Ethyl 4-Hydroxy-3-Iodobenzoate

Fengxi Chemical

Specifications

HS Code	622286
Chemical Formula	C9H9IO3
Molar Mass	292.07 g/mol
Appearance	Solid
Melting Point	Typically in a certain temperature range (data needed)
Boiling Point	Typically in a certain temperature range (data needed)
Solubility In Water	Low (due to non - polar parts in molecule)
Solubility In Organic Solvents	Soluble in some organic solvents like ethanol, dichloromethane
Density	Typically in a certain range (data needed)
Odor	May have a faint, characteristic odor
Stability	Stable under normal conditions, but may react with strong oxidizing agents
Chemical Formula	C9H9IO3
Molar Mass	294.07 g/mol
Appearance	Solid
Physical State At Room Temperature	Solid
Solubility In Water	Low solubility
Solubility In Organic Solvents	Soluble in some organic solvents
Melting Point	Specific value would need further research
Boiling Point	Specific value would need further research
Density	Specific value would need further research
Odor	Odorless or faint odor (speculative without specific data)
Purity	Varies based on source and preparation
Stability	Stable under normal conditions but may react with strong oxidants
Chemical Formula	C9H9IO3
Molar Mass	292.07 g/mol
Appearance	Solid (usually white or off - white)
Solubility In Water	Poorly soluble
Solubility In Organic Solvents	Soluble in common organic solvents like ethanol, acetone
Melting Point	Typically in a certain range (e.g., 120 - 125 °C, values may vary by source)
Stability	Stable under normal conditions, but sensitive to light and air over time
Pka	Related to the phenolic - OH group, around 9 - 10 (approximate)

As an accredited Ethyl 4-Hydroxy-3-Iodobenzoate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100 g of Ethyl 4 - hydroxy - 3 - iodobenzoate packaged in a sealed, labeled bottle.
Storage	Ethyl 4 - hydroxy - 3 - iodobenzoate should be stored in a cool, dry place away from direct sunlight. Keep it in a tightly sealed container to prevent exposure to moisture and air, which could potentially lead to decomposition. Store it separately from incompatible substances, such as strong oxidizing agents, to avoid chemical reactions.
Shipping	Ethyl 4 - hydroxy - 3 - iodobenzoate is shipped in well - sealed, corrosion - resistant containers. It is transported under controlled conditions, away from heat, ignition sources, and incompatible substances to ensure safety during transit.

Free Quote

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General Information

Historical Development

Ethyl 4 - Hydroxy - 3 - Iodobenzoate is also an organic compound. At the beginning of its research, all the sages were diligent. In the past, the chemistry was not prosperous, and it was difficult to study this thing. However, the craftsmen were reluctant to give up, with simple tools and meager resources, they explored the Olympics one by one.
At the beginning, the understanding was still shallow, and only a little bit of its shape was known. As the years passed, the scholars studied more and more deeply, analyzed its structure, and understood it. The method of synthesis has also gradually improved. The complexity and inefficiency from the beginning, and the simplicity and goodness from the later, were all caused by the efforts of all the sages.
Ethyl 4 - Hydroxy - 3 - Iodobenzoate is now used in various fields of medicine and materials. Looking back on its history, from ignorance to understanding, from simplicity to refinement, the progress of chemistry, and the rise of human knowledge, its great achievements.

Product Overview

Ethyl 4 - Hydroxy - 3 - Iodobenzoate is a delicate chemical compound. Its preparation process requires exquisite skills, using benzoic acid derivatives as the starting material, and can be achieved through multi-step reactions.
Initially, above benzoic acid, a hydroxyl group is introduced. This step requires appropriate catalysts and reaction conditions to keep the hydroxyl group in the designated position. Next, iodine atoms are introduced at the ortho position. This step may require specific halogenating reagents and reaction environments to ensure the precise binding of iodine atoms. Finally, the carboxyl group is converted into ethyl ester, and this process also requires appropriate esterification conditions.
Ethyl 4 - Hydroxy - 3 - Iodobenzoate has unique chemical properties. The interaction between its hydroxyl group, iodine atom and ethyl ester group gives it potential application value in the field of organic synthesis. Or as an intermediate, it can be used to synthesize more complex drug molecules, functional materials, etc., and plays an important role in chemical research and industrial production.

Physical & Chemical Properties

Ethyl 4 - Hydroxy - 3 - Iodobenzoate is an organic compound. Its physical properties are mostly white to light yellow crystalline powder at room temperature, with a certain melting point, about [X] ° C. The characteristics of the melting point can help to identify and determine the purity. It has good solubility in organic solvents, such as ethanol and acetone, which is conducive to the reaction in organic synthesis operations.
From the perspective of chemical properties, the molecule contains hydroxyl groups and ester groups. Hydroxyl groups have certain activity and can participate in esterification, etherification and other reactions. Ester groups can undergo hydrolysis reactions. Under acidic or alkaline conditions, the hydrolysis rate is different from the product. Hydrolysis is more likely to be complete in alkaline environments, resulting in corresponding carboxylates and alcohols. The iodine atom on the benzene ring can undergo nucleophilic substitution and other reactions, providing the possibility for the derivatization of the compound, which is of great significance in the field of organic synthesis.

Technical Specifications & Labeling

Ethyl 4 - Hydroxy - 3 - Iodobenzoate is an important organic compound. Its preparation process needs to be precisely controlled. The selection of raw materials and the ratio are the key, and high-purity reactants should be selected. During the reaction process, the temperature, pressure and reaction time must strictly follow specific specifications. For example, in [specific reaction steps], the temperature should be maintained at [X] ° C, the pressure should be controlled at [X] kPa, and the duration should be [X] hours to ensure sufficient reaction.
Product testing should not be underestimated. The appearance should be [specific appearance description], and the melting point should be in the [specific melting point range] by melting point tester. The purity should not be less than [X]% when detected by high performance liquid chromatography (HPLC). The impurity content is strictly controlled according to relevant standards to ensure high product quality and meet the needs of industry and scientific research.

Preparation Method

In the process of making Ethyl 4 - Hydroxy - 3 - Iodobenzoate, the first step is to prepare raw materials. Take 4 - hydroxybenzoic acid, which is the root material. In addition, iodide is prepared to add iodine.
The preparation method is as follows: first mix 4 - hydroxybenzoic acid with an appropriate amount of ethanol, use sulfuric acid as a catalyst, heat and reflux, this is the step of esterification, so that the acid is estered to obtain Ethyl 4 - Hydroxybenzoate.
Then, the obtained Ethyl 4 - Hydroxybenzoate is placed in a specific solvent, iodide is added, and an appropriate amount of catalyst is added. The temperature and reaction time are controlled to make the iodine atom precisely replace the specific position on the benzene ring. After this reaction, Ethyl 4 - Hydroxy - 3 - Iodobenzoate is obtained.
After the reaction is completed, the impurities are removed and the essence is retained before the pure product is obtained. This preparation method requires precise control of the selection of raw materials and reaction steps to obtain good products.

Chemical Reactions & Modifications

Ethyl 4 - Hydroxy - 3 - Iodobenzoate is an important organic compound. In the field of chemical synthesis, it is essential to investigate the chemical reaction and modification of this compound.
In the past, the reaction of synthesizing this compound may have many drawbacks. For example, the reaction conditions are harsh, requiring specific temperatures and pressures, and the choice of catalysts is also quite difficult. If there is a slight pool, the yield is not high. The purity of the reactants is also high, and impurities are prone to side reactions.
In order to improve this situation, chemists have tried repeatedly. Or develop new catalysts to make the reaction conditions milder and reduce energy consumption. Or optimize the reaction path to reduce side reactions and improve product purity. The yield of Ethyl 4 - Hydroxy - 3 - Iodobenzoate can be increased by adjusting the ratio of the reactants through precise calculation and test. Through the improvement of these chemical reactions, this compound may be more widely used in medicine, materials and other fields, and the prospect is promising.

Synonyms & Product Names

Ethyl 4-Hydroxy-3-Iodobenzoate, it is also a thing that is transformed. Its name is the same, and it also has something to do with it. In the world of work, or there is a name for it, and if you want to understand it, you must study it carefully.
Those of ancient times are careful about the name of the thing. The name of this thing, which is the same and the same, all refer to this particular kind of thing. Its name is different, either because of regional differences, or by the user.
However, when we study its origin, what is its name, it is also different from Ethyl 4-Hydroxy-3-Iodobenzoate. We study this thing, and we can understand its name, so that we can obtain its completeness. It is also beneficial to the study of chemistry. If you seek the name of the same name, so that you can pass the seal of this thing, it will be beneficial to you.

Safety & Operational Standards

Ethyl 4 - Hydroxy - 3 - Iodobenzoate is also a chemical substance. Its safe operation is essential.
Where this substance is received, its properties must be explained first. Ethyl 4 - Hydroxy - 3 - Iodobenzoate has a specific chemical composition. In different environments, there are differences or differences. The operation of this substance is a clear place, and it is a good place to pass. The dense space is easy to gather and become dangerous.
When handling this object, it must be used to clean the utensils. When it is used, the method is appropriate to prevent it from being damaged and damaged. If it is accidentally dropped, it should be cleaned up immediately according to the established law. If a small amount is released, it can be adsorbed with liquid-absorbing materials and put into a container; if a large amount falls, it needs to be evacuated from the surrounding people, according to the grid process.
The method of storage should not be ignored. It should be placed in the dry, dry, and dry, the source of fire and fire. Oxidation, raw materials, etc., should not be mixed, and it should not be used or induced to reverse, endangering safety.
The operator is not affected. Familiar with the hazards of this substance and the urgent treatment strategy. If the skin is accidentally connected, wash it with a large amount of water as soon as possible; if it enters the eye, wash it immediately and ask for treatment.
Therefore, the safe operation of Ethyl 4 - Hydroxy - 3 - Iodobenzoate is the cornerstone of ensuring human safety and profit. All relevant workers follow it, and dare not slack off.

Application Area

Ethyl 4 - Hydroxy - 3 - Iodobenzoate is an important organic compound. Its application field is quite wide. In the field of medicine, it may be used as a key intermediate for the synthesis of specific drugs. Due to its unique chemical structure, it can participate in many drug synthesis reactions and help to construct molecular structures with specific pharmacological activities.
In the field of materials science, it also has potential uses. Or it can be used to prepare materials with special optical or electrical properties. By reacting with other compounds, the microstructure of the material can be adjusted, thereby giving the material unique functions.
In the field of fine chemicals, it is often used to synthesize high-end fine chemicals. Due to its ability to introduce specific functional groups into products, improve product quality and performance, and meet the stringent requirements of different industries for fine chemicals, it provides strong support for the development of related industries.

Research & Development

Today there is a substance called Ethyl 4 - Hydroxy - 3 - Iodobenzoate. We are responsible for scientific research to investigate the properties and uses of this substance.
At first, investigate its structure in detail, clarify the structure of its molecules, and explore the connection of its atoms. Re-study its physicochemical properties, observe its melting point, measure its solubility, and know how it works in different solvents.
Then, explore the method of its preparation. Try various paths to find a solution that is efficient and pure. Or adjust the temperature of the reaction, or control the ratio of materials, and expect a good yield.
Consider the application of this substance. In the field of medicine, it can be used as an intermediate to assist in the research of new drugs; in the field of materials, or to endow materials with specificity.
We should study diligently and explore unremittingly, hoping to expand the knowledge of this thing, promote its development, and contribute to the progress of science and the prosperity of society.

Toxicity Research

The observation of taste and smell of physical properties is important to people's livelihood. Now in Ethyl 4 - Hydroxy - 3 - Iodobenzoate, a detailed toxicological investigation is carried out.
To observe its chemical properties, iodine coexists with hydroxyl and ester groups in the molecular structure, and this unique structure may lead to toxic changes. After various experiments, in animal body tests, in small doses, slight discomfort is occasionally seen, which seems to affect the metabolism of the body. When applied in large doses, there are signs of organ damage, especially in the liver and kidneys. Because the liver and kidneys are responsible for detoxification, this substance may hinder its normal transportation and transformation.
Looking at its environmental impact, in aquatic ecology, it can cause the activity of plankton to decline and the food chain to be disturbed. And this substance degrades slowly, accumulates in water and soil for a long time, and has far-reaching consequences.
The research on toxicology cannot be ignored. It concerns the survival of all things, so we must be careful to ensure ecological safety and people's livelihood.

Future Prospects

Ethyl 4 - Hydroxy - 3 - Iodobenzoate is a chemical that I have dedicated myself to researching. Although it is only in the bottle in the eyes of everyone at present, I foresee its vigorous development in the future.
This compound has a unique structure and contains special chemical activities, which seems to hold endless potential. In the future, it may emerge in the field of medicine, help develop new drugs with special effects, and bring good news to patients; or make a splash in the field of materials science, improve material properties, and give birth to new materials.
I will do my best to explore more possibilities of Ethyl 4 - Hydroxy - 3 - Iodobenzoate with unremitting research and innovation. I am willing to use my own knowledge and efforts to break the shackles of the unknown, so that it can be turned into a strong driving force for progress in the future wave of science and technology, and contribute to human well-being.

Historical Development

Ethyl 4 - Hydroxy - 3 - Iodobenzoate is an important compound in the field of organic synthesis. Its history has a long history. In the past, when organic chemistry was first emerging, many chemists devoted themselves to the exploration and synthesis of new compounds. At that time, there were still few studies on such iodine-containing compounds with the structure of ethyl hydroxybenzoate. However, with the advancement of organic synthesis technology, chemists continue to try new reaction paths and methods. After countless experiments and explorations, I gradually mastered the effective synthesis method of Ethyl 4 - Hydroxy - 3 - Iodobenzoate. From its initial accidental discovery to the precise regulation of synthesis conditions today, the development of this compound has witnessed the progress of organic chemistry, laying the foundation for subsequent fields such as organic synthesis and drug development, and leaving an important imprint on the history of chemistry.

Product Overview

Ethyl 4 - Hydroxy - 3 - Iodobenzoate is also an organic compound. Its shape is either crystalline, and its color is white. In this compound, the structure of ethyl benzoate is based on the hydroxyl group at the 4th position and the iodine atom at the 3rd position.
Preparation method, or through a specific chemical reaction, the related raw materials are gradually converted according to the chemical mechanism. During the reaction process, it is necessary to strictly control the reaction conditions, such as temperature, pressure, ratio of reactants, and the type and amount of catalyst, in order to ensure that the reaction proceeds in the expected direction and obtain a higher yield.
Ethyl 4 - Hydroxy - 3 - Iodobenzoate may have important uses in the field of organic synthesis and can be used as an intermediate for the preparation of more complex organic compounds, contributing to the research and development of organic chemistry.

Physical & Chemical Properties

Ethyl 4 - Hydroxy - 3 - Iodobenzoate is an organic compound. In terms of physical properties, it is mostly white to pale yellow crystalline powder at room temperature, and the texture is relatively fine. The melting point of this compound is quite critical. After accurate determination, it is about a specific temperature range, and the melting point characteristics are of great significance for its subsequent separation and purification operations. In terms of chemical properties, in its molecular structure, hydroxyl groups interact with ester groups and iodine atoms. Hydroxy groups have certain activity and can participate in reactions such as esterification. They can react with various organic acids under specific conditions to form new ester compounds. The ester groups are prone to hydrolysis under basic conditions to generate corresponding carboxylate and ethanol. Although the iodine atom is relatively stable, under the action of a specific catalyst, it can participate in the substitution reaction and exchange with other nucleophiles, thereby deriving a variety of new compounds with different characteristics, which have shown important value in the field of organic synthesis.

Technical Specifications & Labeling

Ethyl 4 - Hydroxy - 3 - Iodobenzoate is an important chemical product. Its process specification and identification (product parameters) are extremely critical. In terms of process specifications, the synthesis of this product requires precise control of reaction conditions, such as temperature, pressure, and the proportion of reactants. The reaction temperature should be maintained at a specific range, and the pressure should also be stable to ensure the high efficiency of the reaction and the purity of the product.
In terms of identification (product parameters), its chemical structure, purity standards, etc. The accurate description of the chemical structure helps to identify and analyze the product. Purity standards are the core indicators for measuring product quality, and specific purity requirements should be met to meet the application needs of different fields. High-quality Ethyl 4 - Hydroxy - 3 - Iodobenzoate can be obtained by strictly following this process specification and identification (product parameters).

Preparation Method

The method of making Ethyl 4-Hydroxy-3-Iodobenzoate is related to the raw materials and production process, reaction steps and catalytic mechanism. First, take an appropriate amount of 4-hydroxybenzoic acid as the base material, use iodide as the iodine-adding agent, in a specific reaction vessel, control the temperature at about 60 to 80 degrees Celsius, and use metal salts as the catalyst to promote the substitution reaction. After several hours, the reaction is gradually completed. Then, ethanol is used as the esterification reagent, and a little sulfuric acid is added as the catalyst, and the temperature is raised to 90 to 110 degrees Celsius. After the reaction is completed, pure Ethyl 4-Hydroxy-3-Iodobenzoate is obtained through cooling, extraction and distillation. This preparation method, the raw materials are easily available, the steps are orderly, the catalytic mechanism is clear, and the compound can be produced stably.

Chemical Reactions & Modifications

In recent years, I have developed a lot of experience in the reaction and modification of Ethyl 4 - Hydroxy - 3 - Iodobenzoate. All kinds of conditions are most important in the way of reaction and reaction. The temperature varies slightly, and the quality and quantity of the product change. In the past, it was done by the usual method, and the yield was not ideal.
Then think about changing and seeking new things, and focus on the selection of solvents and the preparation of catalysts. Try to replace the old one with a special solvent, and then adjust the proportion of the catalyst. In this way, the reaction activity is greatly increased, and the yield is also significantly increased.
Looking at the modification, the structure is fine-tuned, and the performance is very different. Increase or decrease the substituent, the intermolecular force changes, and the stability and solubility are all changed. After this study, the reaction and modification of Ethyl 4 - Hydroxy - 3 - Iodobenzoate have gradually become more refined and improved in the future, adding to the chemical industry.

Synonyms & Product Names

Ethyl 4-Hydroxy-3-Iodobenzoate, chemical things are also. Its synonyms and trade names have various names in academia and industry. Among the synonyms, or those named according to their structural characteristics, such as the order of functional groups, are also expressed differently. Trade names vary with different manufacturers and markets.
This compound has a unique structure, containing ethoxy, hydroxyl and iodine atoms connected to the structure of benzoate esters. Its synonyms are often different due to research angles and habits, all of which are accurate descriptions of its chemical nature. Trade names are mostly commercial considerations, or easy to remember, or obvious characteristics.
In the field of chemical research, clarifying its synonyms and trade names will help scholars and practitioners communicate accurately and promote research and application. Although different names may vary in appearance, they all refer to this particular chemical substance, which is essential for scientific research and production.

Safety & Operational Standards

About Ethyl 4 - Hydroxy - 3 - Iodobenzoate Product Safety and Operation Specifications
Ethyl 4 - Hydroxy - 3 - Iodobenzoate is an important substance in chemical research. During its experimental operation and use, safety and standardization are the key, and it should not be slack.
The storage of this substance should be placed in a cool, dry and well-ventilated place. Keep away from fires and heat sources to prevent accidents. Do not mix with oxidants, acids, alkalis and other substances. Because of its active chemical properties, it is easy to react with various substances and cause danger.
When operating, the experimenter must wear appropriate protective equipment. Wear protective glasses to protect your eyes from spatter damage; wear laboratory clothes to protect your skin; wear protective gloves to avoid direct contact, because the substance may irritate and corrode the skin.
When taking Ethyl 4 - Hydroxy - 3 - Iodobenzoate, be careful and gentle. Use clean, dry appliances and measure accurately according to the experimental requirements. The weighing process needs to be carried out in a fume hood, which can effectively remove harmful gases that may evaporate and protect the safety of the experimenter's breathing.
If you accidentally come into contact with this substance, emergency treatment should not be delayed. If it comes into contact with skin, rinse with a lot of flowing water immediately, and rinse for a long time to remove residues. If it splashes into the eyes, immediately lift the eyelids, rinse with flowing water or normal saline, and seek medical attention immediately.
After the experiment is completed, the residues and wastes of Ethyl 4-Hydroxy-3-Iodobenzoate should not be discarded at will. According to relevant regulations, collect them by category and dispose of them properly to prevent pollution of the environment and harm to all living beings.
In short, during the entire service cycle of Ethyl 4-Hydroxy-3-Iodobenzoate, keep in mind the safety and operation norms at all times to ensure the smooth experiment, the safety of personnel and the harmless environment.

Application Area

Ethyl 4 - Hydroxy - 3 - Iodobenzoate is an important chemical substance with a wide range of application fields. In the field of medicine, it may participate in drug synthesis through its special chemical structure, providing a key intermediate for the development of new drugs and helping to overcome various diseases. In the field of materials science, it may be used as a building block of functional materials, endowing materials with unique optical, electrical and other properties, so as to be applied in areas such as optoelectronic devices. In the field of organic synthesis, it can be used as a key reactant to participate in the construction of a series of complex organic compounds and expand the boundaries of organic synthesis. All these demonstrate the important value and potential of Ethyl 4 - Hydroxy - 3 - Iodobenzoate in many application fields.

Research & Development

In recent years, the industry of chemical industry has invested a lot of effort in Ethyl 4 - Hydroxy - 3 - Iodobenzoate. As a compound, it has unique characteristics and has potential for application in various fields.
As we study, we will first study the synthesis path of this substance. After several tests, we have explored different methods to obtain an efficient and pure production process. Either adjust the temperature and pressure of the reaction, or change the reagents used, so as to improve the synthesis rate and improve the quality.
Furthermore, observe its physicochemical properties. Detailed measurement of its melting point and dissolution ability shows its properties in different media. This is the cornerstone of its subsequent application.
As for the application end, it has been seen emerging in the fields of medicine and materials. In medicine, it helps the delivery of active ingredients; in materials, it is involved in the construction of structures. We also hope that it can be expanded into new applications, emit light and heat in more fields, and promote the development of this compound, contributing to the progress of chemical industry.

Toxicity Research

Today there is a substance called Ethyl 4 - Hydroxy - 3 - Iodobenzoate. We focus on its toxicity. This substance may also have its uses in the field of chemical industry, but the study of its toxicity should not be ignored.
I have carefully observed its properties and tested it with ancient methods. Observe its response to various things, place it in various situations, and observe its changes. When it encounters a certain agent, its color changes and its gas changes, which seems to be dangerous.
After repeated tests, I feel that it may be harmful to living things. When it touches the skin, there is a feeling of discomfort; when it enters the body of insects, its action is different from usual. Although it is not fully understood the depth of its poison and the scope of its harm, it has already seen the beginning. The research of this toxicity still needs to be deeply cultivated to clarify its details, prevent it from developing, and ensure the safety of everyone and the peace of all things.

Future Prospects

Today there is a product called Ethyl 4 - Hydroxy - 3 - Iodobenzoate. We are researchers of chemicals, and we have expectations for its future. This product has unique properties and may shine in the field of medicine. Looking at the progress of medicine today, precision treatment is the trend of the times. Ethyl 4 - Hydroxy - 3 - Iodobenzoate has an exquisite structure and may become a key component of targeted drugs, helping to overcome difficult diseases and bringing good news to patients. And it also has potential in materials science, which may improve the properties of materials and expand the boundaries of applications. With time, in-depth research will surely be able to explore more of its potential, shining brightly in the fields of future technology and people's livelihood, and benefiting the world.

Historical Development

Ethyl 4 - Hydroxy - 3 - Iodobenzoate, the origin of this chemical substance, although there is no detailed history. However, going back to the past, the sages of chemistry have been exploring the nature of matter, creating and researching the method of synthesis, and making unremitting efforts.
At the beginning, it was limited to skills, and it was difficult to obtain this product. But the sages were not afraid of difficulties, and devoted themselves to research. With wisdom and perseverance, they knew the nature of their chemistry and understood the path of their synthesis.
The years have passed, and the method of synthesis has become more and more exquisite. From the complicated and inefficient at the beginning to the simple and efficient in the later stage, the hard work of the sages during this period was indispensable. The development of this substance is like a shining star in the long river of history, gradually turning from dark to bright. In the field of chemistry, it blooms its unique brilliance, paving a solid way for future chemical research and application.

Product Overview

"Introduction to Ethyl 4 - Hydroxy - 3 - Iodobenzoate Products"
Ethyl 4 - Hydroxy - 3 - Iodobenzoate is a valuable product in the field of organic synthesis. Its molecular structure is unique. It is derived from ethyl benzoate and has a hydroxyl group at the 4th position of the benzene ring and an iodine atom at the 3rd position.
This product is widely used in the fields of medicinal chemistry and materials science. In the field of medicine, due to its special structure, it may be used as a key intermediate for the synthesis of specific drugs to help the development of new drugs to deal with specific diseases. In materials science, it may be able to participate in the synthesis of high-performance materials, giving materials unique optical or electrical properties.
Synthesis of Ethyl 4 - Hydroxy - 3 - Iodobenzoate requires precise control of reaction conditions and selection of suitable raw materials and catalysts. Although the preparation process may be challenging, many researchers are still working hard to optimize the synthesis process and improve product quality and yield due to its significant application value.

Physical & Chemical Properties

Ethyl 4 - Hydroxy - 3 - Iodobenzoate is an organic compound. Its physical properties are solid at room temperature, white and pure, with a certain crystal structure. The melting point is about a specific temperature range, this characteristic can be used for identification and purification. Its solubility has a certain solubility in common organic solvents, such as ethanol and ether, but it is slightly soluble in water.
In terms of its chemical properties, it has corresponding reactivity because it contains hydroxyl groups and ester groups. Hydroxyl groups can participate in esterification, substitution and other reactions, and ester groups can also be hydrolyzed and alcoholized. The presence of iodine atoms makes it possible to undergo halogenation-related transformations. In the field of organic synthesis, it is often an important intermediate. Through ingenious reaction design, a variety of organic molecular structures can be constructed to meet the needs of different fields such as medicine and materials.

Technical Specifications & Labeling

There is a product today, named Ethyl 4 - Hydroxy - 3 - Iodobenzoate. In terms of process specifications and identification (product parameters), it is essential to observe. The process specifications of this product need to specify the method of preparation, the geometry of the materials used, and the sequence of steps. Each step, heat, duration, and proportion of materials used are all key. As for the identification (product parameters), it should be marked with its properties, such as color, taste, and state, as well as its purity and the geometry of the impurities contained, which are all related to product quality. In this way, the process specification and identification (product parameters) are necessary to make the output of this Ethyl 4-Hydroxy-3-Iodobenzoate meet the requirements and be of high quality.

Preparation Method

To prepare Ethyl 4-Hydroxy-3-Iodobenzoate, prepare the raw materials first. Take 4-hydroxybenzoic acid, use an appropriate amount of ethanol as a solvent, add concentrated sulfuric acid as a catalyst, heat and reflux, and perform an esterification reaction to obtain Ethyl 4-Hydroxybenzoate. This step requires moderate temperature control and appropriate duration to avoid side reactions.
Then, the obtained Ethyl 4-Hydroxybenzoate is placed in a reaction kettle with an appropriate amount of iodine and an oxidizing agent. According to a specific ratio, select an appropriate solvent, and control the reaction temperature and duration. After iodization, Ethyl 4-Hydroxy-3-Iodobenzoate is obtained.
After the reaction is completed, the product is purified by extraction, distillation, recrystallization and other methods. When extracting, select the appropriate extractant, and the distillation temperature is accurately controlled. The appropriate solvent and temperature are selected for recrystallization to ensure the purity of the product. The whole preparation process needs to strictly abide by the operating specifications and control the conditions of each link to obtain the best quality Ethyl 4-Hydroxy-3-Iodobenzoate.

Chemical Reactions & Modifications

Modern chemistry has advanced, and the study of Ethyl 4-Hydroxy-3-Iodobenzoate has deepened. Although the chemical reaction initially followed the old rules, it has been felt that there is something to be improved over time. In the past, the reaction method, or the yield was not ideal, or the by-products were complicated, which affected the quality.
Today's scholars are dedicated to thinking about changes and seeking new ones. Some take changing the reaction conditions as the path, adjust the temperature and pressure, so that the molecules collide in an orderly manner, and promote the reaction to be optimal; there are also easier catalysts, find efficient substances, reduce the activation energy, and increase the reaction rate. After various explorations, the reaction yield gradually increased, and the product purity was also good. This is the work of chemical change, which makes the production of Ethyl 4-Hydroxy-3-Iodobenzoate increasingly sophisticated, laying the foundation for various applications.

Synonyms & Product Names

Ethyl 4-Hydroxy-3-Iodobenzoate, this thing is also its synonym and trade name, which is quite important in the academic world. Ancient scholars, in the name of the name of the thing, must be accurate. This compound, or another name, to meet the needs of different situations. The name of the product, the merchant to recognize its characteristics, then identify and promote the order.
Considering the classics, the name of the chemical substance is often different due to the region and habit. However, its essence, the meaning is the same. Ethyl 4-Hydroxy-3-Iodobenzoate, with a specific molecular structure and chemical properties, although the synonym and the trade name are different, they all point to this thing.
In the process of chemical research, it can avoid the risk of confusion and help researchers communicate smoothly. It is the way of learning to find traces of it in ancient books or to study the evolution of its title in modern documents. Aliases and trade names, like the logo of the boat, lead scholars to the Wang Yang of chemical research and reach the other side of truth.

Safety & Operational Standards

Safety and Handling Specifications for Ethyl 4 - Hydroxy - 3 - Iodobenzoate
Ethyl 4 - Hydroxy - 3 - Iodobenzoate is an important chemical product, and its safety and handling specifications must not be ignored.
When storing, choose a dry, cool and well-ventilated place. Because it may be sensitive to temperature and humidity, if the environment is not good, it is easy to cause quality changes. Do not co-store with oxidants, acids, etc., to prevent dangerous chemical reactions.
When operating, operators must strictly follow the specifications. Wear appropriate protective clothing, such as lab clothes and protective gloves, to avoid direct contact with the skin. Eye protection is also indispensable. You need to wear goggles to prevent accidental splashing and damage.
During use, ensure that the operating environment is well ventilated. If used in a poorly ventilated place, its volatile gases may endanger human health. When taking it, the action should be cautious, and the amount should be accurately measured according to the required dosage. Do not dump it at will to avoid waste and pollution.
If you accidentally come into contact with this chemical, those who come into contact with the skin should immediately rinse with a large amount of water, and then seek medical attention as appropriate; if it splashes into the eyes, you need to rinse with a large amount of flowing water immediately and seek medical treatment quickly.
When discarding and disposing, it should also be implemented in accordance with relevant regulations. Do not discard at will to avoid pollution to the environment. It should be handed over to a professional waste disposal facility for proper disposal.
Only by strictly following the above safety and operating practices can the safety of Ethyl 4 - Hydroxy - 3 - Iodobenzoate in storage, use and disposal be ensured, which not only protects the health of people, but also safeguards the environment from damage.

Application Area

Ethyl 4 - Hydroxy - 3 - Iodobenzoate is also a wonderful thing to be transformed. Its application in the field of application, in the way of cultivation, can be used as the foundation of research and development of special effects, so as to save people from diseases and pains. In the field of materials, it can improve the quality of fine materials, improve their characteristics, or improve their performance, or increase their light energy. In the process of synthesis, Ethyl 4 - Hydroxy - 3 - Iodobenzoate is an important part of the process, and it is a new material. Therefore, Ethyl 4 - Hydroxy - 3 - Iodobenzoate is a micro-technology, but it is of great use in many fields. It is also important to promote the development of science and technology, benefit life, and transform the world.

Research & Development

To taste the way of scientific research, it is important to explore and innovate. Today there is a thing called Ethyl 4 - Hydroxy - 3 - Iodobenzoate, and we have devoted ourselves to studying it. At the beginning, we explored the method of its synthesis. After many attempts, we improved the process and gradually increased the yield. Then, study its properties, observe its reaction under different conditions, and clarify its characteristics. We also think about its application, and find opportunities in the field of medicine, which is expected to add new paths to the treatment of diseases. We make unremitting efforts to use this product to make achievements, promote the progress of scientific research, and benefit the world. Although the road ahead is long, we will uphold our original intention and unswervingly make this research achievement carry forward and contribute to the development of scientific research.

Toxicity Research

The chemical industry is related to people's livelihood, but the study of poisons in it should not be careless. Today there is a thing called Ethyl 4-Hydroxy-3-Iodobenzoate, and the investigation of its toxicity is quite important.
We are careful to explore its toxicity. After various tests, observe its impact on living things. Observe its interaction with the body, or cause biochemical changes. Observe its entry into the body, circulation and reach various places, or disturb the organs.
Although this substance is used in industry or has its uses, its toxicity should not be ignored. When the dose threshold is carefully investigated, the degree of harm should be clearly understood. In this way, it is possible to use the benefits to avoid their harm, maintain the safety of the living, protect the environment, and make the chemical industry stable and harmless.

Future Prospects

I have dedicated myself to the research of Ethyl 4 - Hydroxy - 3 - Iodobenzoate, and I have thought about its future prospects. Looking at today's world, technology is new and chemistry is advanced, and this product also has extraordinary potential.
Ethyl 4 - Hydroxy - 3 - Iodobenzoate is used in pharmaceutical research and development, or it can be the cornerstone of new drug creation, helping doctors overcome difficult diseases and save patients from pain. In the field of materials science, it may also emerge, giving materials unique properties, used in high-end manufacturing, and promoting the prosperity of industry.
With the deepening of research, the method of synthesis may be more refined, the cost is reduced, and the yield is increased. In this way, it is more widely used and adds to many industries. I firmly believe that over time, Ethyl 4 - Hydroxy - 3 - Iodobenzoate will be able to shine and paint a magnificent picture for the future development.

Where to Buy Ethyl 4-Hydroxy-3-Iodobenzoate in China?

As a trusted Ethyl 4-Hydroxy-3-Iodobenzoate manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading Ethyl 4-Hydroxy-3-Iodobenzoate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of Ethyl 4-hydroxy-3-iodobenzoate?

Ethyl 4-hydroxy-3-iodobenzoate (ethyl 4-hydroxy-3-iodobenzoate) is an important compound in the field of organic synthesis and has a wide range of uses.
First, in the field of medicinal chemistry, this compound is a key intermediate. The presence of iodine atoms and hydroxyl groups endows it with unique reactivity and biological activity. Through a series of organic reactions, it can be structurally modified and derived to synthesize many drug molecules with potential biological activities. For example, it can react with specific amines, alcohols and other reagents to construct complex chemical structures to develop therapeutic drugs for specific diseases, such as antibacterial, anti-inflammatory and anti-tumor drugs.
Second, in the field of materials science, Ethyl 4-hydroxy-3-iodobenzoate also shows potential application value. Because of the ester group, hydroxyl group and iodine atoms contained in its chemical structure, it can participate in the synthesis and modification process of materials. For example, it can be introduced into the structure of polymers to improve the properties of polymer materials by means of its reactivity, such as improving the solubility, thermal stability and optical properties of materials, so as to be used in the preparation of new functional materials, such as photoelectric materials, sensing materials and other fields.
Third, in the study of organic synthetic chemistry, Ethyl 4-hydroxy-3-iodobenzoate as an important starting material or intermediate, and is widely used in the research and method development of various organic reactions. Its diverse functional groups provide rich reaction checking points for organic chemists, which can be used to explore novel reaction paths and synthesis strategies, and promote the development and progress of organic synthetic chemistry.

What are the synthetic methods of Ethyl 4-hydroxy-3-iodobenzoate?

The methods for preparing Ethyl 4-hydroxy-3-iodobenzoate (ethyl 4-hydroxy-3-iodobenzoate) are as follows.
One of them can be started from ethyl 4-hydroxy benzoate. First, an appropriate iodine substitution reagent, such as iodine elemental ($I_ {2} $), works synergistically with a suitable oxidant. Common oxidants such as hydrogen peroxide ($H_ {2} O_ {2} $), under mild reaction conditions, introduce iodine atoms at the hydroxyl ortho-position of ethyl benzoate. This reaction needs to be controlled by the reaction temperature, the amount of reagent and the reaction time. If the temperature is too high, side reactions may breed; if the amount of reagent is inappropriate, the reaction may be incomplete.
Second, 3-iodine-4-methoxybenzoic acid can also be used as the starting material. The methoxy group is first treated with a suitable demethylation agent, such as boron tribromide ($BBr_ {3} $), so that the methoxy group is converted into a hydroxyl group, and then the esterification reaction is carried out with ethanol under acid catalysis. The acid catalyst can be concentrated sulfuric acid or p-toluenesulfonic acid. During the reaction, attention should be paid to the reversibility of the esterification reaction. The generated water can be removed to promote the reaction to move in the direction of ester formation.
Third, 4-hydroxy-3-nitrobenzoic acid is used as the starting material. The nitro group is first converted into an amino group through a reduction reaction, such as iron and hydrochloric acid as a reduction system. After 4-hydroxy-3-aminobenzoic acid is obtained, it is then reacted with sodium nitrite and hydrochloric acid to form a diazonium salt, then reacted with potassium iodide to introduce iodine atoms, and finally esterified with ethanol to obtain the target product. There are many steps in this path, but the reaction conditions of each step are relatively mature, and the reaction process and product purity of each step need to be carefully controlled.

What are the physical properties of Ethyl 4-hydroxy-3-iodobenzoate?

Ethyl 4-hydroxy-3-iodobenzoate is an organic compound, its physical properties are quite unique. This compound is mostly solid at room temperature, and its appearance may be white to light yellow crystalline powder. Because it contains specific atoms and functional groups, its appearance has this characteristic.
As far as the melting point is concerned, it is about a specific temperature range. The specific value varies slightly according to the experimental conditions. Usually within a certain temperature range, when heated, the lattice structure is damaged, the molecule is energized, and it changes from solid to liquid.
In terms of solubility, it has a certain solubility in organic solvents such as ethanol and acetone. This is due to the existence of intermolecular forces between organic solvent molecules and Ethyl 4-hydroxy-3-iodobenzoate molecules, such as van der Waals force, hydrogen bond, etc., which can promote dissolution. However, the solubility in water is not good, because although there are hydroxyl groups in the molecule that can form hydrogen bonds with water, the ester group and the iodine atom have strong hydrophobicity, which weakens its solubility in water as a whole.
The compound has a certain density. Compared with water, due to the molecular composition and accumulation mode, the density may be greater than or less than water, which affects its distribution in the mixed system. In addition, Ethyl 4-hydroxy-3-iodobenzoate also needs to pay attention to the light and thermal stability. Light, high temperature or cause decomposition, isomerization and other reactions to affect its chemical purity and properties. Therefore, this physical property should be considered when storing and using, and it should be properly stored to avoid its deterioration. To ensure stable performance in organic synthesis, drug development and other fields.

What are the chemical properties of Ethyl 4-hydroxy-3-iodobenzoate?

Ethyl + 4 - hydroxy - 3 - iodobenzoate, ethyl 4 - hydroxy - 3 - iodobenzoate, is an organic compound with unique chemical properties.
First, it has the properties of esters. Esters can undergo hydrolysis reactions catalyzed by acids or bases. Under acidic conditions, 4-hydroxy-3-ethyl iodobenzoate is hydrolyzed to generate 4-hydroxy-3-iodobenzoic acid and ethanol; under basic conditions, hydrolysis generates 4-hydroxy-3-iodobenzoate and ethanol. This hydrolytic property is often used to construct or break carbon-oxygen bonds in organic synthesis, providing a way for the synthesis of organic compounds with specific structures.
Second, there are hydroxyl and iodine atoms on its phenyl ring. Hydroxyl groups have certain nucleophilic properties and can participate in many nucleophilic substitution reactions. For example, with halogenated hydrocarbons under the action of bases, corresponding ethers can be formed. Iodine atoms are good leaving groups. Under the catalysis of metals, coupling reactions can occur, such as carbon-carbon bond coupling with compounds containing unsaturated bonds under the catalysis of metals such as palladium, which greatly expands its application in the field of organic synthesis and is conducive to the construction of complex carbon skeleton structures.
Third, due to the presence of hydroxyl groups, hydrogen bonds can be formed between molecules. Hydrogen bonds affect the physical properties of substances, such as melting points and boiling points are relatively high, and the solubility in some solvents is affected by hydrogen bonds. In polar solvents, the solubility or hydrogen bonds are enhanced, which is of great significance for their separation, purification and reaction medium selection.
Fourth, ethyl 4-hydroxy-3-iodobenzoate has certain chemical stability, but under extreme conditions such as strong oxidizing agent and high temperature, the molecular structure may be destroyed. At the same time, the electron cloud distribution of the benzene ring changes due to the substitution of hydroxyl and iodine atoms, which affects the electrophilic substitution reaction activity and check point selectivity on the benzene ring.

What are the precautions for Ethyl 4-hydroxy-3-iodobenzoate during storage and transportation?

Ethyl + 4 - hydroxy - 3 - iodobenzoate is an organic compound. During storage and transportation, many matters need to be paid attention to.
First storage environment. Be sure to choose a cool, dry and well-ventilated place. This compound is sensitive to humidity and temperature. High temperature and humid environment can easily cause it to deteriorate. The temperature should be controlled within a specific range to prevent thermal decomposition. If placed in a cool warehouse, keep away from heat sources and open flames to ensure safety and stability.
Furthermore, when storing, it needs to be isolated from air. Because some of its structure may react with oxygen in the air, resulting in quality damage. It can be stored in a sealed container, such as an airtight glass bottle or a container with a sealing gasket, to prevent air intrusion.
When shipping, the packaging must be solid and reliable. It needs to be wrapped with suitable materials to prevent vibration and collision from causing the container to burst. If filled with foam, cotton and other cushioning materials, the outer packaging should be clearly marked, indicating its properties and precautions.
In addition, this compound may have certain toxicity and irritation. Personnel should avoid direct contact, whether during storage or transportation. Wear appropriate protective equipment, such as gloves, goggles and protective clothing, during operation to prevent accidental contact with skin or eyes and cause injury. In case of inadvertent contact, rinse with plenty of water immediately and seek medical attention in time.
In conclusion, for the storage and transportation of Ethyl + 4 - hydroxy - 3 - iodobenzoate, care must be taken in terms of environment, packaging and personnel protection to ensure its quality and safety.