Pyridine, 2,5-difluoro-4-iodo-

This "Pyridine, 2,5-difluoro-4-iodo-" is the name of the organic compound. According to chemical nomenclature, "Pyridine" is the English name for pyridine. Pyridine is a nitrogen-containing six-membered heterocyclic compound with aromatic rings.
"2,5-difluoro-4-iodo-" is the description of the substituent on the pyridine ring. "2,5-difluoro" means that there is a fluorine atom (F) connected to each of the 2nd and 5th positions of the pyridine ring. Fluorine, a halogen element, is highly electronegative. " 4-Iodo - "means that there is an iodine atom (I) attached to the 4th position of the pyridine ring, and iodine is also a halogen element.
Therefore, the chemical structure of the compound is based on the pyridine ring as the parent nucleus, with a fluorine atom substituted at the 2nd and 5th positions, and an iodine atom substituted at the 4th position. Its structure can be shown as follows: Based on the pyridine ring, first draw the six-membered ring of the pyridine, in which a nitrogen atom occupies one place in the ring, and then connect the fluorine atom at the 2nd and 5th positions of the ring, respectively, and connect the iodine atom at the 4th position. In this way, the chemical structure of" Pyridine, 2,5-difluoro-4-iodo - "can be obtained.

"Pyridine, 2,5-difluoro-4-iodine -" This substance has important uses in many fields. In the field of medicinal chemistry, it is often used as a key intermediate, paving the way for the synthesis of specific drugs. Due to its unique chemical structure, it can precisely combine with specific targets in organisms, helping to develop new drugs for difficult diseases, such as anti-cancer and anti-viral agents, just like finding the key to solving the dilemma of diseases.
In the field of materials science, it also has extraordinary value. It can participate in the preparation of functional materials with excellent performance, such as optoelectronic materials. With its own characteristics, the material is endowed with unique optical and electrical properties, which are used to create high-efficiency Light Emitting Diodes, solar cells, etc., just like injecting magical energy into the material, making it shine in the world of light and electricity.
In the field of organic synthetic chemistry, it is like a skilled craftsman, a powerful tool for building complex organic molecular structures. Chemists use its unique reactivity to ingeniously build various organic compound frameworks, greatly expanding the boundaries of organic synthesis, providing unlimited possibilities for the creation of novel organic molecules, just like throwing creative brushes in the palace of chemistry.
In the research and development of pesticides, it has also made a name for itself. As a raw material, it can synthesize high-efficiency and low-toxicity pesticides, accurately attack crop pests, and reduce the harm to the environment and non-target organisms. It contributes to protecting the harvest of farmland and safeguarding the ecological environment, just like a loyal guardian of farmland.
In short, "Pyridine, 2,5-difluoro-4-iodine -" plays an indispensable role in many important fields due to its unique chemical properties, promoting scientific and technological progress and industrial development.

"Pyridine, 2,5-difluoro-4-iodine -" This substance is an organic compound with unique physical properties. Looking at its morphology, at room temperature, it may be a colorless to pale yellow liquid or a crystalline solid, depending on the intermolecular force and the degree of structural compactness.
Regarding odor, due to its nitrogen-containing heterocyclic structure, or emitting a specific pungent odor, this odor may be related to the inherent characteristic odor of pyridine, but also slightly changed due to the introduction of fluorine and iodine atoms.
In terms of boiling point, due to the presence of fluorine and iodine atoms, the intermolecular force is enhanced, resulting in a higher boiling point than that of pyridine. Although the fluorine atom is small, it has high electronegativity, which can enhance the dipole-dipole interaction between molecules; the large volume and high polarizability of the iodine atom also increase the intermolecular dispersion force. The synergistic effect of the two increases the boiling point of the compound, but the exact value needs to be determined experimentally and accurately.
Melting point is also affected by structure and atomic properties. The substitution of fluorine and iodine atoms at specific positions in the pyridine ring, or the change of molecular stacking mode, which in turn affects the lattice energy. The strong electronegativity of fluorine atoms may cause molecules to be polarized, and the large volume of iodine atoms or the close stacking of interfering molecules will also change the melting point.
In terms of solubility, the compound may have some solubility in organic solvents. Due to the lipophilic structure of the pyridine ring, it can interact with the non-polar part of the organic solvent; although the fluorine and iodine atoms have a certain polarity, the whole molecule still has a certain lipid solubility, and it may have a good solubility in common organic solvents such as dichloromethane, chloroform, ether, etc. However, in water, due to its relatively strong overall non-polarity and lack of groups that form strong hydrogen bonds with water, the solubility is poor.
The size of the density, due to the relatively large atomic weight of fluorine and iodine atoms, compared with pyridine, its density may increase. Although fluorine atoms are light in weight, iodine atoms are large in weight and have a large atomic radius, which has a significant impact on the space occupied by molecules, resulting in an increase in mass and density per unit volume.
The physical properties of this compound are determined by its unique molecular structure and atomic properties, and the properties are interrelated, which has far-reaching impact on its applications in chemical synthesis, materials science and other fields.

To prepare "2,5-difluoro-4-iodopyridine", there are many synthesis methods, each with its own advantages and disadvantages, and needs to be selected according to the actual situation. The following are common numbers:
First, pyridine is used as the initial raw material. The first step of fluorination of pyridine can be achieved by means of a nucleophilic substitution reaction. Appropriate fluorination reagents, such as potassium fluoride, are selected. Under specific reaction conditions, such as high temperature and specific solvents, fluorine atoms are introduced at specific positions on the pyridine ring to obtain fluorine-containing pyridine intermediates. Subsequently, the iodization reaction is carried out on the intermediate, usually using iodine elemental as iodizing agent. In the presence of catalysts such as copper salts, iodine atoms replace hydrogen atoms at specific positions on the pyridine ring to obtain the target product "2,5-difluoro-4-iodopyridine". This path step is relatively clear, but the reaction conditions of each step need to be precisely controlled to improve the yield and selectivity.
Second, starting from other simple compounds containing fluorine and iodine, it is synthesized by the strategy of constructing pyridine rings. For example, using fluorine-containing dicarbonyl compounds and iodine-containing amine compounds as raw materials, pyridine rings are constructed by multi-step reactions. First, the fluorine-containing dicarbonyl compound and the iodine-containing amine compound undergo condensation reaction under the action of condensation reagents to initially form the prototype of the pyridine ring, and then through a series of functional group transformation and modification reactions, the substituents on the pyridine ring are adjusted, and finally "2,5-difluoro-4-iodine pyridine" is synthesized. Although the starting materials may be relatively easy to obtain, the reaction process is complicated and requires high reaction skills.
Third, transition metal-catalyzed cross-coupling reactions can also be used. First prepare fluoropyridine derivatives with suitable leaving groups (such as halogen atoms, borate esters, etc.), and prepare nucleophiles containing iodine. In the presence of transition metal catalysts (such as palladium catalysts) and ligands, the two are cross-coupled to introduce iodine atoms to specific positions of fluoropyridine to achieve the synthesis of "2,5-difluoro-4-iodopyridine". This method has good selectivity and yield is usually considerable, but the cost of catalysts and ligands is high, and the reaction conditions are relatively harsh, which requires not low reaction equipment and operation.
In short, the methods for synthesizing "2,5-difluoro-4-iodopyridine" have their own advantages. In actual synthesis, many factors such as raw material availability, cost, reaction conditions, and purity of target products should be considered comprehensively, and the appropriate synthesis path should be carefully selected.

I don't know what the price range of "pyridine, 2,5-difluoro-4-iodine -" is in the market. The price of this compound often varies due to various factors, such as its purity, difficulty in preparation, and market supply and demand.
If its preparation requires complicated steps, special raw materials or conditions, the cost will be high and the price will rise. High purity is more expensive than general purity, because purification requires more resources and processes.
The impact of market supply and demand is particularly severe. If there are many people who want it and the supply is small, the price will rise; on the contrary, if the supply exceeds the demand, the price may decline.
However, we do not have real-time price information at hand. If you want to know more about it, you can consult the chemical reagent supplier, or refer to the chemical product trading platform. There may be similar product quotations on it, which can be used for reference to help you determine its price range.