M-Fluoroiodobenzene

Fengxi Chemical

Specifications

HS Code	996798
Chemical Formula	C6H4F I
Molecular Weight	222.00
Appearance	Colorless to light yellow liquid
Boiling Point	185 - 187 °C
Density	1.854 g/mL at 25 °C
Solubility In Water	Insoluble
Flash Point	77 °C
Refractive Index	1.619 (20 °C)

As an accredited M-Fluoroiodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100 mL of M - fluoroiodobenzene in a sealed, labeled glass bottle for chemical packaging.
Storage	M - fluoroiodobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points. Keep it in a tightly sealed container to prevent vapor leakage. Since it may react with oxidizing agents, store it separately from such substances. Avoid exposure to direct sunlight to maintain its chemical stability.
Shipping	M - fluoroiodobenzene is shipped in sealed, corrosion - resistant containers. It's transported under strict safety protocols, avoiding heat, direct sunlight, and incompatible substances to ensure safe delivery.

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General Information

Historical Development

M - Fluoroiodobenzene is also an organic compound. It has become increasingly important in the field of chemical synthesis. Looking back to the past, chemists have studied the way of organic synthesis, hoping to expand the boundaries of material creation. At the beginning, synthesizing this compound was difficult, the reaction conditions were harsh, and the yield was also low.
However, chemists persevered and explored it carefully over the years. Improve the reaction medium, optimize the choice of catalyst, and eventually improve the synthesis method. From the initial production of only a small amount to the large-scale production today, it is an excellent progress in chemical synthesis technology. This compound has also emerged in the fields of pharmaceutical research and development, materials science, etc., laying the foundation for many innovative applications. The future development can be expected.

Product Overview

M-Fluoroiodobenzene is an organic compound. It is a colorless to light yellow liquid with a special odor. In this compound, fluorine atoms and iodine atoms are respectively connected to the benzene ring interposition.
In the field of organic synthesis, M-Fluoroiodobenzene has a wide range of uses. Because of its high activity of iodine atoms, it is easy to participate in nucleophilic substitution reactions and can introduce various functional groups. The existence of fluorine atoms gives molecules unique physical and chemical properties, such as enhancing their lipid solubility and affecting their reactivity. It is often used as an intermediate to prepare fine chemicals such as medicines, pesticides, and materials.
The synthesis method is mostly obtained under precise reaction conditions through specific benzene derivatives to be suitable for fluorination and iodization reagents. When preparing, it is necessary to pay attention to factors such as reaction temperature, reagent ratio and reaction time to ensure the purity and yield of the product.

Physical & Chemical Properties

M - Fluoroiodobenzene has its unique physical and chemical properties. Looking at its physical properties, under room temperature, it is in a liquid state, with clear color and pure quality, like a clear spring with slightly rippling waves. Its boiling point is suitable, not high or low, at a certain temperature, quietly vaporized and transformed into invisible.
On its chemical properties, above the benzene ring, fluorine and iodine atoms stand side by side. Fluorine has strong electronegativity and has the effect of absorbing electrons; although iodine has a large atomic radius, it plays an important role in chemical reactions. The synergy between the two makes this compound exhibit different activities in reactions such as nucleophilic substitution and electrophilic substitution. When encountering nucleophilic reagents, iodine atoms are vulnerable to attack and substitution, just like a weak city, vulnerable to foreign invasions. In the field of organic synthesis, it can be used as a key intermediate. After ingenious design, it can be converted into various complex and valuable organic molecules. It is a treasure of chemical synthesis and is of great significance in scientific research and industrial preparation.

Technical Specifications & Labeling

In this study of M-Fluoroiodobenzene, the process specification and identification (product parameters) are the key. Looking at the method of its preparation, precise procedures need to be followed. The material ratio must be appropriate, and the reaction conditions such as temperature and duration need to be strictly controlled. At the beginning of the reaction, all raw materials are put into the reactor in a certain order, and the temperature should gradually rise, and it must not be rushed. After the reaction is completed, the purification technique must also be in compliance to ensure the purity of the product.
On the label, when the name of the product is "M-Fluoroiodobenzene", with the exact molecular formula and molecular weight. Detail the physical and chemical properties, such as appearance, melting point, solubility, etc. Label again warning words, related to toxicity, explosion risk, etc., to warn users to exercise caution and ensure safety.

Preparation Method

The raw materials and production process, reaction steps and catalytic mechanism of this product of M-Fluoroiodobenzene are very important. First, fluorobenzene is taken as the initial raw material, and an iodine substitution reagent is used to react with it. Under the action of a suitable temperature and a specific catalyst, the hydrogen atom of fluorobenzene is replaced by an iodine atom. The reaction steps are first mixed raw materials, heated to the appropriate reaction temperature for the second time, and continuously stirred to promote the reaction. The catalytic mechanism is Wright's specific metal catalyst, which has an active check point to adsorb the reactants, reduce the reaction energy barrier, and accelerate the reaction process. After this series of operations, M-Fluoroiodobenzene products can be obtained. This preparation method can ensure high yield and purity, laying the foundation for its practical application.

Chemical Reactions & Modifications

At the beginning of the reaction, the compatibility of raw materials is established, but the resulting amount is not enough.
Investigate the reason, and the reverse parts may not be good. If the degree of control is not appropriate, the rate of reaction will be low, and the side effect will be low. The same is true. If it is not suitable, it will be difficult to prevent the reverse. Catalysis is also where the activity is not low, and the reverse is low.
Then change it. When the degree of resistance reaches the appropriate range, the value is just right, and it is easier to catalyze and increase its activity. In addition, the degree of, the degree of M-Fluoroiodobenzene rises sharply, and the rate is also high. It can be done well, and it is necessary to reverse the cause, and to do good things, so that you can obtain good things. This transformation is also the way of improvement.

Synonyms & Product Names

Today there is a thing called M-Fluoroiodobenzene. It is unique in the genus of chemistry. Looking for its synonymous name, there are also various expressions.
The ancient books of the study, such substances are often called differently from time to time and from place to place. In the past, or those who were called by different names all referred to the same thing. The names of its commodities have also changed over the years, and various names have been changed.
Although the names are different, their essence is M-Fluoroiodobenzene. This chemical substance is widely used in scientific research. In the process of exploration, scholars trace their origins and delve into their properties according to their synonymous names and commodity names, in order to clarify their functions in chemical, pharmaceutical and other fields, with the hope of opening up new horizons, being used by the world, and benefiting people.

Safety & Operational Standards

The safety and operating standards of M-Fluoroiodobenzene are of paramount importance when studying the products of M-Fluoroiodobenzene today.
This substance has certain characteristics, and when operating, the safety of the environment is the first priority. The laboratory should be well ventilated to prevent the accumulation of harmful gases. The utensils used must be clean and dry to avoid impurities from mixing in, affecting the purity of the product, and preventing accidents.
When taking M-Fluoroiodobenzene, the specifications must be taken according to the exact amount. With a suitable measuring tool, carefully measure the required dose, and the operation should be slow to avoid its splashing. If it is accidentally splashed, clean it immediately according to a specific process. First cover it with an adsorbent material, collect it carefully, and then wash the contaminated area with an appropriate solvent.
During the reaction process, the control of temperature and time is crucial. According to the established reaction conditions, the temperature is precisely regulated to maintain stability with a constant temperature device. The reaction time also needs to be paid close attention, and follow-up operations will be carried out at that time to prevent excessive or insufficient reaction.
Store this product in a cool, dry and ventilated place. Store it in a sealed container to avoid co-storage with oxidizing agents, reducing agents and other easily reactive substances. Labels clearly mark its name, nature, date, etc., for easy access and management.
When experimenters operate, protective equipment is indispensable. Wear experimental clothes, protective gloves and goggles. If volatile operation is involved, you need to wear a gas mask to ensure your own safety. Adhering to these safety and operating standards will ensure the smooth and orderly research and production of M-Fluoroiodobenzene, ensure the safety of personnel, and obtain high-quality products.

Application Area

M-Fluoroiodobenzene is also an organic compound. It is quite useful in the field of chemical synthesis. In medicinal chemistry, it is often a key intermediate for the synthesis of specific drugs. Due to its special structure, it can participate in a variety of chemical reactions to build complex drug molecular structures.
In the field of materials science, it can also be used. It can be introduced into the polymer structure through specific reactions to endow the material with unique electrical and optical properties, such as the preparation of materials with special photoelectric conversion properties.
In addition, it is an important starting material or reaction reagent in organic synthetic chemistry experiments. With its lively chemical properties, it can guide many novel reaction paths, assist chemists in exploring new synthesis strategies, expand the boundaries of organic synthetic chemistry, and demonstrate unique application value in many fields.

Research & Development

Nowadays, there is a chemical thing called M-Fluoroiodobenzene. As a chemical researcher, I have been working hard to explore this thing. Looking at its structure, it contains fluorine and iodine, and its properties are specific. At the beginning, analyzing its composition and understanding its structure is the foundation of research. Then, try different methods to make it. Or take a certain method, the ratio of raw materials, temperature and heat are all carefully observed, but the results are not obvious. Then think about changes, change the method, and after many trials, I gradually get the best path, and the yield is also increased.
And explore its application in the field of medicine, or it can be used as an intermediate to make special drugs; in terms of materials, it also has potential uses, which can give new materials. Although we have achieved something today, there is still a long way to go. We want to further study it and expand its use. We hope to advance in chemistry, which will help to promote the development of this product and add new color to the industry.

Toxicity Research

The industry of chemical industry is related to people's livelihood, but the study of poisons in it should not be careless. Today there is M-Fluoroiodobenzene, and the study of its toxicity is quite important.
M-Fluoroiodobenzene may have chemical activity, but if it enters the body, it will be harmful to the physiological order. The skin touches it, or it may cause redness, swelling, itching and pain; if it enters through breathing, the damage to the lungs and organs cannot be underestimated. And in the environment, there is also the risk of accumulating harm, or sewage or soil, or hurting living beings.
In fact, we should use scientific methods to analyze its structure and explore its sexual changes. Observe its response to other things and observe its transformation in the body. Only by knowing the source of its poison and knowing the path of its harm can we formulate preventive measures and reduce its scourge. Careful research can ensure people's peace and tranquility, and the chemical industry must also be stable.

Future Prospects

In today's world, science and technology are changing day by day. In the field of organic synthesis, M-Fluoroiodobenzene has great hope for future expansion. In the way of pharmaceutical research and development, it can be used as a key intermediate to help create novel and special drugs, cure various difficult diseases, and save people from hardships.
In the journey of material science, new materials with outstanding performance may be derived for use in electronic devices, improve their efficiency, and make operation more agile and efficient; for optical materials, endow unique optical characteristics, and open up new frontiers in optoelectronics.
Although the current production method may be difficult and the cost is high, the road of scientific research is determined to explore. With time, simple and efficient methods will be found to reduce its cost and expand its application. At that time, M-Fluoroiodobenzene will shine like a star, shining brightly on the technological stage of the future, adding luster to human well-being.

Where to Buy M-Fluoroiodobenzene in China?

As a trusted M-Fluoroiodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading M-Fluoroiodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the physical properties of M-fluoroiodobenzene?

M-fluoroiodobenzene is m-fluoroiodobenzene. Its physical properties are as follows:
m-fluoroiodobenzene is usually colorless to light yellow liquid at room temperature and pressure. In this state, it can exhibit unique fluidity and can flow freely in the container. It has a certain density, which is slightly higher than that of water. If it is mixed with water, it will sink to the bottom of the water.
m-fluoroiodobenzene has a specific boiling point. When heated to about 189-190 ° C, it will change from liquid to gaseous state, resulting in boiling phenomenon. This boiling point characteristic makes it possible to realize the conversion of gas-liquid two phases under specific temperature conditions, which is an important application in separation operations such as distillation.
The substance also has a corresponding melting point, which is about -27 ° C. When the temperature drops below the melting point, m-fluoroiodobenzene will condense from liquid to solid, and the molecular arrangement is more orderly and tight when it is solid.
m-fluoroiodobenzene is insoluble in water. Due to the presence of benzene ring and fluorine and iodine atoms in its molecular structure, it has a certain lipid solubility and is more soluble in organic solvents, such as ethanol, ether, dichloromethane, etc., and can be miscible with these organic solvents in any ratio.
In addition, m-fluoroiodobenzene has a certain volatility. In a normal temperature environment, it will slowly evaporate into the air, and it can be smelled to have a special odor. This volatility requires attention to sealing when storing and using it to prevent its volatilization loss and impact on the environment. Its vapor density is higher than that of air, and the vapor will spread close to the ground after volatilization.

What are the chemical properties of M-fluoroiodobenzene?

M-fluoroiodobenzene is also an organic compound. It has unique chemical properties and can be investigated.
First of all, in terms of nucleophilic substitution reactions, due to the atomic characteristics of fluorine and iodine, iodine atoms are easier to leave, resulting in the presence of nucleophilic reagents in this compound. When the nucleophilic reagent exists, the iodine atom site is vulnerable to nucleophilic attack and nucleophilic substitution reaction occurs. This is because its C-I bond energy is relatively low, and it is easier to break than the C-F bond. For example, if hydroxide ions (OH) are used as nucleophilic reagents, they can replace iodine atoms to form products such as m-fluorophenol.
Secondly, in metal-catalyzed reactions, M-fluoroiodobenzene exhi In the coupling reaction catalyzed by palladium, the iodine atom can be coupled with other organic halides or alkenes, alkynes, etc., under the action of appropriate ligands and bases. This is because the palladium catalyst can undergo oxidative addition reaction with the iodine atom, and then realize the construction of carbon-carbon bonds. If Suzuki coupling reaction occurs with vinyl borate, fluorine-containing aryl vinyl compounds can be formed.
Furthermore, its chemical properties are also greatly affected by fluorine atoms. Fluorine atoms have strong electronegativity, which can reduce the electron cloud density of the benzene ring and weaken the activity of the electrophilic substitution reaction of the benzene ring. However, under certain conditions, electrophilic substitution can still occur, and mainly meso-substitution products are formed due to the positioning effect of fluorine atoms.
Because of its fluorine and iodine halogen atoms, in some reactions that require the introduction of halogen atoms, fluorine or iodine atoms can be selectively used to participate in the reaction according to the reaction conditions, providing more strategies and possibilities for organic synthesis.
In short, M-fluoroiodobenzene has rich and diverse chemical properties and has important application value in the field of organic synthesis. It can be used to synthesize various organic compounds through ingenious design of reaction conditions.

What are the main uses of M-fluoroiodobenzene?

M-fluoroiodobenzene, or m-fluoroiodobenzene, has a wide range of main uses. In the field of organic synthesis, m-fluoroiodobenzene is a crucial intermediate. Due to the unique activity of fluorine and iodine atoms in the structure, it can participate in many types of chemical reactions.
First, in the reaction of building carbon-carbon bonds, m-fluoroiodobenzene can react with various boron and tin-containing reagents through coupling reactions such as Suzuki coupling reaction and Stille coupling reaction, and then generate a series of aromatic compounds containing different substituents. Such reactions play a pivotal role in the synthesis of drugs, natural products and materials with specific structures and functions. For example, in the synthesis of some drug molecules, with the help of the coupling reaction involving m-fluoroiodobenzene, specific aryl structures can be precisely introduced to adjust the activity and properties of drug molecules.
Second, m-fluoroiodobenzene also shows important value in the reaction of building carbon-heteroatomic bonds. The reactivity of iodine atoms makes it easy to undergo nucleophilic substitution reactions with nucleophiles containing heteroatoms such as nitrogen, oxygen, and sulfur, thereby generating compounds containing carbon-nitrogen, carbon-oxygen, and carbon-sulfur bonds. These compounds are widely used in the fields of pesticides, dyes, and functional materials. For example, in the creation of some new pesticides, pesticide varieties with high insecticidal or bactericidal activity can be prepared by the reaction of m-fluoroiodobenzene with nitrogen-containing heterocyclic compounds.
Third, due to the large electronegativity and small atomic radius of fluorine atoms, the introduction of fluorine atoms into organic molecules can significantly change the physical and chemical properties of molecules, such as improving the lipophilicity and stability of molecules. Therefore, m-fluoroiodobenzene is an indispensable starting material in the design and synthesis of organic functional materials with special properties, which helps to develop materials with unique optical and electrical properties.

What are the synthesis methods of M-fluoroiodobenzene?

M-fluoroiodobenzene is m-fluoroiodobenzene. There are many ways to synthesize m-fluoroiodobenzene. The common ones are as follows:
First, m-fluoroiodobenzene is used as the starting material, and it is obtained by diazotization and iodine substitution. First, m-fluoroiodobenzene and sodium nitrite undergo diazotization in an acidic environment to form diazonium salts. This diazonium salt is extremely unstable and needs to be reacted immediately with iodine sources such as potassium iodide, and the diazonium group is replaced by iodine atoms to produce m-fluoroiodobenzene. The reaction conditions of this path are relatively mild, the operation is convenient, and the yield is relatively impressive.
Second, m-bromo-fluorobenzene is used as Under the action of metal catalysts such as palladium and nickel, m-bromofluorobenzene reacts with iodizing reagents (such as cuprous iodide, etc.), and the bromine atom is replaced by an iodine atom to achieve the synthesis of m-fluoroiodobenzene. This method has good selectivity, but the catalyst cost is high, and the reaction equipment and operation requirements are also strict.
Third, benzene is used as the starting material and prepared through a multi-step reaction. The benzene is first alkylated by Fu-g, an alkyl group is introduced, and then a halogenation reaction is carried out. Bromine atoms or chlorine atoms are introduced at the meta-position, and then the alkyl group is oxidized to a carboxyl group, and then the carboxyl group is removed by decarboxylation reaction to obtain m-halob This route is complicated and the total yield is low, but the raw materials are cheap and easy to obtain, which has certain advantages in large-scale production.
Each synthetic method has its own advantages and disadvantages. In practical applications, it is necessary to consider the specific needs, such as cost, yield, purity and other factors, and choose the most suitable method.

What should be paid attention to when storing and transporting M-fluoroiodobenzene?

M-fluoroiodobenzene is also an organic compound. When storing and transporting it, many matters need to be paid attention to.
When storing, the first choice of environment. It should be placed in a cool and ventilated warehouse, which is prone to danger due to hot topics and open flames. The temperature of the warehouse should be properly controlled to prevent changes in the properties of the compound caused by excessive temperature. And it is necessary to keep away from fires and heat sources to avoid direct sunlight. The exposure of sunlight may promote chemical reactions and damage the stability of the compound.
Furthermore, the storage place should be isolated from oxidants, acids, bases and other substances. M-fluoroiodobenzene is chemically active, comes into contact with the above substances, or causes violent chemical reactions, such as oxidation, acid-base neutralization, etc., which will not only deteriorate the compound, but also cause serious accidents such as fire and explosion.
When transporting, the packaging must be strong and tight. Appropriate packaging materials must be selected in accordance with regulations to ensure that the packaging is not damaged or leaked during transportation. Transportation vehicles should also be equipped with good ventilation equipment to avoid the accumulation of harmful gases in the vehicle.
Transportation personnel must also be professionally trained to be familiar with the properties of M-fluoroiodobenzene and emergency treatment methods. During transportation, careful loading and unloading should be carried out to prevent collisions and heavy pressure to avoid damage to the packaging. In the event of an accident such as a spill on the way, effective emergency measures must be taken immediately to evacuate personnel and properly handle the spill to ensure the safety of personnel and the environment from pollution. In this way, the safety of M-fluoroiodobenzene storage and transportation can be ensured.