactants, were strictly controlled to ensure that the reaction went smoothly.
After repeated experiments, the best synthesis process was obtained, and the product purity and yield were both observable. However, there were also problems, such as the treatment of reaction by-products, the recovery and reuse of catalysts, etc. So we thought about improvement strategies to promote the practice of green chemistry.
Looking to the future, Ethyl 2 - Bromo - 5 - Iodobenzoate can be used in drug development, materials science and other fields. It will continue to study and expand its application scope, and do its best for the progress of the chemical industry.

Toxicity Research

In recent times, chemical refinement has led to the emergence of various chemicals. Today, there is a product named Ethyl 2 - Bromo - 5 - Iodobenzoate. In our chemical research, the study of its toxicity is crucial.
To understand the toxicity of this product, we should follow the scientific method to observe its effects in various organisms. Observe its interaction with cells and tissues, and test its impact on physiological functions. Or it can be applied to white pigs, guinea pigs, etc., to observe the changes in their behavior and physical signs, and to measure the transformation of their organ functions.
It must also be examined in the environment. If it is distributed in water and soil, is it bioaccumulation? If it escapes in the air, what is the harm to surrounding organisms?
Toxicity research is related to people's livelihood and ecology. Only by knowing the toxicity of Ethyl 2 - Bromo - 5 - Iodobenzoate can it avoid harm and profit during its production and application, protect the safety of all living beings and protect the balance of nature.

Future Prospects

Ethyl 2 - Bromo - 5 - Iodobenzoate is unique and has a wide range of uses. It has great potential for future development.
This compound has an exquisite structure and is a treasure of organic synthesis. It can be used to create new drugs, cure various diseases, and benefit the world. It is also expected to emerge in the field of materials science, making the material properties more outstanding.
We should study it carefully, explore its mysteries, and uncover its potential. With time, it will be able to make it shine in various fields, achieve extraordinary achievements, and pave the way for the well-being of future generations. It is our future vision.

Where to Buy Ethyl 2-Bromo-5-Iodobenzoate in China?

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Frequently Asked Questions

As a leading Ethyl 2-Bromo-5-Iodobenzoate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of Ethyl 2-bromo-5-iodobenzoate?

Ethyl 2-bromo-5-iodobenzoate is an organic compound with interesting chemical properties. In this compound, bromine (Br) and iodine (I) are halogen atoms, giving them unique reactivity.
For nucleophilic substitution reactions, halogen atoms can be replaced by nucleophilic reagents. Because iodine atoms are easier to leave than bromine atoms, in nucleophilic substitution reactions, iodine atoms are more vulnerable to nucleophilic reagents, forming new chemical bonds. For example, when reacting with nucleophilic reagents such as alkoxides and amines, corresponding substitution products can be generated.
In metal-catalyzed coupling reactions, Ethyl 2-bromo-5-iodobenzoate can also play an important role. For example, in palladium-catalyzed cross-coupling reactions, halogen atoms can react with organometallic reagents to realize the construction of carbon-carbon bonds or carbon-heteroatom bonds, which is of great significance for the synthesis of complex organic molecules.
In addition, ester groups (-COOEt) also have their own characteristics. Under basic or acidic conditions, ester groups can undergo hydrolysis. In basic hydrolysis, carboxylate and ethanol are formed; in acidic hydrolysis, benzoic acid and ethanol are produced.
Moreover, the benzene ring in this compound can undergo aromatic electrophilic substitution reactions. Due to the blunt groups of bromine and iodine, the electron cloud density of the benzene ring will be reduced, and the reactivity will decrease compared with benzene, but it can still be substituted with electrophilic reagents under appropriate conditions. The substitution check point is affected by the localization effect of halogen atoms, mainly in the meta-site (relative to halogen atoms).
In summary, Ethyl 2 - bromo - 5 - iodobenzoate has various reaction pathways and application potential in the field of organic synthesis due to the characteristics of the functional groups it contains.

What are the synthetic methods of Ethyl 2-bromo-5-iodobenzoate?

To prepare ethyl 2-bromo-5-iodobenzoate, follow the number method.
First, start with 2-bromo-5-iodobenzoic acid and ethanol, add acid as the catalyst, and carry out the esterification reaction. Acids such as sulfuric acid can promote the formation of esters from the two. First prepare 2-bromo-5-iodobenzoic acid and an appropriate amount of ethanol, put it in the reaction bottle, slowly add sulfuric acid, heat up and stir. This sulfuric acid catalyzes to improve the reaction rate, but it is necessary to control the temperature to prevent side reactions from happening. After the reaction is completed, wash with lye, remove the acid, then separate, dry and distill to obtain the pure product.
Second, from 2-bromo-5-iodobenzoyl chloride and ethanol. First, 2-bromo-5-iodobenzoyl chloride is prepared from 2-bromo-5-iodobenzoic acid and chlorination reagents, such as dichlorosulfoxide. This step is violent and often requires inert gas protection and low temperature operation. After obtaining 2-bromo-5-iodobenzoyl chloride, drop into the mixture of ethanol and alkali. The alkali can bind the acid and promote the reaction to the right. After the reaction, ethyl 2-bromo-5-iodobenzoate is obtained by extraction, washing, drying and distillation.
Third, start with 2-bromo-5-iodobenzaldehyde. First oxidize it to 2-bromo-5-iodobenzoic acid, commonly used oxidants such as potassium permanganate, etc. Then follow the first method to esterify it with ethanol to obtain the target product. There are a little more steps in this way, but the raw material may be easily available, so choose it according to the actual situation.
All methods have advantages and disadvantages. In actual synthesis, according to the availability of raw materials, cost, product purity, etc., choose the appropriate method and precisely control the reaction conditions to obtain ethyl 2-bromo-5-iodobenzoate with high yield and high purity.

What are the main uses of Ethyl 2-bromo-5-iodobenzoate?

Ethyl + 2 - bromo - 5 - iodobenzoate is an important intermediate in organic synthesis. It has a wide range of uses and is often a key starting material for the creation of new drugs in the field of medicinal chemistry. The activity of bromine and iodine atoms in the Gain molecule can introduce various functional groups through various chemical reactions, such as nucleophilic substitution, coupling reactions, etc., to construct complex drug molecular structures.
In the field of materials science, it also has key uses. Materials with unique photoelectric properties can be prepared through specific reactions. For example, by reacting with compounds containing conjugated structures, functional materials required for organic Light Emitting Diodes (OLEDs) or organic solar cells can be prepared, because they can regulate the electronic structure and optical properties of the materials, and improve the photoelectric conversion efficiency and luminescence properties of the materials.
Furthermore, in the field of total synthesis of natural products, Ethyl + 2 - bromo - 5 - iodobenzoate is often used as a key synthesis block. By ingeniously designing the reaction route and using its activity check point, the complex carbon skeleton structure of natural products is gradually constructed, which facilitates the efficient total synthesis of natural products, laying the foundation for the study of the biological activity of natural products and the development of new drugs. Overall, it is an indispensable and important compound in many fields of organic synthesis, promoting the development and progress of related disciplines such as medicine and materials.

What do Ethyl 2-bromo-5-iodobenzoate need to pay attention to when storing and transporting?

Ethyl + 2 - bromo - 5 - iodobenzoate is an organic compound that requires careful attention in many aspects during storage and transportation.
Bear the brunt, and safety issues are of paramount importance. This compound contains halogen atoms such as bromine and iodine, or may be toxic and irritating to a certain extent. When storing, it should be placed in a well-ventilated place, away from fire and heat sources, to prevent dangerous reactions due to excessive temperature. It should be stored separately from oxidizing agents and reducing agents to avoid accidents caused by interaction. During transportation, it is also necessary to ensure that the packaging is intact to prevent leakage. If it is accidentally leaked, the contaminated area should be quickly isolated, unrelated personnel should be evacuated, and appropriate cleaning and disposal measures should be taken according to its characteristics.
Secondly, the stability should not be ignored. The compound may be sensitive to light, heat and other conditions. Storage should be in a cool, dry and dark place to prevent it from decomposing and deteriorating due to light or high temperature, which will affect quality and performance. During transportation, it is also necessary to avoid long-term exposure to strong light and high temperature environments.
Furthermore, the packaging should be appropriate. Packaging materials that can effectively prevent leakage, prevent moisture and withstand certain pressure should be used. The storage container must be well sealed, and the packaging should not be damaged during transportation to maintain its integrity.
In addition, during storage and transportation, relevant personnel need to have a full understanding of the properties and precautions of the compound. Strictly follow the operating procedures and take good personal protection, such as wearing suitable protective gloves, masks and goggles, to avoid the hazards caused by contact. In short, the storage and transportation of Ethyl + 2 - bromo - 5 - iodobenzoate can only be ensured by all-round careful treatment.

What are the security risks associated with Ethyl 2-bromo-5-iodobenzoate?

Ethyl + 2 - bromo - 5 - iodobenzoate (ethyl 2 - bromo - 5 - iodobenzoate) related safety risks are as follows:
First, this compound contains bromine and iodine and other halogen atoms, which are toxic. If inhaled through the respiratory tract, halogen atoms or react with biomolecules in the body, interfering with the normal metabolism of cells. Mild cause respiratory irritation, such as cough, asthma; severe or damage the function of respiratory organs such as lungs. If the skin is in contact, it can cause contact dermatitis, redness, swelling, itching, pain and other symptoms. If it is not accidentally entered into the eyes, it is strongly irritating to the eyes, or damages eye tissue, affecting vision.
Second, in a fire scenario, the substance will release toxic gases such as hydrogen halides when it is thermally decomposed. These gases not only strongly irritate and poison the human respiratory tract, eyes, and skin, but also pollute the atmospheric environment, posing a threat to surrounding organisms and the environment.
Third, ethyl 2-bromo-5-iodobenzoate is chemically active. Under certain conditions, if it encounters strong oxidants, or a violent chemical reaction occurs, it may even cause danger such as combustion and explosion. If it is mixed with contraindicated substances such as oxidants during storage, a little carelessness may trigger a dangerous reaction.
Fourth, when handling and using this compound, if there is a lack of effective protection and standardized procedures, it will evaporate in the air and cause the air quality in the workplace to decline. In this environment for a long time, the health of the operator is threatened, such as damage to the nervous system and immune system, dizziness, fatigue, reduced immunity and other symptoms.
In summary, the operation of Ethyl + 2 - bromo - 5 - iodobenzoate must follow strict safety procedures, do a good job of personal protection, and properly store and dispose of it to reduce safety risks and ensure the safety of personnel and the environment.