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What is the chemical structure of Ethyl N-acetyl-3,5-diiodotyrosinate?
Ethyl + N - acetyl - 3,5 - diiodotyrosinate, this is an organic compound containing ethoxy, acetamide and two iodine atoms attached to the tyrosine-derived ester structure. Its chemical structure can be analyzed as follows:
The root of this compound is derived from tyrosine, which is an amino acid with phenolic hydroxyl groups. In Ethyl + N - acetyl - 3,5 - diiodotyrosinate, the carboxyl group of tyrosine reacts with ethanol to form an ester, resulting in an ethoxy group (-OCH -2 CH), which is an ester bond connection.
The tyrosine amino group is modified by acetylation, that is, the amino group is connected to the acetyl group (CH < CO -) to form the N-acetyl group structure.
Furthermore, the two hydrogen atoms at the phenolic hydroxyl ortho-position are replaced by iodine atoms, and iodine atoms are introduced at the 3rd and 5th positions to obtain the 3,5-diiodine structure.
In summary, the chemical structure of Ethyl + N-acetyl-3,5-diiodotyrosinate is derived from tyrosine and is composed by the modification of ester bonds, acetyl amino groups and diiodine substituents. This unique structure may give it specific physical, chemical and biological activities.
What are the main uses of Ethyl N-acetyl-3,5-diiodotyrosinate?
Ethyl + N - acetyl - 3,5 - diiodotyrosinate (ethyl - N - acetyl - 3,5 - diiodotyrosine ester) is very useful in the field of medicine and scientific research.
In medicine, first, it is related to the preparation of thyroid-related drugs. The synthesis of thyroid hormones often involves such compounds. Its structure is similar to that of thyroid hormone intermediates, which can participate in the process of simulating or regulating thyroid hormone synthesis. Physicians can study its metabolic transformation in the body to understand the mechanism of thyroid hormone imbalance, and then develop precise treatment agents. Second, it has potential medicinal activity. Or it can regulate the biochemical reaction path of the body and play a therapeutic role in specific diseases. For example, for some diseases caused by hormone regulation disorders, this compound may interact with receptors in the body to restore hormone balance and achieve therapeutic purposes.
In the field of scientific research, it is an important chemical tool. Scientists often use this as a raw material to synthesize new compounds with specific structures and functions. By modifying and modifying its structure, exploring the relationship between structure and activity provides key clues for the design and development of new drugs. Furthermore, in biochemical experiments, it can be used as a tracer substance. Due to its special structure, it can be accurately tracked in complex biological systems, helping researchers to clarify the specific process and metabolic path of biochemical reactions and deepen their understanding of life processes.
What is the preparation method of Ethyl N-acetyl-3,5-diiodotyrosinate?
Ethyl + N-acetyl-3,5-diiodotyrosinate (ethyl-N-acetyl-3,5-diiodotyrosine ester) is prepared as follows:
First take an appropriate amount of tyrosine and treat it with an acetylating agent to make it aminoacetylated to generate N-acetyl tyrosine. This process requires mild reaction conditions to avoid affecting other functional groups.
Next, N-acetyl tyrosine is dissolved in suitable solvents, such as polar organic solvents, such as dichloromethane, N, N-dimethylformamide, etc., which help to dissolve the reaction substrate and proceed with subsequent reactions. Then, slowly add an iodizing reagent to the reaction system, such as iodine in combination with an appropriate oxidizing agent, such as hydrogen peroxide, etc., so that the 3 and 5 positions of the tyrosine benzene ring are iodized to generate N-acetyl-3,5-diiodotyrosine. In the meantime, the reaction process should be closely monitored, and thin-layer chromatography can be used to ensure that the iodization reaction reaches the desired level and does not overreact.
Then N-acetyl-3,5-diiodotyrosine is esterified with ethanol in the presence of an acidic catalyst. Commonly used acidic catalysts such as concentrated sulfuric acid and p-toluenesulfonic acid need to be carried out under heating and refluxing conditions to promote the full reaction of the two to form Ethyl + N-acetyl-3,5-diiodotyrosinate.
After the reaction is completed, the reaction mixture is treated with conventional separation and purification methods, such as extraction, column chromatography, etc., to remove unreacted raw materials, by-products and catalyst impurities, and finally obtain pure Ethyl + N-acetyl-3,5-diiodotyrosinate products.
What are the physical and chemical properties of Ethyl N-acetyl-3,5-diiodotyrosinate?
Ethyl + N - acetyl - 3,5 - diiodotyrosinate (ethyl - N - acetyl - 3,5 - diiodotyrosine ethyl ester), this substance is an organic compound, its physical and chemical properties are as follows:
Looking at its properties, under room temperature, or white to light yellow crystalline powder, like a fine frost powder, light and loose.
As for the melting point, it is usually in a certain temperature range, about [X] ° C to [X] ° C. When heated, it gradually melts from the solid state to the liquid state. This process is smooth and orderly, just like ice and snow meeting warm sun, slowly melting.
In terms of solubility, it exhibits good solubility in organic solvents such as ethanol and chloroform, just like fish entering water, it can quickly disperse and dissolve; while in water, the solubility is poor, like oil floating in water, it is difficult to blend.
In terms of stability, under conventional environmental conditions, it is quite stable and can withstand the passage of time without changing its properties; however, if placed in an environment with high temperature, strong light or the presence of specific chemical reagents, chemical reactions may occur, causing its structure and properties to change, just like beautiful jade under severe grinding, it will inevitably be damaged.
In addition, its molecular structure is endowed with unique chemical activity due to specific groups such as iodine atoms, which can participate in a variety of organic synthesis reactions, and has potential application value in medical chemistry and other fields. It is like a hidden treasure in the treasure house, waiting for people to explore and use.
What is the price range of Ethyl N-acetyl-3,5-diiodotyrosinate in the market?
Ethyl + N - acetyl - 3,5 - diiodotyrosinate is an organic compound, but it is difficult to determine the exact price range in the market. The price often varies due to many factors, such as purity, production scale, market supply and demand, production process and technology, and differences in sales regions.
If its purity is very high, and it is used for specific high-end scientific research or pharmaceutical preparation, due to strict quality control, complex production process, high cost, price may be quite expensive. On the contrary, if the purity is slightly lower, it is used for general research or industrial use, and the price may be relatively close to the people.
Furthermore, the scale of production is also the key. In large-scale production, due to the scale effect, the unit cost may be reduced, and the price will also decrease; while in small batch production, the cost is difficult to decrease, and the price will be higher.
Market supply and demand also have a huge impact on its price. If the market has strong demand for this compound and limited supply, its price will rise; if the demand is low and the supply is sufficient, the price will fall.
Production processes and technologies also affect its cost and price. Advanced processes may improve production efficiency and reduce costs, but research and development and adoption of new technologies also require investment.
The differences in sales regions cannot be ignored. Different regions have different economic levels, tax policies, and logistics costs, which will all lead to different prices.
In summary, Ethyl + N - acetyl - 3,5 - diiodotyrosinate is difficult to determine in the market price range, and it needs to be comprehensively judged according to the above factors.