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What is the chemical structure of N, N '-bis (1,3-dihydroxypropyl-2-yl) -5- {[ (2S) -2-hydroxypropionyl] amino} -2,4,6-triiodobenzene-1,3-diformamide?
The chemical structure of N, N '-bis (1,3-dimethyl-2-yl) -5- {[ (2S) -2-methylpyrrolidyl] amino} -2,4,6-tribromo-1,3-dimethylbenzamide is an interesting topic in the field of organic chemistry.
The complex and delicate structure of this compound, in which N, N' -bis (1,3-dimethyl-2-yl) moiety is like a building block, establishing the basic structure of the molecule. The 1,3-dimethyl-2-group gives the molecule a specific spatial configuration and electronic properties. The fragment of 5- {[ (2S) -2 -methylpyrrolidine] amino} is like a smart arm, which is cleverly connected to the main structure. The stereo configuration of (2S) -2 -methylpyrrolidine, that is, the S configuration, has a profound impact on the physical and chemical properties of the molecule as a whole, and its chiral characteristics may make the compound exhibit unique performance in specific reactions or biological activities.
Furthermore, the 2,4,6 -tribromo part is like three sharp blades, and the introduction of bromine atoms greatly changes the electron cloud distribution of the molecule, enhancing its electrophilicity and reactivity. Bromine atoms also play a significant role in the melting point, boiling point and solubility of compounds due to their electronegativity and large size, or affect the intermolecular forces. 1,3-dimethylbenzamide is the core skeleton of the molecule, and the conjugation system of benzene ring endows the molecule with certain stability and electron delocalization ability. Amide groups have unique chemical activity and hydrogen bond formation ability, which is of great significance for intermolecular interactions and biological activity.
In summary, the chemical structure of N, N '-bis (1,3-dimethyl-2-yl) -5 - {[ (2S) -2 -methylpyrrolidine] amino} -2, 4, 6 -tribromo-1,3 -dimethylbenzamide is synergistic, which jointly shapes the unique chemical and physical properties of the compound, laying the foundation for its application in organic synthesis, drug development and other fields.
What are the main uses of N, N '-bis (1,3-dihydroxypropyl-2-yl) -5- {[ (2S) -2-hydroxypropionyl] amino} -2,4,6-triiodobenzene-1,3-diformamide?
N, N '-bis (1,3-dimethyl-2-butyl) -5- {[ (2S) -2-methylbutyl] amino} -2,4,6-tribromo-1,3-dimethylbenzamide, which is widely used. In the field of medicine, it can be used as an intermediate for the treatment of specific diseases. With its unique chemical structure, it participates in the drug synthesis process, laying the foundation for drug activity and efficacy; in the field of materials science, it can be used as a functional auxiliary to integrate polymer materials, improve the properties of materials such as UV resistance and oxidation resistance, and then expand the application scenarios and service life of materials; in agriculture, it can be used as a pesticide synergist to enhance the control effect of pesticides on pests and diseases, reduce the amount of pesticides applied, and reduce the impact on the environment. Such diverse uses make it valuable in a wide range of fields, including chemicals, medicine, materials, and agriculture, promoting technological innovation and development in related industries.
What are the pharmacological effects of N, N '-bis (1,3-dihydroxypropyl-2-yl) -5- {[ (2S) -2-hydroxypropionyl] amino} -2,4,6-triiodobenzene-1,3-diformamide?
N, N '-bis (1,3-difuranoacrylic-2-yl) -5 - {[ (2S) -2 -furanoacrylamino] formyl} -2,4,6 -tribromo-1,3-dimethylbenzamide, this drug has unique pharmacological effects.
Looking at its structure, multiple furan groups, bromine atoms and methyl groups are cleverly connected to give it specific activity. In terms of pharmacological mechanism, the furanyl structure of the compound may affect its interaction with biological targets, providing a suitable spatial configuration and electronic effect for the binding of drugs to specific receptors or enzymes, so that they can precisely act on the corresponding targets.
Its benzamide part is also very important. The presence of amide bonds may affect the stability, lipophilicity and hydrogen bond interaction with the target of the drug molecule, thereby regulating the activity and selectivity of the drug. The introduction of multiple bromine atoms may change the electron cloud distribution of the molecule, enhance its interaction with the target, and also have a certain impact on the lipophilicity and metabolic stability of the drug.
This drug may be able to regulate physiological processes such as signal transduction pathways and enzyme activities in cells by virtue of the above structural characteristics, and then exert the effect of treating diseases, or exhibit unique pharmacological activities in anti-tumor, anti-inflammatory and other fields.
What are the adverse reactions of N, N '-bis (1,3-dihydroxypropyl-2-yl) -5- {[ (2S) -2-hydroxypropionyl] amino} -2,4,6-triiodobenzene-1,3-diformamide?
In "Tiangong Kaizhi", N, N '-bis (1,3-dimethyl-2-butyl) -5- {[ (2S) -2-methylbutyryl] amino} -2, 4,6-tribromo-1,3-dimethylbenzamide is not sensitive to the reaction, there are the following numbers.
In this product, the effect of spatial steric hindrance is significant. In its molecular structure, 1,3-dimethyl-2-butyl and 2-methylbutyryl and other substituents occupy a large space. In this way, the difficulty of the reactant approaching the reaction check point increases, and the reactivity decreases. For example, in the nucleophilic substitution reaction, it is difficult for the nucleophilic reagent to get close to the substituted check point on the benzene ring, which hinders the reaction.
The electronic effect is also key. The 2,4,6-tribromo substitution on the benzene ring has an electron-absorbing induction effect on the bromine atom, which reduces the electron cloud density of the benzene ring. While the substituents connected to 1,3-dimethyl and N, N 'have electron-inducing effects and superconjugation effects, in general, the influence of electron-absorbing bromine atoms is dominant. In the electrophilic substitution reaction, the binding force between the electrophilic reagent and the benzene ring becomes weak, and adverse reactions occur.
Furthermore, the molecular stability is quite high. In its structure, each atom is connected through a covalent bond to form The N, N 'linked groups interact with the benzene ring conjugated system to strengthen molecular stability. From the energy point of view, the reaction needs to overcome a high energy barrier, resulting in the emergence of allergic reactions.
The allergic reaction of this compound is due to the combined effect of steric hindrance, electronic effect and molecular stability, which hinders the progress of common chemical reactions.
N, N '-bis (1,3-dihydroxypropyl-2-yl) -5- {[ (2S) -2-hydroxypropionyl] amino} -2,4,6-triiodobenzene-1,3-diformamide What are the precautions when using?
N, N '-bis (1,3-difuranyl-2-yl) -5- {[ (2S) -2-furanylmethylamino] carbonyl} -2,4,6-tribromo-1,3-dimethylbenzamide When using this material, pay attention to the following:
First, because its structure contains bromine atoms, in some scenarios, bromide may cause specific environmental effects and health risks. When using, pay attention to the protection of the environment, avoid random discharge, and prevent pollution to the surrounding ecology; when operating, wear appropriate protective equipment, such as masks and gloves, to prevent bromine from harming the human body through breathing, skin contact, etc. If accidentally exposed, rinse with plenty of water immediately and seek medical attention in time.
Second, the furan-based structure has potential photosensitivity. Avoid direct exposure to strong light during use, and store in a cool and dark place, otherwise it may cause chemical reactions due to light, causing structural changes and performance changes, which will affect the use effect.
Third, as a complex organic compound, its chemical properties are active. When using, be sure to strictly follow the operating procedures to avoid contact with strong oxidants, strong acids, strong bases and other improper substances to prevent violent reactions, such as combustion, explosion and other dangerous conditions. Before reacting or using, be fully aware of its chemical properties and possible reactions, and develop a complete safety plan.
Fourth, in view of the complexity of the compound structure, different batches of products may vary in purity, impurity types and content. Before use, the product needs to be strictly tested to ensure that the purity, impurities and other indicators meet the requirements of use, so as to avoid impurities affecting the reaction process or product quality.