Pyridine 2 3 Dichloro 4 Iodo
Iodobenzene

Pyridine, 2,3-dichloro-4-iodo-

Fengxi Chemical

Specifications

HS Code

980554

Chemical Formula C5H2Cl2IN
Molecular Weight 286.88
Appearance Solid (predicted)
Boiling Point N/A
Melting Point N/A
Density N/A
Solubility In Water Insoluble (predicted)
Solubility In Organic Solvents Soluble in common organic solvents (predicted)
Flash Point N/A
Vapor Pressure N/A
Pka N/A
Chemical Formula C5H2Cl2IN
Molecular Weight 286.887
Chemical Formula C5H2Cl2IN
Molecular Weight 290.887 g/mol
Appearance Solid (predicted)
Solubility In Water Poorly soluble (predicted)
Logp 3.41 (predicted)
Chemical Formula C5H2Cl2IN
Molecular Weight 290.887
Appearance Solid (predicted)
Boiling Point 304.6±42.0 °C at 760 mmHg (predicted)
Melting Point 89 - 91 °C
Density 2.231±0.06 g/cm3 at 20 °C (predicted)
Vapor Pressure 0.0±0.7 mmHg at 25 °C (predicted)
Logp 3.56 (predicted)
Solubility Soluble in organic solvents like dichloromethane, chloroform (general behavior for such compounds)
Flash Point 138.0±27.9 °C (predicted)
Packing & Storage
Packing 100g of 2,3 - dichloro - 4 - iodopyridine in a sealed, labeled chemical container.
Storage Store "2,3 - dichloro - 4 - iodopyridine" in a cool, dry, well - ventilated area, away from heat sources and ignition sources. Keep it in a tightly - sealed container, preferably made of corrosion - resistant materials. As it is a chemical, store it separately from incompatible substances like oxidizing agents, reducing agents, and strong acids or bases to prevent reactions.
Shipping Pyridine, 2,3 - dichloro - 4 - iodo - is shipped in accordance with strict chemical transportation regulations. It is carefully packaged in corrosion - resistant containers to prevent leakage during transit, ensuring safe delivery.
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Pyridine, 2,3-dichloro-4-iodo- Pyridine, 2,3-dichloro-4-iodo- Pyridine, 2,3-dichloro-4-iodo-
General Information
Frequently Asked Questions
What are the physical properties of 2,3-dichloro-4-iodopyridine?
2% 2C3-dideuterium-4-cyanopyridine is an organic compound. Its physical properties are quite unique, and are described as follows:
Looking at its appearance, under room temperature and pressure, it is mostly white to light yellow crystalline powder, which is convenient for observation and preliminary identification.
When it comes to the melting point, it is about 100-105 ° C. The melting point is a key physical property of a substance. This temperature range indicates that the solid and liquid states of the compound reach equilibrium at this specific temperature, the lattice structure begins to disintegrate, and the intermolecular forces change, transforming from solid to liquid.
In terms of boiling point, it is about 300-310 ° C. The boiling point reflects the temperature at which a compound changes from liquid to gaseous under a specific pressure. At this temperature, the compound molecules obtain enough energy to overcome the attractive forces between molecules and escape from the liquid surface to form a gas.
As for solubility, it is slightly soluble in water. Water is a common solvent, and this solubility indicates that the force between the compound and water molecules is relatively weak, and only a small amount of molecules can be dispersed in water. However, it is easily soluble in common organic solvents, such as dichloromethane, ethanol, acetone, etc. This indicates that there are more matching interactions between the compound and these organic solvent molecules, such as van der Waals forces, hydrogen bonds, etc., making it easier to disperse uniformly in organic solvents. The density of
is about 1.2 to 1.3 g/cm ³. This value reflects the mass of the compound per unit volume, revealing its relative relationship with the mass of other substances under the same volume. It is of great significance in practical application scenarios such as the measurement, storage and transportation of substances.
Many of the above physical properties have reference value for the application of this compound in chemical synthesis, materials science, drug development and many other fields.
What are the chemical properties of 2,3-dichloro-4-iodopyridine?
2% 2C3-difluoro-4-cyanopyridine is an organic compound with many unique chemical properties and is widely used in organic synthesis and other fields.
It is basic, and the nitrogen atom of the pyridine ring does not share a common electron pair, which can react with acids to form salts. In the case of strong acids, nitrogen atoms are easy to accept protons and exhibit basic characteristics. This property is often used for the separation and purification of the compound, or as a catalyst in specific reactions.
2% 2C3-difluoro-4-cyanopyridine has high cyano activity. Cyanyl groups can undergo a variety of reactions, such as hydrolysis reactions. Under the catalysis of acids or bases, cyanyl groups can be gradually converted into carboxylic groups to generate corresponding carboxylic acid compounds; they can also participate in nucleophilic addition reactions. Cyanyl carbon atoms are positively charged and vulnerable to nucleophilic reagents. They undergo addition reactions with compounds containing active hydrogen, such as alcohols and amines, to form new carbon-hetero bonds and expand the molecular structure.
Furthermore, the fluorine atoms in this compound give it special properties. The fluorine atoms are highly electronegative, which makes the carbon-fluorine bond polarity strong. This not only affects the physical properties of the molecule, such as boiling point and solubility, but also has a significant effect on its chemical properties. Due to the relatively stable carbon-fluorine bond, molecular stability can be enhanced; at the same time, the electron-withdrawing effect of fluorine atoms will affect the electron cloud density distribution on the pyridine ring, change the reactivity at other positions on the ring, and promote electrophilic substitution reactions that are easier or more difficult to occur at specific locations.
In addition, 2% 2C3-difluoro-4-cyanopyridine can be used as an important intermediate for the synthesis of complex organic molecules. With the reactivity of cyano, fluorine atoms and pyridine rings, through ingenious design of reaction routes, it can react with a variety of reagents to construct organic compounds with different structures and functions, which play a key role in pharmaceutical chemistry, materials science and other fields.
What are the main uses of 2,3-dichloro-4-iodopyridine?
2% 2C3-dideuterium-4-chloropyridine, although this substance is not directly recorded in Tiangong Kaiwu, it has a wide range of uses based on current chemical science.
In the field of pharmaceutical synthesis, it can be a key intermediate. The special structure of the Geynepyridine ring endows the compound with unique chemical and physiological activities. Through specific chemical reactions, 2% 2C3-dideuterium-4-chloropyridine can be introduced into the molecular structure of the drug, thereby adjusting the pharmacological properties of the drug, such as enhancing the affinity of the drug to specific targets, enhancing its efficacy, or optimizing the metabolic properties of the drug, reducing toxic and side effects.
It is also of great value in the creation of pesticides. Pyridine compounds often exhibit excellent insecticidal, bactericidal and herbicidal activities. 2% 2C3-dideuterium-4-chloropyridine can be used as a basic unit for the construction of new pesticide molecules. Through rational molecular design and modification, high-efficiency, low-toxicity and environmentally friendly pesticide varieties can be developed, which can help agricultural pest control and ensure crop harvest.
In addition, in the field of materials science, it may also be useful. For example, it can participate in the synthesis of functional organic materials, endowing materials with specific electrical, optical or mechanical properties, providing new avenues and possibilities for the research and development of new materials. Although "Tiangong Kaiwu" did not cover this object, today, the evolution of chemical technology has made it play an indispensable role in many key fields, promoting the sustainable development of industries such as medicine, agriculture, and materials.
What are the synthesis methods of 2,3-dichloro-4-iodopyridine?
2% 2C3-dihydro-4-quinolinone is an important class of organic compounds. Its synthesis methods are various, and it is described in ancient Chinese.
First, it can be formed by condensation and cyclization of aniline and ethyl acetoacetate. First take an appropriate amount of aniline, place it in a clean kettle, add ethyl acetoacetate, and then add an appropriate amount of catalyst, such as anhydrous sodium acetate. Heat it slowly at a suitable temperature to make it fully react. This process requires careful temperature control, so as not to make the temperature too high or too low, so as not to affect the reaction process. In the meantime, the reactant slowly undergoes a condensation reaction to form an intermediate product. Then, under specific conditions, the intermediate product is further cyclized to give 2% 2C3-dihydro-4-quinolinone.
Second, it can also be obtained by using o-aminoacetophenone and ethyl formate as raw materials. The o-aminoacetophenone is placed in the reaction vessel, injected into ethyl formate, and an appropriate amount of alkali is added, such as sodium ethanol. The role of the base is to catalyze the reaction. At the beginning of the reaction, it is necessary to keep a low temperature, wait for the reaction to be smooth, and gradually heat up to a suitable temperature. The o-aminoacetophenone and ethyl formate first undergo a condensation reaction to form a key intermediate, and then the intermediate is cyclized and rearranged to obtain the target product.
Third, it is prepared by the reaction of aniline and acrylate. Take aniline and acrylate, mix them in a reaction kettle in a certain proportion, and add a specific catalyst, such as Lewis acid. The reaction starts under mild conditions and gradually heats up. The Michael addition reaction of aniline and acrylate first generates the addition product. In the subsequent reaction, the product is cyclized within the molecule and converted into 2% 2C3-dihydro-4-quinolinone.
The above methods have their own advantages and disadvantages. They need to be used according to the actual situation, such as the availability of raw materials, the difficulty of reaction conditions, and the purity of the product.
What are the precautions for storing and transporting 2,3-dichloro-4-iodopyridine?
2% 2C3-dideuterium-4-chloropyridine requires attention to many key matters during storage and transportation. This compound has special properties, and when storing, the first environment should be selected. It should be placed in a cool, dry and well-ventilated place to prevent moisture and heat. Humidity will not cause reactions such as hydrolysis. If the temperature is too high, it may cause decomposition, endangering safety and compromising its quality.
Storage containers are also crucial. Be sure to choose suitable materials, such as corrosion-resistant glass bottles or specific plastic containers, to avoid contact with active metals, because they may react with metals. Containers should be tightly sealed to avoid contact with air to prevent oxidation or reaction with airborne components.
When transporting, the packaging must be stable and reliable. Follow relevant regulations and use appropriate packaging materials and labels to ensure that transporters are aware of its dangerous characteristics and emergency treatment methods. During transportation, stable conditions should be maintained to avoid violent vibrations, collisions and large temperature fluctuations.
In addition, regardless of storage or transportation, safety operation practices must be strictly implemented. Operators should be professionally trained and familiar with the characteristics and risks of the compound. At the same time, corresponding protective and emergency treatment equipment, such as protective gloves, glasses, first aid medicines, etc., should be equipped in order to respond to emergencies in a timely manner. In short, the storage and transportation of 2% 2C3-dideuterium-4-chloropyridine must be done with great care to ensure safety and quality in all aspects.