As a leading O-(4-Hydroxyphenyl)-2,3,5-Triiodotyrosine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of O- (4-hydroxyphenyl) -2,3,5-triiodotyrosine?
The chemical structure of O- (4-hydroxyphenyl) -2,3,5-triiodotyrosine is quite delicate. In this compound, the basic structure of tyrosine is its core. Tyrosine is an α-amino acid with amino and carboxyl groups.
In this compound, in the phenyl ring structure of tyrosine, hydroxyphenyl is introduced at the 4th position. The hydroxyl group of this hydroxyphenyl group has active chemical properties and can participate in many chemical reactions, forming hydrogen bonds between molecules, which has a great influence on its physical and chemical properties.
Furthermore, iodine atoms are introduced at the 2nd, 3rd, and 5th positions of the phenyl ring. The introduction of iodine atoms greatly changes the electron cloud distribution of molecules due to their large relative atomic mass and high electron cloud density, which in turn affects the physical properties of the compound such as polarity, boiling point, and melting point. And the existence of iodine atoms makes the molecule exhibit unique roles in certain biological activities or chemical reactions.
From the perspective of the overall chemical structure, O- (4-hydroxyphenyl) -2,3,5-triiodotyrosine forms a unique chemical entity through the ingenious combination of different functional groups, endowing it with specific physical, chemical and biological activities. It has potential important application value in many fields, such as medicinal chemistry, biochemistry, etc.
What are the main physical properties of O- (4-hydroxyphenyl) -2,3,5-triiodotyrosine?
O- (4-hydroxyphenyl) -2,3,5-triiodotyrosine is one of the organic compounds with various physical properties. Its appearance is often white to light yellow crystalline powder, which is visually recognizable.
When it comes to solubility, the substance is slightly soluble in water. Water is the source of all things, and many substances have different solubility characteristics in it. The degree of solubility of this compound in water is limited, reflecting the characteristics of the interaction between its molecules and water molecules. However, it can be slightly soluble in organic solvents, such as ethanol, acetone, etc. The molecular structure of organic solvents is different from that of water, and it can form a specific force with this compound, resulting in relatively good solubility in organic solvents.
Melting point is also an important physical property. O- (4-hydroxyphenyl) -2,3,5-triiodotyrosine has a certain melting point. At this temperature, the substance changes from solid to liquid. The exact melting point value may vary due to factors such as experimental conditions, but it is roughly within a specific range. The existence of the melting point indicates that the intermolecular force is overcome by sufficient energy at a certain temperature, and the molecular arrangement changes from an ordered solid state to a disordered liquid state.
In addition, the chemical properties of the compound are relatively stable at room temperature and pressure. However, under specific conditions, such as high temperature, strong acid, strong alkali environment, or contact with specific chemical reagents, its chemical structure may change. The balance between this stability and reactivity is determined by its molecular structure. Functional groups such as benzene ring, hydroxyl group and iodine atom interact with each other to shape their physical and chemical behavior.
In what fields is O- (4-hydroxyphenyl) -2,3,5-triiodotyrosine used?
O- (4-hydroxyphenyl) -2,3,5-triiodotyrosine is useful in various fields such as medicine and biochemical research.
In the field of medicine, it is of great significance in the research and treatment of thyroid-related diseases. Thyroid gland, an important part of human endocrine glands, secretes thyroid hormones, which are crucial for the regulation of body growth, development and metabolism. And O- (4-hydroxyphenyl) -2,3,5-triiodotyrosine is a key intermediate in thyroid hormone synthesis. The root cause of thyroid diseases such as hyperthyroidism and hypothyroidism is mostly related to abnormal thyroid hormone synthesis and secretion. By studying this substance, we can deeply explore the mechanism of thyroid hormone synthesis, and then find a new way for the diagnosis and treatment of related diseases. For example, the development of targeted drugs to regulate the synthesis of thyroid hormones and return thyroid function to normal.
In the field of biochemical research, this substance is also an important tool. Biochemical research aims to understand various chemical reactions and molecular mechanisms in organisms. O- (4-hydroxyphenyl) -2,3,5-triiodotyrosine is involved in the key biochemical process of thyroid hormone synthesis. Researchers can gain a deeper understanding of the fine regulation mechanism of hormone synthesis in organisms by exploring its properties and reaction characteristics. Such as exploring its reaction path under the action of different enzymes, and the influence of environmental factors on its reaction process. This not only helps to enrich the theoretical knowledge of biochemistry, but also provides theoretical support for the development of biotechnology, biopharmaceutical and other related industries.
In summary, O- (4-hydroxyphenyl) -2,3,5-triiodotyrosine is of great value in the fields of medicine and biochemical research, and has made significant contributions to human health and scientific progress.
What are the preparation methods of O- (4-hydroxyphenyl) -2,3,5-triiodotyrosine?
O- (4-hydroxyphenyl) -2,3,5-triiodotyrosine, although the method of preparation of this substance has not been detailed in ancient times, it can be roughly deduced according to today's chemical principles.
To prepare this substance, the first raw material is prepared. Iodine, tyrosine and benzene compounds with hydroxyl groups are all indispensable. Tyrosine, amino acid with amino and carboxyl groups, is the basis for the construction of this molecule. Iodine, used to introduce iodine atoms at specific positions of tyrosine. Benzene compounds with hydroxyl groups can provide the required functional groups for subsequent reactions.
At the beginning of the reaction, tyrosine is often dissolved in an appropriate solvent to facilitate the reaction. The choice of solvent requires consideration of its solubility to the reactants and its impact on the reaction. Organic solvents such as ethanol and dichloromethane can be selected. Then, at an appropriate temperature and pH, an iodine source is slowly added. There are various forms of iodine sources, iodine elemental substances, potassium iodide, etc. can be used. In this process, the reaction temperature needs to be carefully regulated. If the temperature is too high, it may cause side reactions to cluster and the product is impure. If the temperature is too low, the reaction will be slow and take a long time. Usually, the reaction temperature can be maintained in a moderate range, such as between room temperature and tens of degrees Celsius.
When iodine atoms are successfully introduced into tyrosine molecules, benzene compounds with hydroxyl groups are introduced. This reaction may require the help of catalysts to promote the formation of chemical bonds. There are many types of catalysts, and metal catalysts such as palladium and copper complexes can often effectively catalyze such reactions. During the reaction, it is also necessary to pay attention to the anhydrous and anoxic reaction environment, which may interfere with the reaction process and cause the quality of the product to be damaged.
After the reaction is completed, the product is often mixed with impurities such as unreacted raw materials and by-products. Therefore, it needs to be separated and purified to obtain pure O- (4-hydroxyphenyl) -2,3,5-triiodotyrosine. The method of separation can be selected according to the physical and chemical properties of the product and the impurity, such as the method of recrystallization, which uses the different solubility of the substance in different solvents to precipitate the product; and the method of chromatographic separation, which is separated according to the distribution coefficient between the substance in the stationary phase and the mobile phase. After these steps, a target product with higher purity can be obtained.
What is the market outlook for O- (4-hydroxyphenyl) -2,3,5-triiodotyrosine?
O- (4-hydroxyphenyl) -2,3,5-triiodotyrosine is one of the organic compounds. It is of great value in terms of market prospects.
In the field of Guanfu medicine, this compound plays an important role in the research of thyroid hormone synthesis. Thyroid hormones are related to human growth, development, metabolism and many other physiological processes. And this tyrosine derivative is a key object for exploring the mechanism of thyroid hormone production, and may help to develop new thyroid disease treatment drugs. Nowadays, the number of patients with thyroid diseases is increasing, and the market demand for related drugs is also expanding. With O- (4-hydroxyphenyl) -2,3,5-triiodotyrosine in the direction of pharmaceutical research and development, there is a potential broad market.
As for the scientific research level, it can be used as a biochemical reagent for in-depth analysis of the thyroid hormone biosynthesis pathway, helping researchers to clarify the molecular mechanism of each link. With the continuous advancement of life science research, the demand for precise biochemical reagents continues to rise, and this compound may occupy a place in the scientific research reagent market due to its unique role in thyroid research.
However, its market development also faces challenges. Synthesis of the compound may be difficult, and cost control is a major test. If costs cannot be effectively reduced, large-scale production and marketing activities are easily hindered. Moreover, the pharmaceutical research and development cycle is long and risky, and it needs to be strictly verified from basic research to clinical application, which is also an obstacle to its market entry.
Overall, although O- (4-hydroxyphenyl) -2,3,5-triiodotyrosine has an addressable market prospect, it has development opportunities in the fields of medicine and scientific research, but it also needs to overcome technical and cost problems in order to fully realize its market value.