O Nitroiodobenzene
Iodobenzene

O-Nitroiodobenzene

Fengxi Chemical

    Specifications

    HS Code

    557524

    Chemical Formula C6H4INO2
    Molar Mass 249.006 g/mol
    Appearance Yellow - brown solid
    Melting Point 37 - 39 °C
    Boiling Point 265 - 267 °C
    Density 1.938 g/cm³
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like benzene, toluene
    Odor Characteristic, pungent
    Stability Stable under normal conditions, but may decompose on exposure to heat, light or strong oxidizing agents

    As an accredited O-Nitroiodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of O - nitroiodobenzene packaged in a sealed, chemical - resistant bottle.
    Storage O - nitroiodobenzene should be stored in a cool, dry, well - ventilated area, away from heat and ignition sources. It should be kept in a tightly - sealed container to prevent leakage. Store it separately from oxidizing agents, reducing agents, and bases, as it may react with them. Adhere to safety regulations to avoid potential fire, explosion, or release of harmful substances.
    Shipping O - nitroiodobenzene is shipped in well - sealed containers. Given its chemical nature, it requires proper handling to prevent leakage. Shipments must adhere to strict regulations for hazardous chemicals during transportation.
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    O-Nitroiodobenzene
    General Information
    Historical Development
    O-Nitroiodobenzene is an organic compound. In the field of chemistry, it gradually becomes more and more important. At the beginning, the research of the sages has not been deep, and the knowledge is still limited.
    As time goes by, the art of chemistry advances day by day. Scholars have thought hard to explore its properties and its system. In the past, the equipment was simple and the method was clumsy. It was difficult to obtain this thing. However, scholars are determined and not afraid of difficulties.
    After several generations, the technology is new. The more refined the experimental tool is, the more complete the theory is. The method of making O-Nitroiodobenzene has increased from complex to simple, and the yield has also increased. It is used in medicine and materials industries, and its use is increasing. Looking at its historical evolution, it really depends on the diligent study of scholars, so that its achievements today add a brilliant stroke to the history of chemistry.
    Product Overview
    "Overview of O-Nitroiodobenzene Products"
    Today there is a product named O-Nitroiodobenzene. Its color state is characteristic, often in the shape of [specific color state]. In terms of its properties, its chemical activity is significant, and it can show unique reaction characteristics in a specific chemical reaction environment.
    Preparation of this product follows a specific process path. It often starts with [related raw materials] and is delicately transformed through [key reaction steps]. This process requires strict control of reaction conditions, such as temperature, pressure, reaction time, etc. A slight difference will affect the purity and yield of the product.
    O-Nitroiodobenzene is widely used in many fields. In the field of organic synthesis, it is often used as a key intermediate to assist in the construction of complex organic compounds. In the field of materials science, it has also emerged, contributing to the development of new materials. It is an important substance that cannot be ignored in chemical research and industrial production.
    Physical & Chemical Properties
    O-Nitroiodobenzene is an organic compound. Its physical and chemical properties are particularly valued by scholars. Looking at its shape, at room temperature, or as a solid, the color state varies, depending on the preparation method and purity. Its melting point and boiling point are all characteristics. The melting point can be measured as a sign of its purity. The boiling point is related to its gasification temperature.
    On its chemical properties, above the benzene ring, the nitro group and the iodine atom stand side by side, making this compound have unique reactivity. Nitro has the ability to absorb electrons, causing the electron cloud density of the benzene ring to change, and it has a different performance in the electrophilic substitution reaction. Although the iodine atom is more active, it also participates in various reactions, or nucleophilic substitution, or conjugation in specific circumstances, depending on the reaction conditions and the reagents encountered. The properties of this compound are the way of organic synthesis, adding a variety of possibilities. Scholars often study it for clarity and use it in various ways of creation.
    Technical Specifications & Labeling
    O-Nitroiodobenzene is a chemical substance. The technical specifications for its preparation, the choice of the first raw materials. It is necessary to take pure iodine-benzene, followed by an appropriate amount of nitrate, and the ratio of the two should be precisely mixed. This is the key.
    When preparing, the temperature and time of the reaction must be strictly controlled. At a moderate temperature, let it react calmly and not be impatient. After the reaction is completed, the purification of the product is also a priority. When the method is delicate, remove its impurities and keep it pure.
    As for the identification of the product (commodity parameters), it is necessary to specify its purity geometry, number of impurities, and appearance. If the purity must reach a very high standard, the impurities must be minimal, and the appearance should be a specific color state. In this way, high-quality O-Nitroiodobenzene products can be obtained to meet the needs of all parties.
    Preparation Method
    The method of preparing O-Nitroiodobenzene, the first raw material and production process. Iodobenzene is used as the raw material, and concentrated nitric acid and concentrated sulfuric acid are mixed to form mixed acids. The two are the key raw materials.
    The production process involves first adding iodobenzene to the mixed acid and stirring at low temperature. This is the initial step of the reaction. Temperature control is very important to prevent side reactions. When the reaction is stable, gradually heat up to a suitable range to make the reaction sufficient.
    The reaction steps are as follows: first mix the acid and prepare it, add the iodobenzene slowly, stir at an initial low temperature, and then heat up to promote the reaction. During the period, the reaction state is closely observed to ensure that the reaction goes as expected.
    Catalytic mechanism, nitric acid is an electrophilic reagent in the mixed acid, and sulfuric acid helps it to form nitroyl positive ions. This ion undergoes electrophilic substitution with iodobenzene to obtain O-Nitroiodobenzene. In this way, according to the raw materials, process, steps and catalytic mechanism, O-Nitroiodobenzene can be prepared.
    Chemical Reactions & Modifications
    To taste the wonders of chemical industry, it is related to reaction and modification, and the same is true for the products of O-Nitroiodobenzene. In the process of chemical reaction, iodobenzene is initially used as a base, supplemented by nitrate agent, and after ingenious proportions, it is promoted to phase in a specific temperature and pressure environment. However, the efficiency of the initial method is not perfect, and the product is sometimes impure.
    After further study, the reaction medium is changed, and the catalyst is easy to catalyze. The temperature and pressure regulation is more accurate. This change also greatly increases the reaction rate, the yield is also significantly improved, and the purity of the product is higher. Watch its modification, or add groups to change its properties, or adjust the structure to suit other uses. Such as adding hydrophilic groups to make it easier to disperse in the aqueous phase; changing the spatial structure to meet the special reaction needs. After various adaptations and modifications, the products of O-Nitroiodobenzene are increasingly effective in the fields of medicine and materials, and the prospect is wider.
    Synonyms & Product Names
    In recent years, in the field of chemistry, there is a thing called O-Nitroiodobenzene, which is valued by the industry. The name of this substance varies from name to name, and there are also different trade names in the industry.
    In terms of its name, O-Nitroiodobenzene is established according to the rules of chemical naming. However, in the market, it may be called by its nature and its use. Between transactions and discussions among peers, the names are mixed, or they are simple, or they are made by convention.
    The name of its trade name also varies from business to business. In order to recognize the excellence of its goods, or to show the integrity of its origin, various merchants have established their own names. Although the names are different, they all refer to this O-Nitroiodobenzene. These changes are all due to the needs of the market and the convenience of everyone. When studying and making a living, it is necessary to understand its various names in order to obtain its true meaning, to walk freely in the chemical industry, and to communicate and spend.
    Safety & Operational Standards
    Specifications for the safe production and operation of O-Nitroiodobenzene
    O-Nitroiodobenzene is a common compound in chemical preparation. Its special nature is related to the safety of the experimenter and the effectiveness of the preparation. Therefore, it is essential to determine its safe production and operation specifications.
    #1. Storage rules
    O-Nitroiodobenzene should be stored in a cool, dry and well-ventilated place. Keep away from fire and heat sources to prevent it from decomposing due to heat or causing other hazards. The temperature of the storage should be controlled within a specific range and should not be too high. And it should be stored separately from oxidizing agents, reducing agents, alkalis, etc., and should not be mixed with storage to prevent violent chemical reactions from occurring and causing safety risks. The storage area should be equipped with suitable materials to contain leaks in case of accident.
    #2. Standard operation
    During operation, the experimenter must wear suitable protective equipment, such as protective clothing, gloves and goggles, to guard against possible hazards. The operating environment needs to be well ventilated, preferably in a fume hood to avoid the accumulation of harmful gases. When taking O-Nitroiodobenzene, the action should be stable and accurate to prevent it from spilling. If it is accidentally spilled, do not panic, and deal with it quickly according to the established procedures. Small leaks can be absorbed by inert materials such as sand and vermiculite; if there are large leaks, it is necessary to build a dike or dig a pit to contain them, and then deal with them properly.
    During the reaction process, strictly control the temperature and speed, and accurately grasp the reaction conditions according to the reaction mechanism and characteristics. Pay close attention to the changes in the reaction. If there is any abnormality, take corresponding measures immediately to ensure the safety and success of the experiment.
    #3. Emergency measures
    If someone is exposed to O-Nitroiodobenzene and causes physical discomfort, quickly move to a fresh air place. If it comes into contact with the skin, immediately rinse with a large amount of flowing water; if it enters the eyes, lift the eyelids, rinse with flowing water or normal saline, and seek medical attention in time. In the event of a fire, due to the characteristics of O-Nitroiodobenzene, appropriate fire extinguishing agents, such as dry powder, carbon dioxide, etc., should be selected. Do not blindly rescue.
    In conclusion, the safe production and operation practices of O-Nitroiodobenzene are the cornerstone of experimental safety and product quality, and everyone should strictly abide by them.
    Application Area
    O-Nitroiodobenzene, the application field of this substance, is quite important. In the field of organic synthesis, it is often a key intermediate. With it as a starting material, it can be prepared through various reaction paths to produce many organic compounds with special structures and functions.
    In the field of pharmaceutical research and development, based on this, it may be able to synthesize molecules with specific pharmacological activities, contributing to the creation of new drugs. In the field of materials science, the products derived from it may endow materials with unique electrical and optical properties, and be used in optoelectronic devices.
    And in the production of fine chemicals, it can also be used as an important reagent to help synthesize high-value-added fine chemicals and meet the needs of different industries for special chemicals. It is actually widely used and has promising prospects.
    Research & Development
    In recent years, Yu has dedicated himself to the field of organic synthesis, especially focusing on the research of O-Nitroiodobenzene. At the beginning, the synthesis methods were mostly complicated and the yield was not ideal. Yu worked hard, read the classics, visited various houses, and hoped to find the way to optimization.
    is to explore the reaction mechanism, and investigate the influence of various reagents and conditions. After repeated experiments, a breakthrough was finally achieved. With a specific catalyst and suitable temperature and pressure, the yield of the reaction was significantly improved, and the purity of the product was also good.
    However, the research does not stop there. Consider the potential applications of this substance in the fields of medicine, materials, etc., and expand its derivative synthesis path. With continuous research, O-Nitroiodobenzene not only becomes more mature in synthesis technology, but also shines brightly in practical applications, contributing to the development of related industries.
    Toxicity Research
    Since modern times, chemical refinement has resulted in the emergence of various new substances. In today's words, O-Nitroiodobenzene, the study of its toxicity is crucial.
    Guanfu O-Nitroiodobenzene has a unique molecular structure and contains nitro and iodine groups. Nitro is highly oxidizing; iodine groups also have their own characteristics. The two co-live in one molecule, resulting in complex properties.
    Taste all kinds of biological tests. In mice, fed with food containing O-Nitroiodobenzene, soon, the mouse's coat color is withered, the movement is slow, and the organs are also abnormal. Liver, the center of metabolism, is affected by it and has dysfunction.
    Investigate the reason for its toxicity, or due to molecular entry into the body, the structure of the cell is broken, and the order of metabolism is chaotic. Nitro oxidation is strong, damaging the lipids and proteins in the cell, causing cell dysfunction. Iodine also interferes with biochemical reactions and involves various physiological functions.
    In summary, O-Nitroiodobenzene is significantly toxic. When developing and applying, care should be taken to prevent it from harming the young and ensure the safety of all beings and the peace of the environment.
    Future Prospects
    Now O-Nitroiodobenzene has great potential in the field of chemistry. Although the current research may only scratch the surface, the future prospects are really fascinating.
    Our generation expects that in the future, the study of its properties will be more profound. The relationship between its structure and properties will be thoroughly analyzed, and a more delicate synthesis path may be developed based on this, improving the efficiency and quality of the output.
    Furthermore, O-Nitroiodobenzene may emerge in the fields of materials science, drug development and other fields. Over time, it can be turned into a key ingredient in innovative drugs for human health and well-being; or it can play a pivotal role in the creation of new functional materials and promote the leap of science and technology.
    Although the road ahead may be full of thorns, the road of scientific research requires fearless exploration. I firmly believe that with unremitting research, O-Nitroiodobenzene will be able to shine brightly and achieve future brilliance.
    Where to Buy O-Nitroiodobenzene in China?
    As a trusted O-Nitroiodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading O-Nitroiodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of O-nitroiodobenzene?
    O-nitroiodobenzene is also an organic compound. Its physical properties are quite specific and have unique properties. Looking at its color, it is often in the shape of a light yellow crystal, delicate and shiny, and it seems to flicker under light. This is because of the unique arrangement of its molecular structure, which has such an effect on the reflection and refraction of light. When it comes to the melting point, it is between 36 and 38 degrees Celsius. When the ambient temperature gradually rises, its solid state begins to melt into a liquid state. This phase transition process is very wonderful, because the force between molecules changes at this specific temperature, resulting in the disintegration of the lattice structure. In terms of boiling point, it is about 279 degrees Celsius. Under this high temperature, the liquid O-nitroiodobenzene is converted into a gaseous state, and the molecules gain enough energy to break free from each other and escape into space. Furthermore, its density is greater than that of water, about 2.079g/cm ³. If it is placed in the same place as water, it must sink to the bottom, because its mass per unit volume is more considerable. Solubility is also an important physical property. In water, its solubility is extremely low, and it is difficult to form an effective interaction due to the large difference between the polarity of the molecules and the polarity of the water molecules. However, in organic solvents such as ethanol and ether, it has good solubility and can be miscible with it. This is due to the principle of similar miscibility, and the force between organic solvents and O-nitroiodobenzene molecules is conducive to their mutual dispersion. In addition, O-nitroiodobenzene has a certain degree of volatility. In the air, although slowly but continuously, some molecules are converted from liquid to gaseous and escape, emitting a unique odor. This odor is slightly irritating, and its existence can be recognized by smell.
    What are the chemical properties of O-nitroiodobenzene?
    O-nitroiodobenzene is also an organic compound. It has a number of chemical properties, which is now the case of Jun Chen. First of all, its reactivity. On the benzene ring, the nitro group is a strong electron-absorbing group, and the iodine atom is a weak electron-absorbing group. The two cooperate to reduce the electron cloud density of the benzene ring, making it difficult for the electrophilic substitution reaction to occur. If the electrophilic reagent wants to attack the benzene ring, it needs to overcome the obstacle of the lack of electron cloud. When encountering nucleophilic reagents, the situation is different. The presence of nitro groups can activate the ortho and para-sites of the benzene ring, making the nucleophilic substitution reaction easier to carry out. The nucleophilic test agent can attack the benzene ring, and the intermediate transition will eventually lead to the replacement product. Nitro groups can be reduced. Under suitable conditions, such as iron and hydrochloric acid as reducing agents, nitro groups can be gradually converted into amino groups to obtain o-amino iodobenzene. This reaction is very important in organic synthesis, which can introduce amino functional groups and expand the application of compounds. In addition, the properties of iodine atoms are also critical. Iodine atoms can participate in a variety of reactions, such as the Ullmann reaction. Under copper catalysis and other conditions, the iodine atoms of O-nitroiodobenzene can be coupled with other compounds containing active groups to form carbon-carbon bonds or carbon-hetero bonds to form more complex organic structures. In addition, O-nitroiodobenzene has certain sensitivity to light and heat. Under high temperature or light, decomposition or other side reactions may be triggered, so it is necessary to pay attention to environmental conditions during storage and use to prevent deterioration and ensure its chemical stability, so as to facilitate organic synthesis and related research.
    What are the main uses of O-nitroiodobenzene?
    O-nitroiodobenzene, the Chinese name o-nitroiodobenzene. Its main use, due to its unique chemical properties, is very important in the field of organic synthesis. First, it is often the key intermediate for the synthesis of complex organic compounds. Chemists use it as a base, and by means of subtle chemical reactions, various functional groups can be added to construct multi-component structures. For example, when constructing nitrogen-containing heterocyclic compounds, the nitro and iodine atoms of o-nitroiodobenzene can participate in the cyclization reaction respectively. After ingeniously designing steps, the complex cyclic structure can be accurately constructed, laying the foundation for the research and development of new compounds in medicinal chemistry and materials science. Second, in the field of materials science, it participates in the synthesis of materials with special photoelectric properties. The structure of o-nitroiodobenzene can be modified to regulate the electron cloud distribution of materials, which in turn affects the optical absorption, emission and electrical conductivity of materials. Scientists use this to synthesize new organic semiconductor materials, which can be used in organic Light Emitting Diodes (OLEDs), organic solar cells, etc., to improve the performance and efficiency of devices. Third, it also makes important contributions in the process of drug research and development. Through the structural modification and derivatization of o-nitroiodobenzene, bioactive compounds can be obtained. Using it as a starting material, researchers introduced bioactive fragments through multi-step reactions to screen potential pharmacologically active lead compounds, providing the possibility for the development of new drugs. In conclusion, although O-nitroiodobenzene is an organic compound, it plays an irreplaceable role in many key fields such as organic synthesis, materials science, and drug research and development by virtue of its unique structure and reactivity, and promotes technological innovation and development in various fields.
    What are the synthesis methods of O-nitroiodobenzene?
    There are two common methods for making O-nitroiodobenzene. First, iodobenzene is used as the starting material and obtained by nitrification. In an appropriate solvent, such as glacial acetic acid, iodobenzene and mixed acid (mixture of nitric acid and sulfuric acid) are added to control the temperature to make the two nitrify. In this reaction, the ratio of mixed acid and the temperature affect the yield and purity of the product. If the temperature is too high, it is easy to produce by-products of polynitro substitution; if the temperature is too low, the reaction rate is slow. Second, it is prepared by Sandmeier reaction starting with o-nitroaniline. First, o-nitroaniline, hydrochloric acid and sodium nitrite are made into diazonium salts at low temperature, and then co-heated with potassium iodide solution. The diazonium groups are replaced by iodine atoms to obtain O-nitroiodobenzene. When preparing diazonium salts, the temperature needs to be strictly controlled at low temperature, generally 0-5 ° C, to prevent the decomposition of diazonium salts. The advantage of Sandmeier reaction is that it has good selectivity and can obtain products with higher purity. However, no matter what method, it needs to be carefully operated and the reaction conditions are carefully controlled to increase the yield and purity of O-nitroiodobenzene.
    What are the precautions for O-nitroiodobenzene during storage and transportation?
    O-nitroiodobenzene is also an organic compound. During storage and transportation, many matters need to be paid attention to. When storing, the first environment. It should be placed in a cool and ventilated warehouse, away from fires and heat sources. This substance may be dangerous due to heat or exposure to open flames. The temperature of the warehouse should not be too high, and should usually be controlled within an appropriate range to prevent it from deteriorating or causing accidents due to temperature influence. Furthermore, it should be stored separately from oxidants, reducing agents, alkalis, etc., and must not be mixed. Because of its active chemical properties, contact with the above substances is prone to chemical reactions, or cause fires, explosions and other disasters. And the storage area should be equipped with suitable materials to contain the leakage, in case of leakage, it can be properly handled in time to avoid greater harm. When transporting, caution is also required. The transportation vehicle should be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment. Ensure that during transportation, if there is an emergency situation, it can be responded to quickly. The handling process must be light and light to prevent damage to the packaging and containers. Because of its certain danger, damaged packaging can easily cause leakage, endangering transportation safety and the surrounding environment. The transportation process should also follow the specified route, and do not stop in densely populated areas and residential areas to avoid threats to the public. In short, the storage and transportation of O-nitroiodobenzene must strictly abide by the norms and act cautiously, so that the security is not at risk.