N,N'-Bis(2,3-Dihydroxypropyl)-2,4,6-Triiodo-5-[(Methoxyacetyl)Amino]-N-Methyl-1,3-Benzenedicarboxamide

This is an organic compound with the Chinese name N, N '-bis (2,3-dihydroxypropyl) -2,4,6-triiodo- 5- [ (methoxyacetyl) amino] -N-methyl-1,3-benzodiformamide. Its chemical structure is as follows:
The core of the molecule is a benzene ring, which is a distinctive feature of aromatic compounds. On the benzene ring, one formamide group is connected to the methyl group. The nitrogen atom of one formamide group is connected to the methyl group, and the nitrogen atom of the other formamide group is connected to two 2,3-dihydroxypropyl groups, showing a unique branching structure.
Looking at the benzene ring again, the 2,4,6 positions are occupied by iodine atoms, and the introduction of iodine atoms greatly affects the physical and chemical properties of the compound. The 5 position of the benzene ring is connected to the [ (methoxyacetyl) amino group], the methoxy group in this structure is connected to the acetyl group, and the acetyl group is connected to the amino group, which is then connected to the benzene ring.
In this way, the structure of each part is orderly combined to form N, N '-bis (2,3-dihydroxypropyl) -2,4,6-triiodine-5- [ (methoxyacetyl) amino] -N-methyl-1,3-benzodiformamide unique chemical structure.

N, N '-bis (2,3-dihydroxypropyl) -2,4,6-triiodine-5- [ (methoxyacetyl) amino] -N-methyl-1,3-benzodiformamide, this is an organic compound. It has a wide range of uses and is often used as a contrast agent in the field of medicine. In X-ray, CT and other imaging examinations, it can help to clearly develop specific parts of the human body because of its iodine-containing elements, high atomic number of iodine, and strong absorption of X-rays.
In medical diagnosis, by introducing this compound into the human body, the tissue or organ to be observed can be significantly compared with the surrounding tissue in the image, such as for angiography, which can clearly show the shape, direction and presence of blood vessels. It helps doctors accurately diagnose vascular blockage, stenosis and other diseases; in urography, it can understand the structure and function of the urinary system, which is of great significance for the diagnosis of urinary system stones, tumors and other diseases.
Furthermore, in the field of scientific research, it may serve as a tracer, with its special structure and properties, to track the metabolism and distribution of specific substances in organisms, and help researchers to deeply explore the life process and disease mechanism.

This drug is called N, N '-bis (2,3-dihydroxypropyl) -2,4,6-triiodine-5- [ (methoxyacetyl) amino] -N-methyl-1,3-benzodiformamide. In terms of its safety, this drug is usually safe when used reasonably.
It is used in specific medical situations and has been clinically administered by many physicians. It can meet the needs of the disease. However, the nature of the drug varies, and people have different endowments, and their reactions to the drug are also different. Some people use it, or there is no obvious discomfort, while some people may experience mild discomfort, such as local swelling and occasional redness of the skin. This is due to individual differences and is not the norm of medicine.
When taking medicine, a doctor must carefully review the patient's physical condition and the severity of the disease, weigh the pros and cons, and determine the dosage and method of medication to ensure that the medicine reaches the disease without damaging the righteousness. During the medication period, the patient's reaction should be closely monitored. If there is any abnormality, it will be easier to treat it in time to ensure the safety of the medication. In short, this medicine can be used by the right person, at the right time, and in the right way. Its safety can be guaranteed and it can be helpful for the treatment of diseases.

To prepare N% 2CN% 27 - bis (2,3 - dihydroxypropyl) - 2,4,6 - triiodo- 5 - [ (methoxyacetyl) amino] - N - methyl - 1,3 - benzodiformamide, the method is as follows:
Take an appropriate amount of 2,4,6 - triiodo- 5 - amino - N - methyl - 1,3 - benzodiformamide and place it in a clean reactor. Then slowly add methoxyacetyl chloride. This process needs to be carefully controlled to prevent side reactions. The molar ratio of methoxyacetyl chloride to 2,4,6-triiodine-5-amino-N-methyl-1,3-phthalamide should be carefully prepared, usually 1.2-1.5:1.
After the reaction proceeds smoothly for a period of time, an appropriate amount of acid binding agent, such as triethylamine, can be added to help the smooth progress of the reaction and remove the hydrogen chloride generated by the reaction. At this stage, it is still necessary to pay close attention to the reaction temperature and the pH of the system.
Then, the product obtained by the reaction is separated and purified, and the impurities are extracted multiple times with an organic solvent to remove impurities. The method of recrystallization is carried out, and a suitable solvent is selected, such as ethanol-water mixed solvent, to further improve the purity of the product.
After the recrystallized solid is dried, a relatively pure 5- [ (methoxyacetyl) amino] -2,4,6-triiodo- N-methyl-1,3-benzodiformamide can be obtained.
Mix this intermediate product with epichlorohydrin in a certain proportion, and add an appropriate amount of basic catalyst, such as sodium hydroxide. Control the reaction temperature to a specific range and the number of reactions. In this process, the ring-opening reaction of epichlorohydrin occurs with the nucleophilic substitution of the amino group of the intermediate product, and the target product N% 2CN% 27 -bis (2,3-dihydroxypropyl) -2,4,6 -triiodo- 5 - [ (methoxyacetyl) amino] -N -methyl-1,3-benzodiformamide is gradually formed.
The final product can be obtained with good quality N% 2CN% 27 -bis (2,3 -dihydroxypropyl) -2,4,6 -triiodo- 5 - [ (methoxyacetyl) amino] -N -methyl-1,3 -benzodiformamide after re-separation, purification, drying and other steps. The whole preparation process, the conditions of each step are controlled and the fineness of the operation is related to the purity and yield of the product, which should not be ignored.

Ah, this is a chemical substance, named N% 2CN% 27 - bis (2,3 - dihydroxypropyl) - 2,4,6 - triiodine - 5 - [ (methoxyacetyl) amino] - N - methyl - 1,3 - benzodiformamide. Compared with other similar products, it has many advantages.
First, this product is unique in hydrophilicity. Its molecular structure is rich in many hydroxyl groups, making it hydrophilic and more soluble in water. This property is particularly important in the field of pharmaceutical preparations. Because it is easily soluble, it can be dispersed and absorbed more quickly in the body, so that the drug effect can be exerted faster, and the curative effect is more significant.
Second, in terms of stability, it also has outstanding performance. The unique molecular structure gives it good chemical stability. Under different environmental conditions, it can maintain its own structural stability and is not easy to decompose and deteriorate. In this way, during storage and transportation, it can be stored for a long time without too harsh conditions, and the quality is guaranteed reliably, which greatly reduces the cost.
Third, its targeting advantage should not be underestimated. The structure of the substance has been carefully designed to show strong targeting to specific tissues or cells. In the treatment of diseases, it can accurately reach the lesion site, concentrate on the effect, reduce the damage to other normal tissues and cells, greatly improve the therapeutic effect, and reduce the side effects of drugs, which is undoubtedly a great blessing for patients.
Fourth, from the perspective of safety, after a large number of experiments and verification, this substance is quite safe. Within the acceptable dose range of the human body, it will not cause serious adverse reactions and pose a minimal threat to human health. This makes it more feasible and valuable in clinical application.