As a leading N-[3-[3-Cyclopropyl-5-[(2-Fluoro-4-Iodophenyl)Amino]-3,4,6,7-Tetrahydro-6,8-Dimethyl-2,4,7-Trioxopyrido[4,3-D]Pyrimidin- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of N- [3- [3-cyclopropyl-5- [ (2-fluoro-4-iodophenyl) amino] -3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido [4,3-d] pyrimidin-
The full name of this compound is N- [3- [3-cyclopropyl-5- [ (2-fluoro-4-iodophenyl) amino] -3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxo pyrimido [4,3-d] pyrimidine-1 (2H) -yl] propyl] acetamide, and its structure is relatively complex and can be gradually resolved.
Pyridino [4,3-d] pyrimidine is used as the core mother ring, which is connected to a side chain containing cyclopropyl group at the 3rd position, and is connected to the (2-fluoro-4-iodophenyl) amino group at the 5th position. The mother ring is tetrahydrogenated at the 3,4,6,7 positions, with methyl substitution at the 6,8 positions, and carbonyl oxygen at the 2,4,7 positions. The mother ring 1 (2H) is connected to the acetamido group through propyl. In the classical Chinese format of "Tiangong Kaiwu", it can be described as:
The structure of this chemistry, the core, the ring of pyridino [4,3-d] pyrimidine. The 3-position side chain is attached to the cyclopropyl group, and the 5-position is associated with the (2-fluoro-4-iodophenyl) amino group. The 3, 4, 6, and 7 positions between the rings are in the state of tetrahydro, the 6 and 8 positions have methyl groups, and the 2, 4, and 7 positions are occupied by carbonyl oxygen. The 1 position (2H) is connected to the acetamide group through the propyl group, and the structure is exquisite and the combination is complicated. This is the wonder of chemistry.
What are the physical properties of N- [3- [3-cyclopropyl-5- [ (2-fluoro-4-iodophenyl) amino] -3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido [4,3-d] pyrimidin
N - [3- [3-cyclopropyl-5- [ (2-fluoro-4-iodophenyl) amino] - 3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxo-pyrimido [4,3-d] pyrimidine - This compound has some unique physical properties. Its appearance or specific crystalline form, due to the arrangement and interaction of various atoms in the molecular structure, the crystal has a specific lattice structure and crystal form.
In terms of melting point, due to the existence of different strengths of forces between molecules, such as hydrogen bonds, van der Waals forces, etc., the compound will have a specific melting point range, which is affected by the stability and compactness of the molecular structure. In terms of solubility, it dissolves differently in different solvents due to the polar groups and non-polar parts contained in the molecule. Containing polar groups makes it soluble in polar solvents such as water and alcohols; while non-polar parts make it soluble in non-polar solvents such as alkanes to varying degrees.
The density of the compound is also affected by the molecular structure and accumulation mode, and the relative mass of its molecules and the volume of its occupied space together determine the density value. In addition, its refractive index is related to the refractive properties of the molecule to light, and the distribution of electron clouds and chemical bond properties in the molecule will affect the propagation and refraction of light, resulting in a specific refractive index. These physical properties are interrelated and determined by its unique molecular structure, which is of great significance in chemical research and practical applications.
What is the synthesis method of N- [3- [3-cyclopropyl-5- [ (2-fluoro-4-iodophenyl) amino] -3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido [4,3-d] pyrimidin-
Synthesis of N- [3- [3-cyclopropyl-5- [ (2-fluoro-4-iodophenyl) amino] -3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxo pyrimido [4,3-d] pyrimidine-1 (2H) -yl] propyl] acetamide is a delicate investigation in the field of organic synthesis.
The choice of starting materials is crucial. When based on a pyrimidine derivative with a specific structure, the derivative needs to contain modifiable check points, such as cyclopropyl, amino groups, etc., in order to lay the foundation for subsequent reactions. To obtain this derivative, suitable pyrimidine and pyrimidine compounds are often synthesized by condensation. During condensation, the reaction conditions, such as temperature, pH, and catalyst dosage, need to be carefully regulated. If the temperature is too high, or side reactions may occur; if the temperature is too low, the reaction will be slow and the efficiency will be poor. The accurate grasp of pH is also related to the reaction process and product purity.
For the introduction of the key [ (2-fluoro-4-iodophenyl) amino] fragment, nucleophilic substitution is often used. With the activity check point of 2-fluoro-4-iodoaniline and pyrimidine derivatives, the reaction is orderly under the action of suitable solvents and bases. The nature of the solvent has a great influence on the reaction rate and selectivity. Polar solvents may accelerate the reaction, but they may also exacerbate the side reactions; although non-polar solvents can reduce side reactions, they may slow down the reaction rate. The strength and dosage of bases also need to be carefully considered. If it is strong, it may lead to the decomposition of the substrate, and if it is weak, the reaction will be difficult to continue.
The connection of the propyl chain is often achieved by alkylation reaction. The halogenated hydrocarbon or sulfonate containing propyl group is reacted with the active group on the pyridyl pyrimidine derivative in a suitable reaction system with the help of a phase transfer catalyst. The phase transfer catalyst can promote the mass transfer of the reactants between different phases and improve the reaction efficiency. However, the optimization of its type and dosage is also the key. Too much or increase the cost, and too little catalytic effect is not good.
When the key fragments are all connected, the purification and refining of the final product are indispensable. Recrystallization, column chromatography and other methods are commonly used to remove impurities and extract product purity. During recrystallization, the selection of solvent and the control of crystallization conditions determine the crystal form and purity of the product. Column chromatography requires the rational selection of fixed phase and mobile phase according to the polarity difference between the product and the impurity to achieve the purpose of effective separation.
N- [3- [3-cyclopropyl-5- [ (2-fluoro-4-iodophenyl) amino] -3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido [4,3-d] pyrimidin - In which fields is it used?
N - [3 - [3 - cyclopropyl - 5 - [ (2 - fluoro - 4 - iodophenyl) amino] - 3,4,6,7 - tetrahydro - 6,8 - dimethyl - 2,4,7 - trioxo pyridino [4,3 - d] pyrimidine - such compounds are used in medicine and may have the potential to cure diseases and save people. Looking at the field of current medicine, it may be used to develop a good medicine against difficult diseases. In the path of pharmaceutical exploration, researchers often search for molecules with such unique structures to investigate their impact on human physiology, explore their role in the treatment of diseases, and hope to find ways for patients to recover.
In the field of chemical research, such complex compounds pose challenges and opportunities for organic synthesis. Chemists need to use exquisite skills to construct their unique structures in precise steps, deeply analyze their chemical properties, and pave the way for subsequent applications. In the long journey of new drug development, this compound may be a key cornerstone, helping to develop new therapeutic methods and drug categories, adding new hope for human health and well-being.
What is the market outlook for N- [3- [3-cyclopropyl-5- [ (2-fluoro-4-iodophenyl) amino] -3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido [4,3-d] pyrimidin-
I don't know what you mean by "N - [3 - [3 - cyclopropyl - 5 - [ (2 - fluoro - 4 - iodophenyl) amino] - 3,4,6,7 - tetrahydro - 6,8 - dimethyl - 2,4,7 - trioxopyrido [4,3 - d] pyrimidin -", this is a very unfamiliar chemical description. However, if you look at the prospects of this substance in the market, you should consider it from many aspects.
The first one to bear the brunt is its use. If this substance can be used in the field of medicine, can cure difficult and miscellaneous diseases, or has special effects on common diseases, there must be a broad market. Like an elixir, doctors want to use it to cure diseases and save people, and patients also hope that it will relieve their pain, so the market demand will be great. If it is used in the chemical industry, it can be used as a key raw material to create novel and practical products that meet people's daily needs or industrial requirements, and can also occupy a place in the market.
Furthermore, it is necessary to consider the difficulty and cost of its research and development. If the research and development of this substance is as difficult as reaching the sky, it will cost a lot of manpower, material resources and financial resources, resulting in high costs. Even if the effect is significant, marketing activities will be hindered. Just like creating a rare treasure, the cost is too high, and few people can buy it. However, if the research and development method is gradually simpler and the cost is controllable, it will be easier for the market to accept.
It is also necessary to observe the competitive situation. If this substance is unique and there is no similar substitute, it is like the only remaining treasure in the world, and its market has the voice over it. But if there are many products with similar functions on the market, the competition will be as fierce as a battlefield, and it needs to be won with unique advantages, or the effect is better, or the price is more close to the people.
And market policies and regulations also have far-reaching implications. If relevant policies encourage the development and production of such substances, they will support it, just like sailing a boat with the wind, and the future will be bright. On the contrary, if it is restricted by strict regulations and many procedures are cumbersome, its development may be hindered.
To sum up, the market prospects of this substance cannot be determined lightly. It is necessary to comprehensively consider various factors such as use, cost, competition and policy in order to know its rise and fall in the market.
![N-[3-[3-Cyclopropyl-5-[(2-Fluoro-4-Iodophenyl)Amino]-3,4,6,7-Tetrahydro-6,8-Dimethyl-2,4,7-Trioxopyrido[4,3-D]Pyrimidin-](https://alchemist-1317689233.cos.ap-nanjing.myqcloud.com/a5b4c857-d896-4a64-9dbc-f3b40103b7d4/images/product_inner2.jpg)
