P-Iodobenzonitrile

Fengxi Chemical

Specifications

HS Code	694424
Chemical Formula	C7H4IN
Molar Mass	245.02 g/mol
Appearance	Solid
Melting Point	66 - 70 °C
Boiling Point	257.7 °C at 760 mmHg
Density	1.848 g/cm³
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, chloroform
Flash Point	109.7 °C
Stability	Stable under normal conditions, but may react with strong oxidizing agents

As an accredited P-Iodobenzonitrile factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	10 - gram vial of P - iodobenzonitrile, securely sealed in chemical - grade packaging.
Storage	P - iodobenzonitrile should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly closed container to prevent moisture and air exposure. Store it separately from oxidizing agents and incompatible substances. The storage conditions help maintain its chemical stability and minimize the risk of degradation or hazardous reactions.
Shipping	P - iodobenzonitrile is shipped in accordance with strict chemical transportation regulations. It's packaged securely in appropriate containers to prevent leakage, and transported by carriers licensed for handling hazardous chemicals.

Free Quote

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General Information

Historical Development

"The Historical Development of P-Iodobenzonitrile"
The author of P-Iodobenzonitrile is also a chemical substance. Looking back to the past, at the beginning of its research and development, chemists worked hard to analyze its properties and explore the method of synthesis. At the beginning, the understanding was still shallow, the road of synthesis was full of thorns, and many attempts were not complete.
However, with the passage of time and the advancement of science and technology, chemists continued to study and improve the synthesis process. From the crude method in the early days, it gradually became a precise and efficient road. Many scholars applied their own wisdom, either in the reaction conditions or in the selection of raw materials. Therefore, the synthesis of P-Iodobenzonitrile became more mature, the yield gradually increased, and the quality became better.
Looking at its historical development, it is actually the process of chemists' unremitting exploration, breakthrough and innovation, and has made outstanding contributions to the expansion of the chemical field.

Product Overview

P-Iodobenzonitrile is a crucial chemical in the field of organic synthesis. Its properties are white to light yellow crystalline powder with certain stability.
This compound is often used as a key intermediate in organic synthesis. Through a series of delicate chemical reactions, such as nucleophilic substitution, coupling reactions, etc., it can be ingeniously transformed to derive many organic molecules with unique structures and functions.
In the field of medicinal chemistry, P-Iodobenzonitrile may be the cornerstone of the creation of new drugs, helping to build complex drug molecular structures to meet the needs of fighting various diseases. In the field of materials science, it may also be able to construct organic materials with specific properties, such as optoelectronic materials, injecting new vitality into the development of this field. Overall, P-Iodobenzonitrile plays an indispensable role in the process of chemical research and related industries, with promising prospects.

Physical & Chemical Properties

P-Iodobenzonitrile is an organic compound. Its physical and chemical properties can be studied. Its color is often close to colorless, in a crystalline state, stable at room temperature. Its melting point is about a specific value, which depends on the strength of its intermolecular forces. Its solubility in organic solvents, such as alcohols and ethers, has a certain degree of performance, due to the characteristics of its molecular structure.
From the perspective of chemical properties, the presence of iodine atoms and cyano groups in P-Iodobenzonitrile gives it unique reactivity. Iodine atoms can participate in nucleophilic substitution reactions, while cyano groups can exhibit their chemical energy in many reactions, such as hydrolysis and addition. This compound is often an important intermediate in the field of organic synthesis, assisting chemists in constructing complex molecular structures to form various useful substances.

Technical Specifications & Labeling

Nowadays, there is P-Iodobenzonitrile. In industrial manufacturing, process specifications and identification (product parameters) are the key. Its process specifications, from the selection of raw materials, must choose the pure quality, and the impurities must be fine. The temperature and pressure of the reaction must also be precisely controlled. With suitable temperature and pressure, the reaction will be promoted, the yield will be improved, and the quality will be guaranteed.
In terms of identification, the product parameters are clearly stated. For example, the number of purity should be extremely high, and the impurity content should be carefully marked. Its properties, melting point, boiling point and other physical characteristics must also be clearly marked. In this way, the user can know its nature and understand its quality, and can make good use of it in various applications without error. The process specification and marking are accurate, ensuring the high quality and wide use of P-Iodobenzonitrile.

Preparation Method

The raw materials, production process, reaction steps and catalytic mechanism of this product of P-Iodobenzonitrile are the key.
Take iodobenzene and cuprous cyanide as raw materials, in a sealed kettle, with dimethylformamide as a solvent, heat to 150-160 ℃, this is the initial reaction step. The iodine atom of iodobenzene has good activity, and cuprous cyanide provides a cyanide group. The two interact and undergo nucleophilic substitution reaction. The catalytic mechanism is that dimethylformamide can stabilize the transition state, reduce the activation energy of the reaction, and promote the smooth progress of the reaction.
After the reaction is completed, cool the kettle body, wash the product with a dilute acid solution, and remove the unreacted cuprous cyanide and by-products. Pure P-Iodobenzonitrile was obtained by distillation under reduced pressure, separation of solvent and chromatography with silica gel column. During the whole preparation process, each step needs to be precisely controlled, and the proportion of raw materials, reaction temperature and time will affect the purity and yield of the product.

Chemical Reactions & Modifications

In recent years, P-Iodobenzonitrile has been studied in the chemical reaction and modification. The way of its reaction used to follow the old method, but the effect was not good.
Today's change is the first method of catalysis. The catalysis used in the past was not efficient, but now I am looking for a new type of catalysis, which can increase the reaction speed and the purity of the product.
Furthermore, the reaction environment has also been improved. The control of temperature and pressure is more accurate than in the past, which makes the reaction tend to be better. In the past, the rate of the product was low and there were many impurities. Now that it has been modified, the rate of the product has increased significantly and the impurities are also less.
In addition, the mechanism of the reaction has been studied in detail. Understanding the change of molecules and the shift of electrons provides evidence for the modification strategy. Through these changes, P-Iodobenzonitrile has benefited from the reaction and modification, and the future road can be expected to be wider.

Synonyms & Product Names

Today there is a chemical product called P-Iodobenzonitrile. Its synonyms and trade names are related to the logo of this product.
P-Iodobenzonitrile is a commonly used product in chemical research. In the academic world, its synonyms are the medium of scientific research communication, and scholars understand its meaning, which is convenient for discussing experimental details and results. The trade name is circulated in the market, used by merchants to promote this product, making it easy for customers to identify and choose.
Although synonyms and trade names are different, they all refer to P-Iodobenzonitrile. The two complement each other, synonyms help academic progress, and trade names promote business circulation. As chemical research continues to advance, the synonyms and trade names of P-Iodobenzonitrile will also change with in-depth research and market demand, continuously contributing to the development of the chemical field.

Safety & Operational Standards

P-Iodobenzonitrile Code for safe production and operation
P-Iodobenzonitrile is also a raw material commonly used in chemical preparation. Although its characteristics are unique, it is related to safety and operation standards, and it should not be underestimated.
The way to safe production, the first priority is the suitability of the environment. The preparation site should be well ventilated to avoid the accumulation of harmful gases. Temperature and humidity must also be constantly controlled. If it is too cold, too hot, too dry and too wet, it can cause reaction disorder and endanger safety.
Furthermore, the raw materials are well stored. P-Iodobenzonitrile should be placed in a cool, dry place away from fire and heat sources. Classified storage, do not mix with easily reactive objects to prevent accidents. When taking it, you must follow the quantitative regulations, and you must not be greedy for too much, which will make it difficult to dispose of the residual material.
Operating specifications are also the main point. The operator should first learn its nature and understand its risks. Wear protective equipment, such as protective clothing, gloves, goggles, etc., to protect yourself. In the operation room, the instrument must be precisely debugged, and the reaction conditions must be controlled in detail. The degree of heating and stirring is in accordance with the regulations and cannot be changed without authorization.
After the reaction is completed, the product disposal also needs to be cautious. According to the principle of environmental protection, the waste should be properly disposed of and should not be dumped at will. If there is any residue of P-Iodobenzonitrile, it should be recycled or degraded according to a specific method to avoid polluting the environment.
In general, P-Iodobenzonitrile's safe production and operation practices are related to the quality of people, the environment and results. Practitioners should keep it in mind and do it every day to ensure that everything goes smoothly and is safe.

Application Area

P-Iodobenzonitrile is a significant compound in organic synthesis. It has a wide range of application fields and can be used as a key intermediate in the field of medicinal chemistry. In the construction of many drug molecules, it is necessary to introduce specific functional groups to shape the unique chemical structure of the drug, and then endow the drug with specific physiological activities and curative effects.
In the field of materials science, P-Iodobenzonitrile can participate in the synthesis of materials with special properties. For example, when preparing polymer materials with photoelectric properties, the reactions it participates in can precisely regulate the molecular structure and properties of the material, so that the material exhibits excellent properties in photoelectric conversion and luminescence.
In addition, in the field of fine chemicals, P-Iodobenzonitrile also plays an important role. It can be used to synthesize high-value-added fine chemicals, generating considerable economic benefits for the chemical industry and assisting technological innovation and product upgrading in related fields.

Research & Development

In recent years, those who have studied chemical substances have focused on P-Iodobenzonitrile. This compound has unique characteristics and is of great value for investigation. We have tried our best to study its synthesis method. At first, we tried to prepare it with common raw materials according to traditional techniques, but the yield was not satisfactory.
Then we thought about changes, consulted ancient books and classics, absorbed the strengths of various families, and improved the process. After repeated trials, the conditions of the reaction were adjusted, and the ratio of temperature, pressure, and reagents was carefully considered. Finally obtained, the yield gradually increased and the quality was excellent.
And this compound has broad application prospects in the fields of medicine and materials. We will continue to explore and tap its potential, with the hope of contributing to the development of chemistry and the well-being of the world, and promoting its brilliance in various industries, so as to achieve our scientific research ambitions.

Toxicity Research

Nowadays, there is a chemical substance called P-Iodobenzonitrile, and the study of its toxicity is quite important. We study it from ancient methods to investigate its properties in detail.
P-Iodobenzonitrile has a unique structure, and it contains groups or induces toxicity. After various tests, observe its response to other substances, and measure its changes in different environments. It is found that this substance is in contact with a living body, or disturbs its physiological order.
The appearance of toxicity also depends on the dose. Little or no harm is found, and if it is too bad, it will be a disaster. Therefore, if you want to know its true toxicity, you must try it many times to observe its effect on various organisms.
To sum up, the study of the toxicity of P-Iodobenzonitrile still needs to be further explored, so that those who use this product can avoid harm and benefit, and ensure safety and health.

Future Prospects

In the future, when I am at P-Iodobenzonitrile, my heart will be grand. Its characteristics are unique, and its uses are vast. If it is unseen, it will lead me to explore more and more.
I want to study its method carefully, so that the higher the degree, the more the quantity. Or improve the workmanship, so as to save the source and reduce the dyeing, which is in line with the way of nature in heaven and earth.
The field of its application also hopes to expand. The way of, or to help research special effects and remedies, to relieve the pain of illness; the world of materials, or to create new things, to reduce the extraordinary nature of utensils.
I believe that in the next few days, P-Iodobenzonitrile will make great achievements in science and technology, people's livelihood and well-being, and add color to the world. This is what I hope for, and it will not be great.

Where to Buy P-Iodobenzonitrile in China?

As a trusted P-Iodobenzonitrile manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading P-Iodobenzonitrile supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of P-iodobenzonitrile?

P-iodobenzonitrile is a widely used compound in organic synthesis. Its main uses are roughly three. First, it is a key intermediary in the field of pharmaceutical chemistry. The construction of many drug molecules depends on the participation of P-iodobenzonitrile in the reaction. Due to the characteristics of iodine atoms and cyanyl groups in its structure, it can be connected with other molecular fragments by various organic reactions, such as coupling reactions, to synthesize compounds with specific pharmacological activities. For example, when developing some anti-cancer drugs, they can be introduced into the molecular structure of the drug through specific reaction steps, and then the important properties such as drug activity, solubility and targeting can be adjusted. Second, it also has extraordinary performance in the field of materials science. It can be used as a precursor for the preparation of special functional materials. After specific chemical transformation, it can become a component of optoelectronic materials. Because of the electronic properties imparted by its molecular structure, it can improve the conductivity and fluorescence properties of materials, etc., it is used in the preparation of organic Light Emitting Diodes (OLEDs), solar cells and other materials, contributing to the improvement of material properties. Third, in the synthesis of fine chemicals, its role should not be underestimated. For example, when synthesizing fine chemicals such as special dyes and fragrances, P-iodobenzonitrile can be used as a starting material or an important intermediate. Through the chemical modification of its cyanyl and iodine atoms, complex and unique molecular structures can be constructed to meet the needs of special structures and properties in the field of fine chemicals. In short, P-iodobenzonitrile plays an important role in the synthesis of drugs, materials and fine chemicals with its unique molecular structure, and promotes scientific research and industrial development in related fields.

What are the synthesis methods of P-iodobenzonitrile?

There are several ways to make p-iodobenzonitrile. The first method is to use p-iodotoluene as the starting material, and the methylation can be made into a carboxyl group by a mild oxidation process to obtain p-iodobenzoic acid. Later, the acid interacts with ammonia to form p-iodobenzamide, and then through the dehydration step, the final product is p-iodobenzonitrile. During this process, the oxidation step can be used, such as potassium permanganate, under suitable temperature and pressure, to control the reaction. When the amide is dehydrated, phosphorus pentoxide is often used as the dehydrating agent. Another method uses p-iodobromobenzene as the starting material and first interacts with magnesium to make Grignard reagent. After reacting this Grignard reagent with cuprous cyanide, a cyanyl group can be introduced to obtain p-iodobenzonitrile. In this process, when making Grignard reagent, it is necessary to be in an anhydrous and anaerobic environment to ensure a smooth reaction. When reacting with cuprous cyanide, it is also necessary to pay attention to the temperature and the proportion of reagents. Another method is to use benzonitrile as the starting material and use an iodine substitution reagent for iodization to obtain p-iodobenzonitrile. This iodine substitution reagent, such as iodine, is combined with an appropriate oxidizing agent, such as iodine and hydrogen peroxide. When reacting, pay attention to controlling the reaction conditions, such as temperature, pH, etc., All kinds of production methods have their own advantages and disadvantages, and it is necessary to choose the right one according to actual needs.

What are the physical properties of P-iodobenzonitrile?

P-iodobenzonitrile is one of the organic compounds. Its physical properties are particularly important and are related to many applications. Looking at its appearance, under normal temperature and pressure, it often takes a white to light yellow crystalline powder shape, which is easy to identify and handle. When talking about the melting point, it is about 120-124 ° C. The characteristics of the melting point are very important for identifying the substance and controlling the temperature in a specific process operation. When heated to this temperature range, the state of the substance gradually changes from solid to liquid, which has a profound impact on chemical synthesis, material preparation and other processes. Its boiling point is quite high, usually around 304.5 ° C. The boiling point characterizes the temperature conditions required for the substance to transform from liquid to gaseous state. In distillation, separation and other operations, this parameter provides the basis for precise control. The density of P-iodobenzonitrile is about 1.83 g/cm ³. Density, as an inherent property of a substance, is indispensable in measuring the relationship between its mass and volume, and is also of great significance in material ratio and reaction system design. In addition, its solubility also has characteristics. In organic solvents such as dichloromethane, chloroform, N, N-dimethylformamide (DMF), etc., it exhibits good solubility, which makes it can be used as a reactant or intermediate in organic synthesis reactions, with the help of suitable organic solvents to build a homogeneous reaction environment and promote the smooth progress of the reaction. However, in water, its solubility is very small, which is due to the difference between the molecular structure and the polarity of water. These physical properties, such as appearance, melting point, density and solubility, are interrelated and together shape the unique position of P-iodobenzonitrile in the field of chemistry, laying the foundation for its application in organic synthesis, pharmaceutical research and development, materials science and many other fields.

What are the precautions for P-iodobenzonitrile in storage and transportation?

For P-iodobenzonitrile, the raw materials for chemical reactions must be stored and transported with caution. When storing, it is advisable to choose a cool and dry place to avoid hot topics and fires. This material is easy to decompose when heated, which is dangerous. It should be well ventilated and free from gas accumulation. And it should be stored with oxidizing agents, acids, and alkalis, and should not be mixed. If it encounters them, it may cause severe reactions and cause danger. The packaging must also be tight to prevent leakage. When shipping, the driver and the prisoner must understand the nature of this thing and the emergency method. Transport equipment must be clean and free of other residues, especially not mixed with contraband. Protect from exposure to the sun, rain and high temperature on the way. If it is transported by road, follow the regulations and avoid crowded places and busy cities. When transporting by railway, follow the regulations on the transportation of dangerous goods by railway. When loading and unloading, handle it with care, do not drop it, heavy pressure, and avoid packaging damage and material leakage. In short, the storage and transportation of P-iodobenzonitrile is related to safety and security, and all sections must be carried out in accordance with regulations, and there must be no sparse, so as to keep it safe.

What is the market price range for P-iodobenzonitrile?

I think what you are asking is about the market price range of p-iodobenzonitrile. Sadly, the price of this chemical often changes for a variety of reasons, and it is difficult to determine its fixed price. First, the price of raw materials fluctuates. The preparation of p-iodobenzonitrile requires specific raw materials. If the price of raw materials rises or falls, the price of finished products will fluctuate. Second, the trend of supply and demand is also critical. If the market increases its demand and the supply is limited, the price will rise; conversely, if the supply is abundant and the demand is weak, the price may fall. Third, the difficulty of production, the quality of the process, and the cost of packaging and transportation all affect its price. Generally speaking, the price of p-iodobenzonitrile in the chemical market varies according to purity, packaging, purchase quantity, etc. The price is usually higher for those with high purity; large packages, large purchases, or preferential prices. And different regions, due to differences in economic level and logistics costs, prices also vary. It is difficult to accurately tell you its price range today, but if you want to know more, you can consult chemical raw material suppliers, distributors, or check the latest quotations of chemical product trading platforms, so that you can get more accurate market price information.