What is the chemical structure of Meta-iodobenzylamine?
Meta-iodobenzylamine, there are also compounds. The analysis can be as follows: With benzene, benzene is a six-membered carbon group, with a special common system, and its characterization. At the meta position of benzene, that is, the position of benzene, there is no iodine atom. Iodine, a group element, has an atomic number of 53, which has a certain degree of stability. There are benzyl amines, benzyl, and benzyl, that is, benzyl, a methyl group (- CH 2O -), this methyl and then an amine group (- NH 2O). The nitrogen atom in the amine group has a solitary child, making it a certain property. In general terms, the transformation of Meta-iodobenzylamine atom is the benzyl position of the iodine atom, which makes it have special physical and chemical properties, and may have important uses in the fields of synthesis, physicochemistry, etc. Its chemical formula can be used as C-H-IN, and the molecular weight can be calculated to obtain the molecular weight of its phase. The atomic weight of carbon (C) is 12, the atomic weight of (H) is 1, the atomic weight of iodine (I) is 127, and the atomic weight of nitrogen (N) is 14. The molecular weight can be obtained by calculating. The properties of this compound are affected by its effects, such as the existence of iodine atoms, which can be reversed by the generation of hydrogen, amine groups can be reacted by acylation, alkylation, etc., and benzene can be replaced by benzene.
What are the main uses of Meta-iodobenzylamine?
Meta-iodobenzylamine, Chinese name meta-iodobenzylamine, is an organic compound, which is widely used in medicine, materials and other fields.
In the field of medicine, it is mainly used for the preparation of radiopharmaceuticals. Radionuclide-labeled meta-iodobenzylamine can be used as an imaging agent for tumor diagnosis. Such as neuroendocrine tumors, such tumor cells have a strong ability to uptake meta-iodobenzylamine. After labeling, imaging technology can clearly show the location, size and shape of the tumor, helping doctors to accurately diagnose and treat. At the same time, it is also of great significance for the diagnosis of cardiovascular system diseases, which can help evaluate cardiac sympathetic function and provide key information for the diagnosis and treatment of related diseases.
In the field of materials, m-iodobenzylamine can be used as an intermediate in organic synthesis and participates in the synthesis of many organic materials. Due to its structure containing iodine and amino groups, it has unique reactivity, and can introduce other functional groups through chemical reactions to synthesize materials with special properties. For example, it is used in the synthesis of optoelectronic materials. The materials are used in optoelectronic devices, or have excellent photoelectric conversion properties, providing new material options for the development of optoelectronic devices.
In addition, in the field of scientific research, m-iodobenzylamine is often used as a model compound for chemical research. By studying its reaction mechanism and chemical properties, researchers can deeply understand the laws of organic chemical reactions, provide theoretical basis and practical experience for the development of organic synthetic chemistry, and promote the progress of organic chemistry
What are the physical properties of Meta-iodobenzylamine?
Meta-iodobenzylamine, the Chinese name for iodobenzylamine, is also an organic compound. Its physical properties are particularly important, and I will describe them in detail today.
Looking at its properties, under normal circumstances, meta-iodobenzylamine is mostly colorless to light yellow liquid, which is easy to observe. It has a certain volatility, in the air, or can gradually dissipate, and this characteristic is also not negligible.
When it comes to melting point, there is no exact record of its exact value in ancient books, but according to today's usual practice, the melting point of such compounds may be low due to their molecular structure and interaction forces.
The boiling point is within a certain range, roughly around [X] ° C (slightly different due to actual conditions). This boiling point value is the key temperature for a substance to change from liquid to gaseous state, and it is related to its distillation, separation and other operations.
In terms of solubility, meta-iodobenzylamine is partially soluble in water, but more soluble in many organic solvents, such as ethanol and ether. This difference in solubility is due to the fact that its molecules have both polar and non-polar parts, and interact with water and organic solvents differently.
Density is also one of the important physical properties. Its density is about [X] g/cm ³, which is slightly heavier or lighter than water. This property has a significant impact on experimental phenomena such as mixing and stratification.
In addition, meta-iodobenzylamine may have a certain odor or an irritating odor. This odor characteristic can also be used as a reference for identification. However, caution should be used when smelling, because it may have certain irritation hazards to the human respiratory tract.
What are Meta-iodobenzylamine synthesis methods?
Meta-iodobenzylamine (m-iodobenzylamine) is an important intermediate in organic synthesis, and its synthesis methods are various. Details are as follows:
The starting material is m-iodobenzoic acid. First, m-iodobenzoic acid is co-heated with thionyl chloride ($SOCl_2 $), and this reaction produces m-iodobenzoyl chloride. In this process, thionyl chloride acts as a chlorination agent, which can convert carboxyl groups into acyl chlorides. The reaction is as follows: $m-iodobenzoic acid + SOCl_2\ stackrel {\ Delta} {\ longrightarrow} m-iodobenzoyl chloride + SO_2\ uparrow + HCl\ uparrow $.
After obtaining m-iodobenzoyl chloride, it reacts with ammonia ($NH_3 $) to form m-iodobenzamide. This reaction is nucleophilic substitution. The nitrogen atom in the ammonia molecule attacks the carbonyl chloride, and the chlorine atom leaves. The reaction formula is: $m-iodobenzoyl chloride + NH_3\ longrightarrow m-iodobenzamide + HCl $.
Subsequently, m-iodobenzamide can be obtained by reducing m-iodobenzamide with lithium aluminum hydride ($LiAlH_4 $). Lithium aluminum hydride is a strong reducing agent that can reduce amide groups to amino groups. The reaction formula is: $m-iodobenzamide + LiAlH_4\ stackrel {appropriate solvent} {\ longrightarrow} m-iodobenzylamine $. Careful hydrolysis is required after the reaction to remove excess reducing agents and by-products such as aluminum salts.
Another method is to use m-iodotoluene as a starting material. First, m-iodotoluene is reacted with $N-bromosuccinimide (NBS) $in carbon tetrachloride ($CCl_4 $) solution in the presence of an initiator such as benzoyl peroxide (BPO). Bromine atoms can be introduced at the benzyl position to obtain m-iodobenzyl bromide. This is a free radical substitution reaction. The reaction formula is: $m-iodotoluene + NBS\ stackrel {BPO, CCl_4,\ Delta} {\ longrightarrow} m-iodobenzyl bromide + succinimide $.
Then m-iodobenzyl bromide is reacted with excess ammonia water, and ammonia molecules nucleophilically replace bromine atoms to generate m-iodobenzyl amine. This reaction requires attention to control the reaction conditions, such as temperature, ammonia concentration and reaction time, to ensure the yield and purity. The reaction formula is: $m-iodobenzyl bromide + excess NH_3\ longrightarrow m-iodobenzyl amine + NH_4Br $.
The above synthetic routes have their own advantages and disadvantages, and the practical application needs to be comprehensively considered and selected according to the availability of raw materials, cost, reaction conditions and product purity requirements.
Meta-iodobenzylamine what are the precautions during use
Meta-iodobenzylamine is also a chemical substance. When using it, it is important to pay attention to things like this.
The first one, its chemical properties are also. This substance has a specific chemical activity, and it is afraid of severe reactions when mixed with other substances or in case of special substances. Therefore, before using it, it is necessary to know its chemical properties and be familiar with its possible anti-chemical types in order to avoid danger.
For the second time, it is necessary to be safe and protected. This substance may be toxic, corrosive, or sensitizing. The user uses anti-protective equipment, such as gas masks, anti-eye masks, anti-chemical gloves, and anti-wear, to protect themselves. In operation, it is also necessary to be good, and if necessary, it should be placed in suction and drainage to avoid harmful accumulation.
Furthermore, the method of storage should not be ignored. It should be placed in a dry, dry and transparent place, away from direct light, away from fire sources, sources and active substances such as oxidizers and raw materials. Store in dense containers to prevent leakage.
In addition, use the process to refine. According to the requirements of the machine or the work, measure with the equipment of the machine, and the operation method is cooked. Use the machine to properly manage the remaining materials, according to the phase, do not pour them out, so as not to stain the environment.
Therefore, the use of meta-iodobenzylamine requires careful attention to chemical properties, prevention, storage, and operation, so as to use this product safely and effectively to avoid accidents.