L 3 4 4 Hydroxy 3 Iodophenoxy 3 5 Diiodophenyl Alanine
Iodobenzene

L-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)alanine

Fengxi Chemical

Specifications

HS Code

851741

Chemical Formula C15H12I3NO4
Molecular Weight 650.97 g/mol
Appearance White to off - white powder
Solubility Slightly soluble in water, more soluble in organic solvents like ethanol
Pka Around 2.2 (carboxyl group) and 9.2 (amino group)
Melting Point Approximately 235 - 240 °C
Density N/A (powder)
Stability Stable under normal conditions, but sensitive to light and air
Odor Odorless
Chemical Formula C15H12I3NO4
Molar Mass 650.975 g/mol
Appearance Typically a solid
Solubility In Water Low solubility
Pka Value Related to the carboxylic acid and phenolic groups
Boiling Point Decomposes before boiling
Melting Point Specific value would require literature search
Optical Activity Exists as an L - isomer (chiral)
Reactivity Can react with reagents that target carboxylic acid, phenol groups
Stability Stable under normal storage conditions away from light and heat
Chemical Formula C15H12I3NO4
Molecular Weight 655.97 g/mol
Iupac Name 2-amino-3-[3,5-diiodo-4-(4-hydroxy-3-iodophenoxy)phenyl]propanoic acid
Appearance Solid (usually white to off - white powder)
Solubility Slightly soluble in water, more soluble in organic solvents like DMSO
Pka Carboxyl group pKa ~2 - 3, amino group pKa ~9 - 10, phenolic - OH pKa ~9 - 10
Boiling Point Decomposes before boiling
Melting Point 190 - 194 °C
Density Estimated around 2.5 - 3.0 g/cm³
Stability Stable under normal conditions, but sensitive to light and air
Chemical Formula C15H12I3NO4
Molar Mass 650.97 g/mol
Appearance White to off - white powder
Solubility In Water Poorly soluble
Solubility In Organic Solvents Soluble in some organic solvents like DMSO
Pka Typically in the range related to phenolic and carboxylic acid groups
Boiling Point Decomposes before boiling
Melting Point Approximately 235 - 240 °C
Stability Stable under normal storage conditions, but sensitive to light and air
Optical Activity Exists as an L - isomer with optical activity
Packing & Storage
Packing 100 - gram pack of L - 3-(4-(4 - hydroxy - 3 - iodophenoxy)-3,5 - diiodophenyl)alanine in sealed container.
Storage Store “L - 3 - (4 - (4 - hydroxy - 3 - iodophenoxy)-3,5 - diiodophenyl)alanine” in a cool, dry place, away from direct sunlight. Keep it in a tightly sealed container to prevent moisture absorption and potential chemical reactions. Store it separately from incompatible substances to avoid contamination. Follow local safety regulations for chemical storage.
Shipping Shipment of "L-3-(4-(4-hydroxy-3-iodophenoxy)-3,5 -diiodophenyl)alanine" requires careful handling. It should be shipped in well - sealed containers, following chemical transport regulations, ensuring safety during transit.
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L-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)alanine L-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)alanine L-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)alanine
General Information
Frequently Asked Questions
What is the chemical structure of L-3- (4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl) alanine?
The chemical structure of L-3- (4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl) alanine is also quite complicated. This compound is based on alanine, and its β-carbon is connected with a substituted phenyl group. The 3rd and 5th positions of the phenyl group each have an iodine atom, and the 4th position is connected with a 4-hydroxy-3-iodophenoxy group.
Looking at this structure, alanine has an amino group and a carboxyl group. It is an important checking point for biological activity and is closely related to the composition of peptides and proteins. The placement of many iodine atoms on the benzene ring affects its lipophilicity and spatial structure, or its pharmacological activity and metabolic pathway have significant effects. The connection of 4-hydroxy-3-iodophenoxy groups increases the complexity of its chemical properties. Hydroxyl groups can involve the formation of hydrogen bonds and affect intermolecular interactions.
Such a structure is the key to research in organic synthesis, drug development and other fields. Because of its special structure or unique biological activity, it can become the basis for the creation of new drugs. Although the structure is complex, it is clear that its chemical structure is mentioned before exploring its properties and functions. It is of great significance to the study of chemistry, biology and other disciplines.
What are the main uses of L-3- (4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl) alanine
L-3- (4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl) alanine, an organic compound, has important uses in medicine and scientific research.
In medicine, it is often used as an intermediate in thyroid hormone synthesis. Thyroid hormones play a key role in human metabolism, growth and development, and the normal operation of the nervous system. This compound can participate in the synthesis of thyroid hormones, thereby maintaining normal thyroid function. It plays an indispensable role in the research and treatment of thyroid diseases. For example, the pathogenesis of some thyroid dysfunction diseases is related to thyroid hormone synthesis, and this compound can provide an important research direction for exploring treatment options.
In the field of scientific research, because of its special chemical structure, it has unique physical and chemical properties, which can be used for the study of organic synthesis reactions. Chemists can explore the synthesis path of new organic compounds by modifying and modifying their structures, laying the foundation for the development of new materials with specific properties. Furthermore, in pharmaceutical chemistry research, it may be used as a lead compound, and new drugs with better efficacy and less side effects can be developed through structural optimization. It is like a key "key" in the field of medicine and scientific research, opening up new doors for many research and applications.
What are the physical properties of L-3- (4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl) alanine
L-3- (4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl) alanine, which is an organic compound. Looking at its physical properties, at room temperature, or in a solid state, because of its molecular structure, there are many polar groups and benzene ring structures, and the strong intermolecular force causes it to have a high melting point. However, the exact melting point value still needs to be accurately determined by experiments.
As for its solubility, because the molecule is rich in polar groups such as hydroxyl groups, it may have a certain solubility in polar solvents such as water and alcohol solvents. Hydroxyl groups can form hydrogen bonds with water molecules to increase their solubility in water. However, due to the large number of iodine atoms in the molecule and the strong hydrophobicity of the benzene ring structure, its solubility in non-polar solvents, such as alkane solvents, may be low.
Its appearance may be white to light yellow powder, which is due to the conjugate structure of the benzene ring and the iodine atom, or the specific absorption and scattering of light. At the same time, the compound may have certain stability. Due to the electronic effect of the conjugate system of the benzene ring and the iodine atom, the molecular structure can be stabilized. However, in case of extreme conditions such as high temperature, strong acid and base, or chemical reactions, its structure can be changed. In short, the physical properties of this compound are determined by its unique molecular structure, and it has far-reaching impact on its application in various fields.
What is the synthesis method of L-3- (4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl) alanine
For L-3- (4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl) alanine, the method of synthesis is as follows.
First take appropriate starting materials, such as iodine-containing benzene compounds, and modify them. In the ancient method, when carefully selecting the reactants to have suitable active groups. If you want to obtain the 4-hydroxy-3-iodophenoxy moiety, you can make iodophenols and suitable halogenated alkoxy compounds in a suitable alkaline environment, in a state called "mutual compatibility" in the ancient method, nucleophilic substitution reaction occurs. The base, or potassium carbonate or the like, is heated and stirred in an organic solvent, such as acetone, to make the two blend and react to obtain a product containing this specific oxygen group.
For the 3,5-diiodophenyl moiety, or starting from benzene, iodine substitution reagent, such as iodine, and appropriate oxidant, such as nitric acid, according to the ancient "principle of combination", the benzene ring is iodized at a specific position to obtain 3,5-diiodobenzene.
Then, the substance containing 4-hydroxy-3-iodophenoxy is connected to 3,5-diiodophenyl, or by means of acylation, condensation and other reactions. Reintroducing the alanine part may be achieved by condensation reaction with alanine derivatives. When condensing, a suitable condensing agent, such as carbodiimide, needs to be selected to promote the combination of the two. During the reaction process, temperature, time, and the proportion of reactants need to be precisely controlled. Just like the ancient alchemy method, the temperature and the proportion of ingredients are related to success or failure. After multi-step reaction, separation, purification and other processes, L-3- (4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl) alanine can be obtained.
What is the market outlook for L-3- (4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl) alanine?
L-3- (4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl) alanine, which is a rather complex organic compound. Looking at its market prospects, it actually involves many aspects.
In the field of medicine, many iodine-containing organic compounds have shown unique roles in drug development. The introduction of iodine atoms can change the physical and chemical properties of the compound, such as fat solubility, stability, etc., and then affect its biological activity. This compound may have potential medicinal value and can be used as a drug lead compound. If its pharmacological activity can be deeply explored and modified, or new drugs can be developed, such as for the treatment of specific diseases, the market potential is huge.
In the field of materials science, iodine-containing organic compounds may come in handy in the preparation of some functional materials. For example, they may be used to prepare materials with special optical and electrical properties. If the compound can exhibit unique optical properties, such as fluorescence, photochromic, etc., it may find applications in the field of optical materials, providing new ideas for the development of new display materials, sensor materials, etc. The market prospect is also optimistic.
However, its marketing activities also face challenges. Synthesis of such complex compounds may require complicated steps and high cost, which hinders large-scale production. And in terms of application research, a lot of manpower and material resources need to be invested in in-depth exploration to clarify its exact performance and application scenarios. Only by overcoming the problems of synthesis cost and application research can this compound gain a place in the market and realize its potential market value.