As a leading (S)-7-Fluoro-1-(1-Hydroxymethyl-2-Methyl-Propyl)-6-Iodo-4-Oxo-1,4-Dihydro-Quinoline-3-Carboxylic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of (s) -7-fluoro-1- (1-hydroxymethyl-2-methyl-propyl) -6-iodo-4-oxo-1, 4-dihydro-quinoline-3-carboxylic Acid?
(This compound) (S) -7-fluoro-1- (1-hydroxymethyl-2-methyl-propyl) -6-iodine-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid, looking at its name, it can be known that this is an organic compound containing a quinoline parent nucleus. The following is a detailed analysis of its structure in ancient Chinese.
quinoline, which is a nitrogen-containing heterocyclic aromatic hydrocarbon, has the shape of a benzene ring fused with a pyridine ring. This compound has a hydrogen atom substitution at the 1,4-dihydro position of the quinoline parent nucleus, and the 4 position is an oxygen substitution group, that is, it has a carbonyl structure. The existence of this carbonyl group affects the electron cloud distribution and reactivity of the molecule. The fluorine atom is introduced at the
7 position, and fluorine has strong electronegativity, which can change the polarity and physicochemical properties of the molecule. There is an iodine atom at the 6 position, and the iodine atom is relatively large, which also has a significant effect on the molecular space structure and reaction characteristics.
1-linked (1-hydroxymethyl-2-methyl-propyl) group, this group contains hydroxymethyl and two methyl groups. The hydroxyl group in the hydroxymethyl group can participate in the formation of hydrogen bonds, which affects the solubility and biological activity of the compound; methyl is the power supply group, which has an impact on the electron cloud density of the molecule, and the existence of this side chain makes the molecular space structure more complex and affects its interaction with other molecules.
The 3-position is the carboxylic acid group, and -COOH is acidic, which can participate in acid-base reactions, esterification reactions, etc., which greatly affects the chemical properties and biological activities of the compounds. The interplay of various parts of the overall structure of this compound determines its unique physical, chemical and biological properties, and may be of great value in the fields of organic synthesis and drug development.
(S) -7-fluoro-1- (1-hydroxymethyl-2-methyl-propyl) -6-iodo-4-oxo-1, what are the physical properties of 4-dihydro-quinoline-3-carboxylic Acid
(This substance) (S) -7-fluoro-1- (1-hydroxymethyl-2-methyl-propyl) -6-iodine-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid, an organic compound. Its physical properties are unique, let me tell you one by one.
Looking at its morphology, it is mostly a crystalline solid at room temperature and pressure. Due to the intermolecular forces and orderly arrangement, it has a relatively stable solid structure.
When it comes to color, it is often white or off-white, and pure is almost colorless. This is due to the absorption characteristics of visible light by the molecule, which absorbs very little in the visible spectral region, so it appears this color.
When it comes to solubility, the solubility of this substance in water is quite limited. Water is a polar solvent, and although the molecular structure of this compound contains polar groups such as carboxyl and hydroxyl groups, its main structure is relatively large and has a certain hydrophobicity, making it insoluble in water. However, in some organic solvents, such as ethanol and dichloromethane, it has good solubility. Ethanol has moderate polarity and can interact with compound molecules such as hydrogen bonds; although dichloromethane has weak polarity, it can interact with the compound by means of intermolecular van der Waals forces to achieve dissolution.
Then again, the melting point has been experimentally determined to be in a specific temperature range, which reflects the strength of intermolecular forces. A higher melting point indicates that the intermolecular forces are strong, and more energy is required to destroy its lattice structure. This is because there are various interactions in the molecule, such as hydrogen bonds 、π - π stacking, which jointly maintain the stability of the lattice.
Its density is also an important physical property, because the specific value will be affected by many factors, such as crystal morphology and purity. In general, its density is higher than that of water, which is closely related to the molecular structure. The atoms in the molecule are closely bound, and the atomic weight is relatively large, resulting in an increase in the mass per unit volume.
In summary, the physical properties of (S) -7-fluoro-1- (1-hydroxymethyl-2-methyl-propyl) -6-iodine-4-oxo-1,4-dihydro-quinoline-3-carboxylic acids are determined by their molecular structure and are of great significance in organic chemistry and related fields.
What is the main use of (s) -7-fluoro-1- (1-hydroxymethyl-2-methyl-propyl) -6-iodo-4-oxo-1, 4-dihydro-quinoline-3-carboxylic Acid?
(S) -7-fluoro-1- (1-hydroxymethyl-2-methyl-propyl) -6-iodine-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid This compound is a crucial compound in the field of organic synthesis and medicinal chemistry.
Its primary use is in pharmaceutical research and development. This compound has a unique structure and contains specific chemical groups, which show significant inhibitory activity against many pathogens. It may achieve antibacterial effect by hindering the key metabolic process of pathogens and interfering with their nucleic acid synthesis. After research, it has been found that it has the ability to inhibit some Gram-positive and negative bacteria, providing an important opportunity for the creation of new antimicrobial drugs. In the current situation of severe antibiotic resistance, the development of such new antimicrobial compounds is of great significance to solve the problem of drug-resistant bacterial infection.
Furthermore, in the field of organic synthesis, it also plays an important role. The structure of this compound can be used as a key intermediate for the construction of more complex organic molecules. With its diverse reaction check points, chemists can use various organic reactions, such as nucleophilic substitution, oxidation and reduction, to modify its structure and derivatization. Through this method, a series of compounds with different physiological activities or physical properties can be synthesized, providing a rich material basis for research in materials science, medicinal chemistry and other fields. For example, through structural modification, materials with special optical and electrical properties can be developed for the preparation of optoelectronic devices and other fields.
What are the synthesis methods of (s) -7-fluoro-1- (1-hydroxymethyl-2-methyl-propyl) -6-iodo-4-oxo-1, 4-dihydro-quinoline-3-carboxylic Acid
The synthesis of (s) -7-fluoro-1- (1-hydroxymethyl-2-methylpropyl) -6-iodine-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is an important topic in the field of organic synthesis. The synthesis of this compound can follow a variety of paths.
First, a suitable quinoline derivative is used as the starting material. After halogenation, iodine atoms are introduced at specific positions. This process requires careful selection of halogenated reagents and reaction conditions to ensure the selectivity and yield of the reaction. After alkylation, 1- (1-hydroxymethyl-2-methylpropyl) groups are introduced into the molecule. The activity of the alkylating reagent, the reaction solvent and the type of base all have a great influence on the reaction. Subsequent oxidation or other functional group conversion steps are used to construct the 4-oxo structure. The choice of oxidation reagent is related to the purity of the product and the reaction efficiency.
Second, the strategy of gradually constructing the quinoline ring can also be adopted. First prepare a phenyl ring derivative containing fluorine, iodine and appropriate substituents, and then react with an enamide containing 1- (1-hydroxymethyl-2-methylpropyl) structure or other suitable reagents to form a quinoline ring. The optimization of this cyclization reaction conditions, such as temperature, catalyst type, etc., is the key to successful synthesis. After the quinoline ring is formed, the carboxyl group is further modified to obtain the target compound.
During the synthesis process, a variety of separation and purification methods, such as column chromatography, recrystallization, etc., are required to ensure the purity of the product. And the monitoring of each step of the reaction is crucial. With the help of thin-layer chromatography, nuclear magnetic resonance and other technologies, the reaction process can be grasped in real time, and the reaction conditions can be adjusted in time, so as to improve the synthesis efficiency and product quality, and achieve the purpose of efficient synthesis of (s) -7-fluoro-1- (1-hydroxymethyl-2-methylpropyl) -6-iodine-4-oxo-1,4-dihydroquinoline-3-carboxylic acid.
What is the market outlook for (s) -7-fluoro-1- (1-hydroxymethyl-2-methyl-propyl) -6-iodo-4-oxo-1, 4-dihydro-quinoline-3-carboxylic Acid?
Nowadays, there are (s) -7-fluoro-1- (1-hydroxymethyl-2-methyl-propyl) -6-iodine-4-oxo-1,4-dihydro-quinoline-3-carboxylic acids. The market prospect of this substance is related to many aspects, and I will tell you one by one.
From the perspective of the medical field, quinoline carboxylic acids have many antibacterial activities. This compound has a unique structure and contains special atoms such as fluorine and iodine, which may enhance its ability to bind to targets. It may have extraordinary performance in antibacterial spectrum and antibacterial activity. If it can be effectively developed, or add new power to antimicrobial drugs, the market potential is considerable. The current antimicrobial drug market continues to grow, the problem of drug-resistant bacteria is becoming more and more serious, and the demand for new antimicrobial drugs is very strong. If this compound is successfully developed, it is expected to get a share of it.
In the chemical industry, it may be used as an intermediate in organic synthesis. The unique structure can be derived from a variety of compounds, providing a raw material basis for the development of fine chemical products. With the growth of demand for specialty chemicals in the chemical industry, if large-scale production can be achieved to meet the needs of chemical synthesis raw materials, it can also occupy a place in the chemical market.
However, its market prospects also pose challenges. The research and development process may encounter difficulties, such as compound stability, synthesis process complexity Poor stability may affect product quality and application, and complex synthesis processes increase production costs and weaken market competitiveness. And new drug research and development requires strict approval, which takes a long time, requires large investment, and is quite risky. If it cannot pass the approval, the early investment may be wasted.
In summary, (s) -7-fluoro-1- (1-hydroxymethyl-2-methyl-propyl) -6-iodine-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid market prospects Opportunities and challenges coexist. If we can overcome the R & D and production problems, we will be able to shine in the pharmaceutical and chemical markets.