N Acetyl 3 5 Diiodo L Tyrosine
Iodobenzene

N-acetyl-3-5-diiodo-l-tyrosine

Fengxi Chemical

Specifications

HS Code

558622

Chemical Formula C9H9I2NO4
Molar Mass 432.98 g/mol
Appearance White to off - white powder
Solubility In Water Poorly soluble
Melting Point 155 - 158 °C
Odor Odorless
Purity Typically high purity for pharmaceutical use
Chirality Has L - configuration (as L - tyrosine derivative)
Stability Stable under normal storage conditions
Uv Absorption Absorbs in the ultraviolet region
Chemical Formula C9H9I2NO4
Molar Mass 432.98 g/mol
Appearance White to off - white powder
Solubility Slightly soluble in water
Pka Approximately 2 - 3 (carboxyl group)
Melting Point 190 - 194 °C
Stability Stable under normal conditions, but light - sensitive
Chirality Exists in L - form (as it is related to L - tyrosine)
Odour Odourless
Main Function Intermediate in thyroid hormone synthesis
Chemical Formula C9H9I2NO4
Molar Mass 432.98 g/mol
Appearance White to off - white powder
Solubility In Water Poorly soluble
Solubility In Organic Solvents Soluble in some organic solvents like DMSO
Pka Value Around 2 - 3 (carboxyl group)
Melting Point 195 - 199 °C
Stability Stable under normal conditions, but sensitive to light and air
Isomeric Form Exists as L - isomer
Function Intermediate in thyroid hormone synthesis
Chemical Formula C9H9I2NO4
Molar Mass 432.98 g/mol
Appearance White to off - white powder
Solubility In Water Slightly soluble
Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO
Melting Point Approximately 195 - 197 °C
Pka Value Typically around 2 - 3 for the carboxylic acid group
Stability Stable under normal conditions, but sensitive to light and air over time
Isomerism Exists as an L - isomer (as specified in the name, L - tyrosine derivative)
Role In Biochemistry Intermediate in the synthesis of thyroid hormones
Packing & Storage
Packing 100g of N - acetyl - 3,5 - diiodo - L - tyrosine in a sealed, chemical - resistant container.
Storage N - acetyl - 3,5 - diiodo - L - tyrosine should be stored in a cool, dry place away from direct sunlight. Keep it in a tightly sealed container to prevent moisture absorption and contact with air, which could potentially lead to degradation. Store at a temperature range of 2 - 8°C if possible, as this helps maintain its chemical stability over time.
Shipping N - acetyl - 3,5 - diiodo - L - tyrosine is shipped in well - sealed containers. Special care is taken to prevent exposure to moisture and heat. Shipment follows all relevant chemical transport regulations to ensure safety during transit.
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N-acetyl-3-5-diiodo-l-tyrosine N-acetyl-3-5-diiodo-l-tyrosine N-acetyl-3-5-diiodo-l-tyrosine
General Information
Frequently Asked Questions
What are the main uses of N-acetyl-3,5-diiodo-L-tyrosine?
N-acetyl-3,5-diiodo-L-tyrosine (N-acetyl-3,5-diiodine-L-tyrosine) is widely used in the field of medicine and chemical industry.
In medicine, one of them is the key intermediate of thyroxine synthesis. Thyroxine plays an important role in human metabolism, growth and development and other physiological processes. This compound can help form thyroxine through a series of biochemical reactions and maintain normal physiological functions of the human body. If thyroxine synthesis is bad, diseases such as hyperthyroidism or hypothyroidism will occur. Therefore, N-acetyl-3,5-diiodo-L-tyrosine is an indispensable raw material in the development and manufacture of thyroid-related drugs.
Second, it is also useful in diagnostic reagents. Due to its special chemical structure and properties, it can participate in diagnostic technologies such as immunoanalysis. By marking or participating in specific reactions, it can accurately detect relevant biomarkers in the human body, assist in early diagnosis and disease monitoring, and provide an important basis for doctors to treat diseases.
In the chemical industry, it can be used as an important building block for organic synthesis. Due to its specific functional groups and iodine atoms, it can introduce other groups through chemical reactions to build more complex organic molecular structures, which can be used to develop new materials, fine chemicals, etc., to expand the category and performance of chemical products, and to contribute significantly to the development of chemical innovation.
What are the chemical properties of N-acetyl-3,5-diiodo-L-tyrosine?
N-acetyl-3,5-diiodo-L-tyrosine (N-acetyl-3,5-diiodol-L-tyrosine) is an organic compound with unique chemical properties.
This compound is acidic because it contains a carboxyl group (-COOH). The hydrogen in the carboxyl group can be partially ionized, and it exhibits acidic properties under suitable conditions. It can neutralize and react with bases to generate corresponding salts and water.
In terms of solubility, its solubility in water is limited. Because its molecular structure contains hydrophobic groups, its solubility may be better in some organic solvents such as ethanol and acetone. The force between the organic solvent and the compound is appropriate, which can help it disperse and dissolve.
In terms of stability, it is relatively stable, but it can change under specific conditions. For example, in a strong acid or alkali environment, its amide bond (-CONH -) may be hydrolyzed, and amide bond breakage may cause molecular structure changes; under high temperature conditions, it may also trigger reactions such as intramolecular rearrangement or decomposition.
Optically active, due to its chiral center (L-configuration), it is optically active and can rotate polarized light. This property is of great significance in the field of asymmetric synthesis and drug development, and different configurations have a significant impact on biological activity.
It also has certain chemical reactivity, and phenolic hydroxyl (-OH) can undergo substitution reactions, such as reacting with acyl halide or acid anhydride to form ester compounds, providing a way for the construction of new compounds in organic synthesis.
What is the production method of N-acetyl-3,5-diiodo-L-tyrosine?
N-acetyl-3,5-diiodo-L-tyrosine is an organic compound. The preparation method is often based on the chemical modification of L-tyrosine.
In the past, this compound was mostly prepared with L-tyrosine as the starting material. First take an appropriate amount of L-tyrosine and place it in a specific reaction vessel. Then, under suitable reaction conditions, add an acetylation reagent, such as acetic anhydride. This acetylation step requires strict temperature control and reaction time to allow the amino group of L-tyrosine to be acetylated smoothly to generate N-acetyl-L-tyrosine.
Subsequently, N-acetyl-L-tyrosine is transferred to the reaction system containing iodine reagents. Commonly used iodine reagents include iodine elemental elements and appropriate oxidant combinations, such as iodine and hydrogen peroxide. During this iodization reaction, the pH and temperature of the environment are key factors. Under suitable conditions, iodine atoms can be selectively added to the 3rd and 5th positions of the N-acetyl-L-tyrosine benzene ring to obtain N-acetyl-3,5-diiodo-L-tyrosine.
There are also improved methods, such as the use of phase transfer catalysis, to improve the reaction efficiency and reduce the occurrence of side reactions. By finely adjusting the reaction parameters and optimizing the reaction process, the purity and yield of the product can reach the ideal level to meet the needs of N-acetyl-3,5-diiodo-L-tyrosine in different fields.
What is the price range of N-acetyl-3,5-diiodo-L-tyrosine in the market?
I think this "N - acetyl - 3,5 - diiodo - L - tyrosine" is a chemical substance. However, the price range between the markets is difficult to determine. The price is affected by many factors.
First, quality is essential. If the quality is high, the purification is excellent, and the impurities are rare, the price will be high; if the quality is slightly inferior, the impurity is more, and the price will be lower.
Second, the supply and demand situation is also serious. If the market is in demand, and the supply is limited, the price may rise; if the supply exceeds the demand, the price will fall.
Third, the manufacturing cost is different. The price of raw materials, the simplicity of the production process, the amount of energy consumption, etc., all affect the cost, which in turn affects the selling price.
Fourth, the place of sale and the channel are different, and the price is also different. In prosperous commercial ports, due to rent, transportation and other fees, the price may be high; in remote places, the price may be slightly lower. And direct sales and multi-layer agents, the price is also different.
Overall, in order to determine the price, it is necessary to carefully consider the quality, supply and demand, cost, and sales. Without knowing all these details today, it is difficult to determine the price range. Although it is difficult to specify the specific price, the price can be inferred or fluctuated in a wide range due to the above reasons.
What are the Quality Standards for N-acetyl-3,5-diodol-L-tyrosine?
N-acetyl-3,5-diiodo-L-tyrosine is also an organic compound. Its Quality Standard is extremely important, related to the purity, characteristics and uses of this substance.
In terms of purity, high purity of N-acetyl-3,5-diiodo-L-tyrosine is quite critical. Usually its purity is required to reach a very high level, and the impurity content needs to be strictly controlled in a very low range. If there are many impurities, it will affect its application effect in medicine, biochemical research and other fields. It may cause deviations in experimental results, or cause adverse reactions when the drug is used.
Its appearance is also one of the Quality Standards. Under normal circumstances, it should present a specific physical state, such as powder, uniform particle size, pure color, and no obvious heterochromia or foreign matter doping.
Melting point is also an important indicator. A specific melting point range can verify its structural stability and purity. If the melting point deviates from the established range, it may suggest that the molecular structure has changed or there is impurity interference, which affects its quality.
In addition, the stability of chemical properties is indispensable. Under conventional storage conditions, it should be able to maintain its chemical structure and properties unchanged for a long time to ensure that it can play its due role in subsequent use.
In the quality inspection process, sophisticated analytical instruments and scientific testing methods are required. For example, high performance liquid chromatography is used to accurately determine purity, and melting point is accurately measured by melting point meter. Only by strictly following various Quality Standards can we ensure that N-acetyl-3,5-diiodo-L-tyrosine can be properly used in various fields and play its due value.