N 2 3 Dihydroxypropoxy 3 4 Difluoro 2 2 Fluoro 4 Iodophenyl Amino Benzamide
Iodobenzene

N 2 3 Dihydroxypropoxy 3 4 Difluoro 2 2 Fluoro 4 Iodophenyl Amino Benzamide

Fengxi Chemical

Specifications

HS Code

390414

Chemical Formula C16H14F3IN2O4
Molecular Weight 482.196
Packing & Storage
Packing 10 - gram vial of N-(2,3 - dihydroxypropoxy)-3,4 - difluoro - 2 - [(2 - fluoro - 4 - iodophenyl)amino]benzamide, well - sealed.
Storage Store “N-(2,3 - dihydroxypropoxy)-3,4 - difluoro - 2 - [(2 - fluoro - 4 - iodophenyl)amino]benzamide” in a cool, dry place away from direct sunlight. Keep it in a tightly - sealed container to prevent moisture absorption and exposure to air, which could potentially lead to degradation. Store away from incompatible substances to avoid chemical reactions.
Shipping The chemical "N-(2,3 - dihydroxypropoxy)-3,4 - difluoro - 2 - [(2 - fluoro - 4 - iodophenyl)amino]benzamide" will be shipped in well - sealed, corrosion - resistant containers, following all relevant chemical transport regulations to ensure safety during transit.
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N-(2,3-dihydroxypropoxy)-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide N-(2,3-dihydroxypropoxy)-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide N-(2,3-dihydroxypropoxy)-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide
General Information
Frequently Asked Questions
What is the chemical structure of N- (2,3-dihydroxypropoxy) -3,4-difluoro-2- [ (2-fluoro-4-iodophenyl) amino] benzamide?
The name of this organic compound is extremely complicated, and the analysis of its chemical structure according to its name is like a delicate mechanism for disassembling, and it is necessary to be careful step by step.
"N- (2,3-difluorobenzoxy) -3,4-dichloro-2- [ (2-chloro-4-thiophenyl) amino] thiophenoformamide". From the beginning of the name, "N -" indicates that the substituent is attached to the nitrogen atom. " (2,3-difluorobenzoxy) ", this is a benzoxy group with fluorine atoms substituted at the 2nd and 3rd positions of the benzene ring, just like adding fluorine "leaves" at specific positions of the "branches" of the benzoxy group.
"3,4-dichloro-2- [ (2-chloro-4-thiophenyl) amino] thiophene formamide", the core is thiophene formamide structure. The 3rd and 4th positions of the thiophene ring are occupied by chlorine atoms, and the 2nd position is connected to a nitrogen-containing group, which in turn is connected to (2-chloro-4-thiophenyl), that is, the 2nd position of the thiophene ring has a chlorine atom, and the 4th position is connected to the above nitrogen atom.
In the structure of this compound, multiple substituents are cleverly spliced on the core structure of thiophenylformamide, and the position and type of each substituent determine its unique chemical properties and spatial configuration. Its structure is constructed like a delicate castle built by skilled craftsmen in ancient times, each part has its specific position and function, which affects the whole body. The atoms and groups interact to give this compound specific physical and chemical properties.
What are the main uses of N- (2,3-dihydroxypropoxy) -3,4-difluoro-2- [ (2-fluoro-4-iodophenyl) amino] benzamide?
N- (2,3-difluorobenzoxy) -3,4-dichloro-2- [ (2-chloro-4-cyanobenzyl) amino] benzonitrile, this compound has very important uses in chemical and related fields.
First, in the field of pesticides, it can be used as a key active ingredient to create new pesticides. With its unique chemical structure, it shows efficient poisoning ability to specific pests. The nervous system or physiological and metabolic processes of some pests will be disturbed by it, thus effectively inhibiting the growth and reproduction of pests, achieving precise prevention and control of crop pests, and escorting agricultural harvests.
Second, in the field of pharmaceutical research and development, the structural characteristics of this compound provide the possibility for the exploration of new drugs. Scientists can modify and optimize its structure to find lead compounds with specific pharmacological activities. For example, it may exhibit good binding ability for specific targets related to certain diseases, thus laying the foundation for the development of innovative drugs to treat the disease.
Third, in the field of materials science, its special structure may endow materials with some novel properties. For example, the introduction of this structural unit in polymer materials is expected to change the electrical, optical or thermal properties of materials, so as to prepare new materials with special functions to meet the special needs of electronics, optics and other fields.
What is the synthesis method of N- (2,3-dihydroxypropoxy) -3,4-difluoro-2- [ (2-fluoro-4-iodophenyl) amino] benzamide?
To prepare N- (2,3-difluorobenzoxy) -3,4-dichloro-2- [ (2-chloro-4-pyridyl) amino] benzamide, the following ancient method can be carried out:
First take the appropriate starting material, take 2,3-difluorobenzyl alcohol as one of them, and place it in the reaction kettle with a suitable halogenating agent, such as thionyl chloride, and add moderate temperature, accompanied by stirring. In this process, the alcohol hydroxyl group will be replaced by the halogen atom to generate 2,3-difluorobenzyl halide. The key to the reaction lies in the precise control of the temperature. If it is too high, there will be many side reactions, and if it is too low, the reaction will be slow. At the same time, 3,4-dichlorobenzoyl chloride can be prepared by co-heating 3,4-dichlorobenzoic acid with thionyl chloride. This acid chloride has high activity and is a key intermediate for subsequent reactions.
Then, 2-chloro-4-aminopyridine is added into an appropriate amount of solvent, such as dichloromethane or N, N-dimethylformamide, and then slowly added to the obtained 3,4-dichlorobenzoyl chloride. This reaction needs to be carried out in a weak base environment, and an appropriate amount of triethylamine or pyridine can be added to bind the acid and promote the reaction. At this stage, the nucleophilic substitution reaction between the amino group and the acyl chloride will occur, resulting in 3,4-dichloro-2-[ (2-chloro-4-pyridyl) amino] benzoyl chloride.
Finally, the previously prepared 2,3-difluorobenzyl halide is mixed with 3,4-dichloro-2-[ (2-chloro-4-pyridyl) amino] benzoyl chloride, and the reaction is heated in a suitable organic solvent in an alkaline environment, such as in the presence of an aqueous solution of potassium carbonate or sodium carbonate. The halogen atom of benzyl halide is connected to the oxygen atom of the carbonyl α-position of benzoyl chloride. After nucleophilic substitution, the final target product is N- (2,3-difluorobenzyloxy) -3,4-dichloro-2 - [ (2-chloro-4-pyridyl) amino] benzamide. After the reaction is completed, the pure product can be obtained by extraction, washing, drying, column chromatography and other separation and purification methods.
Throughout the synthesis process, each step of the reaction needs to be carefully controlled by the reaction conditions. The proportion of raw materials, temperature, pH and other factors have a huge impact on the yield and purity of the product, so it is necessary to be cautious.
What are the safety and toxicity of N- (2,3-dihydroxypropoxy) -3,4-difluoro-2- [ (2-fluoro-4-iodophenyl) amino] benzamide?
This substance is called N- (2,3-difluorobenzoxy) -3,4-dichloro-2-[ (2-chloro-4-cyanophenyl) amino] benzamide, which is a common chemical in the field of organic synthesis.
Its safety and toxicity need to be carefully studied. From a chemical structure point of view, this molecule contains fluorine, chlorine and other halogen atoms, as well as cyano and other specific functional groups. The presence of halogen atoms may make the substance chemically active, under certain conditions, or participate in chemical reactions to form new compounds. Cyanyl is a highly toxic functional group. Once the substance degrades in the environment, if the cyanyl group is released, it may pose a serious hazard to organisms and the environment.
In terms of safety, strict protective measures must be taken when producing, storing and using this substance. When operating, operators should wear professional protective equipment, such as protective clothing, gloves and gas masks, to prevent skin contact and inhalation. Storage should be placed in a cool, dry and well-ventilated place, away from sources of ignition and oxidants, to avoid accidents such as fire or explosion.
In terms of its toxicity, experiments and related studies have shown that compounds containing cyanyl groups are usually toxic to organisms. It may interfere with the enzyme activity and cellular respiration process in the organism, and then affect the normal physiological function of the organism. If accidentally ingested, inhaled or absorbed through the skin, or cause damage to the human nervous system, cardiovascular system, etc., even life-threatening.
In short, for N- (2,3-difluorobenzoxy) -3,4-dichloro-2- [ (2-chloro-4-cyanophenyl) amino] benzamide, it is necessary to fully recognize its latent risk, and strictly follow safety regulations in all links to ensure the safety of personnel and the environment.
What is the price range for N- (2,3-dihydroxypropoxy) -3,4-difluoro-2- [ (2-fluoro-4-iodophenyl) amino] benzamide in the market?
The name of this compound is lengthy and complicated, and the market price range of the substance will fluctuate due to various factors, such as production process, purity, market supply and demand, etc. However, due to the lack of more specific information, it is difficult to accurately determine its price range.
In ancient times, the price is often based on the thinness of the substance, the wide range of use, and the difficulty of making it. If the preparation of this substance is difficult, the raw materials are rare, the process is complicated, and it is widely used in important fields such as medicine and chemical industry, the price may be high; if the preparation is easy, the raw materials are common, and the demand is limited, the price may be close to the people.
However, only according to the given name, it is difficult to understand the difficulty of production and the market supply and demand. In order to know the market price range, we should carefully study the chemical raw materials market report, consult industry experts, or check the recent quotations of the chemical products trading platform to obtain a relatively accurate price range.