This product What is the chemical structure of N- [3- [3-cyclopropyl-5- [ (2-fluoro-4-iodophenyl) amino] -3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxo pyrimido [4,3-d] pyrimidine-1 (2H) -yl] phenyl] acetamide?

This is an extremely complex naming of organic compounds. To clarify their chemical structure, it is necessary to follow the rules of organic chemistry. However, according to the name "N- [3- [3-cyclopropyl-5- [ (2-tritium-4-chlorophenyl) amino] -3,4,6,7-tetrahydro-6,8-diethyl-2,4,7-trioxo pyrimido [4,3-d] pyrimidine-1 (2H) -yl] phenyl] acetamide", its structure is deduced from the quaint literary style of "Tiangong Kaiwu" as follows:

Looking at the name, it is known that this compound contains multiple key structural units. "Acetamide" is the basic framework, with a specific phenyl group attached at one end. On this phenyl group, the side chain has a complex structure at the 3rd position. The side chain contains cyclopropyl at the 3rd position; the 5th position has a part connected by 2-tritium-4-chlorophenyl through amino groups. It also contains the structure of pyridino [4,3-d] pyrimidine, in which 3,4,6,7-tetrahydro, 6,8-diethyl, 2,4,7-trioxo, 1 (2H) -yl is connected to phenyl.

can be roughly outlined, acetamide's nitrogen-linked phenyl group, phenyl group are connected to the complex side chain in sequence, and the groups in the side chain are arranged in sequence, with cyclopropyl group, tritium-containing and chlorine-containing phenyl group in their respective positions, and the structure of pyridyl-pyrimidine is also modified and integrated. In this way, although it cannot be shown in a precise diagram, according to this simple text analysis, a preliminary and macroscopic understanding of the chemical structure of the compound can be obtained.

What are the main uses of N- [3- [3-cyclopropyl-5- [ (2-fluoro-4-iodophenyl) amino] -3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxo pyridino [4,3-d] pyrimidine-1 (2H) -yl] phenyl] acetamide?

This is a rather complex organic compound called N- [3- [3-cyclopropyl-5- [ (2-ene-4-thiophenyl) ethylamino] -3,4,6,7-tetranitrogen-6,8-diethyl-2,4,7-trioxo-pyridino [4,3-d] pyrimidine-1 (2H) -yl] thiophenyl] acetamide. It has a wide range of uses in the field of medicine and is often used as a pharmaceutical active ingredient to assist in the treatment and prevention of diseases. For example, in the research and development of anti-cancer drugs, its unique chemical structure may precisely act on specific targets of cancer cells, interfering with the growth, proliferation and metastasis of cancer cells, and bringing new hope for cancer treatment. In terms of antibacterial drugs, it may destroy bacterial cell wall synthesis, interfere with bacterial metabolic processes, effectively inhibit bacterial growth and reproduction, and treat bacterial infectious diseases. In the agricultural field, it may be developed as a new type of pesticide, which has the effect of repelling, inhibiting growth or poisoning pests, protecting crops from pests and diseases, improving crop yield and quality, and being environmentally friendly and reducing traditional pesticide pollution. It can also provide key intermediates for chemical synthesis, which can be used to prepare polymer materials and fine chemicals with unique properties, and promote the innovation and development of the chemical industry.

What are the synthesis methods of N- [3- [3-cyclopropyl-5- [ (2-fluoro-4-iodophenyl) amino] -3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxo pyridino [4,3-d] pyrimidine-1 (2H) -yl] phenyl] acetamide?

The synthesis method of this compound is complicated, and it is not enough to describe it in a few words. Ran Wu will follow the ancient meaning of "Tiangong Kaiwu" and roughly state it.

To prepare N - [3 - cyclopropyl - 5 - [ (2 - enyl - 4 - cyanobenzyl) amino] - 3,4,6,7 - tetrahydro - 6,8 - diethyl - 2,4,7 - trioxyquinolino [4,3 - d] pyrimidine - 1 (2H) - yl] benzyl] acetamide, a suitable starting material should be selected first. Cyclopropyl-related compounds, benzyl derivatives containing alkenyl and cyanyl groups, quinolinopyrimidine substrates with diethyl and tetrahydro structures, etc., are all key initiators.

In the reaction step, the nucleophilic substitution reaction of the amino-containing structure with suitable halogenates or active esters is first carried out to introduce specific substituents. This process requires attention to the reaction conditions, such as temperature, solvent, type and dosage of base. Too high or too low temperature may cause abnormal reaction rates and affect the yield and purity of the product.

Subsequently, cyclization is carried out to construct the core structure of quinolinopyrimidine. This step may require the help of specific catalysts, such as metal catalysts or Lewis acids, to promote intramolecular cyclization. At the same time, the pH and reaction time of the reaction system should be regulated to ensure the smooth progress of the cyclization reaction and avoid the occurrence of side reactions, such as excessive cyclization or isomerization.

In addition, for functional groups such as alkenyl groups and cyanyl groups, further conversions can be carried out according to needs. Alkenyl groups can be modified by addition, oxidation, etc.; cyanyl groups can be hydrolyzed into carboxyl groups, or converted into amino groups by reduction reactions to meet the structural requirements of the final product.

After each step of the reaction is completed, the separation and purification of the product is also crucial. Commonly used methods include column chromatography, recrystallization, etc. Column chromatography can be separated according to the polarity difference of the compound; recrystallization can be purified by the different solubility of the compound in different solvents. Through strict control of each link, the target product can be obtained.

What are the physical and chemical properties of N- [3- [3-cyclopropyl-5- [ (2-fluoro-4-iodophenyl) amino] -3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxo pyridino [4,3-d] pyrimidine-1 (2H) -yl] phenyl] acetamide?

This is a complex organic compound called N- [3- [3-cyclopropyl-5- [ (2-ene-4-cyanobenzyl) amino] -3,4,6,7-tetranitrogen-6,8-diethyl-2,4,7-trioxo-pterido [4,3-d] pyrimidine-1 (2H) -yl] benzyl] acetamide. It has many unique physical and chemical properties.

From the perspective of physical properties, this compound is mostly solid at room temperature, and its molecular structure is arranged in an orderly manner due to strong intermolecular forces. Its melting point is influenced by intermolecular forces and crystal structures, or is in a higher temperature range, requiring specific energy to break the lattice binding and cause phase transition.

In terms of solubility, due to the presence of polar and non-polar groups, it has good solubility in organic solvents, such as dichloromethane, chloroform, etc. Polar groups interact with organic solvents in polarity, and non-polar groups are partially miscible with organic solvents. However, its solubility in water may be limited, because its overall molecular structure is not highly hydrophilic, and only some polar groups interact weakly with water.

Chemically, the cyanide group in this compound has high reactivity and can participate in nucleophilic addition, hydrolysis and other reactions. The amino group can be used as a nucleophilic reagent to react with electrophilic reagents, such as acylation and alkylation reactions. Cyclopropyl has high ring tension and is easy to open rings. It participates in various ring-opening addition reactions and expands molecular structures. The structure of trioxo-pteridine pyrimidine also contains reactive activity check points. Under specific conditions, it participates in oxidation, reduction or cyclization reactions to transform molecular configurations and properties.

This compound has important application value in organic synthesis and medicinal chemistry due to its diverse physical and chemical properties. It can be used as an intermediate to synthesize more complex functional molecules, or to develop specific biologically active drugs for lead compounds.

What are the market prospects for N- [3- [3-cyclopropyl-5- [ (2-fluoro-4-iodophenyl) amino] -3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxo pyridino [4,3-d] pyrimidine-1 (2H) -yl] phenyl] acetamide?

This compound, named N- [3- [3-cyclopropyl-5- [ (2-ene-4-thiophenyl) amino] -3,4,6,7-tetrahydro-6,8-diethyl-2,4,7-trioxo pyridino [4,3-d] pyrimidine-1 (2H) -yl] thiophenyl] acetamide, its market prospect remains to be studied.

This substance is in the field of pharmaceutical and chemical industry, and there may be potential opportunities. The structures of cyclopropyl and thiophenyl give it unique properties. However, the road ahead for the market is still multi-terminal.

First look at the research and development of medicine, or because of the unique structure, it can involve the creation of new drugs. For specific targets, or with the ability of affinity and regulation, it will add a boost to the development of new anti-disease drugs. However, the research and development of new drugs is full of dangers, from mechanism exploration to clinical trials, there are many obstacles, and the road to finished drugs is long.

Chemical production is also a consideration. If the synthesis process is complicated, the cost will be high, and marketing activities will be hindered. To expand the market, optimize the process, reduce costs and increase efficiency is a top priority. And environmental protection regulations are becoming stricter, and waste treatment in the production process is also the key.

Re-examine the market competition. Compounds of the same type or similar structure may have taken the lead. To stand out, it is necessary to show unique advantages, such as better curative effect and fewer side effects.

In summary, N- [3- [3-cyclopropyl-5- [ (2-enyl-4-thiophenyl) amino] -3,4,6,7-tetrahydro-6,8-diethyl-2,4,7-trioxo-pyridino [4,3-d] pyrimidine-1 (2H) -yl] thiophenyl] acetamide market prospects, opportunities and challenges coexist. Only in R & D, production and market aspects, intensive cultivation can we gain a place in the market.