O Iodobenzyl Alcohol

The chemical properties of O-iodobenzyl group and alcohol are quite interesting. For O-iodobenzyl group, the iodine atom is active. The cap iodine atom has a large radius and the C-I bond energy is relatively small, which makes the bond easy to break and exhibits good nucleophilic substitution reactivity.
When O-iodobenzyl group encounters alcohol, under suitable conditions, nucleophilic substitution reaction can occur. The hydroxyl oxygen atom of the alcohol is rich in lone pair electrons and has nucleophilic properties, which can attack the carbon atom connected to iodine in O-iodobenzyl group. In this process, the C-I bond breaks, and the iodine leaves in the form of iodine ions, which in turn generates new compounds or ethers.
If there is a base in the reaction system, the base can bind to the hydrogen of the alcohol hydroxyl group, enhance the nucleophilicity of the alcohol, and promote the reaction to occur more easily. And the rate and yield of the reaction are also affected by many factors. Such as reaction temperature, increasing the temperature can generally speed up the reaction rate, but if the temperature is too high or the side reaction increases. When the concentration of the reactant is high, the reaction rate will also be accelerated accordingly.
The choice of solvent is also crucial. Polar solvents can stabilize the ionic intermediates generated during the reaction and help the reaction to proceed. Alcohols with different structures also have an impact on the reaction due to their differences in steric resistance and electronic effects. Alcohols with low steric resistance are more likely to react close to O-iodobenzyl, while alcohols with higher electron cloud density have stronger nucleophilicity and higher reactivity.

O-iodobenzyl alcohol has a wide range of uses. First, it is an important intermediate in the field of pharmaceutical synthesis. Such as the preparation of antibacterial and anti-inflammatory drugs, with its structural properties, it can be linked to many active groups to construct compounds with specific pharmacological activities, which can help human health.
Second, it is a key building block in organic synthetic chemistry. Chemists can use it to carry out nucleophilic substitution, coupling and other reactions to build complex and diverse organic molecular structures and expand the types and functions of organic compounds.
Third, it also has its uses in the field of materials science. Or can participate in the preparation of materials with special properties, such as functional materials with optical and electrical response characteristics, to provide assistance for the innovation and development of materials.
Fourth, in scientific research and exploration, it is often used as a research tool. Scientists use its unique chemical properties to study reaction mechanisms, explore new synthesis paths, and promote the progress of chemical science. In short, O-iodobenzyl alcohol, with its diverse characteristics, plays an important role in many fields and has a profound impact on the development of science and technology and human life.

To prepare O-iodobenzyl alcohol, there are two methods. First, the O-iodobenzyl halogen interacts with the alkoxide. This halogen has good activity. In alkaline alkoxide solution, the halogen atom is easily replaced by an alkoxy group to form an ether of O-iodobenzyl alcohol. After that, by a mild hydrolysis method, the ether bond is broken to obtain O-iodobenzyl alcohol. The reaction conditions need to be controlled by temperature, and the appropriate alkali and solvent should be selected. If the temperature is high, the side reaction will start, and if it is low, the reaction will be delayed.
Second, O-iodobenzaldehyde is used as the starting point and is obtained by reduction. Commonly used reducing agents, such as sodium borohydride, are mild in nature and easy to control. In a suitable solvent, the aldehyde group is reduced to a hydroxyl group by sodium borohydride, and then becomes O-iodobenzyl alcohol. In this process, the properties of the solvent, the amount of reducing agent and the reaction time need to be considered. The solvent needs to have good solubility to the substrate and the reducing agent, and does not react with the two. The amount of reducing agent is determined according to the reaction measurement. If there is too much, it will be wasted, and if there is less, the reaction will be difficult. The time is also critical. If it is short, the reduction will not be completed, and if it is long, it will be by-product.
These two methods have their own advantages and disadvantages. In actual preparation, when the raw material is easy to obtain, the cost is high, and the purity of the product is required,

For O-iodobenzyl and alcohol, there are many matters that cannot be ignored during storage and transportation.
The first to bear the brunt is the temperature and humidity of the environment. These two have a great impact on its chemical properties. If the temperature is too high, it may cause chemical reactions to accelerate, or biodegradation, polymerization, etc., which will damage its quality. Therefore, the storage place should be controlled in a cool place, free from direct sunlight, such as in a cool warehouse room, and equipped with a temperature and humidity monitor to check it from time to time. If the humidity is high, or it may cause deliquescence, etc., it is necessary to keep the environment dry, and a desiccant can be placed near the reservoir.
The second is related to the packaging. The packaging must be tight and corrosion-resistant to prevent leakage. Containers of commonly used glass or specific plastic materials, when sealing, add gaskets, etc., to increase the effect of sealing. On the label, the composition, nature, hazards and other important items of the statement are clear to those who see it. When transporting, it is also necessary to choose suitable packaging, such as shock-proof and drop-proof equipment, to avoid bumps and damage to the container.
Furthermore, safety precautions are of paramount importance. O-iodobenzyl and alcohol may be flammable, toxic, etc. Storage place, when fireworks are prohibited, fire protection equipment, such as fire extinguishers, fire sand, etc. Personnel must use protective equipment, such as gloves, goggles, protective clothing, to prevent contact with skin, eyes, etc., to prevent poisoning or burns. During transportation, also follow safety regulations and avoid mixing with incompatible substances, such as strong oxidants, to prevent sudden risks.
Repeat, the storage period should also be paid attention to. Check its quality regularly and use it according to the specified period. If it expires, it should be disposed of according to the procedures, and it should not be discarded at will to prevent pollution to the environment.
In general, in the storage and transportation of O-iodobenzyl and alcohol, all details must be carefully taken to ensure safety and quality.

I think what you are asking is about the market price of O-iodobenzyl and Alcohol. However, in chemical products, the price of the two often varies depending on time, place, quality and supply and demand.
O-iodobenzyl is an important raw material for organic synthesis. Due to its difficulty in preparation and technical expertise, its price may be very high. If the quality is high and pure, the price per gram in the market may reach tens to hundreds of yuan. Alcohol, on the other hand, has a wide variety of categories, and the common ethanol, because it is widely used, the price is relatively cheap, ranging from liters, or a few yuan to tens of yuan. However, the price of industrial grade and medical and food grade is different.
In addition, if it is a special Alcohol, such as those with high purity, special structure or optical activity, its price will also increase greatly, or more than 100 yuan per gram. And when the market fluctuates, the price of raw materials, changes in processes, and policy regulations can all make its price fluctuate. To know its exact price, it is difficult to determine its price in one word by consulting chemical market merchants or observing recent transactions.