P Bromoiodobenzene
Iodobenzene

P-Bromoiodobenzene

Fengxi Chemical

Specifications

HS Code

344395

Chemical Formula C6H4BrI
Molar Mass 282.804 g/mol
Appearance Colorless to pale yellow solid
Melting Point 42 - 44 °C
Boiling Point 256 - 258 °C
Density 2.186 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ether, benzene
Odor Faint, characteristic odor
Stability Stable under normal conditions, but light - sensitive

As an accredited P-Bromoiodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of P - bromoiodobenzene packaged in a sealed glass bottle.
Storage P - bromoiodobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. It should be kept in a tightly sealed container to prevent exposure to air and moisture. Due to its potential reactivity and toxicity, store it separately from incompatible substances like oxidizing agents. Label the storage container clearly for easy identification and safety.
Shipping P - bromoiodobenzene is shipped in well - sealed, corrosion - resistant containers. Shipment follows strict chemical transport regulations, ensuring proper handling to prevent spills and exposure during transit.
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P-Bromoiodobenzene
General Information
Historical Development
P-Bromoiodobenzene is also an organic compound. The method of its preparation has undergone changes. In the past, the synthesis technique was not refined, and the yield was quite low. However, scholars worked tirelessly, and with the passage of time, their skills gradually improved.
At the beginning, I tried various halogenation reactions, and the conditions were harsh and the side reactions were frequent. After repeated experiments, the reaction steps were optimized, the reagents used were improved, and the method was gradually obtained. In recent times, the application of new catalytic systems has made the synthesis of P-Bromoiodobenzene more efficient and convenient.
It is widely used in the field of organic synthesis and is a key intermediate for the preparation of many complex compounds. The products derived from it have made important contributions to medicine, materials and other aspects. The historical evolution of P-Bromoiodobenzene is a testament to the continuous progress and breakthroughs in chemical research.
Product Overview
P-Bromoiodobenzene is also an organic compound. Its shape is a colorless to light yellow liquid with a special odor. The structure of this compound is above the benzene ring, where the bromine atom is opposed to the iodine atom.
P-Bromoiodobenzene is widely used in the field of organic synthesis. It is often an intermediary for the preparation of complex organic molecules. With the activity of its halogen atom, it can initiate a variety of chemical reactions. For example, through nucleophilic substitution, various functional groups can be introduced to expand the structure and function of the molecule.
The method of preparing P-Bromoiodobenzene is commonly obtained by using benzene as the starting material and by bromination, iodization and other steps. The control of reaction conditions is crucial, and factors such as temperature and reagent ratio will affect the purity and yield of the product.
From this perspective, although P-Bromoiodobenzene is a small organic molecule, it plays an important role in the process of organic chemical synthesis and is related to the basic construction of many fine chemicals and drug development.
Physical & Chemical Properties
P-Bromoiodobenzene is an organic compound with unique physical and chemical properties. Looking at its physical properties, it is a solid state at room temperature, and its color is nearly colorless to yellowish, which is due to the orderly arrangement of its molecular structure. Its melting point and boiling point also have specific values. The melting point is about [specific melting point value], and the boiling point is around [specific boiling point value], which is determined by the intermolecular force.
In terms of chemical properties, the bromine and iodine atoms in P-Bromoiodobenzene are highly active. The bromine atom has strong electronegativity and the iodine atom has a large radius, which makes the compound special in nucleophilic substitution reactions. It can react with a variety of nucleophilic reagents, such as with sodium alcohol, and can generate corresponding ether products. This is due to the fact that the halogen atom on the benzene ring is affected by the electron cloud of the benzene ring and is easily attacked by nucleophiles, which shows unique chemical activity and is widely used in the field of organic synthesis.
Technical Specifications & Labeling
The process specifications and identification (product parameters) of this product of P-Bromoiodobenzene are the key. The process specifications are related to the selection of raw materials, and the pure quality must be selected, and the impurities must be fine. The reaction conditions, temperature and pressure are fixed, the temperature is controlled in a certain range, and the pressure is also appropriate, in order to promote the forward reaction and obtain high-purity products.
In terms of identification (product parameters), the appearance and color should be uniform, and there should be no variegation or foreign matter. The purity must reach a specific standard, and the accurate detection should not be tolerated at all. The amount of impurities contained, list their types and proportions in detail, so as to clarify their quality. In this way, the complete process specifications and identification (product parameters) can ensure the quality of P-Bromoiodobenzene, and have a reliable foundation for both practical and research.
Preparation Method
It is very important to choose the raw material and preparation method of P-Bromoiodobenzene. This product can be obtained by taking iodobenzene as the raw material, supplemented by brominating reagents, and brominating technology.
The method is as follows: Prepare an appropriate amount of iodobenzene first and place it in a clean reaction vessel. Then add brominating reagents, such as liquid bromine and an appropriate amount of catalyst, such as iron powder. Control the temperature in a suitable range, about room temperature to 50 degrees Celsius, and stir slowly to make it fully react.
When the reaction is taking place, watch it closely, and stop when the reaction signs reach the expected level. The subsequent steps of separation and purification. Pure P-Bromoiodobenzene is obtained by extraction with suitable solvent, distillation, recrystallization and other techniques to remove impurities. Among them, the control of reaction conditions and the adjustment of the proportion of raw materials all affect the quality and quantity of the product. It needs to be handled with caution to obtain good results.
Chemical Reactions & Modifications
P-Bromoiodobenzene is also an organic compound. The reaction of its preparation has been studied by chemists. In the past, this compound was often prepared by a certain method, but the method was not good, the reaction rate was not high, and the by-products were complex, making purification difficult.
Today's chemists strive to improve. After many experiments, the influence of different reaction conditions, such as temperature, solvent, catalyst, etc. There are new catalytic systems, which greatly increase the selectivity of the reaction, reduce the side reactions, and increase the yield.
In the study of the reaction mechanism, there are also advances. Understanding the process of each step in the reaction and the wonderful interaction between molecules allows for more precise control of the reaction. Therefore, the synthesis method of P-Bromoiodobenzene has been gradually perfected, adding new color to the field of organic synthesis, and is widely used in medicine, materials and other industries.
Synonyms & Product Names
P - Bromoiodobenzene is also a chemical substance. Its name is also the same. Or bromoiodobenzene, which is named according to its position. In other words, it refers to the position of bromoiodobenzene in the phase of benzene.
To its trade name, it may be used in the market. However, they all refer to the same chemical substance. It is used in chemical research and engineering. There can be synthetic raw materials, and there are many processes.
Our chemical researchers explore its properties and laws of inversion, and strive to make good use of this compound to expand the new frontier of the chemical field. Deeply knowing the identity of its same name and trade name, and also researching one of the key issues, can help us to investigate and communicate in the text, understand it, and develop it more conveniently.
Safety & Operational Standards
P-Bromoiodobenzene is an important chemical in organic synthesis. In order to ensure the safety of production and use, it is essential to follow strict safety and operating practices.
When preparing P-Bromoiodobenzene, it is necessary to operate in a well-ventilated experimental environment. Operators must wear appropriate protective equipment, such as laboratory clothes, gloves and goggles, to prevent direct contact of chemicals with the body.
When taking raw materials and operating reactions, strictly follow established procedures. The amount of bromine and iodine is accurately weighed, the reaction system is added in a specific order, and the reaction temperature and time are closely monitored. Due to the reaction process or the generation of heat and gas, it is necessary to pay attention to the pressure and exhaust conditions of the reaction device to prevent danger caused by excessive pressure.
After the reaction is completed, the separation and purification of the product should also be handled with caution. Appropriate separation methods, such as extraction, distillation, etc., should be used, and temperature and pressure control should be paid attention to during operation to avoid product loss or safety accidents.
When storing P-Bromoiodobenzene, it should be placed in a cool, dry and ventilated place, away from ignition and oxidants. Storage containers should be well sealed to prevent leakage. And clearly label the chemical name, hazardous characteristics and other information on the container.
When using P-Bromoiodobenzene for subsequent reactions, safety procedures should also be followed. After the experiment is completed, properly dispose of the remaining chemicals and waste, and do not dump them at will to prevent pollution to the environment.
Only by strictly adhering to safety and operating standards can we ensure the safe and orderly conduct of P-Bromoiodobenzene-related experiments and production activities, while ensuring that personnel safety and the environment are not endangered.
Application Area
P-Bromoiodobenzene is also an organic compound. Its application field is quite wide. In the field of pharmaceutical synthesis, it is often a key intermediate. With its unique structure, it can undergo many chemical reactions to build complex drug molecular structures, help the development of new drugs, or cure various diseases.
In the field of materials science, it also has important functions. It can participate in the synthesis of polymer materials, giving materials special electrical and optical properties, such as the preparation of photoelectric conversion materials, or can be applied to solar cells to improve their photoelectric conversion efficiency.
In the field of organic synthesis chemistry, it is an important building block for the construction of various organic compounds. Chemists use their reactivity to ingeniously design reaction paths, create a variety of organic molecules, and promote the progress of organic synthetic chemistry. Therefore, P-Bromoiodobenzene plays an indispensable role in various application fields.
Research & Development
Yu Taste is dedicated to the research of P-Bromoiodobenzene. This compound has a unique structure and has great potential in the field of organic synthesis.
At the beginning, to explore its synthesis path, many attempts have encountered obstacles. The choice of raw materials and the control of reaction conditions are all difficult problems. However, unremitting research has resulted in the end. With a specific halogenation reaction, adjusting the temperature and catalyst dosage, the yield can gradually be improved.
And studying its properties, it was found that it has special performance in nucleophilic substitution reactions, and can be cleverly combined with a variety of reagents to derive new compounds. This property paves a new way for the development of organic materials.
Looking to the future, P-Bromoiodobenzene is expected to shine in drug synthesis, photoelectric material preparation and other aspects. I will continue to study and explore its potential, so as to promote it from the laboratory to practical use and contribute to the development of chemistry.
Toxicity Research
Taste the industry of chemistry, and explore the physical properties are the most important. Looking at P-Bromoiodobenzene today, the study of its toxicity is related to everyone's well-being, and it is also an important task for our chemical researchers.
P-Bromoiodobenzene, the appearance may be different. After experiments, it has been observed that it causes toxic changes in a specific environment or in phase with other substances. After many investigations, if this substance is not carefully entered into the body, it may disturb the order of physiology. Or harm the viscera, or disrupt nerve conduction, which cannot be ignored.
Our researchers, with a rigorous state, use various methods to analyze the mechanism of its toxicity. Or observe its change at the cellular level, or explore its cause from the molecular perspective. The true meaning of hope is to protect and use it well, reduce its harm to the invisible, protect everyone's health, and promote the steady progress of the chemical industry, so as not to make toxic things a disaster to the world.
Future Prospects
I tried to study P-Bromoiodobenzene, and I thought about its future prospects. P-Bromoiodobenzene is also an important agent in organic synthesis. Looking at the current situation, science and technology are advancing, and it will be more widely used in medical chemistry, materials science and other fields.
In medical chemistry, it may help to create new drugs. Its unique structure may be precisely combined with biological targets to develop special and good drugs to treat diseases and diseases for the world. In materials science, it is expected to give birth to novel materials with novel functions, or with special photoelectric properties, for high-end electronic devices, making the devices more delicate and efficient.
I believe that with time, researchers will be able to explore the potential of P-Bromoiodobenzene, open up new frontiers, and contribute to human well-being, so that its future development will be brilliant and promising.
Where to Buy P-Bromoiodobenzene in China?
As a trusted P-Bromoiodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading P-Bromoiodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the chemical structure of P-bromoiodobenzene?
P-bromoiodobenzene is also a compound. Its chemical reaction is based on benzene, which is divided into bromine (Br) and iodine (I) atoms at the para-position (P) of benzene. Benzene is a planar hexadic atom formed by six carbon atoms in a common form, which is highly qualitative. Its carbon atoms are mixed into the p-domain by sp ², and each carbon atom has only one unmixed p-domain. These p-domains are repeated in parallel with each other to form the p-domain of the p-domain, which gives the special chemical properties of benzene. In this compound, the bromine atom and the iodine atom are divided into the benzene-domain. The bromine atom, whose outer nucleus arrangement makes it easy to obtain ions in the reaction, has a certain degree of resistance. The iodine atom is also the same, and the resistance is slightly lower than that of bromine, but it can also change the reaction of benzene. These two are located at the benzene position, so that the electron cloud on the benzene can be changed, which affects the physical resistance of the compound, such as resistance, melting boiling, reaction activity, etc. And due to the empty resistance and reaction effect of the bromine-iodine atom, this compound has the reaction characteristics in the synthesis and other fields.
What are the main physical properties of P-bromoiodobenzene?
P-bromoiodobenzene, or p-bromoiodobenzene, is an organic compound with many important physical properties. Its appearance is colorless to pale yellow crystal or powder, which is stable at room temperature and pressure. The melting point is at 40-43 ° C, which makes p-bromoiodobenzene melt from solid to liquid. With this melting point characteristic, the melting point measurement can be used as a key indicator when separating, purifying or identifying p-bromoiodobenzene. The boiling point is about 254 ° C. At this temperature, p-bromoiodobenzene changes from liquid to gaseous. The existence of the boiling point determines its phase change under specific temperature conditions and plays an important role in separation operations such as distillation. p-Bromoiodobenzene is insoluble in water, but it is soluble in organic solvents such as ethanol, ether, and benzene. This solubility is due to the non-polar nature of its molecular structure, which is quite different from the polarity of water molecules. According to the principle of "similar miscibility", it is more likely to be miscible with non-polar organic solvents. This solubility is helpful in the selection of suitable solvents for reaction, separation, and purification in organic synthesis. The density of p-bromoiodobenzene is greater than that of water. When it involves liquid-liquid separation operations such as stratification, its location is different from that of water, which is conducive to separation by means of liquid p-bromoiodobenzene also has a certain volatility. Although the volatility is not strong, long-term exposure to air will reduce its quality due to volatilization. During storage and use, attention should be paid to sealed storage to prevent volatilization loss and ensure the stability of its chemical properties and content. The above physical properties are interrelated and affect each other, which profoundly affects the application and operation of p-bromoiodobenzene in organic synthesis, chemical analysis and other fields.
What are the common applications of P-bromoiodobenzene in organic synthesis?
P-bromoiodobenzene is a common raw material in organic synthesis and has a wide range of uses. First, P-bromoiodobenzene can be used as a substrate in the coupling reaction of halogenated aromatics. Take Suzuki coupling reaction as an example, it can form biphenyl compounds with aryl boric acid under the action of palladium catalyst and base. This reaction has mild conditions and good selectivity, and is widely used in drug synthesis and materials science. For example, when synthesizing new organic optoelectronic materials, a conjugated system with a specific structure can be constructed by this reaction to improve the photoelectric properties of the materials. Second, in metal-catalyzed cross-coupling reactions, such as Negishi coupling reactions, P-bromoiodobenzene and organozinc reagents can form carbon-carbon bonds under the action of nickel or palladium catalysts. This reaction provides an effective way to construct complex organic molecular structures, which is of great significance in the total synthesis of natural products, and can assist in the synthesis of natural product molecules with specific biological activities. Third, P-bromoiodobenzene can be used to prepare functional materials. Because its molecules contain both bromine and iodine atoms, different functional groups can be introduced through subsequent reactions to prepare polymers and liquid crystal materials with special properties. For example, the preparation of polymer materials with specific solubility and thermal stability has potential applications in the field of coatings and adhesives. Fourth, in the design of organic synthesis routes, P-bromoiodobenzene can be reacted in steps due to the different activities of two halogen atoms, which provides convenience for the synthesis of complex aromatic derivatives with specific substitution patterns. First, the selective reaction is carried out by taking advantage of the high activity of iodine atoms, and then the bromine atoms are converted to accurately construct the target molecular structure.
What are the preparation methods of P-bromoiodobenzene?
P-bromoiodobenzene (P-bromoiodobenzene) is also an organic compound. The preparation method has the following numbers. First, benzene is used as the starting material and is first brominated. Benzene and bromine can be obtained under the action of catalysts such as iron bromide. The chemical equation of this reaction is:\ (C_ {6} H_ {6} + Br_ {2}\ xrightarrow [] {FeBr_ {3}} C_ {6} H_ {5} Br + HBr\). Then, under appropriate conditions, such as copper powder as the catalyst, the reaction of bromoiodobenzene and iodine can be heated to obtain P-bromoiodobenzene. The chemical equation is:\ (C_ {6} H_ {5} Br + I_ {2}\ xrightarrow [] {Cu} C_ {6} H_ {4} BrI + HI\). Second, the reaction of diazonium salt can be used. First, aniline is made into diazonium salt by diazotization reaction. Aniline and nitrous acid under low temperature and the presence of hydrochloric acid, the chemical equation is:\ (C_ {6} H_ {5} NH_ {2} + HNO_ {2} + HCl\ xrightarrow [] {0 - 5 ^ {\ circ} C} C_ {6} H_ {5} N_ {2} Cl + 2H_ {2} O\). Then, the diazonium salt is reacted with the mixed solution of potassium bromide and potassium iodide, and the diazonium group is replaced by the bromine atom and the iodine atom to obtain P-bromoiodobenzene. Third, phenol is used as raw material. Phenol is first brominated to obtain bromophenol, and then the hydroxyl group is converted to the diazonium group, and then reacted with potassium iodide to introduce iodine atoms. After appropriate reaction steps and conditions are controlled, P-bromoiodobenzene can also be obtained. When preparing P-bromoiodobenzene, it is necessary to pay attention to the reaction conditions, such as temperature, catalyst type and dosage, which have a significant impact on the yield of the reaction and the purity of And each reaction step needs to be properly handled to achieve a good preparation effect.
What are the storage conditions for P-bromoiodobenzene?
P-bromoiodobenzene is also an organic compound. Its storage conditions are crucial, related to its quality and stability. This substance should be stored in a cool and ventilated warehouse. Because of the cool place, it can reduce the risk of decomposition and deterioration due to excessive temperature. Well ventilated, it can avoid the accumulation of gas and avoid safety. And keep away from fire and heat sources. Both fire and heat sources can cause combustion or explosion, which is a serious harm. The temperature of the warehouse should be controlled within a reasonable range, not too high or too low. Too high can easily promote its chemical reaction, and too low may cause its physical state to change, affecting its properties. At the same time, it should be stored separately from oxidants, acids, alkalis, etc., and should not be mixed. P-bromoiodobenzene and other such substances may react chemically, causing danger. When storing, also pay attention to the integrity of the package. If the package is damaged, it may come into contact with the external environment and react, which will damage its quality. And it needs to be checked regularly to see if there are any abnormal changes. If so, it should be disposed of in time. When handling, it should be handled lightly to prevent damage to its packaging and containers. All these things, in order to properly store P-bromoiodobenzene, can ensure its safety and quality.