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What is N, N '-bis (2,3-dihydroxypropyl) -5- (2- (hydroxymethyl) hydroxyacrylamide) -2,4,6-triiodine-N, N' -dimethylisophthalamide?
This is a rather complex organic compound. In its name, "N, N '-bis (2,3-difuranoethyl) -5- (2- (furanomethyl) furanoethylcarbazolyl) -2,4,6-tribromo-N, N' -dimethyl isophthalimide". The structure of this compound contains several specific groups.
From the perspective of group composition, the furan group is a five-membered heterocyclic structure containing one oxygen atom and has aromatic properties. There are multiple furyl groups in the compound, such as 2,3-difuranoethyl, and the existence of such groups may have a significant impact on the electron cloud distribution, spatial structure and physicochemical properties of the compound. 5 - (2 - (furanmethyl) furanoethylcarbazolyl) moiety, carbazole is a nitrogen-containing fused cyclic aromatic hydrocarbon, and its conjugate structure gives the compound unique optical and electrical properties. 2,4,6-tribromo moiety, the bromine atom has a large electronegativity, and after introduction or enhancement of molecular polarity, it affects its solubility, stability and reactivity. N, N '-dimethyl isophthalimide, isophthalimide is a cyclic imide structure, and the substitution of dimethyl also alters the steric resistance and electronic effects of the molecule.
This compound may have potential applications in the field of materials science due to its complex structure. For example, its unique conjugate structure and multi-group properties may make it suitable for organic optoelectronic materials, such as organic Light Emitting Diode (OLED), organic solar cells, etc., by adjusting the molecular structure to optimize optoelectronic properties. In organic synthesis chemistry, as a key intermediate, it can be used to construct more complex compound structures due to its diverse reaction check points.
What are the uses of N, N '-bis (2,3-dihydroxypropyl) -5- (2- (hydroxymethyl) hydroxyacrylamide) -2,4,6-triiodine-N, N' -dimethylisophthalamide?
N, N '-bis (2,3-difluorobenzyl) -5 - (2- (fluoromethyl) furanylfuranoyl) -2, 4,6-tribromo-N, N' -dimethyl isophthalamide, this compound has important uses in many fields.
In the field of pharmaceutical research and development, the specific group combination in its structure gives it unique biological activity. The introduction of fluorine atoms can change the lipid solubility, stability and interaction with biological targets of the compound. For example, by precisely regulating the binding mode to specific receptors or enzymes, it is expected to develop new therapeutic drugs for certain diseases, such as in the development of anti-tumor drugs, which can interfere with the key signaling pathways of tumor cells and hinder the growth and proliferation of tumor cells.
In the field of materials science, this compound can participate in the preparation of materials with special properties due to its special structure. For example, in the field of organic optoelectronic materials, its unique molecular structure can affect the electronic transport and optical properties of materials, or it can be used to fabricate new organic Light Emitting Diode (OLED) materials, improve the luminous efficiency and stability, and then promote the development of display technology.
In the field of agriculture, given that its structure may have certain biological activities, it can be used as a potential pesticide ingredient. It can develop efficient, low-toxic and environmentally friendly pesticide products by virtue of its mechanism of action against specific pests or pathogens, effectively control crop diseases and insect pests, and ensure food yield and quality.
With its unique structure, this compound shows broad application potential in many fields such as medicine, materials, agriculture, etc. With the deepening of research, it is expected to bring innovative breakthroughs in various fields.
What are the side effects of N, N '-bis (2,3-dihydroxypropyl) -5- (2- (hydroxymethyl) hydroxyacrylamide) -2,4,6-triiodine-N, N' -dimethylisophthalamide?
N, N '-bis (2,3-difluoropropyl) -5- (2- (fluoromethyl) fluoropropynyl bromobenzoyl) -2,4,6-tribromo-N, N' -dimethyl isophthalamide, which is a class of organic compounds with a specific structure. Looking at the application scenarios of many substances involved in "Tiangong Kaiji", although this substance is not directly mentioned in the book, it is deduced from many aspects such as chemical pharmacology that such organic compounds may have multiple effects.
In the field of material synthesis, the structure contains special groups of fluorine and bromine. The introduction of fluorine atoms can often significantly change the physical and chemical properties of materials, such as enhancing the stability, chemical inertness and hydrophobicity of materials. The presence of bromine atoms may endow materials with specific reactivity, or can be used to prepare high-value functional materials, or participate in more complex organic synthesis reactions as intermediates, thereby constructing new materials with unique properties.
In the field of biomedicine, such compounds may have potential biological activities. Fluorinated organic compounds are common in drug development. Due to their special electronic effects and fat solubility, they can affect the interaction between drugs and biological targets and improve the efficacy and selectivity of drugs. Bromine atoms may also affect the biological activity of compounds, or affect the binding mode of biomacromolecules by adjusting the electron cloud distribution of molecules, so the compound may be used as a lead compound to develop new drugs and fight specific diseases.
In the field of flame retardancy, bromine is a common flame retardant element. This compound contains bromine. When heated or burned, bromine atoms can participate in a series of chemical reactions, release halogenated hydrogen gas, dilute the concentration of flammable gases, and capture free radicals generated in combustion reactions, thereby inhibiting combustion chain reactions and exerting flame retardant effects. It can be used to prepare flame retardant materials and ensure fire safety in many places.
What is the preparation method of N, N '-bis (2,3-dihydroxypropyl) -5- (2- (hydroxymethyl) hydroxyacrylamide) -2,4,6-triiodine-N, N' -dimethyl isophthalamide?
To prepare N, N '-bis (2,3-difluorobenzyl) -5- (2- (fluoromethyl) furanyl) furanylpyridinone-N, N' -dimethyl isophthalamide, the method is as follows:
First take an appropriate amount of 2,3-difluorobenzyl amine, place it in a clean reaction vessel, cool it at low temperature, slowly add a solution containing 5- (2- (fluoromethyl) furanyl) furanylpyridinone acid chloride, stir at the same time, maintain a certain temperature, so that the two can fully react. This reaction process requires constant attention to temperature changes and reaction phenomena to ensure the smooth progress of the reaction. After the reaction is completed, the organic phase is extracted with an appropriate organic solvent, and the organic phase is collected. It is washed with water and dried in sequence to remove impurities.
Another dimethyl isophthalic acid is taken and put into the reaction kettle. An appropriate amount of dehydrating agent and catalyst are added, and the temperature is raised to a certain extent, so that it undergoes a dehydration reaction to generate dimethyl isophthalic anhydride. After the reaction is completed, it is cooled, and the above-mentioned treated product containing 5- (2- (fluoromethyl) furyl) furyl pyridinone-difluorobenzyl amine is added to it, and the reaction is heated up again to make the two amide. This process also requires precise control of temperature and reaction time to ensure complete reaction.
When the amidation reaction is completed, the reaction mixture is cooled, poured into an appropriate amount of precipitant, and the product is precipitated. Filtered, the obtained solid is washed several times with an organic solvent to remove residual impurities, and then dried in vacuum to obtain pure N, N '-bis (2,3-difluorobenzyl) -5- (2- (fluoromethyl) furyl) furanylpyridinone-N, N' -dimethyl isophthalamide. During the whole preparation process, it is crucial to control the purity of the raw material, the control of the reaction conditions, and the connection between the steps. A slight difference may affect the yield and purity of the product.
What are the precautions for N, N '-bis (2,3-dihydroxypropyl) -5- (2- (hydroxymethyl) hydroxyacrylamide) -2,4,6-triiodine-N, N' -dimethylisophthalamide?
N, N '-bis (2,3 -difluorobenzyl) -5- (2- (fluoromethyl) furanylfuranamido) -2, 4,6 -tribromo-N, N' -dimethyl isophthalamide This compound is a product in the field of organic synthesis, and there are indeed many key considerations to be clarified when preparing and using it.
First, it is related to the reaction conditions. The synthesis of this compound involves many complex organic reactions, such as nucleophilic substitution, condensation, etc. Each step of the reaction requires strict requirements on temperature, pH, and reaction time. Like nucleophilic substitution, if the temperature is too high or side reactions occur frequently, the purity of the product is greatly affected; if the temperature is too low, the reaction is slow and the efficiency is low. The control of pH is also critical. The peracid or peralkali environment may change the structure of the reaction substrate or intermediate, hindering the forward progress of the reaction. Therefore, precise regulation of the reaction conditions can ensure that the reaction proceeds efficiently according to the expected path and improve the yield and purity of the product.
Second, the purity of the raw material is very important. The purity of the raw materials used in the synthesis, such as 2,3-difluorobenzyl related reagents, fluorine-containing methylfuran derivatives, etc., directly affects the quality of the product. The raw material has many impurities, which will participate in side reactions in the reaction, not only consume the raw material, but also generate complex impurities, which will cause great difficulty in the separation and purification of the product. Therefore, the raw material needs to be strictly purified before use, and its high purity is ensured by means of recrystallization, distillation, column chromatography
Third, the separation and purification are complicated. The product synthesis is completed, and the system is often mixed with unreacted raw materials, by-products and catalyst residues. Due to the similar physical and chemical properties of the target product and impurities, the separation and purification are challenging. Methods such as column chromatography, recrystallization, and preparatory liquid chromatography are commonly used. Column chromatography requires careful selection of eluents and stationary phases, and separation is achieved according to the polarity difference between the product and the impurity; recrystallization requires selection of suitable solvents, so that the solubility of the product varies significantly at different temperatures, so that the pure product can be precipitated.
Fourth, safety issues cannot be ignored. Some reagents involved in the synthesis may be toxic, corrosive, or flammable and explosive. For example, some fluorinated compounds are highly toxic, and the operation must be carried out in a well-ventilated environment. Wear protective equipment to avoid inhalation or contact with skin and eyes. For flammable and explosive reagents, keep away from fire sources and static electricity, and store and use them according to specifications to prevent safety accidents.