As a leading (S)-2-Amino-3-[4-(4-Hydroxy-3-Iodophenoxy)-3,5-Diiodophenyl]Propionic Acid Sodium Salt supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of (s) -2-amino-3- [4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl] propionic Acid Sodium Salt
This is the sodium salt of (S) -2-amino-3- [4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl] propionic acid. Its chemical structure is as follows:
The core of this compound is propionic acid, and the α-carbon atom of propionic acid is chiral and has an S configuration. There are amino groups attached to the 2 positions of propionic acid, which are basic and can participate in salt-forming reactions. It can also be used as nucleophiles in organic synthesis and biochemical reactions.
is connected to a complex aryl substituent at the 3 position of propionic acid. This substituent is composed of a phenyl ring connected to another phenoxy phenyl ring. At the 4 position of the phenoxy phenyl ring, there is a hydroxyl group. The hydroxyl group can not only form hydrogen bonds, which affect the intermolecular forces and solubility, but also serve as a check point for reactivity, participating in esterification, etherification and other reactions. The 3rd and 5th positions are both iodine atomic substitutions. The atomic radius of the iodine atom is large and the electronegativity is moderate, which will affect the electron cloud distribution, steric resistance and chemical activity of the molecule. The 4th position of the phenyl ring is connected to another phenyl ring through oxygen atoms. This ether bond is relatively stable, but it may also break under certain conditions, such as in a strongly acidic or strongly basic environment and with appropriate reagents.
In the whole molecule, due to the presence of carboxyl sodium salt form, it has good solubility in water. Due to the formation of ionic bonds between carboxyl negative ions and sodium ions, the ionic bonds are easily dissociated under the action of polar water molecules, thereby improving the solubility of the compound in water. This structural characteristic makes the compound may show unique properties and uses in medicine, biochemistry and other fields, or it can be designed and synthesized with specific physiological activities by virtue of its structure and activity check point.
What are the main uses of (s) -2-amino-3- [4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl] propionic Acid Sodium Salt
(S) -2 -amino-3- [4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl] propionate sodium salt, which is an important compound. It has a wide range of uses and is often used as a thyroid hormone analogue in the field of medicine. Because the structure of this compound is similar to thyroid hormones and can mimic the physiological effects of thyroid hormones, it may have the effect of regulating thyroid function in the treatment of thyroid diseases.
In the field of scientific research, this compound is also an important research tool. By studying it, scientists can deeply explore the mechanism of action of thyroid hormones, signal transduction pathways and other basic biological issues, and help expand the understanding of the human endocrine system.
In the process of drug development, (S) -2 -amino-3- [4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl] propionate sodium salt can act as a lead compound. After structural modification and optimization, it is expected to develop new thyroid diseases with better efficacy and less side effects, bringing good news to many patients.
What are the physical properties of (s) -2-amino-3- [4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl] propionic Acid Sodium Salt
(S) -2-amino-3- [4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl] propionate sodium salt, which is an organic compound with specific physical properties.
Its properties are often white to off-white powder or crystalline. Under normal temperature and pressure, the substance is quite stable, and if proper storage conditions are followed, its chemical structure and properties can be maintained for a long time.
In terms of solubility, due to the structure of sodium salts, it exhibits good solubility in water and can form a uniform solution. This property provides convenience for its application in many aqueous systems. For example, in the field of pharmaceutical preparations, if it is made into an aqueous solution dosage form, it is easier for the human body to absorb.
Melting point is also an important physical property, but the specific value will fluctuate due to factors such as crystal morphology and purity. Usually, the melting point range can be accurately obtained by professional measurement methods, which is of great significance for identification and quality control. For example, in pharmaceutical production, melting point measurement can be used as one of the key indicators to judge product purity.
In addition, its density is also a specific constant. Although the specific data needs to be accurately measured by professional instruments, density information is indispensable for understanding its distribution in different media and related process design. For example, in chemical production processes, operations such as material transportation and mixing can be planned according to density.
What is the synthesis method of (s) -2-amino-3- [4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl] propionic Acid Sodium Salt
The synthesis of (S) -2-amino-3- [4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl] propionate sodium salt is a subject of great concern in chemical synthesis. The synthesis process requires multiple steps of delicate reactions.
At the beginning, suitable aromatic compounds can be selected as raw materials, such as benzene derivatives with specific substituents. The benzene ring is first halogenated to introduce iodine atoms. This step requires precise control of the reaction conditions, such as reaction temperature and the amount of halogenated reagents, to ensure that iodine atoms are substituted at specific positions in the benzene ring to achieve the preparation of 3,5-diiodobenzene derivatives.
Then, the hydroxyl-containing benzene ring derivatives are condensed with the above halogenated products to form ether bonds and construct a 4- (4-hydroxy-3-iodophenoxy) -3,5-diiodobenzene structure. This condensation reaction also needs to be carefully controlled, and suitable catalysts and solvents are selected to improve the yield and selectivity of the reaction.
Then, the alanine structure fragment is introduced by suitable methods. Or, alanine derivatives containing carboxyl and amino protecting groups can be prepared first, and then reacted with the above-mentioned constructed benzene derivatives, and then through the deprotection step, (S) -2 -amino-3- [4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl] propionic acid can be obtained.
Finally, the propionic acid is reacted with basic substances such as sodium hydroxide to form a sodium salt. This process requires attention to the pH value of the reaction to ensure the purity and quality of the sodium salt. The whole synthesis path, each step of the reaction requires meticulous operation and strict control of conditions, in order to obtain the target product (S) - 2 -amino - 3 - [4 - (4 - hydroxy - 3 - iodophenoxy) - 3,5 - diiodophenyl] propionate sodium salt efficiently and with high purity.
What is the market price of (s) -2-amino-3- [4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl] propionic Acid Sodium Salt
(S) -2 -Amino-3- [4- (4 -hydroxy-3 -iodophenoxy) -3,5 -diiodophenyl] propionate sodium salt, this is a rather professional chemical substance. In terms of market price, it is difficult to have a fixed number, because multiple factors are intertwined, which affects its price trend.
The first to bear the brunt is the cost of raw materials. This compound requires a lot of raw materials for synthesis, and its price fluctuates frequently. If raw materials are scarce, or extraction and preparation are difficult, the cost will rise, which will then push up the price of the substance. If the required iodide, if the supply is tight and the price soars, the price of this compound will also be affected by it.
Furthermore, the complexity of the synthesis process has a deep impact on the price. If the synthesis steps are complicated, multiple reaction steps are required, and each step requires strict conditions, such as precise temperature and pressure control, and the use of high-purity catalysts, it will not only consume time and effort, but also increase production costs, and the price will be expensive.
In addition, the relationship between market supply and demand is also key. If the compound is in high demand in the fields of medicine, scientific research, etc., and the production supply is relatively limited, according to economic common sense, the price will rise. On the contrary, if demand is low and overproduction, the price may fall.
In addition, the scale of production should not be underestimated. In large-scale production, due to the scale effect, the unit production cost may be reduced, and the price may be slightly more accessible to the people; however, in small-scale production, the cost sharing is higher, and the price is often higher.
To sum up, in order to know the exact market price, it is necessary to carefully investigate the raw material market dynamics, synthesis process details, market supply and demand, and production scale. After comprehensive research and judgment, relatively accurate price information can be obtained.