What is the chemical structure of (s) -tert-butyl (1-amino-3- (4-iodophenyl) -1-oxopropan-2-yl) carbamate?
This is the name of (S) -tert-butyl (1-amino-3- (4-iodophenyl) -1-oxopropyl-2-yl) carbamate. To clarify its chemical structure, its name can be analyzed.
" (S) " indicates that the compound has chirality and is of the S configuration. "Tert-butyl" is a specific alkyl group with a specific carbon chain structure. "Carbamate", this is a class of structures with a specific functional group, and its general formula contains R O (C = O) N (R < 3) R < 3).
View " (1-amino-3- (4-iodophenyl) -1-oxo-propane-2-yl) " part, it can be seen that in the propyl structure, the 1-position aerobic substitution group (ie carbonyl-C = O) is connected with an amino group at the same time; the 3-position connection (4-iodophenyl), the 4-position of this phenyl group is substituted by an iodine atom.
In summary, the structure of this compound is formed by tert-butyl and the propyl group containing amino group, carbonyl group and 4-iodophenyl group, which is connected by the functional group of carbamate. The central chiral carbon is of S configuration, and each group is connected to the chiral carbon in a specific order to form the unique chemical structure of this organic compound.
What are the main uses of (s) -tert-butyl (1-amino-3- (4-iodophenyl) -1-oxopropan-2-yl) carbamate?
(S) -tert-butyl (1-amino-3- (4-iodophenyl) -1-oxypropyl-2-yl) carbamate, which has a wide range of uses and has its own impact in the field of medicine and chemical industry.
In the process of pharmaceutical research and development, it is often a key intermediate. Due to the specific structure in the molecule, it can be synthesized organically and reacted with other compounds to construct complex molecules with biological activity. For example, it may participate in the construction of drug molecules targeting specific disease targets, such as anti-tumor and antiviral drugs. Through chemical modification and transformation, it is expected to impart precise pharmacological activity and good pharmacokinetic properties to the final product.
also plays an important role in the field of chemical industry. Because of its stable structure and reactive activity check point, it can be used to prepare special functional materials. For example, in the synthesis of polymer materials, it is introduced into the polymer backbone as a functional monomer, thereby imparting unique physical and chemical properties to the material, such as improving the solubility and thermal stability of the material, or giving it the adsorption of specific substances. In conclusion, (S) -tert-butyl (1-amino-3- (4-iodophenyl) -1-oxopropyl-2-yl) carbamate has potential applications in many fields of medicine and chemical industry due to its structural characteristics.
What is the synthesis method of (s) -tert-butyl (1-amino-3- (4-iodophenyl) -1-oxopropan-2-yl) carbamate?
To prepare (S) -tert-butyl (1-amino-3- (4-iodophenyl) -1-oxopropyl-2-yl) carbamate, the method of synthesis is quite elegant. First take suitable raw materials, or contain chiral starting materials with specific configurations, to ensure the accuracy of the product configuration.
At the beginning, a compound containing 4-iodophenyl can be selected, and a carbonyl compound with specific activity can be selected. Under suitable reaction conditions, such as in a specific organic solvent, catalyzed by a specific catalyst, the condensation reaction is carried out, and the carbon-carbon bond and related carbonyl structure are constructed to initially build the skeleton of the molecule.
Then, for the conversion of the carbonyl group, or using a specific reducing agent, at a suitable temperature and reaction time, the carbonyl group is moderately reduced to obtain the required hydroxyl intermediate. This process requires strict control of the reaction conditions to prevent excessive reduction or other side reactions.
Then the obtained intermediate is reacted with tert-butyl carbamate reagents. This step also requires attention to the acid-base environment, temperature and other factors of the reaction. A suitable base can be used as an acid binding agent to promote the reaction towards the direction of generating the target product.
After each step of the reaction, separation and purification methods such as column chromatography and recrystallization are required to remove impurities and improve the purity of the product. In this way, (S) -tert-butyl (1-amino-3- (4-iodophenyl) -1-oxo-propyl-2-yl) carbamate can be prepared by multiple steps of delicate reaction and fine operation.
What are the physicochemical properties of (s) -tert-butyl (1-amino-3- (4-iodophenyl) -1-oxopropan-2-yl) carbamate?
(S) -tert-butyl (1-amino-3- (4-iodophenyl) -1-oxypropyl-2-yl) carbamate, which is an organic compound, its physical and chemical properties are quite important.
Looking at its physical properties, under normal circumstances, this compound may be a solid, because many carbamate compounds with similar structures are mostly solid. Its melting point is related to purity, and the melting point of pure ones is stable, which can be used as the basis for identification. And its solubility varies in different solvents. It may have a certain solubility in polar organic solvents such as ethanol and dichloromethane, but its solubility in water may be limited. Although there are polar groups in its molecular structure, non-polar parts such as tert-butyl also affect its water solubility.
On its chemical properties, the structure of carbamate makes it reactive to a certain extent. Amino groups can participate in nucleophilic substitution reactions, react with acyl halides, acid anhydrides, etc., to form corresponding amide derivatives. At the same time, carbonyl groups can undergo addition reactions with nucleophiles, such as with alcohols under acid or base catalysis, or to form acetals or ketones. The iodine atom on the benzene ring can participate in many organic reactions, such as Suzuki reaction, Ullman reaction, etc., to construct carbon-carbon bonds to synthesize more complex organic molecules. In addition, the existence of the chiral center of the compound makes it have potential application value in the field of asymmetric synthesis and chiral drug research, and different configurations may have significant differences in biological activities.
What is the market outlook for -tert-butyl (1-amino-3- (4-iodophenyl) -1-oxopropan-2-yl) carbamate?
Nowadays, there are (S) -tert-butyl (1-amino-3- (4-iodophenyl) -1-oxopropyl-2-yl) carbamate, and its market prospects are related to many aspects. Let me elaborate.
Looking at its structure, it contains iodophenyl, amino, carbamate and other groups, and its unique structure endows it with diverse potential characteristics. From the medical field, iodine-containing structures are often used in radiopharmaceuticals, or can be modified for diagnostic imaging to track lesions and locate them accurately. This compound may be used as a lead compound, and after rational structure optimization, a new type of therapeutic drug can be developed, which will benefit human health and well-being, and the prospect may be bright.
In the field of materials, it contains aryl structure or endows it with special optical and electrical properties. If its amino group and carbamate can participate in the polymerization reaction, or can prepare polymer materials with unique properties, such as used in high-end fields such as photoelectric display and sensors, the market potential should not be underestimated.
However, its market prospects also have challenges. The synthesis process may be complex and expensive, affecting large-scale production and marketing activities. And the market competition is fierce. If new compounds want to stand out, they need to be better than congeneric products in terms of performance, cost, safety, etc.
Overall, (S) -tert-butyl (1-amino-3- (4-iodophenyl) -1-oxypropyl-2-yl) carbamate has considerable addressable market prospects, but it is necessary for scientific research and industry to work together to overcome synthesis and application problems in order to shine and occupy a place in the market.
