S Tert Butyl 2 5 Iodo 1h Imidazol 2 Yl Pyrrolidine 1 Carboxylate
Iodobenzene

(s)-tert-butyl 2-(5-iodo-1h-imidazol-2-yl)pyrrolidine-1-carboxylate

Fengxi Chemical

Specifications

HS Code

502839

Chemical Formula C13H19IN4O2
Molar Mass 390.22 g/mol
Appearance Solid (predicted)
Solubility Soluble in organic solvents like dichloromethane, chloroform (predicted)
Purity Typically high purity for research use, e.g., >95% (assumed)
Stability Stable under normal conditions but may be sensitive to light and air due to iodine
Chemical Formula C14H20IN3O2
Molar Mass 391.23 g/mol
Appearance Solid (predicted)
Physical State At Room Temperature Solid
Solubility In Water Low (due to the non - polar tert - butyl and organic ring structures)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform (due to its organic nature)
Pka N/A (no obvious acidic or basic functional groups for common pKa determination)
Stability Stable under normal conditions, but sensitive to light (iodine - containing compounds can be light - sensitive)
Chemical Formula C14H20IN3O2
Molecular Weight 391.23
Appearance Solid (predicted)
Solubility Solubility in organic solvents like dichloromethane (predicted)
Chemical Formula C13H18IN3O2
Molecular Weight 391.205
Iupac Name tert - butyl 2 - (5 - iodo - 1H - imidazol - 2 - yl)pyrrolidine - 1 - carboxylate
Appearance Solid (predicted)
Solubility Soluble in organic solvents (predicted)
Polar Surface Area 68.17 Ų
Packing & Storage
Packing 10 grams of (s)-tert - butyl 2-(5 - iodo - 1h - imidazol - 2 - yl)pyrrolidine - 1 - carboxylate in sealed vial.
Storage Store (s)-tert - butyl 2-(5 - iodo - 1H - imidazol - 2 - yl)pyrrolidine - 1 - carboxylate in a cool, dry place, away from direct sunlight. Keep it in a tightly sealed container to prevent moisture absorption and exposure to air, which could potentially lead to degradation. Store in a location separate from incompatible substances, following proper chemical storage regulations.
Shipping ( S )-tert -butyl 2-(5 -iodo -1H -imidazol -2 -yl)pyrrolidine -1 -carboxylate is shipped with proper packaging to prevent breakage. It follows strict chemical transport regulations, ensuring safe and timely delivery.
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(s)-tert-butyl 2-(5-iodo-1h-imidazol-2-yl)pyrrolidine-1-carboxylate (s)-tert-butyl 2-(5-iodo-1h-imidazol-2-yl)pyrrolidine-1-carboxylate (s)-tert-butyl 2-(5-iodo-1h-imidazol-2-yl)pyrrolidine-1-carboxylate
General Information
Frequently Asked Questions
What is the chemical structure of (s) -tert-butyl 2- (5-iodo-1h-imidazol-2-yl) pyrrolidine-1-carboxylate?
(S) -tert-butyl 2- (5-iodine-1H-imidazole-2-yl) pyrrolidine-1-carboxylate, which is an organic compound. To understand its chemical structure, it is necessary to look at the composition of each part.
First, "tert-butyl" is a branched-chain alkyl group containing four carbon atoms, which has a specific spatial resistance and chemical properties. " Pyrrolidine-1-formate ", pyrrolidine is a nitrogen-containing five-membered heterocyclic ring, and" -1-formate "shows that there is a formate group attached to the first position of pyrrolidine, which constitutes the core cyclic structure of the compound and affects the overall rigidity and reactivity of the molecule.
Look at" (5-iodine-1H-imidazole-2-yl) "again, imidazole is a five-membered heterocyclic ring containing two nitrogen atoms, 5-iodine indicates that there is an iodine atom attached to the fifth position of the imidazole ring, and 2-yl indicates that the second position of the imidazole ring is partially connected to Iodine atoms have a large atomic radius and electronegativity, which have a significant impact on the physical and chemical properties of compounds, such as enhancing molecular polarity, affecting their solubility in different solvents, and also affecting reactivity and selectivity.
In summary, the chemical structure of (s) -tert-butyl 2- (5-iodine-1H-imidazole-2-yl) pyrrolidine-1-carboxylate is composed of tert-butyl, pyrrolidine-1-carboxylate and 5-iodine-1H-imidazole-2-yl by a specific connection method, and the interaction of each part endows the compound with unique chemical properties and reactivity.
What are the physical properties of (s) -tert-butyl 2- (5-iodo-1h-imidazol-2-yl) pyrrolidine-1-carboxylate?
(S) -tert-butyl 2- (5-iodine-1H-imidazole-2-yl) pyrrolidine-1-carboxylic acid ester has many physical properties. Its appearance is often a specific form, mostly white to off-white solid powder, which is due to the interaction of atoms in the molecular structure and forms a stable aggregate state under normal conditions.
In terms of melting point, it is finely determined to be in a specific temperature range, which is due to the magnitude and characteristics of the intermolecular forces. In the molecule, tert-butyl and imidazolyl interact with pyrrolidine to build a specific lattice structure. It needs to absorb specific energy to break the lattice and cause it to melt.
Solubility is also a key property. In organic solvents, such as common chloroform and dichloromethane, it exhibits good solubility. Interactions such as van der Waals force and hydrogen bond can be formed between the molecular structure and the organic solvent molecules, so that the solute molecules are uniformly dispersed in the solvent. However, in water, the solubility is poor. Due to the large proportion of hydrophobic groups in the molecular structure, the force between water molecules is weak, and it is difficult to form a homogeneous system with water.
In addition, the density of the substance is moderate, depending on its molecular weight and molecular accumulation mode. Stable at room temperature and pressure, the structure may change under specific conditions, such as high temperature, strong acid and alkali environment, because the stability of the intramolecular chemical bonds under such extreme conditions is challenged, or chemical reactions are caused, resulting in changes in the properties of substances.
What is the synthesis method of (s) -tert-butyl 2- (5-iodo-1h-imidazol-2-yl) pyrrolidine-1-carboxylate?
To prepare (s) -tert-butyl-2- (5-iodine-1H-imidazole-2-yl) pyrrolidine-1-carboxylic acid ester, the synthesis method is as follows.
First, appropriate starting materials are taken, and pyrrolidine is used as the base, and a specific substituent is introduced at its 2-position, while the tert-butyl-1-carboxylic acid ester group is first added to protect the nitrogen atom of pyrrolidine. As for the 5-iodine-1H-imidazole-2-base part, it can be gradually constructed by multi-step reaction.
The first step may require a specific functionalization reaction of pyrrolidine, and through suitable reagents and conditions, an activity check point can be created at its 2-position for further reaction. This activity check point can react with intermediates containing imidazole structures. When preparing an imidazole intermediate, an imidazole ring can be constructed first, and then iodine atoms can be introduced at the 5-position. The method of introducing iodine atoms, or a nucleophilic substitution reaction can be used, and a suitable iodine-containing reagent can be used to react in a suitable base and solvent system.
When the pyrrolidine derivative containing suitable substituents and the 5-iodine-1H-imidazole-2-yl intermediate are prepared respectively, the two are coupled. This coupling reaction requires the selection of appropriate catalysts, bases and reaction solvents to promote the effective combination of the two to form the target product (s) -tert-butyl 2- (5-iodine-1H-imidazole-2-yl) pyrrolidine-1-carboxylate. During the reaction process, the reaction process needs to be closely monitored to ensure that the reaction reaches the desired level by means such as thin layer chromatography. After the reaction is completed, it needs to be separated and purified to obtain high-purity products. Methods such as column chromatography and recrystallization can be used for the purification of the products.
What are the application fields of (s) -tert-butyl 2- (5-iodo-1h-imidazol-2-yl) pyrrolidine-1-carboxylate?
(S) -tert-butyl 2- (5-iodine-1H-imidazole-2-yl) pyrrolidine-1-carboxylic acid ester has a wide range of application fields. In the field of medicinal chemistry, this compound may be used as a key intermediate to create drugs with specific biological activities. With its unique molecular structure, it can interact with specific targets in organisms, or regulate physiological processes, or intervene in pathological mechanisms, and has great potential in disease treatment, such as the development of anti-cancer drugs, or by virtue of its structural characteristics, it can target specific receptors or signaling pathways of cancer cells to inhibit tumor growth.
In the field of organic synthesis, it is also an indispensable component. Chemists can modify and expand its structure through various chemical reactions to synthesize more complex and diverse organic molecules. Its special functional groups, such as imidazolyl and pyrrolidinyl, provide many possibilities for organic synthesis, and can participate in a variety of bonding reactions to construct novel carbon-carbon or carbon-heteroatom bonds, enabling the creation of new materials or functional molecules.
Furthermore, in chemical biology research, the compound may be used as a probe molecule. Through its specific combination with biomacromolecules, researchers can gain insight into the microscopic biochemical processes in organisms, clarify the mechanism of protein-ligand interactions, and open up new paths for life science research. In short, (s) -tert-butyl 2- (5-iodine-1H-imidazole-2-yl) pyrrolidine-1-carboxylate has shown important application value in many scientific fields, providing strong support for related research and technological development.
(S) -tert-butyl 2- (5-iodo-1h-imidazol-2-yl) What is the market outlook for pyrrolidine-1-carboxylate?
There are currently compounds (S) -tert-butyl2- (5-iodine-1H-imidazole-2-yl) pyrrolidine-1-carboxylate, and their market prospects are related to many aspects.
Looking at this compound, it may have promising prospects in the field of pharmaceutical research and development. The structure of Geinimidazole and pyrrolidine is often the key to the active ingredients of drugs. The imidazole group substituted by 5-iodine may enhance its interaction with biological targets and endow it with unique pharmacological activity. Therefore, if the R & D team sees its potential, it can develop new drugs to target specific diseases, such as certain inflammatory and tumor-related targets, or open up new therapeutic avenues, and then gain a place in the pharmaceutical market.
In the field of chemical synthesis, it also has potential. As an organic intermediate with a special structure, it may lay the foundation for the synthesis of more complex and high-value-added compounds. With its unique structure, it may open up novel synthesis routes, attracting chemical companies to explore and utilize, and contributing to the innovation of fine chemical products.
However, its market prospects are not smooth. R & D costs are high, and huge capital investment is required from laboratory research to clinical and clinical trials. And the competition is fierce. The pharmaceutical and chemical industries are full of talents and new products. If they fail to stand out, they may be overwhelmed by the market wave.
Overall, (S) -tert-butyl2- (5-iodine-1H-imidazole-2-yl) pyrrolidine-1-carboxylate has potential, but in order to emerge in the market, it is still necessary for developers and enterprises to accurately grasp and break through many barriers in order to open up a vast world.