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What is the chemical structure of Octakis- (6-iodo-6-deoxy) -γ-cyclodextrin?
Octakis- (6-iodo-6-deoxy) -γ-cyclodextrin is a derivative of γ-cyclodextrin obtained by chemical modification. Its chemical structure is based on γ-cyclodextrin. This γ-cyclodextrin is connected end to end by eight glucose units via α-1,4-glycoside bonds, and has a cyclic structure with a cone-shaped lumen and certain hydrophobic properties.
On this basis, a substitution reaction occurs at the C-6 hydroxyl group of the eight glucose units in the γ-cyclodextrin molecule, and the hydroxyl group is replaced by an iodine atom to form Octakis- (6-iodo-6-deoxy) -γ-cyclodextrin. In this way, iodine atoms are introduced into the γ-cyclodextrin molecule to change its physical and chemical properties. Iodine atoms have a large atomic radius and electronegativity, which affect molecular polarity, hydrophobicity and interaction with guest molecules after introduction.
This structural change allows Octakis- (6-iodo-6-deoxy) -γ-cyclodextrin to exhibit unique inclusion properties in the field of host and guest chemistry, forming inclusion compounds with specific guest molecules through van der Waals forces, hydrogen bonds, and hydrophobic interactions; in drug delivery systems, or due to the introduction of iodine atoms, new properties are given to materials, such as changing drug solubility, stability, and targeting; in the field of materials science, its structural properties may be used to construct new functional materials, such as for adsorption and separation of specific substances.
What are the main uses of Octakis- (6-iodo-6-deoxy) -γ-cyclodextrin?
Octakis- (6-iodo-6-deoxy) -γ-cyclodextrin, that is, octa (6-iodo-6-deoxy) -γ-cyclodextrin, has a wide range of uses and is useful in various fields of scientific research and industry.
In the context of scientific research, first, it is often used as a key material for supramolecular chemistry research. Due to its unique molecular structure, it can interact with many guest molecules non-covalently, such as inclusion, to form host-guest complexes. Therefore, it can be used to explore the mechanism of intermolecular interactions, such as the analysis of host-guest binding mode, force strength, etc., to provide a key basis for the construction and performance optimization of supramolecular systems. Second, it also has potential in the field of drug delivery. It can include insoluble drugs, improve drug solubility and stability, enhance drug bioavailability, and open up a path for the research and development of new drug carriers.
In terms of industry, in materials science, it can be used to prepare functional materials. Such as compounding with polymers, giving materials special identification properties or improving physical and chemical properties of materials, such as improving material adsorption and selectivity, etc., showing value in separation membranes, sensor material preparation, etc. In the food industry, it can be used for food preservation and flavor improvement. By including easily oxidized and volatile components in food, prolong the shelf life of food, retain flavor substances, and improve food quality. Octakis- (6-iodo-6-deoxy) -γ-cyclodextrin is a valuable material for scientific research and industrial practice due to its special structure, promoting technological innovation and development in many fields.
What is the synthesis of Octakis- (6-iodo-6-deoxy) -γ-cyclodextrin?
Octakis- (6-iodo-6-deoxy) -γ-cyclodextrin is a compound of considerable research value. Its synthesis method, although the ancient book "Tiangong Kaiwu" does not contain this specific thing, it can be deduced according to the principles of ancient chemical synthesis.
To make Octakis- (6-iodo-6-deoxy) -γ-cyclodextrin, the first step is to use γ-cyclodextrin as the starting material. γ-cyclodextrin has a special cyclic structure, and the hydroxyl group on it is the reactive activity check point.
One method can first react γ-cyclodextrin with an appropriate protective group to protect the specific hydroxyl group from accidental participation in subsequent reactions. Then, with an iodine-containing reagent, such as potassium iodide, in combination with an appropriate oxidizing agent, or directly with an active iodine reagent, the 6-position hydroxyl group undergoes a substitution reaction, introducing iodine atoms to form a 6-iodo-6-deoxy structure. When reacting, pay attention to the reaction conditions, such as temperature, pH and reaction time. If the temperature is too high, or side reactions occur frequently, if it is too low, the reaction will be delayed. PH also affects the reaction process and product purity.
After the 6-position iodine substitution reaction is completed, carefully remove the previously added protective groups, and obtain pure Octakis- (6-iodo-6-deoxy) -γ-cyclodextrin through multi-step separation and purification methods, such as column chromatography, recrystallization, etc.
The entire synthesis process requires fine control of each step of the reaction and careful operation to obtain this target product. Although the ancient method did not contain this exact synthesis, according to the principle of chemical changes, this compound may be successfully prepared by following this path.
What are the physical properties of Octakis- (6-iodo-6-deoxy) -γ-cyclodextrin?
Octakis- (6-iodo-6-deoxy) -γ-cyclodextrin, that is, octa (6-iodo-6-deoxy) -γ-cyclodextrin, is a special cyclodextrin derivative. Its physical properties are interesting and have potential applications in many fields.
When it comes to appearance, it is usually in the form of a white to quasi-white powder, with a fine and uniform texture, like the purity of early winter snow. This form is easy to store and transport, and is also conducive to accurate use in various experiments and production processes.
In terms of solubility, this substance exhibits unique properties in water. Although it is not very soluble in water, it can form a relatively stable dispersion system in water under moderate stirring and heating conditions. Like fine sand under the ingenious action of water flow, it is uniformly integrated into it. In addition, it also has a certain solubility in some organic solvents, such as ethanol, acetone, etc. This solubility characteristic provides a broad space for its application in different reaction systems.
Thermal stability deserves considerable attention. Within a certain temperature range, eight (6-iodine-6-deoxygenation) -gamma-cyclodextrin can maintain structural stability, acting like a strong fortress against external temperature changes. When the temperature gradually rises to a certain level, its structure will gradually change and begin to decompose. This property is crucial in processes involving high temperature treatment, and precise temperature control is required to ensure that its performance is not affected.
Crystal structure is also one of its important physical properties. Through X-ray diffraction and other techniques, it is found that its crystal structure presents a regular and orderly arrangement, and the atoms are connected to each other in a specific way to form a unique spatial configuration. This crystal structure not only affects its own physical properties, but also has a profound impact on its interactions with other molecules. Like a precise lock cylinder, it determines the "key" molecule that can be matched with it.
In conclusion, the physical properties of octa (6-iodine-6-deoxy) -γ-cyclodextrin are unique and complex, which lays a solid foundation for its applications in drug delivery, molecular recognition, catalysis and other fields.
What is the price range of Octakis- (6-iodo-6-deoxy) -γ-cyclodextrin in the market?
I don't know if Octakis- (6-iodo-6-deoxy) -γ-cyclodextrin is in the market price range. This is a more professional chemical substance, and its price is often affected by many factors.
First, purity is the key factor. If the purity is extremely high, almost perfect, and there is no impurity doping, the price will be high; on the contrary, if the purity is slightly lower, it contains some impurities, and the price may be relatively low.
Second, the market supply and demand situation has a great impact. If the demand is strong and many buyers are competing to buy it, and the supply is limited, it is like a rare treasure, and the price will rise; if the demand is small and the supply is sufficient, it is difficult to get high.
Third, the production process also plays a role. If the production of this substance requires complicated and difficult processes, consumes a lot of resources and manpower, and the cost increases, the price will also rise; if the production process is relatively simple, the cost is controllable, and the price may be close to the people.
In addition, different merchants have different pricing strategies, coupled with factors such as transportation and storage conditions, which will cause prices to fluctuate. To know the exact price range, you need to consult the relevant chemical reagent suppliers in detail, or explore on the professional chemical product trading platform to get an accurate number.