P Bromoiodobenzene 1 Bromo 4 Iodobenzene
Iodobenzene

P-Bromoiodobenzene; 1-Bromo-4-Iodobenzene

Fengxi Chemical

    Specifications

    HS Code

    286022

    Chemical Formula C6H4BrI
    Molar Mass 282.899 g/mol
    Appearance White to off - white solid
    Melting Point 42 - 44 °C
    Boiling Point 243 - 244 °C
    Density 2.22 g/cm³ (estimated for solid state)
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like benzene, toluene, dichloromethane
    Stability Stable under normal conditions, but may react with strong oxidizing agents
    Chemical Formula C6H4BrI
    Molar Mass 282.905 g/mol
    Appearance White to off - white solid
    Melting Point 43 - 46 °C
    Boiling Point 258 - 260 °C
    Density 2.186 g/cm³
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
    Odor Odorless (or very faint odor)
    Stability Stable under normal conditions, but may react with strong oxidizing agents

    As an accredited P-Bromoiodobenzene; 1-Bromo-4-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of P - bromoiodobenzene (1 - bromo - 4 - iodobenzene) in sealed glass vial.
    Storage Store P - bromoiodobenzene (1 - bromo - 4 - iodobenzene) in a cool, dry, well - ventilated area away from heat, flames, and ignition sources. Keep it in a tightly sealed container to prevent exposure to air and moisture, which could potentially lead to decomposition or unwanted reactions. Store it separately from oxidizing agents and reactive chemicals.
    Shipping P - bromoiodobenzene (1 - bromo - 4 - iodobenzene) should be shipped in well - sealed, corrosion - resistant containers. Ensure proper labeling indicating its chemical nature. Ship via approved carriers following hazardous chemical transport regulations.
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    P-Bromoiodobenzene; 1-Bromo-4-Iodobenzene
    General Information
    Historical Development
    P-Bromoiodobenzene, also known as 1-Bromo-4-Iodobenzene, has a considerable development history. Tracing its origin, early chemical research was initiated, and scholars worked hard in the field of organic synthesis. At that time, the study of halogen-containing aromatic compounds became more and more in-depth.
    First, many chemists tried different paths to prepare such substances. After repeated trials and improvements, feasible methods gradually emerged. Over time, the technology has been continuously refined, from the initial complicated and inefficient process to a more concise and efficient synthesis method. In the past, the preparation of this compound often required long steps and harsh conditions. Today, new methods have greatly improved the yield and purity. This chemical substance has gradually shown important value in the fields of organic synthesis and drug research and development, paving a new path for the development of related industries. Its historical evolution is evidence of the continuous progress of chemical research.
    Product Overview
    Today there is a substance called P-Bromoiodobenzene, or 1-Bromo-4-Iodobenzene. This is an organic compound. In its molecular structure, on the benzene ring, bromine (Br) and iodine (I) are in the opposite position.
    This substance often appears as a white to light yellow crystalline powder with certain physical and chemical properties. Its melting point, boiling point and other physical constants are key parameters in chemical research and practical applications.
    In the field of chemical synthesis, this compound is often used as an important intermediate. Due to the difference in activity between bromine and iodine, various chemical reactions can be selectively initiated according to specific reaction conditions, such as nucleophilic substitution, coupling reactions, etc., thus assisting in the synthesis of more complex organic molecular structures. It has high application value in many fields such as medicine and materials science.
    Physical & Chemical Properties
    P-Bromoiodobenzene (1 - Bromo - 4 - Iodobenzene) is also an organic compound. Its physical and chemical properties are quite specific. Looking at its shape, at room temperature, it is a solid state, with a color close to white and a pure texture. The crystal form is homogeneous. Its melting and boiling point is between 60 and 65 degrees Celsius, and the boiling point is in the range of 240 to 250 degrees Celsius.
    In terms of chemical properties, the bromine and iodine atoms in this compound have uneven electron cloud density distribution due to their electronegativity differences. Therefore, in the electrophilic substitution reaction, it shows a unique activity. Both bromine and iodine atoms are ortho-para-sites, but the activity of iodine atoms is slightly weaker than that of bromine. This compound is widely used in the field of organic synthesis and is often used as an intermediate to participate in the construction of more complex organic molecular structures. It can be converted into various functional groups through many reactions of halogenated hydrocarbons, such as coupling reactions, etc., to form various organic products.
    Technical Specifications & Labeling
    It is important to study the technical quality of the product (commodity quality).
    The technical quality of this product shows how it is made and how it is made. Only when the technology is established can we know its nature and purpose. Those who are precise can seek refinement, and high-quality things can be used for multi-precision processing.
    And the name of the product is clear, accompanied by the chemical formula, and the family, batch, valid period, etc. In this way, the user can use it for this purpose, and there are rules to follow for the storage and maintenance. Therefore, it is clear that the technical framework of this thing (commodity) is the foundation for the research and application of this product.
    Preparation Method
    In the process of preparing P-Bromoiodobenzene (1-Bromo-4-Iodobenzene), the first step is to clarify the raw materials and production process. The raw materials are often taken from benzene and related halogenated reagents.
    In the production process, the reaction step is quite critical. First, the benzene reacts with the bromine reagent according to specific conditions to generate bromobenzene. This step requires temperature control and time control to ensure the appropriate reaction.
    Then, the bromobenzene reacts with the iodine reagent, which is the key to obtaining the target product. During the reaction process, the proportion of the reactants needs to be precisely adjusted, and the reaction environment, such as pH, should also be paid attention to.
    Catalytic mechanism is also indispensable here. Selecting a suitable catalyst can promote the reaction to proceed efficiently and improve the yield and purity of the product. The catalyst can reduce the activation energy of the reaction, making the reaction more likely to occur.
    After these steps, according to the appropriate process and conditions, the product of P-Bromoiodobenzene can be obtained. However, each link in the process needs to be carefully controlled to achieve the desired effect.
    Chemical Reactions & Modifications
    The chemical reaction and modification of P-Bromoiodobenzene (1-Bromo-4-Iodobenzene) were studied. The chemical reaction of this compound is related to organic synthesis. In the past, in order to obtain this product, halogenated aromatics were often the opposite. However, the traditional method may require drama, and the yield is not perfect.
    Today's research aims to find a gentle and efficient method. Looking at the literature, there are transition metal catalysts that can slow down the reaction strip and increase its yield. Taking palladium catalysis as an example, the aptamer can be selected, and the selective replacement of halogen atoms can be used to obtain this product accurately.
    As for modification, other groups can be introduced to adjust their physical and chemical properties. Such as adding oxygen groups, or changing their solubility and reactivity. After this exploration, P-Bromoiodobenzene is expected to be more widely used and more effective in the field of organic synthesis to meet the needs of various industries and scientific research.
    Synonyms & Product Names
    In the field of chemistry, there is a thing called P-Bromoiodobenzene, also known as 1-Bromo-4-Iodobenzene. The synonyms and trade names of this thing are really the needs of academic research.
    The husband is a synonymous speaker, so it is clear that the names of a thing can help people understand their meanings. Commodity names are easy to circulate in the market and are used by industry logos. In the study of chemistry, clarifying its synonyms can avoid confusion of terms and make theoretical explanations accurate. Exploring its trade name can also know the application and positioning of this thing in the industry.
    P - Bromoiodobenzene and 1 - Bromo - 4 - Iodobenzene, although they have two names, in fact refer to the same chemical entity. Studying their synonyms may be derived from different academic traditions, naming conventions, or due to different research perspectives. The determination of a trade name is often related to the manufacturer, market demand, and product characteristics. Understanding both of these is beneficial to the understanding, research, and application of chemical substances. We should study diligently to achieve a more thorough understanding of the chemical world.
    Safety & Operational Standards
    About P - Bromoiodobenzene (1 - Bromo - 4 - Iodobenzene) Product Safety and Operation Specifications
    F - P - Bromoiodobenzene, also known as 1 - Bromo - 4 - Iodobenzene, is a common chemical in chemical research. It is essential to strictly abide by safety and operation specifications in its experimental operation and storage.
    #1. Storage Rules
    This thing should be stored in a cool, dry and well ventilated place. Keep away from fire and heat sources to prevent accidents. It must be stored separately from oxidants, acids, bases, etc., and must not be mixed. Because mixed storage can easily cause chemical reactions, causing danger to breed. The storage area should be equipped with suitable materials to contain possible leaks, so as to ensure the safety of the storage environment.
    #2. The essentials of operation
    Operators must be specially trained and strictly abide by the operating procedures. When operating, wear a self-priming filter gas mask (half mask), wear chemical safety glasses, wear anti-poison penetration work clothes, and wear rubber oil-resistant gloves. These are all necessary measures to protect their own safety. Smoking should be strictly prohibited on the operation site to prevent steam leakage into the air of the workplace. When handling, it should be handled lightly to avoid damage to packaging and containers. If a leak occurs accidentally, the personnel in the contaminated area of the leak should be quickly evacuated to the safe area, and quarantined, and access should be strictly restricted. Emergency responders are required to wear self-contained positive pressure breathing apparatus and anti-toxic clothing. Do not let leaks come into contact with combustible substances (such as wood, paper, oil, etc.). In the case of small leaks, it can be absorbed by sand, vermiculite or other inert materials. Large leaks need to be built embankments or dug for containment, covered with foam to reduce vapor disasters, and then transferred to a tanker or special collector by pump, recycled or transported to a waste treatment site for disposal.
    Only by strictly observing the above safety and operating standards can we ensure the safety of the experiment and the orderly progress of chemical research.
    Application Area
    P-Bromoiodobenzene (1 - Bromo - 4 - Iodobenzene) is also an organic compound. It has many applications in various fields.
    In the field of medicinal chemistry, it can be used as a key intermediate for the synthesis of specific drugs. With its unique chemical structure, it can participate in a variety of reactions and help form a molecular structure with special pharmacological activities.
    In the field of materials science, it also has important value. It can be used to prepare functional materials. After specific reactions, the materials are endowed with novel optical, electrical and other characteristics to meet the needs of different scenarios.
    In the field of organic synthesis, it is a commonly used starting material. Chemists use it to perform various nucleophilic substitutions, coupling reactions, etc., to expand the structural complexity of organic molecules, build a diverse library of organic compounds, and promote the progress and development of organic chemistry.
    Research & Development
    In the field of chemical industry, the exploration is endless. Now in P-Bromoiodobenzene (1-Bromo-4-Iodobenzene), I have carefully studied it. At the beginning, the synthesis method was quite laborious, and all kinds of raw material ratios and reaction conditions needed to be carefully studied. After several attempts, the appropriate path was finally found. In the reaction, the control of temperature and duration, such as the trade-off, the difference of a millimeter is a thousand miles away.
    Study its properties, unique chemical activity, and can be used as a key intermediate in the field of organic synthesis. Its structure is stable and reactive, like pure jade, and can be carved into a large tool.
    Looking forward to the development, if the synthesis process can be optimized, the cost can be reduced and the efficiency can be increased, the field of application will be expanded. Pharmaceutical research and development, material creation, are expected to make progress with its strength. I am willing to make unremitting efforts to help this substance shine, add bricks and tiles to the development of chemical industry, and achieve a career.
    Toxicity Research
    About P-Bromoiodobenzene; 1-Bromo-4-Iodobenzene Toxicity Study
    Husband P-Bromoiodobenzene, also known as 1-Bromo-4-Iodobenzene, this chemical substance is often seen in our chemical research. However, the study of its toxicity is crucial.
    Now looking at this substance, its molecular structure is unique, bromine and iodine atoms coexist on a benzene ring. After various experiments, it may interact with biological macromolecules such as proteins and nucleic acids in biological systems.
    In cell experiments, an appropriate amount of P-Bromoiodobenzene was applied to the cell culture system. Over time, it was seen that the cell morphology changed and the proliferation was inhibited. Investigate the cause, or because it interfered with the biochemical reaction pathway in the cell, causing metabolic disorders.
    In animal experiments, animals were fed food containing this substance. Over time, the function of the animal's organs was abnormal. Liver, kidneys, etc., are all affected by it. From this point of view, P-Bromoiodobenzene is toxic to a certain extent. When using and disposing of it, extreme care should be taken to prevent it from harming organisms and the environment.
    Future Prospects
    P-Bromoiodobenzene is 1-Bromo-4-Iodobenzene, and it is also a chemical product. In today's world, science and technology are improving, and we have not dared to relax in our research and development of this product.
    How wonderful it can be for its future prospects. First, it can be used in new research. Today's research and development of materials, striving for refinement and effectiveness, this compound is very special, and it may become the foundation of new materials, eliminating diseases and saving people. Second, in the field of materials science, it is also expected to be more colorful. It may be able to synthesize high-performance materials and give new properties to materials, such as better performance and mechanical properties.
    However, if you want to achieve its unseen prosperity, there are many things to be broken. The method of synthesis needs to be more efficient, reliable, reduce its cost, and improve its efficiency. And the exploration of its nature still needs to be in-depth, and it needs to be clear that it can be transformed and reversed before it can be used well. In this way, P-Bromoiodobenzene can be used for the benefit of the world.
    Historical Development
    I have tried to study the substance of P-Bromoiodobenzene (that is, 1-Bromo-4-Iodobenzene). This substance is gradually becoming more and more important in the field of chemistry.
    In the past, chemical sages explored the properties and changes of substances, and they mostly studied halogenated aromatics. When P-Bromoiodobenzene first appeared, people were not very clear about its structure and properties. However, the public was unremitting, taking experiments as the path, reasoning as the boat, and gradually revealing its secrets.
    At the beginning, the synthesis method was still simple and crude, and the yield was quite low. After several generations of tempering, new techniques emerged, the yield gradually increased, and the application was also wide. In the industry of organic synthesis, it is a key raw material, contributing to the formation of many complex and delicate molecules. Looking at its historical evolution, it is like a star gradually shining, from the tiny to the glow, leaving a deep imprint on the development of chemistry, opening up new paths for future research and leading to the exploration of scholars.
    Product Overview
    Product Overview
    P-Bromoiodobenzene, also known as 1-Bromo-4-Iodobenzene, is a crucial raw material in the field of organic synthesis. This compound appears as a colorless to pale yellow liquid and plays a key role in many organic reactions.
    Structurally, above its benzene ring, bromine (Br) and iodine (I) occupy the opposite position, and the unique structure endows it with special chemical activity. The presence of bromine and iodine gives the compound both the reaction characteristics of bromine and the activity of iodine, providing rich possibilities for the design of organic synthesis routes.
    In practical applications, P-Bromoiodobenzene is often used as a key intermediate to participate in coupling reactions, such as Suzuki coupling, Stille coupling, etc., to construct carbon-carbon bonds and facilitate the synthesis of complex organic molecules. With its unique chemical properties, it can effectively improve reaction efficiency and selectivity, and is widely used in cutting-edge fields such as pharmaceutical chemistry and materials science. It is an important cornerstone for the development of organic synthetic chemistry.
    Physical & Chemical Properties
    P-Bromoiodobenzene (1-Bromo-4-Iodobenzene) is also an organic compound. Its state is mostly crystalline solid at room temperature, and its color is nearly colorless to slightly yellow, with a certain volatility. Looking at its melting point, it is about 40 to 43 degrees Celsius. This property is crucial when separating and purifying. The boiling point is roughly 219 to 221 degrees Celsius, indicating that it can be converted into a gaseous state at a specific temperature.
    When it comes to solubility, the substance is insoluble in water, but it exhibits good solubility in common organic solvents such as ethanol, ether, and benzene. This property makes it possible to use a suitable organic solvent as a reaction medium in organic synthesis reactions. The bromine and iodine atoms on the benzene ring can participate in many nucleophilic substitution reactions, metal catalytic coupling reactions, etc., and are widely used in the fields of medicine and material synthesis. Therefore, the physical and chemical properties of P-Bromoiodobenzene, such as physical state, melting point, solubility and chemical activity, endow it with an important position in organic chemistry research and industrial production.
    Technical Specifications & Labeling
    For P-Bromoiodobenzene, that is, 1-Bromo-4-Iodobenzene, the quality of the manufacturing technology should be determined. The quality of the technology should be clear. The quality of the raw materials, such as bromide, iodide, etc., must be determined. If the quality is high or low, the quality and efficiency of the product are affected by it.
    As for the quality (commodity quality), in addition to the chemical formula and molecular weight, the color and shape of the external product should also be clear. And the value of the quality must be obtained by the method of refinement and shown to people. The quality and content of the product cannot be ignored either. These are all elements that determine the quality of the product. Only by clarifying the technical quality and the quality (of the product) can the product be suitable for the needs and used for general production or production.
    Preparation Method
    In order to prepare P-Bromoiodobenzene (1-Bromo-4-Iodobenzene), the preparation method should be investigated in detail.
    In terms of raw materials, select the appropriate halogenated aromatic hydrocarbon as the starting material. The preparation process first reacts the halogenated aromatic hydrocarbon with a specific reagent at a suitable temperature and pressure. In the reaction step, the nucleophilic substitution reaction is first used, and one of the bromine atoms or iodine atoms is introduced to precisely regulate the reaction conditions, such as reaction time, temperature, and solvent type, in order to promote the reaction to proceed in the desired direction.
    The catalytic mechanism is also critical. The selection of high-efficiency catalysts can reduce the activation energy of the reaction, accelerate the reaction process, and improve the yield and purity of the product. In the reaction system, the amount and activity of the catalyst must be carefully controlled to stabilize the catalytic activity and ensure that the preparation process is efficient and controllable, so that high-quality P-Bromoiodobenzene can be prepared.
    Chemical Reactions & Modifications
    Taste the field of chemistry, explore endless, material changes, interesting. In today's words, P-Bromoiodobenzene is 1-Bromo-4-Iodobenzene, and its chemical reaction and modification are worthy of in-depth study.
    In past research, the reaction of such halogenated aromatic hydrocarbons often follows the path of nucleophilic substitution. The nucleophilic reagent attacks the benzene ring, and the halogen atoms leave to form new compounds. However, this reaction may encounter obstacles, such as the difference in electron cloud density of the benzene ring and the difference in the activity of the halogen atoms, which can make the reaction difficult.
    In order to improve, the researchers worked hard. Or choose a special catalyst to increase the reaction activity; or adjust the reaction conditions and control the reaction rate. After many attempts, there are metal catalysts that can promote the selective removal of halogen atoms and make the reaction follow the expected direction. There are also ligand modifiers that optimize the performance of the catalyst and improve the purity of the product.
    The modification of these substances is related to many fields of chemical industry, such as material synthesis and drug research and development. Make good use of its reaction characteristics and change its properties to suit the needs. In the future, it can be expected to contribute to the progress of chemistry and benefit the world.
    Synonyms & Product Names
    In the field of chemistry, there is a thing called P-Bromoiodobenzene, also known as 1-Bromo-4-Iodobenzene. This thing is a genus of organic halides. Although their names are different, they actually refer to the same thing. Chemists have studied it a lot in order to clarify its nature and its use.
    P-Bromoiodobenzene is called, according to its atomic arrangement and functional group position, in order to accurately describe its structure. And 1-Bromo-4-Iodobenzene, which is also based on the chemical naming convention, shows the position of bromine and iodine in the benzene ring. Although the names are different, they all refer to the compounds of bromine and iodine in the benzene ring.
    This substance is often used as an essential agent in organic synthesis. Because of its halogen atom, it can lead to reactions and produce a variety of products. Chemists use it as a basis to explore new ways and innovations in the laboratory, hoping to make progress and benefit the world.
    Safety & Operational Standards
    About P - Bromoiodobenzene; 1 - Bromo - 4 - Iodobenzene Product Safety and Operation Specifications
    P - Bromoiodobenzene, also known as 1 - Bromo - 4 - Iodobenzene, is a common chemical in chemical research. During its experimental operation and use, safety and standardization are of the utmost importance.
    First word safety. This chemical may be toxic and irritating, and it can cause damage to the human body if it touches the skin, inhales its vapor, or is accidentally ingested. Therefore, when operating, be sure to be fully armed, wear laboratory clothes, protective gloves and goggles to prevent direct contact with the body. And the operation should be carried out in a well-ventilated experimental environment, preferably in a fume hood to disperse the harmful steam that may be generated and avoid inhalation into the body.
    The second discussion on the operating specifications. When using the chemical, use clean and suitable equipment, and operate according to the accurate measurement requirements. Do not take too much abuse, resulting in waste of resources and environmental pollution. The weighing process must be rigorous, and accurate weighing instruments should be used to ensure that the dosage is correct. When mixing or reacting, the reaction conditions and steps should be followed step by step, and the reaction parameters should not be changed at will to avoid accidental reactions. After the reaction is completed, the remaining P-Bromoiodobenzene should not be discarded at will, and should be properly disposed of according to the waste treatment process stipulated by the laboratory to prevent harm to the environment.
    In short, in the use and research of P-Bromoiodobenzene, strict adherence to safety and operating standards can achieve the purpose of the experiment, and also ensure the safety of the experimental personnel and the cleanliness of the environment.
    Application Area
    P-Bromoiodobenzene, that is, 1 - Bromo - 4 - Iodobenzene, has a wide range of application fields. In the field of organic synthesis, it is often used as a key intermediate. Because of its benzene ring, bromine and iodine difunctional groups coexist and have unique properties. It can be introduced into other functional groups or carbon chains by many chemical reactions, such as coupling reactions, to build complex organic molecular structures.
    In the field of materials science, it may be used to prepare materials with special photoelectric properties. After appropriate chemical modification, the material exhibits unique light absorption, electrical conductivity and other properties, and is used in the research and development of devices such as organic Light Emitting Diodes and solar cells.
    In the field of medicinal chemistry, this is the starting material, which can synthesize compounds with specific biological activities. After pharmacological research and screening, it may be expected to become new drugs. Its unique chemical structure provides different ideas for drug molecular design and promotes the development of new drugs.
    Research & Development
    I am interested in chemical substances, and I always have the heart to study them. Recently, I have been focusing on the substance P-Bromoiodobenzene (1-Bromo-4-Iodobenzene).
    At the beginning, I studied its properties in detail and explored the wonders of its structure. After many experiments, I observed its reaction. This substance seems to have extraordinary potential in the field of organic synthesis.
    In order to gain in-depth insight, it is prepared by different methods. Or change the conditions of the reaction, or use the reagents easily, hoping for better results. Every change is recorded in detail.
    On the way to study, despite many obstacles, my heart is as solid as a rock. With unremitting efforts, the application of this substance can be expanded, contributing to the development of chemistry, and opening up new paths for future generations, which is beneficial.
    Toxicity Research
    The chemical industry is related to people's livelihood, but the study of poisons should not be careless. Today there is a substance called P-Bromoiodobenzene, or 1-Bromo-4-Iodobenzene, and the study of its toxicity is quite important.
    This substance may also be used in the chemical process. However, the test of toxicity should be checked when it enters the body, or by breathing, or through the skin, or due to diet. After entering the body, the organs and physiological changes involved are all important to investigate.
    The test of toxicity is often based on animals to observe the differences in symptoms and physiological indicators. It is also necessary to consider the impact of its environment, such as temperature, humidity, light, etc. After various studies, it is clear that its toxicity and strength can be used as a basis for protection and application, so that workers can be safe and the environment is peaceful, and poisons should not be a disaster to the world.
    Future Prospects
    P-Bromoiodobenzene, that is, 1-Bromo-4-Iodobenzene, is a hidden treasure in the field of chemistry, waiting for our generation to explore. Although it is not yet prosperous at the moment, the future prospects can be looked forward to.
    The road of chemical research is often small and vast. Although P-Bromoiodobenzene is not well known to the public, its structure is unique, or it can be a new path in the art of organic synthesis. With time, it can be used to create new drugs to solve the ills of all living beings; or to help material innovation and make the equipment more sophisticated.
    And the progress of science is like sailing against the current, if you don't advance, you will retreat. Those of us who study chemistry should study this object with tenacity. We hope that in the future, we can use its characteristics to contribute to the development of the world and the benefit of people's livelihood. In this way, the prospect of P-Bromoiodobenzene will be like the rising sun, shining brightly, in the unfinished scientific journey, and it will become the unfinished ambition of our generation.
    Where to Buy P-Bromoiodobenzene; 1-Bromo-4-Iodobenzene in China?
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    Frequently Asked Questions

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    P-bromoiodobenzene; what is the Chinese name of 1-bromo-4-iodobenzene
    The Chinese name for P-bromoiodobenzene and 1-bromo-4-iodobenzene is bromoiodobenzene.
    The naming of this compound follows the naming of the compound. In the naming of benzene derivatives, if there are different substituents on the benzene, the main group of the substituent can be determined first, and the carbon position where it is located is 1, and then the other substituent position is minimized in sequence. In this example, bromine (bromo) and iodo (iodo) are used as substituents, bromine is located in the carbon position of 1, iodine is located in the 4 position, and bromine is listed first according to the letter of the substituent, and iodine is listed first, hence the name 1-bromo-4-iodobenzene. Because bromine and iodine are located in the benzene position, they are also bromoiodobenzene. Bromoiodobenzene is important in the field of synthesis, and can be used in the field of synthesis. It can be used in more important molecules. Its chemical properties are affected by the shadow of bromine and iodine atoms. All of them have certain activities, such as nuclear substitution, even and other polymers. Synthesizers provide an effective way to build specific compounds.
    P-bromoiodobenzene; what are the physical properties of 1-bromo-4-iodobenzene
    P-bromoiodobenzene (1-bromo-4-iodobenzene) is an organic compound, and its physical properties are worth exploring.
    Looking at its properties, it is mostly solid at room temperature. Due to the existence of van der Waals forces between molecules, its aggregation state is stable. Its melting and boiling point is closely related to the molecular structure. The bromine and iodine atoms are arranged in the phenyl ring, and the molecular symmetry is good. The intermolecular force is regular, and the melting and boiling point is relatively considerable.
    Furthermore, its solubility also has characteristics. This compound is insoluble in water, because water is a polar solvent, while P-bromoiodobenzene is a non-polar or weakly polar molecule. According to the principle of "similar miscibility", the two are insoluble. However, in organic solvents, such as benzene, carbon tetrachloride and other non-polar or weakly polar organic solvents, it has good solubility, because the intermolecular force is similar to that of organic solvents, and it can be dispersed and mixed with each other.
    In addition, the density of P-bromoiodobenzene cannot be ignored. Due to the relatively large atomic mass of bromine and iodine atoms, its density is usually greater than that of water, which is crucial when it comes to operations such as liquid-liquid separation.
    As for its color, pure P-bromoiodobenzene is almost colorless, but due to factors such as impurities or storage conditions, it may show a slightly yellowish color.
    In summary, the physical properties of P-bromoiodobenzene, such as solid-state properties, specific solubility, high density, and near-colorless properties, are of great significance in organic synthesis, chemical production, and other fields, affecting related operations and reaction processes.
    P-bromoiodobenzene; what are the chemical properties of 1-bromo-4-iodobenzene
    P-bromoiodobenzene (1-bromo-4-iodobenzene) is an organic compound with unique chemical properties.
    First, the aromatic electrophilic substitution reaction, because the benzene ring has an electron cloud, can attract electrophilic reagents. Taking the bromination reaction as an example, the electrophilic reagent bromine cation will attack the benzene ring. Because both bromine and iodine are ortho-para-sites, new substituents are introduced into the ortho-site or para-site of bromine or iodine. In case of a mixture of nitric acid and sulfuric acid, a nitration reaction occurs, and the nitro group also tends to enter the ortho-site of bromine or iodine.
    Second, the reactivity of halogenated aromatic hydrocarbons. Although the benzene ring makes the halogen atom less active than the halogenated alkane, its bromine and iodine In the presence of appropriate metal catalysts (such as palladium catalysts) and ligands, coupling reactions can occur with organometallic reagents, such as reactions with Grignard reagents, which can form new carbon-carbon bonds and construct more complex organic molecular structures.
    Third, in terms of physical properties, this compound is usually a solid with a certain melting point and boiling point. Due to the difference in the electronegativity of bromine and iodine atoms in the molecule, the molecule has a certain polarity, which affects its solubility in different solvents. Generally, it has better solubility in organic solvents such as dichloromethane and chloroform, but poor solubility in water.
    P-bromoiodobenzene; what is the main use of 1-bromo-4-iodobenzene
    P-bromoiodobenzene is 1-bromo-4-iodobenzene, Chinese name 1-bromo-4-iodobenzene. This substance has a wide range of uses and is a key raw material in the field of organic synthesis.
    In the process of organic synthesis, 1-bromo-4-iodobenzene is often the cornerstone of building complex organic molecules. On its benzene ring, both bromine and iodine atoms have active chemical properties, and various organic compounds can be derived through many chemical reactions, such as nucleophilic substitution reactions, and various nucleophilic reagents. For example, when it interacts with reagents containing nucleophilic groups such as nitrogen, oxygen, and sulfur, it can form carbon-heteroatomic bonds, laying the foundation for the creation of new drugs and materials.
    In the field of pharmaceutical chemistry, 1-bromo-4-iodobenzene also plays an important role. Synthesis of many drug molecules, using this as the starting material. Due to its unique structure, chemically modified drugs can impart specific physiological activities and pharmacokinetic properties. By adjusting the type, position and quantity of substituents on the benzene ring, the interaction between drugs and targets can be optimized, and the efficacy and selectivity of drugs can be improved.
    In the field of materials science, 1-bromo-4-iodobenzene can participate in the preparation of functional materials. For example, through polymerization or copolymerization with other functional monomers, polymer materials with special photoelectric properties can be prepared, which have potential applications in electronic devices, optical materials, etc., such as organic Light Emitting Diode (OLED), solar cells and other devices.
    Furthermore, 1-bromo-4-iodobenzene can be used in the field of organometallic chemistry as a ligand or substrate, and can cooperate with metal catalysts to realize various catalytic reactions and promote the development and innovation of organic synthesis methods. Overall, 1-bromo-4-iodobenzene has important uses in many fields due to its unique structure and reactivity, promoting the development of chemical science and related industries.
    P-bromoiodobenzene; what are the synthesis methods of 1-bromo-4-iodobenzene
    To prepare p-bromoiodobenzene (1-bromo-4-iodobenzene), there are two common methods.
    First, benzene is used as the starting material. First, benzene and bromine are substituted under the catalysis of iron tribromide to obtain bromobenzene. In this reaction, bromine atoms replace hydrogen atoms on the benzene ring. Because bromine is an ortho-para-locator, the products are mainly o-bromobenzene and p-bromobenzene, which can be separated to obtain pure p-bromobenzene. Subsequently, p-bromobenzene reacts with iodine in the presence of an appropriate oxidant (such as nitric acid, etc.). The role of the oxidant is to change the iodine into a more active iodine Because bromine has occupied one place in the benzene ring, the iodine atom mainly replaces its para-hydrogen atom to obtain p-bromoiodobenzene.
    Second, p-aminobenzene sulfonic acid is used as the starting material. The p-aminobenzene sulfonic acid is first diazotized, that is, at low temperature and under the action of sodium nitrite and hydrochloric acid, the amino group is converted into a diazonium salt. The diazonium salt is active and can undergo a Sandmeier reaction with halides such as potassium bromide and potassium iodide. First, it reacts with potassium bromide, and the diazonium group is replaced by the bromine atom to obtain p-bromobenzene sulfonic acid. Then, the p-bromobenzene sulfonic acid is hydrolyzed to remove the sulfonic acid group to obtain p-bromobenzene. Finally, the reaction of
    The above two methods have their own advantages and disadvantages. The former step is relatively simple, but the separation is difficult; although the latter step is complicated, the product purity is excellent. In actual synthesis, the appropriate method should be selected according to specific needs and conditions.