N 4 Chloro 5 Iodo 7h Pyrrolo 2 3 D Pyrimidin 2 Yl 2 2 Dimethylpropanamide

The structure of this compound is quite complex. Among them, "N- (4-cyano-5-chloro-7H-pyrrolido [2,3-d] pyrimidine-2-yl) ", in this part, the pyrimidine ring is the core structure, which is connected to a specific group at the 2nd position, with a cyano group at the 4th position and a chlorine atom at the 5th position. The "2,2-dimethylpropionamide" part is based on propionamide and has two methyl substitutions at the 2nd position.
Overall, this compound is formed by a specific connection between a nitrogen-containing heterocycle and an amide structure. The nitrogen-containing heterocyclic part exhibits a specific electron cloud distribution and spatial configuration, which may have a significant impact on the physicochemical properties and biological activities of the compound. The amide part may also participate in intermolecular interactions, such as the formation of hydrogen bonds, which play a key role in the behavior of the compound in a specific environment. The uniqueness of this structure may endow the compound with specific physical, chemical and biological properties, which may have potential applications in pharmaceutical chemistry, organic synthetic chemistry and other fields.

N- (4-nitrogen-5-azole-7H-pyrrolido [2,3-d] pyrimidine-2-yl) -2,2-dimethylpropionamide, which has a wide range of uses. In the field of medicine, it is often used as a key intermediate to assist in the development of new drugs. For example, in the development of anti-tumor drugs, its structural properties may precisely combine with specific targets of cancer cells, inhibit the proliferation of cancer cells, and bring hope to overcome cancer problems. In the development of antiviral drugs, it may also use its unique chemical structure to interfere with the process of viral replication and become a powerful weapon against viral infection.
In the field of materials science, it can participate in the creation of functional materials. Due to its special chemical activity and structure, it may endow materials with excellent optical and electrical properties. For example, in the preparation of organic optoelectronic materials, the addition of this substance may optimize the charge transport ability of the material, improve the luminous efficiency, and provide new opportunities for the development of optoelectronic devices such as organic Light Emitting Diodes (OLEDs).
In the field of pesticides, it may have potential biological activity. It may be used as an active ingredient of new pesticides to achieve efficient pest control by virtue of its specific action mechanism against insects and pathogens, and is relatively friendly to the environment, which is expected to contribute to the development of green agriculture.
With its unique chemical structure, this compound has shown broad application prospects in many fields such as medicine, materials, and pesticides. It is like a key to opening the door to innovation and development in many fields, waiting for researchers to explore and explore in depth.

To prepare N- (4-cyano-5-bromo-7H-indazolo [2,3-d] pyrimidine-2-yl) -2,2-dimethylpropionamide, the following ancient method can be carried out.
Take 4-cyano-5-bromo-7H-indazolo [2,3-d] pyrimidine-2-amine as the starting material and react it with appropriate protective reagents to protect its activity check point and prevent unnecessary reactions. If acylating reagents are used, they are treated under mild conditions to protect specific amino groups.
Times, prepare 2,2-dimethylpropionyl halide, such as 2,2-dimethylpropionyl chloride, take an appropriate amount of acid binding agent, such as triethylamine or pyridine, in a suitable organic solvent, such as dichloromethane or N, N-dimethylformamide, after protection, 4-cyano-5-bromo-7H-indazolo [2,3-d] pyrimidine-2-amine and 2,2-dimethylpropionyl halide Mix. Stir at controlled temperature to fully react the two, and obtain an intermediate product containing a protective group after nucleophilic substitution.
Subsequently, deprotect the group. Select the corresponding deprotection method according to the protective group. If it is protected by acyl groups, it can be hydrolyzed under basic conditions or released under acidic conditions, and the reaction conditions are carefully controlled to avoid damaging other parts of the product.
After the reaction is completed, the product is purified by ordinary separation and purification techniques, such as column chromatography, recrystallization, etc. The column chromatography is suitable for stationary phase and mobile phase, and it is separated according to the polarity difference between the product and the impurity; the recrystallization is selected with a suitable solvent to dissolve the product and then cool down and crystallize to obtain pure N- (4-cyanogen-5-bromo-7H-indazolo [2,3-d] pyrimidine-2-yl) -2,2-dimethylpropionamide. The whole process needs to pay attention to the precise control of the reaction conditions to prevent side reactions,

N- (4-cyanogen-5-azole-7H-pyrrolido [2,3-d] pyrimidine-2-yl) -2,2-dimethylpropionamide is an organic compound. Its physical properties are as follows:
In normal condition, it may be a white to off-white solid powder. Due to the appearance of many nitrogen-containing heterocycles and amide compounds, it appears powdery and light in color due to the interaction between molecules and crystal structure.
When it comes to melting point, the compound contains cyano, azole ring, pyrimidine ring and amide group in the molecule, etc. These groups can interact with each other through intermolecular hydrogen bonds, van der Waals forces, etc., so the melting point is presumed to be relatively high, or between 150 ° C and 250 ° C.
In terms of solubility, in view of the fact that the molecule contains polar cyano groups, amide groups, and non-polar methyl groups, it may have better solubility in polar organic solvents such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), because the two have strong polarity and can form hydrogen bonds or dipole-dipole interactions with compounds; in medium polar acetone, it may have some solubility; but in non-polar solvents such as n-hexane, the solubility is not good, because the non-polar part is difficult to interact with non-polar solvents.
The density of this compound is due to the molecular structure containing multiple heteroatoms and hydrocarbon groups, resulting in a larger molecular mass and a more compact spatial structure. It is estimated that its density is greater than that of water, about 1.2 - 1.4 g/cm ³. The inference of the physical properties of
is based on the common physical properties of the functional groups and compounds with similar structures contained in this compound. The actual properties may vary depending on the specific experimental conditions and determination methods.

N- (4-fluoro-5-chloro-7H-pyrazolo [2,3-d] pyrimidine-2-yl) -2,2-dimethylpropionamide, the safety of this chemical substance is related to many aspects.
Looking at its chemical structure, the compound contains halogen atoms such as fluorine and chlorine. Although halogen atoms can enhance the stability and specific activity of the compound, the halogen atoms are separated from the compound under certain conditions or form halogen ions. Some halogen ions are bioaccumulative and toxic, which can interfere with physiological processes in organisms, such as affecting enzyme activity and cell metabolism.
From the perspective of reactivity, the substance contains the structure of pyrazolopyrimidine, which is often highly reactive. During storage or use, in case of extreme conditions such as high temperature, strong acid, and strong base, or chemical reactions occur, new unknown substances are generated, and some new substances may be more toxic and corrosive, threatening the environment and human health.
Then look at its biological activity, because the compound contains a specific heterocyclic structure, or has effects on specific targets of organisms. In the field of pharmaceutical research and development, this may be an advantage, and drugs can be designed for specific disease targets. However, in the environment and organisms, unintended biological activity or adverse effects, such as interfering with the normal endocrine system of the organism, causing reproductive and developmental abnormalities.
Consider its stability, which determines the existence and behavior of the substance in the environment and organisms. If the stability is not good, it is easy to decompose in the natural environment, and the decomposition products may be more mobile and toxic than the original compounds, and are more likely to enter the organism and food chain, expanding the scope of pollution.
The safety of N- (4-fluoro-5-chloro-7H-pyrazolo [2,3-d] pyrimidine-2-yl) -2,2-dimethylpropionamide needs to be evaluated in terms of comprehensive structure, reactivity, biological activity, stability, etc. Rigorous experiments and long-term monitoring are required to fully understand its potential impact on the environment and human health.