N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-iodoquinazolin-4-amine

This is the name of an organic compound, and its chemical structure is quite complex. It is described in the style of the ancient classical saying of "Tiangong Kaiwu", and its structure is solved in about 500 words. The following is a detailed description.
This compound is named "N- (3-chloro-4- (3-fluorobenzoxy) phenyl) -6-ioquinazoline-4-amine". The first view is "quinazoline", which is the core parent nucleus, just like the cornerstone of a building. Quinazoline has a double-ring structure, one is a six-membered benzene ring, and the other is a nitrogen-containing six-membered heterocycle. The two rings are combined and very stable.
At the 6th position of the quinazoline parent nucleus, an iodine atom is connected, and the iodine atom is like a unique decoration, giving the molecule different properties. The "amine" group connected to the 4th position is also a key part, and the amine-NH2O is active and active, often playing a key role in chemical reactions.
Then look at the "N- (3-chloro-4- (3-fluorobenzoxy) phenyl) " part connected to the amine group. "Phenyl" is a hexavalent carbon ring with aromatic properties. There is a chlorine atom substituted at the 3rd position of the benzene ring, and "3-fluorobenzoxy" at the 4th position. " Benzoxy "is a benzyl group connected to oxygen. The benzyl group is also a phenyl group connected to a methylene-CH 2O -, and the third position of this benzyl group has a fluorine atom substitution. Both fluorine and chlorine atoms are electronegative, which affects the distribution of molecular electron clouds, and then affects the reactivity and physical properties of the compound.
This compound has a delicate structure and interacts with various parts. Different substituents endow it with unique chemical and physical properties. It may have important uses in organic synthesis and medicinal chemistry.

N- (3-chloro-4- (3-fluorobenzyloxy) phenyl) -6-iodoquinazoline-4-amine is an important part of the physical rationality of this compound, and it is an important part of the study of nexus. Its outer layer is often solid-shaped, which is caused by the interaction of molecules. It has a certain degree of cohesion.
and melting, the melting of compounds is specific. Due to the particularity of its molecules, each atom interacts with each other with a common force such as,, etc., to form a fixed lattice. The external lattice degree rises to a certain value, which is enough to overcome the lattice energy, the lattice disintegrates, and the material is solidified from the liquid. This specific degree is called melting.
Furthermore, solubility is also one of the important factors. In common soluble solutions, such as dichloromethane, N, N-dimethylformamide, etc., its solubility is poor. In dichloromethane, or due to the compatibility of dichloromethane's non-toxic and molecular size compounds, the compounds have a certain solubility; in N, N-dimethylformamide, the solubility may vary due to molecular interactions.
In addition, the density is also one of the physical properties. The density depends on the weight of the molecule and the density of the molecular arrangement. Compound molecules contain chlorine, fluorine, iodine and other elements with a large atomic weight, and the arrangement of the molecules determines the amount of their position, resulting in a specific density value.
The physical properties of this compound are determined by its fine molecules, and play an indispensable role in many fields such as chemical synthesis and chemical research.

N- (3-chloro-4- (3-fluorobenzyloxy) phenyl) -6-iodoquinazoline-4-amine, this compound is an important compound in the field of organic synthetic chemistry. It has a wide range of main uses and occupies a key position in the process of pharmaceutical research and development.
In the field of anticancer drug research, it is often selected as a lead compound. The structure of quinazoline has high affinity with specific targets in many tumor cells, such as some tyrosine kinases. By modifying and optimizing the structure of this compound, new anticancer drugs with inhibitory effects on key processes such as tumor cell proliferation, migration and angiogenesis can be obtained, providing a new opportunity to solve cancer problems.
In the field of antimicrobial drug exploration, it also shows potential. Scientists speculate that the interaction of halogen atoms such as chlorine, fluorine and iodine in the structure with specific bacterial targets may destroy bacterial cell walls, cell membrane synthesis, or interfere with bacterial protein and nucleic acid synthesis, thus achieving antibacterial purposes and opening up the way for the development of new antibacterial drugs.
In the creation of pesticides, such compounds may become active ingredients of high-efficiency and low-toxicity pesticides. With the help of the unique mechanism of action against harmful insects and plant pathogens, precise prevention and control can be achieved, negative impact on the environment can be reduced, and sustainable agricultural development can be contributed.
In summary, N- (3-chloro-4- (3-fluorobenzyloxy) phenyl) -6-iodoquinazoline-4-amine is of great significance in the field of medicine and pesticides, and brings hope for solving problems related to human health and agricultural production. It is a compound of great research and development value.

The synthesis of N- (3-chloro-4- (3-fluorobenzoxy) phenyl) -6-iodoquinazoline-4-amine is a key study in organic synthetic chemistry. The synthesis of this compound often involves multiple steps, and each step needs to be carefully controlled to obtain it.
The initial step may require the preparation of key intermediates. Or 3-chloro-4-hydroxybenzaldehyde and 3-fluorobenzyl halide can be prepared by nucleophilic substitution in an alkaline environment to obtain 3-chloro-4 - (3-fluorobenzoxy) benzaldehyde. Bases such as potassium carbonate, in suitable organic solvents such as N, N-dimethylformamide (DMF), can assist in this reaction. When reacting, pay attention to the temperature and reaction time to ensure the purity and yield of the product.
After obtaining 3-chloro-4- (3-fluorobenzoxy) benzaldehyde, it can react with guanidine or its derivatives to form a quinazoline ring through cyclization. This cyclization reaction may require the assistance of acidic or basic catalysts. If an alkaline catalyst, such as sodium ethanol, is used to heat the reaction in an ethanol solution, it can be cyclized to obtain 4-aminoquinazoline derivatives.
The obtained 4-aminoquinazoline derivatives can be introduced into iodine atoms by halogenation reaction. Commonly used halogenating reagents, such as N-iodosuccinimide (NIS), are reacted in suitable organic solvents such as dichloromethane under mild conditions to introduce iodine atoms at the 6-position of the quinazoline ring.
The whole process of synthesizing N- (3-chloro-4- (3-fluorobenzoxy) phenyl) -6-iodoquinazoline-4-amine requires precise regulation of the reaction conditions at each step, including temperature, reaction time, reagent dosage and purity. And the product after each step of the reaction needs to be purified, such as column chromatography or recrystallization, to remove impurities, improve the purity of the product, and finally achieve the purpose of high-efficiency synthesis of this compound.

It is not easy to discuss the safety of N- (3-chloro-4- (3-fluorobenzyloxy) phenyl) -6-iodoquinazoline-4-amine. This compound, or a new product, has not been widely used in the world, and we know nothing about it.
The safety of the husband is the first to be involved in toxicity. However, in order to understand its toxicity, it must go through many complicated tests. Observe the past, or test it on animals, and observe the changes in their body shape, behavior, and organs after eating this compound. If the animal being tested is eaten and is weak, its body is weak, and its organs are damaged, it can be seen that this compound is quite toxic and harmful to the body of living beings.
Furthermore, consider whether it has mutagenic properties. If it can cause genetic mutation in organisms, or cause inherited diseases or teratogenesis, this is also a serious harm. It is necessary to use subtle methods to explore its impact on the genetic level.
Also, consider its impact on the environment. If this substance flows into the nature, it cannot be ignored in the water and soil, insects, fish, birds and beasts. Or in the water and swamp, killing fish and shrimp; or in the soil, harming the life of plants and trees.
However, in the current situation, we do not have detailed test data, and it is difficult to assert its safety. Or in the future, all tests will be completed before we can clarify the advantages and disadvantages of this N- (3-chloro-4- (3-fluorobenzyl) phenyl) -6-iodoquinazoline-4-amine in living beings and the environment, and judge its safety.