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What are the main physiological functions of L-3,3,5-triiodothyronine, Free Acid?
L-3,3,5-triiodothyronine free acid is the key to the physiological function of the human body. Its primary function is to regulate the basal metabolic rate. Just like controlling the speed of water flow in a boat, this substance can make the rhythm of biochemical reactions in the cell slow or fast. By affecting energy production and consumption, it can ensure that the body maintains proper operation in a resting state, such as constant body temperature and stable organ function.
Furthermore, it has a profound impact on the development of the nervous system. In the embryo and early childhood, the nervous system is in urgent need of nourishment like a new bud. This substance is like manna, which is indispensable for the proliferation, differentiation and synaptic formation of nerve cells, and is the basis for building a sound nervous system. Without it, the nervous system will develop or be blocked, resulting in cognitive, behavioral and other disorders.
Repeat, it also has a significant effect on the cardiovascular system. It can regulate the contractility and heart rate of the heart, if the helmsman controls the direction of the ship. Moderate levels can make the heart pump blood smoothly and maintain blood circulation stability. Once its level is abnormal, the cardiac workload or imbalance, or arrhythmia, abnormal heart function and other diseases.
In addition, it also plays an important role in lipid metabolism. It can promote lipolysis and oxidation, help the body convert fat into energy, and avoid excessive accumulation of lipids in the body, which is of great significance for maintaining normal blood lipid levels.
In short, L-3,3,5-triiodothyronine free acid is small, but it is a hub for many key physiological functions of the human body, affecting the whole body and maintaining the health and balance of the body.
What is the normal level range of L-3,3,5-triiodothyronine, Free Acid in the human body?
L-3,3,5-triiodothyronine free acid, in the human body, its normal blood value range is quite critical. This substance plays an important role in the human endocrine system and is related to many physiological processes such as metabolism, growth and development.
The normal blood value range is about 2.3-4.2 pg/mL. This value is not static and may vary slightly due to factors such as detection methods, testing equipment and individual differences. In clinical diagnosis, doctors need to synthesize the patient's symptoms, medical history and other relevant test results to accurately determine the thyroid function status.
If the blood value deviates from the normal range, or suggests abnormal thyroid function. Elevated blood value, or seen in hyperthyroidism, patients or sweating, palpitations, wasting, etc.; reduced blood value, or hypothyroidism, patients or fatigue, chills, lethargy, etc. Therefore, clear the normal blood value range of this substance is of great significance for the early diagnosis and treatment of thyroid diseases.
What is the clinical significance of L-3,3,5-triiodothyronine, Free Acid testing?
The clinical significance of L-3,3,5-triiodothyronine free acid detection is related to many aspects of human health. This test can help doctors to understand the functional status of the thyroid gland. Thyroid gland, in the human endocrine system, plays a key position, its secretion of thyroid hormones have a significant impact on metabolism, growth and development and nervous system function.
L-3,3,5-triiodothyronine free acid, is an important component of thyroid hormone activity. If its detection value is elevated, or due to hyperthyroidism. When hyperthyroidism occurs, thyroid hormones are secreted too much, and the body's metabolism is hyperactive. Patients often experience palpitations, sweating, weight loss, and hand shaking. At this time, the detection of this indicator increases, which can provide a key basis for the diagnosis of hyperthyroidism.
On the contrary, if the detection value decreases, it may indicate hypothyroidism. Thyroid hormone secretion is insufficient during hypothyroidism, the body's metabolism slows down, and patients may have fatigue, chills, drowsiness, and myxedema. This indicator is also an important clue for the diagnosis of hypothyroidism.
In addition, in some non-thyroid diseases, such as serious systemic diseases, drug effects, etc., this indicator may also be abnormal. Therefore, the detection of L-3,3,5-triiodothyronine free acid is of indispensable significance in clinical diagnosis, disease monitoring and the formulation and adjustment of treatment plans, which can help doctors accurately judge the condition and give patients appropriate treatment.
What are the detection methods of L-3,3,5-triiodothyronine, Free Acid
To detect L - 3% 2C3% 2C5 - triiodothyronine% 2C Free Acid, there are three methods.
One is immunoassay. This is a commonly used method, which measures the content of antibodies based on the specific binding of antibodies to the substance. Commonly used methods such as radioimmunoassay, which labels antigens with radionuclides, compete with the antigens in the sample to bind the limited amount of antibodies, and measure the radioactivity intensity to know the amount of antigens in the sample. Although sensitive and specific, there is a risk of radioactive hazards. Enzyme-linked immunosorbent assays are also of this type. The operation of labeling antigens or antibodies with enzymes and measuring the amount of antigens by the color change of the reaction between enzymes and substrates is simple and safe.
The second is high-performance liquid chromatography. This method separates the mixture by the difference in the distribution coefficient of the solute between the stationary phase and the mobile phase. With appropriate mobile phase and stationary phase, L-3% 2C3% 2C5 - triiodothyronine% 2C Free Acid can be separated from impurities, and its content can be measured by a detector. It can separate complex mixtures with accurate results, but the instrument is expensive and the operation requires professional skills.
The third is mass spectrometry. This is based on the difference in the mass-charge ratio of ions. The sample is ionized first, and the ions are separated by a mass analyzer to measure the strength of ions with different mass-charge ratios by a detector. The molecular weight and structure of the substance can be determined, which is sensitive and specific, but the instrument is complicated and the analysis cost is high.
L-3,3,5-triiodothyronine, Free Acid Levels May Cause Which Diseases
L-3,3,5-triiodothyronine free acid, if its level is abnormal, can cause many diseases. This is an important hormone in the human body and plays an indispensable role in key physiological processes such as metabolism and growth and development.
If its level is elevated, it may cause hyperthyroidism. Patients often have symptoms such as palpitations, sweating, weight loss, hunger, hand shaking, insomnia and emotional irritability. Because of excessive thyroid hormones, the body's metabolism is hyperactive and energy expenditure is intensified.
And the level is reduced, or it may cause hypothyroidism. Patients may show chills, fatigue, lethargy, weight gain, constipation, dry and rough skin, memory loss and other manifestations. This is due to the lack of thyroid hormones and the slowdown of the body's metabolism.
In addition, abnormal levels of this hormone can affect the fetal nervous system and intellectual development in pregnant women, or hinder growth and development in children, causing nerds, etc. Therefore, maintaining normal levels is essential for human health.