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What is the chemical structure of N-acetyl-3,5-diiodo-l-tyrosine Ethyl Ester?
N-acetyl-3,5-diiodo-L-tyrosine Ethyl Ester is an organic compound. The analysis of its chemical structure requires detailed investigation of the composition of each part.
"N-acetyl" refers to the acetyl group, which is a common functional group formed by the connection of carbonyl (C = O) and methyl (CH
"3,5-diiodo"), often shown as -COCH, which can affect the properties and reactivity of molecules in compounds.
"3,5-diiodo" table introduces iodine atoms at specific positions (3rd and 5th positions). The iodine atom is relatively heavy relative to the atom, and its introduction will significantly change the physical and chemical properties of the compound, such as increasing the polarity of the molecule and affecting the spatial structure.
"L-tyrosine" is L-tyrosine, which is a naturally occurring amino acid with an amino group (-NH ²), a carboxyl group (-COOH) and a specific side chain structure. In this compound, tyrosine is an important part of the main structure.
"Ethyl Ester" is ethyl ester, indicating that the carboxyl group in this compound reacts with ethanol to esterify, forming an ester group structure of -COOCH -2 CH 🥰. The existence of ester groups also has an important impact on the solubility and stability of the compound.
In general, the chemical structure of N-acetyl-3,5-diiodo-L-tyrosine Ethyl Ester is composed of 3,5-diiodo-L-tyrosine modified by acetyl group and ethyl ester group through esterification reaction. This structure endows the compound with unique physical and chemical properties, which may have specific application and research value in the fields of organic synthesis, medicinal chemistry, etc.
What are the main uses of N-acetyl-3,5-diodol-l-tyrosine Ethyl Ester?
N-Acetyl-3,5-diiodol-L-tyrosine ethyl ester is widely used. In the field of medicine, it is often a key intermediate in thyroid hormone synthesis. Thyroid hormones play a crucial role in regulating human metabolism, growth and development, and the function of the nervous system. Through the rational use of this compound, it can help synthesize thyroid hormone drugs for the treatment of related diseases such as hypothyroidism, correct human thyroid hormone levels, and maintain the normal operation of the body's physiological functions.
In the field of organic synthesis, as an organic compound with a unique structure, it provides an effective starting material for the construction of many complex organic molecules. With its acetyl group, iodine atom and tyrosine ethyl ester structure, chemists can use various organic reactions to modify and derive its structure, thereby preparing a series of new organic compounds with specific biological activities or physicochemical properties, providing a key material basis for new drug development, materials science and many other fields.
In addition, in scientific research, it is often used as an important tool to study the biosynthetic mechanism of thyroid hormones, drug targets and metabolic pathways. Through in-depth study of its transformation and reaction mechanism under different reaction conditions, researchers can more thoroughly understand the physiological and pathological processes related to thyroid hormones, and then provide a solid theoretical basis and experimental support for the diagnosis, treatment and prevention strategies of related diseases.
What is the synthesis method of N-acetyl-3,5-diiodo-l-tyrosine Ethyl Ester?
The method of synthesizing N-acetyl-3,5-diiodo-l-tyrosine Ethyl Ester (N-acetyl-3,5-diiodo-L-tyrosine ethyl ester) is described in ancient books. First take L-tyrosine, dissolve it in an appropriate amount of dilute alkali solution, such as sodium hydroxide solution, and dissolve it into a homogeneous state.
Then, slowly add acetylating reagents, such as acetic anhydride, to the reaction system. When adding dropwise, the temperature should be controlled moderately to avoid side reactions caused by excessive temperature. After acetylation is completed, acid can be added to adjust the pH of the system to acidic, so that the acetylation product is precipitated, separated, washed, and dried to obtain N-acetyl-L-tyrosine.
Second, N-acetyl-L-tyrosine is redissolved in a suitable solvent, such as glacial acetic acid. In this solution, a small amount of iodine source, such as a mixture of iodine elemental substance and potassium iodide, is added in batches, and temperature control is also required. This step is designed to precisely iodize the 3rd and 5th positions of the benzene ring. After the reaction is completed, N-acetyl-3,5-diiodine-L-tyrosine is obtained through a series of post-treatments, such as filtration and recrystallization.
At the end, take N-acetyl-3,5-diiodine-L-tyrosine, and place it in a reaction vessel with ethanol and an appropriate amount of catalyst, such as concentrated sulfuric acid. Heat reflux to cause esterification. At the end of the reaction, through distillation, extraction, drying and other steps, pure N-acetyl-3,5-diiodo-l-tyrosine Ethyl Ester product can be obtained. This synthesis method involves complicated steps, but it requires careful steps to obtain satisfactory yield and purity.
What is the market price range for N-acetyl-3,5-diiodo-l-tyrosine Ethyl Ester?
I do not know the market price range of N-acetyl-3,5-diiodo-l-tyrosine Ethyl Ester. The price of this compound may vary depending on the use, purity, supply and demand. In the era of "Tiangong Kaiwu", there was no such fine chemical, so it is difficult to state its price in the book. At present, if you ask for its price, you can ask it on the chemical trading platform and reagent supplier. Or the price varies due to scientific research and industrial use. The price of high purity may be high, and the price of common purity may be slightly flat. However, due to the changeable market, it is difficult to determine the price range. To get an accurate price, when you go to the relevant platform or merchant in person and ask their information, you can know its approximate price range.
What are the precautions for N-acetyl-3,5-diiodo-l-tyrosine Ethyl Ester during storage and transportation?
N - acetyl - 3,5 - diiodo - l - tyrosine Ethyl Ester is a special chemical substance. During storage and transportation, many matters need to be paid careful attention.
First words storage, this substance should be placed in a cool, dry and well ventilated place. Avoid high temperature and humidity. High temperature can cause its chemical properties to change, and moisture can also cause it to deteriorate. It should be stored in a sealed container to prevent excessive contact with air, so as to avoid chemical reactions such as oxidation and damage to its quality.
As for transportation, be sure to ensure that the packaging is stable and tight. Choose suitable packaging materials that can withstand certain vibrations and collisions to avoid material leakage caused by container damage during transportation. The transportation environment should also be temperature-controlled and moisture-proof, and a suitable temperature and humidity range should be maintained according to its chemical characteristics. Transportation personnel need to be familiar with its characteristics and emergency response methods. In case of emergencies such as leakage, they can be properly handled quickly to prevent the expansion of hazards.
In short, the storage and transportation of N-acetyl-3,5-diiodo-l-tyrosine Ethyl Ester must strictly abide by relevant norms and requirements, and carefully control the environment, packaging, personnel and other aspects to ensure its quality and safety.