What is the chemical structure of N- {5-chloro-4- [ (4-chlorophenyl) (cyano) methyl] -2-methylphenyl} -2-hydroxy-3,5-diiodobenzamide

The Chinese name of this compound is N- {5-chloro-4- [ (4-chlorophenyl) (cyano) methyl] -2-methylphenyl} -2-hydroxy-3,5-diiodobenzamide. According to its name, this is an organic compound.

Its core structure is benzamide, "N- {5-chloro-4- [ (4-chlorophenyl) (cyano) methyl] -2-methylphenyl}" part, indicating that a complex substituent is attached to the nitrogen atom of benzamide. In this substituent, there is a chlorine atom at position 5 of the benzene ring, a [ (4-chlorophenyl) (cyano) methyl] at position 4, and a methyl at position 2. "2-Hydroxy-3,5-diiodine" indicates that on the benzene ring of benzamide, position 2 is a hydroxyl group, and position 3 and 5 are replaced by iodine atoms respectively.

In summary, the compound has a complex structure, and the benzamide parent is modified by multiple substituents, showing a unique chemical structure.

What are the physical properties of N- {5-chloro-4- [ (4-chlorophenyl) (cyano) methyl] -2-methylphenyl} -2-hydroxy-3,5-diiodobenzamide

N- {5-chloro-4- [ (4-chlorophenyl) (cyano) methyl] -2-methylphenyl} -2-hydroxy-3,5-diiodobenzamide, is an organic compound. Its physical properties are particularly important, and it is related to the behavior of this substance in various environments.

In terms of its appearance, it is often in a solid state. This is due to the intermolecular force that makes the molecules arranged in an orderly manner and constitutes a relatively stable structure. As for the color, or white to off-white, this color state reflects the absorption and reflection characteristics of its molecular structure to visible light.

Melting point is actually a key physical property. The exact value of the melting point of the compound can be determined according to factors such as the strength of the intermolecular forces and the way of molecular accumulation. The determination of the melting point is helpful for the identification of this compound, and can also provide guidelines for the temperature control of its synthesis, purification and application.

In terms of solubility, in common organic solvents, their dissolution behavior varies. In some organic solvents, such as dichloromethane, N, N-dimethylformamide, it may have a certain solubility. Due to the interaction between the solvent and the solute molecules, such as hydrogen bonds and van der Waals forces, the solute can be dispersed in the solvent. In water, due to the relatively small number of hydrophilic groups in the molecular structure and the large number of hydrophobic parts, the solubility is very small.

In addition, the density of the compound is also one of its physical properties. The size of the density depends on the molecular weight and the degree of molecular packing compactness. Accurate determination of density is of great significance for its applications in chemical production, pharmaceutical preparation and other fields, and is related to the accuracy of material measurement, mixing ratio and other operations.

And its refractive index also characterizes its optical properties. Refractive index reflects the degree of refraction of light when passing through the substance, and is related to the order of molecular structure and electron cloud distribution, which can provide important information for identification and purity analysis.

N- {5-chloro-4- [ (4-chlorophenyl) (cyano) methyl] -2-methylphenyl} -2-hydroxy-3,5-diiodobenzamide What are the application fields?

N- {5-chloro-4- [ (4-chlorophenyl) (cyano) methyl] -2-methylphenyl} -2-hydroxy-3,5-diiodobenzamide is an organic compound with a wide range of application fields.

In the field of pharmaceutical research and development, such compounds containing specific substituents may have unique biological activities. The presence of halogen atoms and cyano groups can change the interaction between compounds and target molecules in vivo. For example, halogen atoms can affect the lipid solubility and electron cloud distribution of molecules, helping them to penetrate cell membranes and bind to specific receptors. It may exhibit potential anti-inflammatory and anti-tumor pharmacological activities by regulating specific biological signaling pathways in vivo.

In the field of pesticide creation, such compounds may have insecticidal and bactericidal effects. Their structures can interact with enzymes or receptors related to key physiological processes in insects or pathogens. For example, they can inhibit the synthesis of pathogen cell walls or interfere with the normal functions of insect nervous systems, thus achieving the prevention and control of pests and diseases, and providing assistance for agricultural safety production.

In the field of materials science, this compound may have emerged in the preparation of functional materials due to its special structure and properties. For example, it can be used as a basic unit for the construction of new photoelectric materials, and its intramolecular charge transfer properties can endow the materials with unique optical and electrical properties. It is expected to be applied to organic Light Emitting Diodes, solar cells and other fields to promote the progress and innovation of materials science.

What is the synthesis method of N- {5-chloro-4- [ (4-chlorophenyl) (cyano) methyl] -2-methylphenyl} -2-hydroxy-3,5-diiodobenzamide

To prepare N- {5-chloro-4- [ (4-chlorophenyl) (cyano) methyl] -2-methylphenyl} -2-hydroxy-3,5-diiodobenzamide, you can follow the following method.

First take the appropriate starting material, starting with 5-chloro-2-methylbenzoic acid. Convert it into the corresponding acid chloride, which can be obtained by co-thermal reaction with thionyl chloride and other reagents. The acid chloride has good activity and is convenient for subsequent reactions.

At the same time, an intermediate containing cyanide and chlorophenyl is prepared. Starting with 4-chlorophenylacetonitrile, under the catalysis of an appropriate base, a nucleophilic substitution reaction occurs with halogenated alkanes, and a suitable substituent is introduced to obtain a structural fragment of 4- [ (4-chlorophenyl) (cyano) methyl]. After

, the above-mentioned acid chloride-containing product and the intermediate containing 4- [ (4-chlorophenyl) (cyano) methyl] are carried out in a suitable organic solvent in the presence of a catalyst. Control the reaction temperature, time and other conditions to make the two condensate smoothly to form an amide bond.

Furthermore, the obtained amide product is halogenated. Using iodine as a halogenating reagent, in the presence of an appropriate oxidant such as hydrogen peroxide or other mild oxidants, the benzene ring is iodized at a specific location in a suitable solvent, thereby introducing the structure of 2-hydroxy-3,5-diiodine. The reaction process needs to be closely monitored to ensure that the iodization reaction occurs accurately at the desired location.

Finally, the reaction product is isolated and purified. Using column chromatography, recrystallization and other means to remove impurities, a pure N- {5-chloro-4- [ (4-chlorophenyl) (cyano) methyl] -2-methylphenyl} -2-hydroxy-3,5-diiodobenzamide product is obtained. During the operation, a suitable eluent or solvent should be carefully selected according to the properties of the product to achieve the best purification effect.

What is the safety of N- {5-chloro-4- [ (4-chlorophenyl) (cyano) methyl] -2-methylphenyl} -2-hydroxy-3,5-diiodobenzamide

N- {5 -chloro-4- [ (4 -chlorophenyl) (cyano) methyl] -2 -methylphenyl} -2 -hydroxy-3,5 -diiodobenzamide, this is a complex organic compound. Regarding its safety, it should be viewed in detail from multiple aspects.

First of all, the chemical structure of the compound contains chlorine, iodine, cyano and other functional groups. The halogen atom of chlorine and iodine may give the compound a certain chemical activity and stability, but it may also affect its toxicity. Cyanyl is a highly toxic functional group, a compound containing cyanide group, under specific conditions or releasing cyanide, which is highly toxic and can seriously threaten life.

The second is its use. If it is used for scientific research, the experimenter needs to strictly follow the operating procedures, because it may be potentially harmful. If it is industrial production, the waste containing this compound must be properly disposed of during the production process to prevent pollution of the environment.

Look at the environmental impact again. After this compound enters the environment, it may be difficult to degrade due to its complex structure. Accumulate in soil and water bodies, or endanger the ecosystem. It may have adverse effects on aquatic organisms, soil microorganisms, etc., and destroy the ecological balance.

In terms of human contact, skin contact, inhalation, or accidental ingestion are all risks. Skin contact or reactions such as allergies and irritation; inhalation of its dust or volatiles can damage the respiratory tract; after ingestion, or chemical reactions occur in the body, endangering health.

To know the safety of this compound, in-depth toxicological studies are needed, such as acute toxicity, chronic toxicity, teratogenicity, carcinogenesis, etc. Only in this way can the potential harm to the human body and the environment be fully evaluated, and appropriate protective and management measures can be taken to ensure the safety of personnel and environmental health.