N-{3-Chloro-4-[(3-Fluorobenzyl)Oxy]Phenyl}-6-Iodo-4-Quinazolinamine

Fengxi Chemical

Specifications

HS Code	599796
Chemical Formula	C22H16ClFIN3O
Molecular Weight	533.74
Appearance	Solid (predicted)
Boiling Point	621.6±65.0 °C at 760 mmHg (predicted)
Melting Point	173 - 175 °C
Density	1.64±0.1 g/cm3 (predicted)
Logp	6.34 (predicted)
Pka	13.41±0.70 (predicted)
Refractive Index	1.703 (predicted)

As an accredited N-{3-Chloro-4-[(3-Fluorobenzyl)Oxy]Phenyl}-6-Iodo-4-Quinazolinamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	10 - gram vial of N - {3 - chloro - 4 - [(3 - fluorobenzyl)oxy]phenyl}-6 - iodo - 4 - quinazolinamine, well - sealed.
Storage	Store "N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-iodo-4-quinazolinamine" in a cool, dry place, away from heat sources and direct sunlight. Keep it in a tightly sealed container to prevent moisture absorption and potential reaction with air components. Store separately from incompatible substances to avoid chemical reactions.
Shipping	The chemical "N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-iodo-4 -quinazolinamine" will be shipped in specialized, sealed containers. Strict safety protocols are followed to ensure secure transit, compliant with chemical shipping regulations.

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N-{3-Chloro-4-[(3-Fluorobenzyl)Oxy]Phenyl}-6-Iodo-4-Quinazolinamine

General Information

Historical Development

I am engaged in the research of chemical products. Recently, my focus is N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide. The beginning of this product originated from the research several years ago. At that time, we went through the classics, and we were poor in the delicacy of chemistry, hoping to make something.
At the beginning of the exploration, it was difficult, and many attempts were made, but it was rarely effective. However, I couldn't take it, so I repeated the deduction and changed the method. After years of grinding, I finally achieved success. In the meantime, analyze its structure, study its characteristics, and speculate on the reaction conditions and the preparation of raw materials.
Up to today, the development of this product has reached a critical trend. Looking at its journey, it is like sailing against the current. If you don't advance, you will retreat. Since it was first conceived, it has been a little obvious until today, and every step has been difficult, but every gain is also comforting. The hardships of the past are all the cornerstones of this moment, and it is hoped that there will be great achievements in the future, adding to the science of chemistry.

Product Overview

There is now a substance named N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide. This substance can be described as a newcomer in the field of organic synthesis. Its unique structure is based on quinazolinamide as the core, with iodine atoms added at the 6th position, and a specific aryl group at the 4th position. In the aryl group, there are chlorine atoms at the 3rd position, and the 4th position is modified by the (3-fluorobenzyl) oxygen group.
Looking at its development, after several years of exploration, researchers have repeatedly speculated on the conditional variables in experiments. From the raw materials carefully selected, through multi-step reaction convergence, each step is temperature control, speed regulation, and substrate ratio inspection. This compound has great potential in the direction of medicinal chemistry, or paves the way for the creation of new drugs, and has a ray of hope for conquering difficult diseases; in the field of materials science, or for new functional materials to create a new path, with a unique structure to give materials different properties, hoping to bring opportunities for innovation in related fields, promising prospects.

Physical & Chemical Properties

There is a substance named N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamine, whose physical and chemical properties are crucial. The form of this substance is either solid or liquid, and it must be carefully inspected. The number of its melting point and boiling point is related to the change of the state of this substance, which cannot be ignored. Solubility is also an important property. The amount of solubility in various solvents affects its dispersion and reaction rate in the reaction system.
Furthermore, its chemical stability also needs to be carefully analyzed. In the air, in different pH environments, or under heat and light, whether it is easy to react, and whether there is a risk of decomposition and deterioration. And how its polarity is, it also affects the strength of its interaction with other things. These physical and chemical properties, when preparing, storing, and applying this thing, are all key considerations, which are related to the success or failure of everything, and must be carefully studied.

Technical Specifications & Labeling

The name of this product is N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamine. The process specifications and identification (product parameters) of this product are the key. The process specifications are related to the preparation method, and it is necessary to carefully control all aspects, from the selection of raw materials to the reaction conditions, such as temperature, duration, and reagent dosage, to obtain a good product. In terms of identification, the product parameters need to be precisely stated, such as the proportion of ingredients and the geometry of purity, for the user to understand. In this way, strict adherence to the process specifications and accurate identification of product parameters can obtain this product. It is excellent and has reliable value in scientific research and application.

Preparation Method

The method of preparing N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide is related to the raw materials and production process, reaction steps and catalytic mechanism. Preliminary raw materials, 3-chloro-4-hydroxyaniline, 3-fluorobenzyl halide, etc. are properly measured. It is dissolved in a suitable solvent, such as N, N-dimethylformamide, supplemented by alkali agents such as potassium carbonate. Temperature control, in moderate heat, 3-chloro-4-hydroxyaniline and 3-fluorobenzyl halide nucleophilic substitution to obtain intermediate products.
Then react with iodoquinazoline derivatives. According to a specific ratio, to suit the catalysis of catalysts, such as palladium catalysts. Adjust the reaction environment, or change the polarity of the solvent, change the temperature, to obtain the target product. After the reaction is completed, it is separated and purified, extracted, column chromatography, etc. In this way, pure N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide can be obtained, which can be used as a preparation method for the product.

Chemical Reactions & Modifications

Recently, the chemical reaction and modification of N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide have been studied. The reaction characteristics of this compound are very different, and the reaction mechanism must be studied in detail in order to optimize it. In the past, the same type of reaction, the medium, temperature and catalyst variables often caused very different results.
When the temperature is controlled in a moderate range, the reaction rate is relatively stable, but the purity of the product is not ideal. Changing the polarity of the medium has a significant impact on the reaction process, and the conformation of the product is also slightly different. In order to improve the effect of modification, try various catalysts. A new type of catalyst has emerged, which not only accelerates the reaction, but also greatly improves the regularity of the product.
With time and detailed analysis of the influence of various factors, it is expected to obtain a precise reaction path, achieve excellent output and optimized characteristics of this chemical, and demonstrate practical value in various fields of chemical industry.

Synonyms & Product Names

Today there is a thing named N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide. It is unique in the field of chemistry. The name of this thing is synonymous with the name of the commodity, which is particularly critical.
Although its scientific name is long, if you want to find its synonymous name, you can study the ancient books and study the predecessors in detail. Or in the relevant experimental records, see its different names, which may lead to the birth of synonymous names due to different customs and research focuses in various places.
As for the name of the commodity, think about the path of the market. Looking at its use, if it is used in pharmaceutical research and development, or according to its curative effect and disease, the appropriate trade name can be taken to attract the attention of the pharmaceutical industry. If it involves chemical production raw materials, it should also be determined according to their characteristics and application scope, so as to facilitate the exchange and promotion of the industry. In this way, when researching and applying this product, the name is clear and clear, and it does not hinder the communication and promotion of all parties.

Safety & Operational Standards

Nowadays, there are chemical substances called N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide, and their safety and operating standards cannot be ignored.
When synthesizing this substance, all steps must be strictly correct. The weighing of the material used must be accurate to the millimeter, so as not to make the slightest difference in the reaction. And the required temperature and duration of the reaction must also be followed according to the law. If the temperature is too high, it may cause the decomposition of the substance, damage the purity, and even the safety of life; if the temperature is too low, the reaction will be slow or give up halfway.
When operating, protective gear must be provided. Special protective clothing must be worn to prevent substances from contaminating the skin and eroding its texture. Wear goggles to protect the naked eye from injury. A mask is also indispensable to prevent the volatilization of substances into the lungs.
Store this thing in a dry and cool place, away from hot fire and high temperature, and away from all kinds of flammable and explosive things. It must also be hidden in an airtight container and marked with a clear name to make people aware of its properties to prevent misuse.
In case of an accident, if it is accidentally contaminated, rinse it with plenty of water quickly, and then seek medical treatment. If the substance leaks, evacuate everyone immediately. Practitioners quickly use protective equipment to clean up the scene and do not allow it to spread to cause greater danger. This is the essence of N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6 -iodine-4 -quinazolinamide safety and operation, which cannot be ignored.

Application Area

N- {3-Chloro-4- [ (3-Fluorobenzyl) Oxy] Phenyl} -6-Iodo-4-Quinazolinamine This compound has a wide range of application fields. In the field of medicine, its unique chemical structure may be used to further explore its efficacy on specific diseases, such as for the development of new drugs for intractable diseases, hoping to have the effect of cracking chronic diseases. In the field of materials science, it may be used to develop new materials with special functions and use them as building blocks for high-end technical products. Although the current research is still in the exploratory stage, with time and in-depth research, its potential for pharmaceutical and material applications is limitless, and it is expected to bring many innovations and breakthroughs to the world and benefit all people.

Research & Development

I have tasted the industry of chemical industry, and I have been making great progress, and new products have emerged. Today there is a thing named N- {3-Chloro-4- [ (3-Fluorobenzyl) Oxy] Phenyl} -6-Iodo-4-Quinazolinamine. I have observed it and investigated its properties in detail. In various experiments, I know its physical and chemical quality, and understand its reaction rules.
Explore the method of its synthesis, or find a better way, increase its yield, and improve its purity. If such new substances, or in the field of medicine, can develop great plans, cure various diseases, and benefit the common people. Or in the field of materials, innovate the texture and make achievements.
We study diligently and try various methods, hoping to gain new knowledge. With time, we will be able to make the research and development of this product a step further, and contribute to the advancement of science and the benefit of people's livelihood. Make this N- {3-Chloro-4- [ (3-Fluorobenzyl) Oxy] Phenyl} -6-Iodo-4-Quinazolinamine, can carry forward its growth, develop its use, and live up to the heart of research.

Toxicity Research

Taste and hear the nature of all kinds of herbs, each has its own merits and demerits; the poison of five stones may also see special effects. Today's researchers study N- {3-Chloro-4- [ (3 - Fluorobenzyl) Oxy] Phenyl} -6 - Iodo-4 - Quinazolinamine. The toxicity of this substance is similar to Mount Tai.
Now when you study it, you must carefully observe its response to things, and when you apply it to insects, you will observe the change of its vitality, depending on its behavior, diet, and reproduction. Placed in plants and trees, you will observe its prosperity, growth, and wither. Then take various ancient books as a reference to examine the nature of the same kind in the past, and refer to its similarities and differences.
However, the study of toxicity is related to the lives of the people, so be cautious. Don't take it lightly and act rashly. You must wait until all kinds of tests are completed, and the analysis is clear and the judgment is correct before you can know its good and evil, and judge whether it can be used in the public. In the people's livelihood industry, you must not leave disasters behind, so as to protect the safety of the world's living beings.

Future Prospects

In the future, the development of N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide has a great future. Although it is still a preliminary exploration, the progress of science is changing with each passing day. It may be able to show wonders in the field of pharmaceutical research and development.
Looking at this substance, it has a unique structure and wonderful characteristics. In the coming year, scholars can study its properties in detail and explain its pharmacological ability. If the research is successful, it may be able to cure diseases and diseases for the sick, such as Lingdan to help the world.
And technology advances with the day, and research methods improve the essence. From the microscopic of molecules to the clinical experience, with time, we will be able to understand the whole picture, make it in the forest of medicine, show its extraordinary ability, benefit all people and benefit all lives, and eventually become an important tool for the future medical outlook.

Historical Development

Fu N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide is a key object in the study of chemical products. Looking at the past, the evolution of chemistry has gone from ignorance to subtlety, and this compound has also undergone many changes.
At first, only a little knowledge of its basic composition, with the deepening of research, the analysis of its molecular structure gradually became more accurate. In the past, the equipment was simple and the investigation was difficult, but scholars were not discouraged and worked tirelessly.
With the passage of time and the improvement of technology, the understanding of its reaction characteristics and synthesis path is becoming more and more clear. From crude methods to exquisite craftsmanship, every step gathers wisdom. Its potential uses in medicine, materials and other fields have gradually emerged along with the course of history. Today, looking back at its historical development, it can be seen that although the road of chemical research is full of thorns, it has achieved fruitful results. This compound may have even more outstanding performance in the future and bloom in various fields.

Product Overview

There is now a thing called N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide. This is the result of my chemical research.
Looking at its structure, it is quite unique. It contains chlorine, fluorine, iodine and other halogen elements, which are matched with each other to make the molecular properties unique. 3-chlorine is connected to 4- [ (3-fluorobenzyl) oxy] phenyl, and together with 6-iodine and 4-quinazolinamide, it forms a molecular skeleton. This delicate combination endows the substance with special physical and chemical properties.
After many experiments, it shows significant activity in specific chemical reactions, or has potential application value in drug development, material science and other fields. I will continue to study, hoping to dig deeper into its characteristics and contribute to the development of science, so as to make the best use of it and benefit the world.

Physical & Chemical Properties

Today there is a substance called N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide. Its physical and chemical properties are quite crucial. The state of this substance, whether it is a solid state, depends on its color, or shows a specific color, depending on its purity. Its melting point is an important physical characteristic, which is related to the phase transition of this substance at any temperature. Furthermore, the solubility cannot be ignored. In various solvents, the degree of solubility or insolubility affects its subsequent application. In terms of chemical properties, the interaction of atoms and groups in its structure determines its reactivity. Or it can react with specific reagents to form new substances. In the study, the physical and chemical properties of this substance should be carefully investigated in order to better grasp its characteristics and lay the foundation for subsequent application and development.

Technical Specifications & Labeling

Today there is a product called N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide. Its process specifications and identification (product parameters) are related to the quality and application of this product.
On the process specifications, from the selection of raw materials, it is necessary to choose the product with high purity and less impurities. The synthesis method must follow precise steps, and the reaction conditions such as temperature, pressure, time, etc. must be strictly controlled. Each step must not be different in order to obtain a product with uniform texture and stable performance.
As for the identification, the product parameters should be detailed. The proportion of the elements contained, the geometry of the molecular weight, and even the physical properties, such as color, morphology, melting point, boiling point, etc., should be clearly marked. In this way, the user can understand its characteristics, use it correctly, and exert its due effect in the fields of medicine and chemical industry, without the risk of misuse.

Preparation Method

The method of preparing N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide is the first to specify the raw materials. The main ones are 3-chloro-4-hydroxyaniline, 3-fluorobenzyl halide, 6-iodine-4-chloroquinazoline, etc.
In the process of preparation, 3-chloro-4-hydroxyaniline and 3-fluorobenzyl halide are first nucleophilic substitutions catalyzed by suitable solvents and bases to obtain 3-chloro-4- [ (3-fluorobenzyl) oxy] aniline.
Times, 6-iodine-4-chloroquinazoline and the obtained product are combined under suitable conditions, such as heating, selecting a suitable catalyst, and then undergoing nucleophilic substitution. After the reaction is completed, the steps of separation and purification, such as column chromatography, recrystallization, and removal of impurities, are obtained. Among them, controlling the reaction temperature, time and material ratio is related to the yield and purity. It is also necessary to carefully observe the reaction process and adjust it in a timely manner in order to refine this product.

Chemical Reactions & Modifications

The wonders of chemical industry are related to reaction and change, especially in N - {3 - Chloro - 4 - [ (3 - Fluorobenzyl) Oxy] Phenyl} -6 - Iodo - 4 - Quinazolinamine.
The reaction of this compound is like ancient alchemy, and the temperature and formula must be exquisite. Its chemical changes are not the clutch of single molecules, but also the transformation of properties. In the reaction, the atoms of chlorine, fluorine, and iodine, such as soldiers, are in their positions to change the structure.
Its changing properties are also like that of a good craftsman carving jade, and the temperament is very different between the pondering. Either increase its stability, or increase its activity, all depend on the beauty of the reaction. This change cannot be ignored by human beings, but is the profound meaning of chemistry. Only by deeply studying its reaction mechanism and gaining insight into the method of changing properties can this thing be controlled. It is used for all kinds of purposes, such as medicine in medicine and creation in engineering.

Synonyms & Product Names

I am committed to the research of N - {3 - Chloro - 4 - [ (3 - Fluorobenzyl) Oxy] Phenyl} - 6 - Iodo - 4 - Quinazolinamine. The synonyms and trade names of this substance are related to its cognition and application.
In the field of chemistry, there are many things, and they are common. Synonyms, either based on the characteristics of their structure or the way they originate from reactions, are called by chemists according to their nature and composition, all of which are to accurately describe their essence. And the name of the product is promoted and marked by the merchant, which is convenient for market circulation.
N - {3 - Chloro - 4 - [ (3 - Fluorobenzyl) Oxy] Phenyl} - 6 - Iodo - 4 - Quinazolinamine synonym, analyzed from the chemical structure, or named after its atomic arrangement and functional group characteristics. The trade name is in response to commercial needs, pursuing simplicity, easy-to-remember, unique and eye-catching, in order to attract attention to the market.
A detailed study of this substance synonym and trade name can help the academic community communicate smoothly, and also make the business operate smoothly in the market, and play an important role in the development and application of chemical products.

Safety & Operational Standards

Nowadays, there is a chemical substance N - {3 - Chloro - 4 - [ (3 - Fluorobenzyl) Oxy] Phenyl} - 6 - Iodo - 4 - Quinazolinamine, and its safety and operating standards are of paramount importance.
When operating, it must be done in a well-ventilated place. This substance may have certain chemical activity. If the ventilation is not smooth, harmful gases will accumulate, which may endanger the health of the operator. In addition, the operator needs suitable protective equipment, such as protective clothing, gloves and goggles. Because the substance may be irritating to the skin, eyes, or penetrate through the skin, it is first and foremost to protect yourself.
For storage, it should be placed in a cool, dry place and away from fire sources. Due to the risk of flammability or chemical stability of chemical substances, a suitable storage environment can ensure its quality and avoid accidents such as fire. When taking it, follow the precise measurement tools and standard steps. Do not overdose or be hasty to prevent the chemical reaction from getting out of control and causing safety accidents.
If you accidentally come into contact with this substance, if it touches the skin, rinse it with plenty of water quickly, and then seek medical attention according to the situation; if it enters the eyes, you need to rinse it with water immediately and seek medical help urgently. In case of material leakage, when evacuating the surrounding people quickly, the operator wears professional protective equipment, and cleans it up according to the established procedures. Do not panic and disorder.
In short, the handling and handling of N - {3 - Chloro - 4 - [ (3 - Fluorobenzyl) Oxy] Phenyl} - 6 - Iodo - 4 - Quinazolinamine must adhere to strict safety and operating practices to ensure the safety of personnel and the environment.

Application Area

There is now a substance named N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide. This substance has its uses in various fields. In the field of medicine, many studies have been conducted to investigate its efficacy on diseases, or it can help physicians find new ways to treat diseases and treat patients. In the field of agriculture and planting, explore its impact on crop growth, or it can increase agricultural production and protect crops from diseases. In the field of materials, consider its characteristics, or make new materials to meet diverse needs. These are all fields of application, waiting for our generation to study in detail, so as to make the best use and contribute to the development of the world.

Research & Development

I have been engaged in the research of chemical products for a long time, and recently focused on the research and development of N- {3 - Chloro - 4 - [ (3 - Fluorobenzyl) Oxy] Phenyl} -6 - Iodo - 4 - Quinazolinamine. This compound has unique characteristics and may have broad application prospects.
The road of research and development is very difficult. To obtain its pure state, it is necessary to go through many exquisite experiments to control the reaction conditions, such as temperature, duration, and raw material ratio. If there is a slight difference, it will affect the results. However, I will continue to study, try again and again, and strive to break through.
Looking to the future, if this research is successful, it may set off changes in the fields of medicine, materials, etc., adding to the development of the industry. I will do my best to promote this compound from research to practical application, hoping to make progress and live up to my years of research.

Toxicity Research

Those who taste poison, the harm is very serious, which is related to life and safety, and must be observed. Today there is N - {3 - Chloro - 4 - [ (3 - Fluorobenzyl) Oxy] Phenyl} -6 - Iodo - 4 - Quinazolinamine This substance should be studied in detail.
Toxicity research is related to people's livelihood. It is necessary to observe its impact on life. If it is applied to insects, poultry and livestock, observe its behavior and physiological changes. Also explore whether it persists in the environment, whether it is difficult to eliminate, whether it accumulates in water and soil, and is transmitted in the food chain.
Observe its chemical structure, chlorine, fluorine, iodine and other elements, or cause toxicity. And such compounds with complex structures are metabolized in living organisms, or produce strange intermediates, which exacerbate toxicity. Strict methods must be used to verify and clarify toxicity in many ways to ensure the well-being of the world and the environment.

Future Prospects

Today there is a substance called N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide. My generation is a researcher of chemical substances, observe this substance, observe its characteristics, and explore its mechanism.
Although its basic composition is only known at present, looking to the future, this substance may emerge in the field of medicine. Or it can be a drug introduction for difficult diseases, with its unique structure, it can precisely act on lesions. Or it has made achievements in materials science, endowing materials with new energy, strengthening their toughness and increasing their characteristics.
Although the road ahead is long and the geometry is unknown, we, the scientific researchers, must have enthusiasm, perseverance, and in-depth research. With time, we can fully develop the potential of this material, contribute to the future development, open up new frontiers, and live up to our expectations for the future.

Historical Development

Yu has dedicated himself to the research of chemical products. Recently, N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide has been studied. It is of great significance to my chemical research.
Looking back in the past, the progress of chemistry has been difficult step by step. Since the ancestors first entered the field of chemistry, many substances were unknown, but they were unremitting research. Later, people's understanding of chemistry gradually became clear, and various products were born. This research on N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide is the foundation of predecessors.
Past research, all kinds of attempts, success or failure, are all experience. After countless days and nights, repeated trials, adjustment of formulas, and optimization of processes, this result was finally achieved. The achievement of this product is not the work of one person, but the efforts of all researchers. Its birth also added to the progress of chemistry. It is hoped that it will be able to be used in various fields in the future, and then spread new chapters in chemistry.

Product Overview

Today there is a substance called N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide. The shape of this substance is colorless to slightly yellow crystalline powder. Looking at its properties, it is quite stable under normal temperature and pressure, but it may explode in case of open flame or hot topic. The preparation method is often made of specific organic compounds as raw materials through multi-step chemical reactions. First, an aryl halide and the corresponding alcohol are nucleophilic substitution under basic conditions to obtain an intermediate product containing benzyloxy group. Then this intermediate product and the compound containing iodine and quinazolinamide structure, under the action of a suitable catalyst, through the coupling reaction, the reaction temperature, time and the ratio of the reactants are carefully adjusted to obtain this target product. Its use is very wide, in the field of pharmaceutical research and development, or can be used as a potential drug intermediate, laying the foundation for the creation of new drugs; in the field of materials science, it may also help to improve the performance of some functional materials.

Physical & Chemical Properties

There is a substance called N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide. In terms of physical and chemical properties, this substance has its own unique characteristics. Its shape, or powder shape, is white and delicate, and it is pure in appearance. Its melting point, after precise determination, is within a certain range. This value is the key to determine its purity and characteristics. In terms of solubility, it shows a unique performance in specific solvents. Some organic solvents are soluble, while others are insoluble. This property is related to its application in different environments. Its chemical stability is also worth exploring. It is relatively stable at room temperature and pressure. However, when specific chemical reagents or conditions change, reactions can also occur, resulting in unique chemical changes. This is something that chemical researchers should investigate in detail.

Technical Specifications & Labeling

There is now a product named N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide. In the preparation method, the specific process specifications should be followed. The material selection needs to meet the precise specifications, the proportion of each component, and it should also be strictly adhered to. When reacting, parameters such as temperature and duration are all key, and the difference is very small.
As for the product identification, it is necessary to specify the parameters of each product in detail. From the chemical composition to the physical properties, from the purity standard to the scope of application, it should be clearly marked so that the reader can understand its properties and the user can obtain the method. Process specifications and labeling are related to the quality of the product and the safety of the user, which cannot be ignored.

Preparation Method

There is a method for preparing N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide, which is described in detail as follows. The raw materials are selected when they are pure and preferred. 3-chloro-4-hydroxyaniline, 3-fluorobenzyl chloride, etc. are all essential substances. In the synthesis process, 3-chloro-4-hydroxyaniline and 3-fluorobenzyl chloride are catalyzed by an appropriate agent at a suitable temperature to obtain 3-chloro-4- [ (3-fluorobenzyl) oxy] aniline. Then, this substance is reacted with iodoquinazoline derivatives under specific conditions, and the target product can be obtained through multi-step conversion. The reaction steps need to follow the procedures, control the temperature, and monitor the reaction process. Refining mechanism, the product is recrystallized, column chromatography and other methods to remove its impurities to obtain pure N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6 -iodine-4 -quinazolinamide, which can be used for various research and applications.

Chemical Reactions & Modifications

The chemical reaction and modification of the compound of N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide are the key to chemical research. The reaction of this compound is like the ancient method of alchemy, and the temperature and dose need to be precisely controlled.
In the reaction, the various components interact, just like the ancient art of war. Every time a chemical bond is broken and formed, it is a subtle change in the reaction. To seek the best effect of its modification is like exploring the delicate compatibility of ancient recipes.
Chemists are like those who search for treasures, carefully observe the phenomenon of the reaction, and think about the way of modification. Or adjust the reaction conditions, or add specific additives, in order to show more excellent properties of this compound. In this way, a new chapter can be opened in the field of chemistry, just like the ancients in the unknown, breaking new ground.

Synonyms & Product Names

Today there is a thing called N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide. This thing is the key to scientific research in the field of chemistry.
It is necessary to seek its synonyms and trade names. Due to the way of scientific research, the names are different, or cause confusion. If you can clarify synonyms, it is like holding a navigational needle, and you will not get lost in the vast sea of knowledge. The trade name cannot be ignored, it is related to market circulation, and it is a sign of its walking in the world.
To search for synonyms, you need to dig up classics and literature, just like salvaging beads in the long river of history; to find commodity names, you need to look at the market and visit merchants, just like searching for that unique sign in the streets and alleys of the market. In this way, you can have a comprehensive understanding of the object and move forward steadily on the road of scientific research, so as not to delay the process due to the complexity of the name.

Safety & Operational Standards

Today, there is a product called N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide. We are researchers of chemical substances. Its safety and operating practices need to be discussed in detail.
This product is related to safety and is the first protection. Anyone who comes into contact with it must wear suitable protective gear. Goggles are required to protect the eyes against the risk of splashing into the eyes; protective clothing is worn to protect the skin from damage; protective gloves must be worn to prevent direct touch. This is to avoid harm to the human body and ensure personal safety.
As for the operating specifications, first, when using this object, it should be well ventilated. Make the air flow smoothly, and the harmful gases that may be generated can be dissipated, so as to prevent their accumulation and hurt people. Second, be careful when operating, do not let this object spill. If there is any accidental spill, it should be cleaned up quickly according to the established method. Third, when using this object, the measurement must be accurate. Many may cause accidents, and at least it will not achieve the expected effect.
Furthermore, there are rules for storage. It should be placed in a cool, dry and ventilated place, away from fire and heat sources. Do not store with reactive substances to prevent them from interacting and causing danger.
Our chemical researchers are aware of the safety and operating practices of N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide. Keep in mind and follow the rules, so as to ensure the smooth progress of the experiment and protect the well-being of yourself and others.

Application Area

Fu N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide, a new substance made by modern chemistry. Its application field can be explored.
In the field of medicine, it may be helpful for curing diseases. Chemical substances can often be the basis of medicinal stones. This compound has a unique structure, or has the ability to regulate human physiology. Looking at its atomic combination, it may be combined with specific receptors in the body to achieve the effect of treating diseases, such as for anti-tumor research, hoping that it can control the reproduction of tumors.
In the field of agriculture and planting, it is also possible. Or it can be developed into a new type of agricultural agent to protect crops from diseases and pests. Its chemical properties may interfere with the physiology of pests, inhibit the growth of pathogens, and maintain the prosperity of crops.
And in the field of material science, it is also possible. Or modified and prepared to make special materials with unique physical and chemical properties, which will contribute to the prosperity of industry.

Research & Development

The current research on the product of N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide is related to research and progress. The research of this product requires detailed investigation of the relationship between its chemical properties and structures. First analyze the structure of its molecules, clarify the position and energy of each group, and explore its chemical reaction state. Repeat the method of studying its combination, seek the path of high efficiency and purity, and control the reaction, such as temperature, pressure, agent ratio, etc., in order to increase its yield and purity.
For the extension of its application, consider its potential in the fields of medicine and materials. In the medicine, it may be an agent for treating a certain disease, study the interaction between it and the target, and test its efficacy and safety. In the material or in the new material, such as toughness, corrosion resistance, etc. After repeated tests and analysis, this product has achieved remarkable results in the way of research and progress, adding new strength to various domains and becoming a useful material and good medicine.

Toxicity Research

In the development of medicine, toxicological investigation is essential. There is a substance today called N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide. In the study of toxicology, it is very important.
To study this substance, it is necessary to study its properties in detail. Observe the structure of its molecules, analyze its response to other substances. Observe the changes in its entry into the body, or in the viscera and meridians. Examine ancient books, refer to modern experiments, hope to understand the location of its poison and the severity of its harm.
Examine its presence in cells in detail to see if it damages its structure or disrupts its function. Also explore its effect in animals, and check that there are no abnormalities or diseases. Strive to understand the toxicity of this substance, for future use, or medical or other means, predict its advantages and disadvantages, avoid disasters, protect the health of the people, and promote the progress of research.

Future Prospects

I have devoted myself to chemical research, and recently focused on N- {3-Chloro-4- [ (3-Fluorobenzyl) Oxy] Phenyl} -6-Iodo-4-Quinazolinamine this compound. It is interesting to see its delicate structure and characteristics.
Looking to the future, this compound is expected to emerge in the field of medicine. Or it can use its unique structure to develop new drugs to cure various diseases and relieve the pain of patients. Or make achievements in materials science and contribute to the research and development of new materials.
Although the road ahead may be difficult, our scientific researchers are determined to explore. We hope to make unremitting efforts to reveal more mysteries of this compound, so that it can shine in the future and contribute to human well-being.

Where to Buy N-{3-Chloro-4-[(3-Fluorobenzyl)Oxy]Phenyl}-6-Iodo-4-Quinazolinamine in China?

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Frequently Asked Questions

As a leading N-{3-Chloro-4-[(3-Fluorobenzyl)Oxy]Phenyl}-6-Iodo-4-Quinazolinamine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the chemical structure of N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodo-4-quinazolinamine

This is the name of an organic compound, and its chemical structure is complex, which can be gradually analyzed according to the naming rules. "N - {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide", with quinazolinamide as the parent structure, its 4-position is connected with a phenyl group containing a specific substituent, 3-chloro, 4- [ (3-fluorobenzyl) oxy] modified this phenyl group; 6-position is connected with an iodine atom. Quinazolinamide has a bilicyclic structure, contains nitrogen atoms, and is basic, which is of great significance in organic synthesis and drug development. 3-Chlorine is a hydrogen atom at the 3-position of the benzene ring substituted by a chlorine atom; (3-fluorobenzyl) oxygen, which is a benzyl oxygen connected to the 4-position of the benzene ring, and the 3-position of the benzyl ring is substituted by a fluorine atom. In this way, the structure of this compound is clear, and the positions and types of each substituent are determined. In the fields of chemical research and medicine, the structure can be studied according to its properties, activities and reactions, which lays the foundation for the creation of new drugs and the exploration of new synthesis

What is the main use of N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodo-4-quinazolinamine

N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamine, this is an organic compound. Looking at its structure and characteristics, it can be seen that its use is mainly in the field of pharmaceutical research and development.
In the exploration path of modern medicine, many organic compounds are the cornerstones of the creation of new drugs. This compound has a unique structure, in which halogen atoms such as chlorine, fluorine, and iodine, as well as specific structural fragments such as quinazolinamide, give it potential biological activity. Or it can interact with specific targets in organisms, such as binding with certain proteins and enzymes, and then show the efficacy of treating diseases.
For example, in the long road of anti-tumor drug development, many compounds containing quinazoline structures have emerged. Quinazoline compounds can specifically act on targets such as tyrosine kinase overexpressed in tumor cells, blocking the proliferation and metastasis signaling pathways of tumor cells, so as to inhibit tumor growth. The iodine atoms in this compound can adjust the electron cloud distribution of the molecule and enhance its binding force with the target; the introduction of fluorine atoms can often improve the metabolic stability and fat solubility of the compound, which is conducive to its passage through the biofilm and better drug efficacy.
Or in the exploration of antibacterial drugs, the structural properties of the compound may make it inhibitory to some bacteria. Bacterial cell wall synthesis, protein synthesis and other key physiological processes may be blocked due to the action of this compound, eventually resulting in bacterial growth inhibition and even death.
Although the exact results of its experimental research are not known, in terms of the potential contained in its structural characteristics, it is very likely to become a key "puzzle" in the search for new therapeutic drugs in the field of medicine, providing new ideas and opportunities for solving various diseases.

What are the synthesis methods of N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodo-4-quinazolinamine

The method of synthesizing N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide often follows the following methods.
First, 4-chloro-6-iodoquinazoline is used as the starting material. First, 4-chloro-6-iodoquinazoline and 3-chloro-4-hydroxybenzaldehyde are mixed in a suitable organic solvent, catalyzed by a base, such as potassium carbonate, etc., through nucleophilic substitution reaction to obtain the corresponding etheride. The etheride is then reacted with a suitable amine source, such as an amine containing 3-fluorobenzyl group, under suitable conditions. The amine group attacks the chlorine atom on the quinazoline ring and undergoes nucleophilic substitution, and then synthesizes the target product.
Second, 3-chloro-4- [ (3-fluorobenzyl) oxy] aniline is used as the starting material. First, it is reacted with a suitable acylating agent to obtain an amide intermediate. This intermediate is then cyclized, or a suitable cyclizing agent, such as polyphosphoric acid, is used to promote the cyclization of the molecule to form a quinazoline ring structure. After that, at a specific position on the ring, iodine atoms are introduced through an iodine substitution reaction, and the target product can be obtained by using an iodine source and appropriate catalysts, such as potassium iodide and hydrogen peroxide systems.
Third, 6-iodine-4-quinazolinone is used as the starting material. It is first halogenated to introduce chlorine atoms, and halogenated reagents such as phosphorus oxychloride are commonly used. The obtained haloquinazolinone is then reacted with 3-chloro-4- [ (3-fluorobenzyl) oxy] aniline, and through the nucleophilic substitution process, the target N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6 -iodine-4 -quinazolinamide is generated.
All synthesis methods have their own advantages and disadvantages. According to the actual situation, consider the availability of raw materials, the difficulty of reaction conditions, and the high or low yield. Choose the appropriate one and use it.

What are the physical properties of N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodo-4-quinazolinamine

N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamine, this is an organic compound. Looking at its structure, it is composed of quinazolinamine core structure, connected with specific substituted phenyl groups. Halogen atoms such as chlorine, fluorine, iodine and benzyloxy groups are distributed in it, and this structure gives it unique physical properties.
First, its physical state is described, under normal temperature and pressure, or it is a solid powder. Due to the interaction of van der Waals force and hydrogen bonds between the molecules, the molecules are arranged in an orderly manner and take on the shape of a solid state. In terms of melting and boiling point, the melting point and boiling point may be relatively high due to the large number of atoms in the molecule, the complex structure, and the strong intermolecular forces. To make the molecule overcome the intermolecular forces and realize the phase state transition requires more energy.
In terms of solubility, due to its halogen atom, aromatic ring and other hydrophobic groups, the solubility in water is poor. Water is a polar solvent, and the polarity of this compound is relatively weak. According to the principle of "similar compatibility", it is difficult to dissolve in water. However, in organic solvents such as dichloromethane, chloroform, N, N-dimethylformamide (DMF), it may have some solubility. Organic solvents such as dichloromethane and chloroform have moderate polarity and good solubility, and can form intermolecular forces with compound molecules to promote dissolution; DMF is a strong polar organic solvent, which can interact with groups containing nitrogen and oxygen atoms in compounds to form hydrogen bonds, etc., to enhance solubility.
Its density may be greater than that of water. Due to the large relative atomic weight of iodine atoms in the molecule, the overall molecular weight increases, and the molecular structure is compact, resulting in a large unit volume mass.
In addition, the compound contains a conjugated aromatic ring structure, or has certain optical properties. Under the irradiation of specific wavelengths of light, it may be absorbed and emitted. It can be used in the research of optical materials and other fields. Due to its complex structure and a variety of active groups, it may exhibit unique chemical activities in chemical reactions, providing a research foundation for organic synthesis, drug development, and other fields.

N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodo-4-quinazolinamine

Today there is a product called N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide. The prospect of this product in the market is related to many aspects.
In the field of Guanfu Medicine, such compounds often have unique pharmacological activities. Because of their delicate structure, they may be combined with specific biological targets to play a therapeutic effect. For example, in the development of anti-tumor drugs, many quinazoline-containing structures have emerged, which may inhibit the proliferation of tumor cells and induce their apoptosis. This N - {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide, if it can show outstanding performance in pharmacological research, will be favored by the pharmaceutical industry, and the market prospect is quite promising.
As for the field of pesticides, there are also opportunities. Today's demand for high-efficiency, low-toxicity and environmentally friendly pesticides is increasing. The structural characteristics of the compound, or its insecticidal and bactericidal effects, if properly developed, it is expected to become an alternative for new pesticides and open up a new market.
However, its market prospect is not smooth. The difficulty of synthesis is the primary consideration. If the synthesis steps are complicated and expensive, large-scale production and marketing activities will be hindered. Furthermore, safety assessment is also crucial. Whether it is used in medicine or pesticides, it is necessary to ensure that it does not pose significant harm to the human body and the environment. Only through rigorous safety tests can one be eligible for market entry.
In conclusion, N - {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6-iodine-4-quinazolinamide has both opportunities and challenges in the market prospect. If we can overcome the problems of synthesis and safety, we will be able to shine in the fields of medicine, pesticides, and gain a place in the market.